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Neurochondrin

 G3R2R9_GORGO            Unreviewed;       729 AA.
G3R2R9;
16-NOV-2011, integrated into UniProtKB/TrEMBL.
16-NOV-2011, sequence version 1.
16-JAN-2019, entry version 41.
SubName: Full=Neurochondrin {ECO:0000313|Ensembl:ENSGGOP00000009530};
Gorilla gorilla gorilla (Western lowland gorilla).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Gorilla.
NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000009530, ECO:0000313|Proteomes:UP000001519};
[1] {ECO:0000313|Ensembl:ENSGGOP00000009530, ECO:0000313|Proteomes:UP000001519}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Scally A.;
"Insights into the evolution of the great apes provided by the gorilla
genome.";
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSGGOP00000009530}
IDENTIFICATION.
Ensembl;
Submitted (SEP-2011) to UniProtKB.
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EMBL; CABD030002406; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_018870726.1; XM_019015181.1.
Ensembl; ENSGGOT00000009796; ENSGGOP00000009530; ENSGGOG00000009754.
GeneID; 101147982; -.
KEGG; ggo:101147982; -.
CTD; 23154; -.
GeneTree; ENSGT00390000013601; -.
InParanoid; G3R2R9; -.
OMA; YIQATIR; -.
OrthoDB; 311670at2759; -.
TreeFam; TF323752; -.
Proteomes; UP000001519; Chromosome 1.
Bgee; ENSGGOG00000009754; Expressed in 6 organ(s), highest expression level in prefrontal cortex.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0043005; C:neuron projection; IEA:Ensembl.
GO; GO:0045453; P:bone resorption; IEA:Ensembl.
GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
InterPro; IPR016024; ARM-type_fold.
InterPro; IPR008709; Neurochondrin.
PANTHER; PTHR13109; PTHR13109; 1.
Pfam; PF05536; Neurochondrin; 1.
SUPFAM; SSF48371; SSF48371; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000001519};
Reference proteome {ECO:0000313|Proteomes:UP000001519}.
SEQUENCE 729 AA; 78894 MW; D1E9806B0152E4A4 CRC64;
MSCCDLAAAG QLGKASIMAS DCEPALNQAE GRNPTLERYL GALREAKNDS EQFAALLLVT
KAVKAGDIDA KTRRRIFDAV GFTFPNRLLT TKEAPDGCPD HVLRALGVAL LACFCSDPEL
ATHPQVLNKI PILSTFLTAR GDPDDAARRS MIDDTYQCLT AVAGTPRGPR HLIAGGTVSA
LCQAYLGHGY GFDQALALLV GLLAAAETQC WKEAEPDLLA VLRGLSEDFQ KAEDASKFEL
CQLLPLFLPP TTVPPECYRD LQAGLARILG SKLSSWQRNP ALKLAARLAH ACGSDWIPAG
SSGSKFLALL VNLACVEVRL ALEETGTEVK EDVVTACYAL MELGIQECTR CEQSLLKEPQ
KVQLVSVMKE AIGAVIHYLL QVGSEKQKEP FVFASVRILG AWLAEETSSL RKEVCQLLPF
LVRYAKTLYE EAEEANDLSQ QVANLAISPT TPGPTWPGDA LRLLLPGWCH LTVEDGPREI
LIKEGAPSLL CKYFLQQWEL TSPGHDTSVL PDSVEIGLQT CCHIFLNLVV TAPGLIKRDA
CFTSLMNTLM TSLPALVQQQ GRLLLAANVA TLGLLMARLL STSPALQGTP ASRGFFAAAI
LFLSQSHVAR ATPGSDQAVL ALSPEYEGIW ADLQELWFLG MQAFTGCVPL LPWLAPAALR
SRWPQELLQL LGSVSPNSVK PEMVAAYQGV LVELARANRL CREAMRLQAG EETASHYRMA
ALEQCLSEP


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Pathways :
WP1983: Splicing factor NOVA regulated synpatic proteins

Related Genes :
[Ncdn Kiaa0607 Sfap75] Neurochondrin (M-Sema F-associating protein of 75 kDa) (Norbin)
[NCDN KIAA0607] Neurochondrin
[Ncdn] Neurochondrin (Neurite outgrowth-related protein from the rat brain) (Norbin)
[NCDN] Neurochondrin
[Neurochondrin CG2330] Neurochondrin homolog (dNeurochondrin)
[NCDN RCJMB04_26k21] Neurochondrin
[ncdn] Neurochondrin
[Diaph1 Diap1] Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)
[MCHR1 GPR24 SLC1] Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)
[NCDN] Neurochondrin (Neurochondrin isoform 1)
[NCDN] Neurochondrin
[NCDN EGK_00545] Neurochondrin isoform 1
[NCDN CK820_G0025316] NCDN isoform 2 (NCDN isoform 3) (Neurochondrin)
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN CR201_G0015697] NCDN isoform 1 (NCDN isoform 2) (NCDN isoform 4) (Neurochondrin)
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin

Bibliography :
[29901136] Comprehensive evaluation of differential lncRNA and gene expression in patients with intervertebral disc degeneration.
[29700853] Detection of selection signatures for agonistic behaviour in cattle.
[29507115] Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology.
[29481317] A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.
[29022871] A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.
[28962041] Chorea Minor Associated with Anti-Neurochondrin Autoantibodies.
[27957508] Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration.
[27018499] Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration.
[26792863] Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
[25916936] Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein.
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