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Neurochondrin

 W5QDZ7_SHEEP            Unreviewed;       734 AA.
W5QDZ7;
16-APR-2014, integrated into UniProtKB/TrEMBL.
16-APR-2014, sequence version 1.
10-APR-2019, entry version 17.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000020945};
Name=NCDN {ECO:0000313|Ensembl:ENSOARP00000020945};
Ovis aries (Sheep).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Caprinae; Ovis.
NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020945, ECO:0000313|Proteomes:UP000002356};
[1] {ECO:0000313|Ensembl:ENSOARP00000020945, ECO:0000313|Proteomes:UP000002356}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020945};
PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
Wang J., Wang W., Xun X.;
"The sheep genome reference sequence: a work in progress.";
Anim. Genet. 41:449-453(2010).
[2] {ECO:0000313|Ensembl:ENSOARP00000020945}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2014) to UniProtKB.
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EMBL; AMGL01000789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9940.ENSOARP00000020945; -.
Ensembl; ENSOART00000021237; ENSOARP00000020945; ENSOARG00000019499.
GeneTree; ENSGT00390000013601; -.
OMA; YIQATIR; -.
Proteomes; UP000002356; Chromosome 1.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0043005; C:neuron projection; IEA:Ensembl.
GO; GO:0045453; P:bone resorption; IEA:Ensembl.
GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
InterPro; IPR008709; Neurochondrin.
PANTHER; PTHR13109; PTHR13109; 1.
Pfam; PF05536; Neurochondrin; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002356};
Reference proteome {ECO:0000313|Proteomes:UP000002356}.
SEQUENCE 734 AA; 79312 MW; 1BF978083DF47488 CRC64;
MSCCDLAAAG QLGKAGIMAS DCEPALNQAE SRNPTLERYL GALREAKNDS EQFAALLLVT
KAVKAGDIDA KTRRRIFDAV GFTFPNRLLT TKEAPDGCPD HVLRALGVAL LACFCSDPEL
AAHPQVLNKI PILSTFLTAR GDPDDAARRS MVDDTYQCLT AVAGTPRGPR HLIAGGTVSA
LCQAYLGHGY GFDQALALLV GLLAAAETQC WKEAEPDLLA VLRGLSEDFQ KAEDASKFEL
CQLLPLFLPP TTVPSECLRD LQAGLARILG SKLSSWQRNP ALKLAARLAH ACGSDWIPAG
SSGSKFLALL VNLACVEVRL ALEETGTEVK EDVVTACYAL MELGIQECTR CEQSLLKEPQ
KVQLVSIMKR GRGRAGGESR PWVGPEKQKE PFVFASVRIL GAWLAEETSS LRKEVCQLLP
FLVRYAKTLY EEAEEANDLS QQVATLAISP TTPGPTWPGD ALRLLLPGWC HLTVEDGPRE
ILIKEGAPSL LCKYFLQQWE LTSPGHDTSV LPDSVEIGLQ TCCHIFLNLV VTAPGLIKRD
ACFTSLMNTL MASLPSLVQQ QGRLLLAANV ATLGLLMARL LSTSPALQGT PASRGFFAAA
ILFLSQQPHV ARATPGSEQA VLALSPDYEG VWADLQELWF LGMQAFTGCV PLLPWLAPAA
LRSRWPQELL QLLGSVSPNS VKPEMVAAYQ GVLVELARAN RLCREAMRLQ AGEDGEETAS
HYRMAALEQC LAEP


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Pathways :
WP1983: Splicing factor NOVA regulated synpatic proteins

Related Genes :
[Ncdn Kiaa0607 Sfap75] Neurochondrin (M-Sema F-associating protein of 75 kDa) (Norbin)
[NCDN KIAA0607] Neurochondrin
[Ncdn] Neurochondrin (Neurite outgrowth-related protein from the rat brain) (Norbin)
[NCDN] Neurochondrin
[Neurochondrin CG2330] Neurochondrin homolog (dNeurochondrin)
[Diaph1 Diap1] Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)
[MCHR1 GPR24 SLC1] Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)
[NCDN RCJMB04_26k21] Neurochondrin
[ncdn] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN CK820_G0025316] NCDN isoform 2 (NCDN isoform 3) (Neurochondrin)
[NCDN EGK_00545] Neurochondrin isoform 1
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[NCDN] Neurochondrin isoform 1
[NCDN] Neurochondrin isoform 1
[NCDN] Neurochondrin
[NCDN] Neurochondrin
[Ncdn] neurochondrin isoform X1
[100815575 GLYMA_12G063700] RING-type E3 ubiquitin transferase (EC 2.3.2.27)
[Ncdn] neurochondrin isoform X3
[NCDN] neurochondrin isoform X2
[NCDN] Neurochondrin
[ncdn CR513_01230] Neurochondrin (Fragment)
[NCDN RLOC_00007800] Neurochondrin
[102591903] RING-type E3 ubiquitin transferase (EC 2.3.2.27)

Bibliography :
[31179511] Neurochondrin Antibody Serum Positivity in Three Cases of Autoimmune Cerebellar Ataxia.
[31138003] Encephalopathy Associated With Neurochondrin Autoantibodies.
[31136779] Long-term iron exposure causes widespread molecular alterations associated with memory impairment in mice.
[29901136] Comprehensive evaluation of differential lncRNA and gene expression in patients with intervertebral disc degeneration.
[29700853] Detection of selection signatures for agonistic behaviour in cattle.
[29507115] Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology.
[29481317] A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.
[29022871] A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.
[28962041] Chorea Minor Associated with Anti-Neurochondrin Autoantibodies.
[27957508] Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration.