GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit)

 KIT_CHICK               Reviewed;         960 AA.
Q08156;
01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
01-FEB-1995, sequence version 1.
03-JUL-2019, entry version 155.
RecName: Full=Mast/stem cell growth factor receptor Kit;
Short=SCFR;
EC=2.7.10.1;
AltName: Full=Proto-oncogene c-Kit;
AltName: Full=Tyrosine-protein kinase Kit;
Flags: Precursor;
Name=KIT;
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=White leghorn; TISSUE=Brain;
PubMed=7685729; DOI=10.1016/0378-1119(93)90571-J;
Sasaki E., Okamura H., Chikamune T., Kanai Y., Watanabe M., Naito M.,
Sakurai M.;
"Cloning and expression of the chicken c-kit proto-oncogene.";
Gene 128:257-261(1993).
-!- FUNCTION: Tyrosine-protein kinase that acts as cell-surface
receptor for the cytokine KITLG/SCF and plays an essential role in
the regulation of cell survival and proliferation, hematopoiesis,
stem cell maintenance, gametogenesis, mast cell development,
migration and function, and in melanogenesis. In response to
KITLG/SCF binding, KIT can activate several signaling pathways.
Promotes phosphorylation of PIK3R1, the regulatory subunit of
phosphatidylinositol 3-kinase, and subsequent activation of the
kinase AKT1. Activated KIT also transmits signals via GRB2 and
activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or
MAPK3/ERK1. Promotes activation of STAT family members STAT1,
STAT3, STAT5A and STAT5B. KIT promotes activation of PLCG1,
leading to the production of the cellular signaling molecules
diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is
modulated by protein phosphatases, and by rapid internalization
and degradation of the receptor (By similarity). {ECO:0000250}.
-!- CATALYTIC ACTIVITY:
Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-
tyrosyl-[protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136,
Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
ChEBI:CHEBI:46858, ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
EC=2.7.10.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10028};
-!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
protein.
-!- TISSUE SPECIFICITY: High in the brain and testes and also present
in the bursa of Fabricus, heart, kidney, lung, spleen thymus and
ovary.
-!- PTM: Ubiquitinated. KIT is rapidly ubiquitinated after
autophosphorylation induced by KITLG/SCF binding, leading to
internalization and degradation. {ECO:0000250}.
-!- PTM: Autophosphorylated on tyrosine residues. KITLG/SCF binding
promotes autophosphorylation. Phosphorylated tyrosine residues are
important for interaction with specific binding partners (By
similarity). {ECO:0000250}.
-!- SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein
kinase family. CSF-1/PDGF receptor subfamily.
{ECO:0000255|PROSITE-ProRule:PRU00159}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; D13225; BAA02506.1; -; mRNA.
PIR; JN0677; JN0677.
RefSeq; NP_989692.1; NM_204361.1.
SMR; Q08156; -.
STRING; 9031.ENSGALP00000022531; -.
PaxDb; Q08156; -.
PRIDE; Q08156; -.
Ensembl; ENSGALT00000047850; ENSGALP00000051217; ENSGALG00000038634.
GeneID; 378783; -.
KEGG; gga:378783; -.
CTD; 3815; -.
eggNOG; KOG0200; Eukaryota.
eggNOG; COG0515; LUCA.
GeneTree; ENSGT00940000155626; -.
HOGENOM; HOG000112008; -.
InParanoid; Q08156; -.
KO; K05091; -.
OrthoDB; 236292at2759; -.
PhylomeDB; Q08156; -.
BRENDA; 2.7.10.1; 1306.
PRO; PR:Q08156; -.
Proteomes; UP000000539; Chromosome 4.
Bgee; ENSGALG00000013925; Expressed in 9 organ(s), highest expression level in brain.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IEA:Ensembl.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0042629; C:mast cell granule; IEA:GOC.
GO; GO:0043235; C:receptor complex; IBA:GO_Central.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0019955; F:cytokine binding; IEA:Ensembl.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0002020; F:protease binding; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
GO; GO:0005020; F:stem cell factor receptor activity; IEA:Ensembl.
GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IBA:GO_Central.
GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
GO; GO:0030183; P:B cell differentiation; IBA:GO_Central.
GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Ensembl.
GO; GO:0002371; P:dendritic cell cytokine production; IEA:Ensembl.
GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
GO; GO:0038162; P:erythropoietin-mediated signaling pathway; IEA:Ensembl.
GO; GO:0038093; P:Fc receptor signaling pathway; IEA:Ensembl.
GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IBA:GO_Central.
GO; GO:0035701; P:hematopoietic stem cell migration; IEA:Ensembl.
GO; GO:0002327; P:immature B cell differentiation; IEA:Ensembl.
GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
GO; GO:0038109; P:Kit signaling pathway; IBA:GO_Central.
GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0008584; P:male gonad development; IEA:Ensembl.
GO; GO:0002551; P:mast cell chemotaxis; IEA:Ensembl.
GO; GO:0032762; P:mast cell cytokine production; IEA:Ensembl.
GO; GO:0043303; P:mast cell degranulation; IEA:Ensembl.
GO; GO:0060374; P:mast cell differentiation; IEA:Ensembl.
GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
GO; GO:0097326; P:melanocyte adhesion; IEA:Ensembl.
GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
GO; GO:0097324; P:melanocyte migration; IEA:Ensembl.
GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0043069; P:negative regulation of programmed cell death; IEA:Ensembl.
GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IBA:GO_Central.
GO; GO:0008284; P:positive regulation of cell population proliferation; IBA:GO_Central.
GO; GO:0051091; P:positive regulation of DNA-binding transcription factor activity; IEA:Ensembl.
GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IBA:GO_Central.
GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
GO; GO:0043406; P:positive regulation of MAP kinase activity; IBA:GO_Central.
GO; GO:0043410; P:positive regulation of MAPK cascade; IBA:GO_Central.
GO; GO:0046427; P:positive regulation of receptor signaling pathway via JAK-STAT; IBA:GO_Central.
GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IEA:Ensembl.
GO; GO:1905065; P:positive regulation of vascular smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
GO; GO:0009314; P:response to radiation; IEA:Ensembl.
GO; GO:0007286; P:spermatid development; IEA:Ensembl.
GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
Gene3D; 2.60.40.10; -; 5.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR013151; Immunoglobulin.
InterPro; IPR011009; Kinase-like_dom_sf.
InterPro; IPR000719; Prot_kinase_dom.
InterPro; IPR017441; Protein_kinase_ATP_BS.
InterPro; IPR027263; SCGF_receptor.
InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
InterPro; IPR008266; Tyr_kinase_AS.
InterPro; IPR020635; Tyr_kinase_cat_dom.
InterPro; IPR001824; Tyr_kinase_rcpt_3_CS.
Pfam; PF00047; ig; 1.
Pfam; PF07714; Pkinase_Tyr; 1.
PIRSF; PIRSF500951; SCGF_recepter; 1.
SMART; SM00409; IG; 4.
SMART; SM00408; IGc2; 3.
SMART; SM00219; TyrKc; 1.
SUPFAM; SSF48726; SSF48726; 5.
SUPFAM; SSF56112; SSF56112; 1.
PROSITE; PS50835; IG_LIKE; 1.
PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PROSITE; PS00240; RECEPTOR_TYR_KIN_III; 1.
2: Evidence at transcript level;
ATP-binding; Cell membrane; Complete proteome; Disulfide bond;
Glycoprotein; Immunoglobulin domain; Kinase; Magnesium; Membrane;
Metal-binding; Nucleotide-binding; Phosphoprotein; Proto-oncogene;
Receptor; Reference proteome; Repeat; Signal; Transferase;
Transmembrane; Transmembrane helix; Tyrosine-protein kinase;
Ubl conjugation.
SIGNAL 1 24 {ECO:0000255}.
CHAIN 25 960 Mast/stem cell growth factor receptor
Kit.
/FTId=PRO_0000016756.
TOPO_DOM 25 511 Extracellular. {ECO:0000255}.
TRANSMEM 512 532 Helical. {ECO:0000255}.
TOPO_DOM 533 960 Cytoplasmic. {ECO:0000255}.
DOMAIN 27 102 Ig-like C2-type 1.
DOMAIN 111 194 Ig-like C2-type 2.
DOMAIN 201 294 Ig-like C2-type 3.
DOMAIN 303 396 Ig-like C2-type 4.
DOMAIN 399 497 Ig-like C2-type 5.
DOMAIN 575 913 Protein kinase. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
NP_BIND 582 589 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
NP_BIND 657 663 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
ACT_SITE 777 777 Proton acceptor. {ECO:0000255|PROSITE-
ProRule:PRU00159, ECO:0000255|PROSITE-
ProRule:PRU10028}.
METAL 554 554 Magnesium. {ECO:0000250}.
METAL 782 782 Magnesium. {ECO:0000250}.
METAL 795 795 Magnesium. {ECO:0000250}.
BINDING 609 609 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
BINDING 781 781 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
MOD_RES 554 554 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
MOD_RES 556 556 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
MOD_RES 689 689 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
MOD_RES 706 706 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
MOD_RES 808 808 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
MOD_RES 921 921 Phosphotyrosine; by autocatalysis.
{ECO:0000250}.
CARBOHYD 76 76 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 135 135 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 149 149 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 269 269 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 286 286 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 306 306 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 318 318 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 338 338 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 343 343 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 356 356 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 453 453 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 469 469 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 45 87 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 126 175 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 141 172 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 222 276 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 414 481 {ECO:0000255|PROSITE-ProRule:PRU00114}.
SEQUENCE 960 AA; 107312 MW; 0E93850527AB68F6 CRC64;
MEGAHLAWEL AHAVLLLSLI PAGGSVPHEE SSLVVNKGEE LRLKCNEEGP VTWNFQNSDP
SAKTRISNEK EWHTKNATIR DIGRYECKSK GSIVNSFYVF VKDPNVLFLV DSLIYGKEDS
DILLVCPLTD PDVLNFTLRK CDGKPLPKNM TFIPNPQKGI IIKNVQRSFK GCYQCLAKHN
GVEKISEHIF LNVRPVHKAL PVITLSKSYE LLKEGEEFEV TCIITDVDSS VKASWISYKS
AIVTSKSRNL GDYGYERKLT LNIRSVGVND SGEFTCQAEN PFGKTNATVT LKALAKGFVR
LFATMNTTID INAGQNGNLT VEYEAYPKPK EEVWMYMNET LQNSSDHYVK FKTVGNNSYT
SELHLTRLKG TEGGIYTFFV SNSDASSSVT FNVYVKTKPE ILTLDMLGND ILQCVATGFP
APTIYWYFCP GTEQRCLDSP TISPMDVKVS YTNSSVPSFE RILVESTVNA SMFKSTGTIC
CEASSNGDKS SVFFNFAIKE QIRTHTLFTP LLIAFGVAAG LMCIIVMILV YIYLQKPKYE
VQWKVVEEIN GNNYVYIDPT QLPYDHKWEF PRNRLSFGKT LGAGAFGKVV EATAYGLFKS
DAAMTVAVKM LKPSAHLTER EALMSELKVL SYLGNHINIV NLLGACTIGG PTLVITEYCC
YGDLLNFLRR KRDSFICPKH EEHAEAAVYE NLLHQAEPTA DAVNEYMDMK PGVSYAVPPK
ADKKRPVKSG SYTDQDVTLS MLEDDELALD VEDLLSFSYQ VAKGMSFLAS KNCIHRDLAA
RNILLTHGRI TKICDFGLAR DIRNDSNYVV KGNARLPVKW MAPESIFNCV YTFESDVWSY
GILLWELFSL GSSPYPGMPV DSKFYKMIKE GYRMFSPECS PPEMYDIMKS CWDADPLQRP
TFKQIVQLIE QQLSDNAPRV YANFSTPPST QGNATDHSVR INSVGSSASS TQPLLVREDV


Related products :

Catalog number Product name Quantity
E0121h ELISA kit Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feli 96T
E0121h ELISA Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feline sa 96T
U0121h CLIA Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feline sar 96T
E0121p ELISA kit KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
E0121p ELISA KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
U0121p CLIA KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
E0121b ELISA Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121b ELISA kit Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121m ELISA Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
U0121b CLIA Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121m ELISA kit Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
U0121m CLIA Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
15-288-21114 Mast_stem cell growth factor receptor - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.1 mg
15-288-21114 Mast_stem cell growth factor receptor - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.05 mg
U0121c CLIA Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA kit Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA kit Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
U0121c CLIA Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
U0978r CLIA Epidermal growth factor receptor-related protein,Erbb2,Neu,p185erbB2,p185neu,Proto-oncogene c-ErbB-2,Proto-oncogene Neu,Rat,Rattus norvegicus,Receptor tyrosine-protein kinase erbB-2 96T
E0978r ELISA Epidermal growth factor receptor-related protein,Erbb2,Neu,p185erbB2,p185neu,Proto-oncogene c-ErbB-2,Proto-oncogene Neu,Rat,Rattus norvegicus,Receptor tyrosine-protein kinase erbB-2 96T
E0978r ELISA kit Epidermal growth factor receptor-related protein,Erbb2,Neu,p185erbB2,p185neu,Proto-oncogene c-ErbB-2,Proto-oncogene Neu,Rat,Rattus norvegicus,Receptor tyrosine-protein kinase erbB-2 96T
32-138 C-kit (CD117,145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c 0.1 mL
10-054-165009 cKit HUMAN - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen 0.01 mg
Pathways :
WP1235: Signaling of Hepatocyte Growth Factor Receptor
WP444: Signaling of Hepatocyte Growth Factor Receptor
WP1046: Signaling of Hepatocyte Growth Factor Receptor
WP94: Signaling of Hepatocyte Growth Factor Receptor
WP1206: Signaling of Hepatocyte Growth Factor Receptor
WP810: Signaling of Hepatocyte Growth Factor Receptor
WP313: Signaling of Hepatocyte Growth Factor Receptor
WP193: Signaling of Hepatocyte Growth Factor Receptor
WP927: Signaling of Hepatocyte Growth Factor Receptor
WP1162: Signaling of Hepatocyte Growth Factor Receptor
WP1869: Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP480: T Cell Receptor Signaling Pathway
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP780: T Cell Receptor Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1345: T Cell Receptor Signaling Pathway
WP474: Endochondral Ossification
WP1714: Tyrosine metabolism
WP1130: T Cell Receptor Signaling Pathway
WP2272: Pathogenic Escherichia coli infection
WP352: T Cell Receptor Signaling Pathway
WP894: T Cell Receptor Signaling Pathway
WP23: B Cell Receptor Signaling Pathway
WP794: B Cell Receptor Signaling Pathway
WP285: B Cell Receptor Signaling Pathway

Related Genes :
[KIT SCFR] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)
[Kit Sl] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[KIT] Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
[kita kit sparse] Mast/stem cell growth factor receptor kita (SCFR) (EC 2.7.10.1) (Tyrosine-protein kinase Kit)
[Kitlg Kitl Mgf Sl Slf] Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Steel factor) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[kit krk1] Mast/stem cell growth factor receptor-related protein Kit (EC 2.7.10.1) (Kit-related kinase 1) (xKrk1) (Tyrosine-protein kinase kit)
[KITLG MGF SCF] Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[Kitlg Kitl Mgf] Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[KITLG MGF] Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[FES FPS] Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)
[ABL1 ABL JTK7] Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
[FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR] Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
[EGFR ERBB ERBB1 HER1] Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
[MET] Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
[FER TYK3] Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)
[Erbb2 Neu] Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Epidermal growth factor receptor-related protein) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (p185erbB2) (p185neu) (CD antigen CD340)
[SRC] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[LCK] Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
[SRC SRC1] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[KITLG SCF] Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[Met] Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
[Lyn] Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
[LYN JTK8] Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
[Fyn] Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)

Bibliography :