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Metalloendopeptidase (EC 3 4 24 -)

 F6Z0W2_HORSE            Unreviewed;      1044 AA.
F6Z0W2;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
10-APR-2019, sequence version 2.
10-APR-2019, entry version 65.
RecName: Full=Metalloendopeptidase {ECO:0000256|RuleBase:RU361183};
EC=3.4.24.- {ECO:0000256|RuleBase:RU361183};
Name=BMP1 {ECO:0000313|Ensembl:ENSECAP00000019709,
ECO:0000313|VGNC:VGNC:15844};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000019709, ECO:0000313|Proteomes:UP000002281};
[1] {ECO:0000313|Ensembl:ENSECAP00000019709, ECO:0000313|Proteomes:UP000002281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000019709,
ECO:0000313|Proteomes:UP000002281};
PubMed=19892987; DOI=10.1126/science.1178158;
Broad Institute Genome Sequencing Platform;
Broad Institute Whole Genome Assembly Team;
Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H.,
Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N.,
Penedo M.C.T., Raison J.M., Sharpe T., Vogel J., Andersson L.,
Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J.,
Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J.,
Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R.,
Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F.,
Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L.,
Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M.,
White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
"Genome sequence, comparative analysis, and population genetics of the
domestic horse.";
Science 326:865-867(2009).
[2] {ECO:0000313|Ensembl:ENSECAP00000019709}
IDENTIFICATION.
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000019709};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-!- COFACTOR:
Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
Evidence={ECO:0000256|PIRSR:PIRSR001199-2,
ECO:0000256|RuleBase:RU361183};
Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR001199-
2, ECO:0000256|RuleBase:RU361183};
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
-----------------------------------------------------------------------
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RefSeq; XP_005607717.1; XM_005607660.2.
MEROPS; M12.005; -.
PaxDb; F6Z0W2; -.
Ensembl; ENSECAT00000023765; ENSECAP00000019709; ENSECAG00000021675.
GeneID; 100056914; -.
KEGG; ecb:100056914; -.
CTD; 649; -.
VGNC; VGNC:15844; BMP1.
eggNOG; KOG3714; Eukaryota.
eggNOG; ENOG410ZPX7; LUCA.
GeneTree; ENSGT00940000157176; -.
InParanoid; F6Z0W2; -.
KO; K05502; -.
OMA; KGFEASH; -.
OrthoDB; 170905at2759; -.
TreeFam; TF314351; -.
Proteomes; UP000002281; Chromosome 2.
Bgee; ENSECAG00000021675; Expressed in 3 organ(s), highest expression level in liver.
GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-UniRule.
GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
CDD; cd00041; CUB; 5.
CDD; cd04281; ZnMc_BMP1_TLD; 1.
Gene3D; 2.60.120.290; -; 5.
Gene3D; 3.40.390.10; -; 1.
InterPro; IPR015446; BMP_1/tolloid-like.
InterPro; IPR000859; CUB_dom.
InterPro; IPR001881; EGF-like_Ca-bd_dom.
InterPro; IPR013032; EGF-like_CS.
InterPro; IPR000742; EGF-like_dom.
InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
InterPro; IPR018097; EGF_Ca-bd_CS.
InterPro; IPR024079; MetalloPept_cat_dom_sf.
InterPro; IPR001506; Peptidase_M12A.
InterPro; IPR006026; Peptidase_Metallo.
InterPro; IPR035914; Sperma_CUB_dom_sf.
InterPro; IPR034036; ZnMP_TLD/BMP1.
Pfam; PF01400; Astacin; 1.
Pfam; PF00431; CUB; 5.
Pfam; PF07645; EGF_CA; 1.
PIRSF; PIRSF001199; BMP_1/tolloid-like; 1.
PRINTS; PR00480; ASTACIN.
SMART; SM00042; CUB; 5.
SMART; SM00181; EGF; 2.
SMART; SM00179; EGF_CA; 2.
SMART; SM00235; ZnMc; 1.
SUPFAM; SSF49854; SSF49854; 5.
PROSITE; PS00010; ASX_HYDROXYL; 2.
PROSITE; PS01180; CUB; 5.
PROSITE; PS01186; EGF_2; 2.
PROSITE; PS50026; EGF_3; 2.
PROSITE; PS01187; EGF_CA; 2.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002281};
Disulfide bond {ECO:0000256|SAAS:SAAS00601599};
EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076,
ECO:0000256|SAAS:SAAS00032677};
Hydrolase {ECO:0000256|RuleBase:RU361183,
ECO:0000256|SAAS:SAAS01068076};
Metal-binding {ECO:0000256|PIRSR:PIRSR001199-2,
ECO:0000256|RuleBase:RU361183, ECO:0000256|SAAS:SAAS00973795};
Metalloprotease {ECO:0000256|RuleBase:RU361183,
ECO:0000256|SAAS:SAAS01068076};
Protease {ECO:0000256|RuleBase:RU361183,
ECO:0000256|SAAS:SAAS01068076};
Reference proteome {ECO:0000313|Proteomes:UP000002281};
Repeat {ECO:0000256|SAAS:SAAS00792548};
Signal {ECO:0000256|RuleBase:RU361183};
Zinc {ECO:0000256|PIRSR:PIRSR001199-2, ECO:0000256|RuleBase:RU361183,
ECO:0000256|SAAS:SAAS00973802}.
SEQUENCE 1044 AA; 116594 MW; C162E29D99807830 CRC64;
MPGVARLPLP LPLLLWLLLL ARPGRPLDLA DYTYELGEED DSEPLNYKDP CKAVAFLGDI
ALDEEDLRAF QVQQAVDLGQ QAIRRSSIKA AENSSTPICQ STSGQPQRKN RGRWRSRSRS
RRAATSRPER VWPDGVIPFV IGGNFTGSQR AVFRQAMRHW EKHTCVTFLE RTDEDSYIVF
TYRPCGCCSY VGRRGGGPQA ISIGKNCDKF GIVVHELGHV IGFWHEHTRP DRDRHVSIVR
ENIQPGQEYN FLKMELQEVE SLGENYDFDS IMHYARNTFS RGIFLDTIVP KYEVNGVKPP
IGQRTRLSKG DIAQARKLYK CPACGETLQD STGNFSSPEY PNGYSAHMHC VWRISVTPGE
KIILNFTSMD LYRSRLCWYD YVEVRDGFWR KAPLRAICGG DVKKDNGHIQ SPNYPDDYRP
SKVCVWRIQV SEGFHVGLTF QSFEIERHDS CAYDYLEVRD GHSEGSPLIG RYCGYERPDD
IKSTSSRLWL KFVSDGSINK AGFAVNFFKE VDECSRPNRG GCEQRCLNTL GSYKCSCDPG
YELAPDKRRC EAACGGFLTK LNGSITSPGW PKEYPPNKNC IWQLVAPTQY RISLQFDFFE
TEGNDVCKYD FVEVRSGLTA DSKLHGKFCG SEKPEVITSQ YNNMRVEFKS DNTVSKKGFK
AHFFSDKDEC SKDNGGCQQD CVNTFGSYEC QCRSGFVLHD NKHDCKEAGC DHKVTSTSGT
ITSPNWPDKY PSKKECTWAI SSTPGHRVKL TFTEMDIESQ PECAYDHLEV YDGRDAKADI
LGRFCGSKKP EPILATGSRM FLRFYSDNSV QRKGFQASHS TECGGQVQAE VKTKDLYSHA
QFGDNNYPGG VDCEWVIVAE EGYGVELVFQ TFEVEEETDC GYDYMELFDG YDSTAPRLGR
YCGSGVRPPR PHPPRPSRAG SRAAVPLRHP AGKGTTARAW PLAGAGRPGV AGGCSQRPSL
SWAVPTQETW SFLADTEVPI ASGTGPALTQ ACSAPVWLGL QGSWHLGRSI ALPLPHRSLA
SVPRQLTRAW SGGGGWGKSQ GPGA


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[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[pyrG A6592_02570 A8M42_16405 A9R57_06965 AC067_22330 AC789_1c31020 ACN002_2797 ACN77_07080 ACN81_20385 ACU57_24415 ACU90_23015 AJ318_22735 AKG99_03555 AM270_00945 AM446_06950 AM464_05605 AM465_10605 AML07_12460 AML35_05300 APT94_17890 APU18_18535 APZ14_09290 ARC77_10140 AU473_08010 AUQ13_17535 AUS26_15660 AW059_10675 AW106_00665 AWP75_20610 AZZ83_003241 B1K96_20050 B7C53_10055 B9M99_21725 B9N33_09475 B9T59_19685 BANRA_01020 BANRA_01301 BANRA_01853 BANRA_03509 BANRA_04184 BANRA_04324 BB545_13920 BE963_03670 BEN53_16995 BET08_07180 BH694_13410 BHF46_05050 BHS81_16640 BHS87_15735 BIQ87_15835 BIU72_09520 BIZ41_16885 BJJ90_05265 BK248_12970 BK292_23205 BK334_11935 BK373_15870 BK375_10085 BK383_11680 BK400_05820 BMT49_17330 BMT53_21250 BMT91_11105 BN17_26661 BTQ04_11510 BTQ06_23845 BUE81_06975 BVL39_12970 BW690_04975 BWP17_05185 BXT93_24405 BZL31_00820 BZL69_02125 C1I57_04860 C2M16_17770 C2U48_20025 C4J69_11655 C4K41_05275 C4M78_00835 C5715_23540 C5N07_06155 C5P01_05005 C5P43_15935 C5P44_09340 C6669_14670 C6986_17750 C6B13_03370 C7235_05745 C7B02_19400 C7B06_11630 C7B07_14530 C7B08_01430 C9E25_03325 CA593_12975 CCZ14_04445 CCZ17_10850 CDL37_13440 CG691_07365 CG692_07005 CG705_05530 CG706_07860 CIJ94_12220 COD30_01795 COD46_07095 CQP61_06810 CR538_05495 CR539_18815 CRE06_03485 CRM83_26360 CRT43_16405 CRT46_16440 CSB64_15850 CT143_09630 CT146_00680 CV83915_03339 CVH05_06295 CWM24_00790 CWS33_03125 CXB56_08765 D0X26_06660 D1900_12730 D2183_19100 D2F89_14380 D3821_11140 D3I61_16000 D3Y67_06430 D6X47_20010 D6Z21_06885 D7Y10_03025 D9D20_04450 D9D23_22915 D9D33_19300 D9D43_17525 D9D65_14225 D9D69_09045 D9D77_00700 D9E30_05150 D9E35_20180 D9F02_13015 D9F06_14905 D9F12_20360 D9F17_11720 D9F21_05730 D9F57_14060 D9G11_10545 D9G22_12025 D9G42_05640 D9G48_11875 D9G53_18355 D9H12_01020 D9H53_12755 D9H66_06795 D9H68_17340 D9H70_12195 D9H84_05175 D9H94_16855 D9I18_10690 D9I20_00375 D9I47_00795 D9I52_20775 D9I82_09360 D9I88_14405 D9I93_14040 D9J03_22055 D9J11_17735 D9J39_15575 D9J44_16360 D9J46_14445 D9J48_09915 D9J60_10045 D9K10_07620 D9L99_02095 DD762_13665 DIV22_29760 DL545_05995 DL800_20505 DM129_10705 DM262_13330 DMZ31_10015 DNQ41_18960 DNR41_08670 DOT75_04395 DP258_16075 DQE83_04685 DQP22_07305 DS732_20695 DS966_06010 DTL43_09355 DTL90_02675 DTM10_03745 DTM25_22630 DTM45_13530 DU284_12985 DU290_05405 DU309_08860 DU326_11595 E2855_03617 EA140_01780 EAI36_21600 EAI42_07155 EAI44_18400 EAI52_12500 EB510_16355 EB553_05185 EB569_00660 EB595_11470 EC1094V2_904 EC3234A_48c00890 EC95NR1_02021 ECONIH1_15890 ECs3640 ED060_03420 ED098_15385 ED124_16450 ED133_03895 ED287_02625 ED600_14885 ED648_01520 ED653_00705 ED944_03505 EEO96_21535 EEP03_03515 EEP23_14050 EF364_03510 EFV06_07140 EGN87_18575 EGT48_09620 EGY17_03100 EIA08_07275 EIA21_04795 EL75_0914 EL79_0915 EL80_0918 ERS085365_02427 ERS085366_03042 ERS085374_03279 ERS085386_03410 ERS085416_02898 ERS139211_02072 ERS150873_02003 ERS150876_01467 FORC28_1110 GJ11_18025 HMPREF3040_01161 HW43_18180 JD73_16335 MJ49_17095 MS6198_30910 MS8345_02965 NCTC10082_03473 NCTC10090_04050 NCTC10418_01701 NCTC10764_00296 NCTC10766_00690 NCTC10767_02309 NCTC11022_02860 NCTC11112_00121 NCTC11181_03277 NCTC12950_01251 NCTC13125_04353 NCTC13127_01436 NCTC13462_04807 NCTC13846_01212 NCTC7152_00995 NCTC7927_01209 NCTC8500_01090 NCTC8960_03783 NCTC9007_03892 NCTC9036_01135 NCTC9037_01243 NCTC9044_00576 NCTC9045_01221 NCTC9050_04166 NCTC9054_01172 NCTC9058_00847 NCTC9062_02131 NCTC9075_01630 NCTC9077_01409 NCTC9081_05851 NCTC9117_01609 NCTC9119_01271 NCTC9434_01004 NCTC9706_03296 NCTC9775_04845 NCTC9777_02704 NCTC9969_01292 PU06_02080 RG28_07675 RK56_023165 SAMEA3472033_01264 SAMEA3472044_02272 SAMEA3472047_00339 SAMEA3472056_05455 SAMEA3472067_02540 SAMEA3472070_01673 SAMEA3472080_03155 SAMEA3472090_00131 SAMEA3472108_00527 SAMEA3472110_03462 SAMEA3472112_03722 SAMEA3472114_02432 SAMEA3472147_03296 SAMEA3484427_03298 SAMEA3484429_03415 SAMEA3484433_01660 SAMEA3484434_01581 SAMEA3485101_02257 SAMEA3485113_02257 SAMEA3752372_03639 SAMEA3752557_03040 SAMEA3752559_02995 SAMEA3752620_01282 SAMEA3753064_02287 SAMEA3753097_02219 SAMEA3753164_01192 SAMEA3753290_02847 SAMEA3753300_01107 SAMEA3753397_04005 SK85_03024 SY51_15605 UC41_20365 UN91_03645 WM48_14990 WQ89_10170 WR15_06090 YDC107_1339] CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)
[hchA A9819_11910 ACN81_03425 AML35_08765 AW059_23935 BANRA_00208 BANRA_00433 BHF46_18455 BMT91_24760 C4J69_22715 C7B08_25495 CR538_10415 D2F89_25795 D3Y67_22910 D9G42_11130 D9H12_21840 D9I52_00260 D9J11_25195 DP258_02540 EC3234A_36c00010 EFV06_13085 NCTC8500_02249 NCTC9037_02122 NCTC9117_02637 NCTC9969_02156 SAMEA3472108_01151 SAMEA3484427_04795 SAMEA3484429_02051 SAMEA3752557_05476 SAMEA3752559_04333] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[hchA A8C65_13880 A9R57_25255 AKG99_20940 AMK83_16550 B7C53_22525 B9M99_11580 B9T59_01945 BJJ90_15205 BMT49_12710 BMT53_00170 BUE81_10670 BW690_17225 BZL69_29425 C2U48_24800 C5715_19445 C5N07_21380 C6669_19295 C7B06_02290 C7B07_03930 CDL37_00765 CG691_19145 CG705_13560 CG706_14580 CIJ94_05515 COD46_23180 CQP61_17160 CRD98_26150 D3I61_11545 D5653_07335 D9D20_21030 D9D23_19420 D9D43_06110 D9D77_14400 D9H68_20750 D9H70_25730 D9H84_23295 DL800_09215 DLU27_07380 DNQ41_14245 DQE83_22775 DTL43_21780 DTM25_06080 DU290_13085 DU321_04440 E2855_02503 EAI36_14435 EC95NR1_00961 ED648_25045 ED653_23400 ED658_13700 ERS085379_01273 ERS085386_05041 HMPREF3040_01583 HW43_13705 NCTC10082_04431 NCTC10418_03071 NCTC10767_03558 NCTC11022_01867 NCTC11126_04427 NCTC11181_05650 NCTC12950_02263 NCTC13462_05714 NCTC8985_00529 NCTC9111_05933 NCTC9703_00277 PU06_24500 SAMEA3472055_03589 SAMEA3472056_01268 SAMEA3472070_00654 SAMEA3472080_04213 SAMEA3472090_03376 SAMEA3472110_00060 SAMEA3472112_00448 SAMEA3752372_00752 UN91_23615 WQ89_10695] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[hchA A8M42_01610 AM465_15370 AZZ83_004235 B9N33_26475 BH694_24485 C1I57_21890 C7B02_06890 CCZ14_26645 CCZ17_22700 CRT43_11430 CT143_08220 D4L90_15900 D6X47_12880 D9D33_15385 D9E30_24120 D9E49_19020 D9F21_16730 D9I20_10460 D9I82_06925 D9J39_24905 D9J46_03345 DNR41_00375 DS966_16070 DU284_14760 DU327_11205 EA140_14775 EEO96_00675 EGN87_21410 ERS085406_02591 NCTC10766_03778 NCTC7928_05955 NCTC8450_02317 NCTC9007_02951 NCTC9075_02834 NCTC9775_01269 SY51_11150 WM48_10115] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[Or22b AN12 DOR22A.2 dor67 Or22A.2 CG4231] Odorant receptor 22b
[Or22a AN11 DOR22A.1 dor53 Or22A.1 CG12193] Odorant receptor 22a
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[Pre C,C C core E PC pre-C pre-C/C PreC preC PreC/C preC/C precore-core HBVgp4] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[lon lon_1 lon_2 A6581_06540 A8C65_09155 A8G17_09470 A8M42_12205 A9819_02150 A9R57_08730 AC067_13940 AC789_1c04390 ACN77_08400 ACN81_24745 ACU57_11790 ACU90_20700 AJ318_07395 AM270_02090 AM446_21265 AM464_19190 AM465_24425 AMK83_09080 AML07_05605 AML35_17195 APT94_11405 APU18_24755 APZ14_19130 AUQ13_18305 AUS26_08525 AW059_13755 AW106_10030 AWP75_24635 AZZ83_000203 B1K96_09680 B7C53_07945 B9M99_03985 B9N33_08900 B9T59_05700 BANRA_00867 BANRA_01969 BANRA_02043 BANRA_03457 BANRA_03641 BANRA_04310 BB545_15795 BE963_16350 BER14_14325 BET08_18215 BH694_02335 BHF46_21220 BHS81_02650 BIQ87_02425 BIU72_03070 BIZ41_19875 BJJ90_20055 BK248_01840 BK292_14395 BK334_05695 BK373_01080 BK375_01675 BK383_14710 BK400_22925 BMT49_03495 BMT53_08160 BMT91_05050 BN17_02431 BTQ06_01040 BUE81_06550 BVL39_00620 BW690_06825 BXT93_14065 BZL31_10455 BZL69_16545 C1I57_02830 C2M16_02950 C4J69_09250 C4M78_17970 C5715_07650 C5N07_12995 C5P01_16055 C5P43_02540 C6669_02490 C6986_02640 C6B13_10210 C7235_18620 C7B06_13115 C7B07_14925 C7B08_06455 C9E25_04330 CA593_00935 CCZ14_02195 CCZ17_03875 CDL37_08925 CG692_04795 CG705_03025 CG706_02860 CIJ94_10835 COD30_15795 COD46_04600 CQP61_20635 CR538_19245 CR539_06435 CRD98_01930 CRT43_02425 CRT46_02355 CSB64_03555 CT143_00390 CT146_15985 CWM24_20160 CWS33_13550 CXB56_21765 D0X26_07675 D1900_17610 D2183_00880 D2F89_19370 D3821_12655 D3I61_03100 D3Y67_14595 D4L90_12180 D5653_01895 D5F38_02760 D6X47_16730 D8K42_15275 D9D20_11240 D9D23_03440 D9D33_05815 D9D43_21565 D9D65_06085 D9D69_10170 D9D77_05845 D9E22_05125 D9E30_03120 D9E34_09980 D9E35_07020 D9E49_06700 D9F02_09460 D9F06_06685 D9F12_04140 D9F17_03270 D9F21_02155 D9F57_07485 D9G11_06315 D9G22_08220 D9H53_20830 D9H66_06030 D9H84_09300 D9H94_07265 D9I18_05150 D9I20_07000 D9I47_07695 D9I82_14705 D9I88_11055 D9I93_02200 D9J03_07390 D9J11_02395 D9J39_12040 D9J44_06085 D9J46_04320 D9J48_16620 D9K10_09365 DD762_17560 DIV22_26545 DL545_18880 DL800_04145 DLU27_08400 DM129_08665 DNQ41_06120 DNQ45_04780 DOT75_07785 DP258_04840 DQE83_14690 DS732_07170 DS966_18225 DTL43_07145 DTM10_06325 DTM25_22445 DTM45_11225 DU309_22890 DU326_08350 DU327_00950 DU333_14745 DV750_08485 E2855_00491 EA140_15345 EAI36_19095 EAI42_06530 EAI44_11230 EAI52_03190 EB553_14860 EB569_14055 EB595_05425 EC1094V2_3409 EC3234A_4c01080 EC95NR1_04662 ECONIH1_02385 ED287_10370 ED600_06055 ED648_01980 ED653_08705 ED658_02475 EEO96_07040 EEP23_01295 EF364_13940 EFV06_11505 EGY17_15430 EIA08_09740 ERS085365_02395 ERS085374_02327 ERS085379_01165 ERS085383_00971 ERS085406_02176 ERS085416_01921 ERS139211_01924 ERS150876_00617 FORC28_4645 GJ11_02625 HMPREF3040_03444 HW43_05825 MJ49_04235 MS6198_04430 MS8345_00443 NCTC10082_01029 NCTC10090_01830 NCTC10418_05598 NCTC10764_05303 NCTC10766_05771 NCTC11022_05186 NCTC11181_01095 NCTC13462_01885 NCTC13846_03631 NCTC7152_03832 NCTC7922_06176 NCTC7927_04214 NCTC7928_04997 NCTC8179_01705 NCTC8196_01204 NCTC8959_05066 NCTC8960_01264 NCTC9007_00214 NCTC9036_03791 NCTC9037_03909 NCTC9050_01704 NCTC9054_04215 NCTC9055_00655 NCTC9058_03169 NCTC9062_04515 NCTC9111_03927 NCTC9117_04741 NCTC9434_02860 NCTC9703_03170 NCTC9706_01065 NCTC9777_00122 NCTC9969_03979 PU06_02695 RG28_02630 RK56_026450 RX35_02110 SAMEA3472033_03457 SAMEA3472044_00416 SAMEA3472047_02150 SAMEA3472055_02113 SAMEA3472067_03237 SAMEA3472070_02234 SAMEA3472080_01763 SAMEA3472090_01765 SAMEA3472108_01909 SAMEA3472110_00680 SAMEA3472112_02916 SAMEA3484427_03496 SAMEA3484429_01936 SAMEA3484433_02327 SAMEA3485113_01252 SAMEA3752372_02700 SAMEA3752557_00263 SAMEA3752559_02850 SAMEA3752620_00833 SAMEA3753097_00463 SAMEA3753164_00266 SAMEA3753300_00505 SAMEA3753397_02130 SK85_00464 SY51_02300 UC41_11885 UN86_09160 UN91_18465 WM48_02515 WR15_04115 YDC107_3709] Lon protease (EC 3.4.21.53) (ATP-dependent protease La)
[gag-pro-pol] Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-pro (NC') (NC-pro); Protease (PR) (EC 3.4.23.-); p1; Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[gag-pro-pol] Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-pro (NC') (NC-pro); Protease (PR) (EC 3.4.23.-); p1; Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[PHEX PEX] Phosphate-regulating neutral endopeptidase PHEX (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)
[] Genome polyprotein [Cleaved into: Protein VP0 (VP4-VP2); Protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Protein VP1-2A (VP1-pX); Capsid protein VP1 (P1D) (Virion protein 1); Assembly signal 2A (pX); Protein 2BC; Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3ABCD (P3); Protein 3ABC; Protein 3AB; Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD; Protease 3C (P3C) (EC 3.4.22.28) (Picornain 3C); RNA-directed RNA polymerase 3D-POL (P3D-POL) (EC 2.7.7.48)]
[Phex Hyp Pex] Phosphate-regulating neutral endopeptidase PHEX (Metalloendopeptidase homolog PEX) (EC 3.4.24.-) (Phosphate regulating neutral endopeptidase) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[iscS iscS_1 A6581_02145 A6592_14885 A8C65_03965 A8G17_10685 A8M42_18685 A9819_14635 A9R57_16930 AC067_03015 AC789_1c28660 ACN77_09430 ACN81_26435 ACU57_06285 ACU90_01375 AJ318_26005 AKG99_22280 AM270_07100 AM446_08145 AM464_04450 AM465_11700 AMK83_11225 AML07_10540 AML35_21525 APT94_12335 APU18_00295 APZ14_05615 ARC77_08945 AU473_09315 AUQ13_13105 AUS26_21555 AW059_05940 AW106_10960 AWP75_00135 AZZ83_002723 B1K96_17760 B7C53_13290 B9M99_15840 B9N33_21250 B9T59_21105 BANRA_01075 BANRA_01250 BANRA_01564 BANRA_03228 BANRA_04417 BANRA_04547 BE963_28425 BEN53_15845 BER14_02655 BET08_22520 BH694_10200 BHF46_00575 BHS81_15460 BHS87_14335 BIQ87_14690 BIU72_16435 BIZ41_13705 BJJ90_06620 BK248_16700 BK292_20650 BK334_04895 BK373_05915 BK375_00880 BK383_22845 BK400_09035 BMT49_16180 BMT53_23050 BMT91_09840 BTQ04_10030 BTQ06_16545 BUE81_08125 BVL39_14165 BW690_04500 BWP17_17035 BZL31_13665 BZL69_10285 C1I57_24205 C2M16_05920 C2U48_21435 C4J69_10615 C4K41_12560 C4M78_10890 C5N07_10225 C5P01_05670 C5P43_04165 C5P44_15165 C6669_16070 C6986_16375 C6B13_21190 C7235_06915 C7B02_18515 C7B06_11270 C7B07_12285 C7B08_05430 CA593_14170 CCZ14_18705 CCZ17_22060 CDL37_24785 CG691_06060 CG692_02695 CG705_05185 CG706_03765 CIJ94_05825 COD30_00935 COD46_11390 CQP61_07985 CR539_17655 CRD98_15000 CRE06_08785 CRM83_27605 CRT43_15115 CRT46_15245 CSB64_12500 CT143_05820 CT146_18385 CV83915_03587 CVH05_18115 CWM24_13125 CWS33_10120 CXB56_09960 D0X26_11620 D1900_21335 D2183_14465 D2F89_15600 D3821_11555 D3I61_14705 D3Y67_12505 D4L90_10275 D5F38_15690 D6X47_12765 D7K63_08185 D7Y10_10280 D8K42_11260 D9D20_07450 D9D23_09675 D9D43_10015 D9D65_01545 D9D69_18080 D9D77_11110 D9E22_02900 D9E30_19515 D9E34_00305 D9E35_16470 D9E49_14255 D9F02_07815 D9F06_13885 D9F12_07270 D9F17_05510 D9F21_21620 D9F57_11940 D9G11_04535 D9G22_10820 D9G42_20475 D9G48_08355 D9G53_02250 D9H12_09295 D9H53_16005 D9H66_01505 D9H68_00875 D9H70_10250 D9H84_02960 D9I18_09755 D9I20_05605 D9I47_13045 D9I52_15525 D9I82_21600 D9I88_00300 D9I93_05090 D9J03_03570 D9J11_04400 D9J39_17450 D9J44_00170 D9J46_20935 D9J48_12200 D9K10_00245 D9L82_20660 D9L99_09605 DD762_08545 DIV22_32035 DL454_14365 DL545_07355 DL662_08515 DL800_19085 DL925_05730 DLU27_08960 DM129_09135 DMZ31_01825 DNQ41_17815 DNR41_15780 DNX30_07365 DOT75_08750 DP258_15600 DP277_03730 DQE83_18635 DQF57_10730 DQP22_05325 DS732_18775 DS966_02860 DTL43_01800 DTL90_08325 DTM10_01260 DTM25_14855 DTM45_09080 DU284_02515 DU290_17260 DU309_01585 DU321_15890 DU326_09650 E2855_03279 EA140_06065 EAI36_03985 EAI42_06440 EAI44_09300 EAI52_02850 EB510_14520 EB553_03505 EB569_09870 EB595_00845 EC1094V2_1138 EC3234A_44c01370 EC95NR1_01752 ECONIH1_14765 ED060_09430 ED098_13070 ED124_01250 ED287_00180 ED600_07660 ED648_04515 ED653_10050 ED658_08350 ED944_08680 EEO96_05530 EEP03_07115 EEP23_02460 EF364_02610 EFV06_05255 EGT48_08260 EGY17_01970 EIA08_10505 EIA21_07385 EL75_1117 EL79_1128 EL80_1131 ERS085365_01538 ERS085366_02045 ERS085374_00061 ERS085379_00921 ERS085383_02049 ERS085386_03188 ERS085404_01057 ERS085406_03472 ERS085411_02202 ERS085416_01266 ERS139211_00888 ERS150873_01415 ERS150876_00833 FORC28_1424 HW43_17050 JD73_17725 MJ49_18275 MS6198_28580 MS8345_02723 NCTC10090_04376 NCTC10444_01323 NCTC10766_01180 NCTC10767_02594 NCTC11181_03575 NCTC11341_00889 NCTC12950_01537 NCTC13125_04632 NCTC13462_05052 NCTC13846_01437 NCTC7152_01285 NCTC7922_00893 NCTC7927_01500 NCTC7928_01371 NCTC8009_03115 NCTC8179_04409 NCTC8196_03366 NCTC8450_04290 NCTC8500_01442 NCTC8621_01401 NCTC8959_02462 NCTC8960_04060 NCTC8985_06161 NCTC9007_03642 NCTC9036_01412 NCTC9037_01482 NCTC9045_01545 NCTC9050_04644 NCTC9055_03293 NCTC9058_00608 NCTC9062_01792 NCTC9073_04547 NCTC9075_01973 NCTC9111_01941 NCTC9119_01524 NCTC9434_01284 NCTC9701_01429 NCTC9703_01091 NCTC9706_04616 NCTC9775_05141 NCTC9777_02572 NCTC9962_00698 NCTC9969_01533 PU06_05300 RG28_09220 RK56_021935 RX35_01423 SAMEA3472033_00658 SAMEA3472044_02985 SAMEA3472047_01032 SAMEA3472055_00937 SAMEA3472056_00874 SAMEA3472070_00065 SAMEA3472080_01607 SAMEA3472090_01244 SAMEA3472108_03497 SAMEA3472110_00486 SAMEA3472112_00780 SAMEA3472114_03249 SAMEA3472147_00165 SAMEA3484427_00440 SAMEA3484429_00549 SAMEA3484433_03192 SAMEA3484434_00296 SAMEA3485101_04492 SAMEA3485113_03372 SAMEA3752372_01122 SAMEA3752557_00969 SAMEA3752559_00692 SAMEA3752620_00062 SAMEA3753064_03100 SAMEA3753097_02751 SAMEA3753164_00628 SAMEA3753290_03552 SAMEA3753300_01026 SAMEA3753397_00908 SK85_02782 SY51_14535 UC41_13245 UN91_26515 WM48_13555 WQ89_05730 WR15_01190 YDC107_1108] Cysteine desulfurase IscS (EC 2.8.1.7)
[] Endonuclease V (EC 3.2.2.17) (DNA-(apurinic or apyrimidinic site) lyase) (AP lyase) (EC 4.2.99.18) (T4 pyrimidine dimer glycosylase) (T4-Pdg)
[OMA1 MPRP1] Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog)
[OOP TOP1 At5g65620 K21L13.14] Organellar oligopeptidase A, chloroplastic/mitochondrial (EC 3.4.24.70) (Thimet metalloendopeptidase 1) (Zincin-like metalloproteases family protein 1)
[CYOP TOP2 At5g10540 F12B17.110] Probable cytosolic oligopeptidase A (EC 3.4.24.70) (Thimet metalloendopeptidase 2) (Zincin-like metalloproteases family protein 2)
[aro-1 aro-2 aro-4 aro-5 aro-9 B14H13.20 NCU016321] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.47) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]

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