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Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]

 ARO1_NEUCR              Reviewed;        1563 AA.
Q8X071;
05-APR-2011, integrated into UniProtKB/Swiss-Prot.
01-MAR-2002, sequence version 1.
08-MAY-2019, entry version 124.
RecName: Full=Pentafunctional AROM polypeptide {ECO:0000255|HAMAP-Rule:MF_03143};
Includes:
RecName: Full=3-dehydroquinate synthase {ECO:0000255|HAMAP-Rule:MF_03143};
Short=DHQS {ECO:0000255|HAMAP-Rule:MF_03143};
EC=4.2.3.4 {ECO:0000255|HAMAP-Rule:MF_03143};
Includes:
RecName: Full=3-phosphoshikimate 1-carboxyvinyltransferase {ECO:0000255|HAMAP-Rule:MF_03143};
EC=2.5.1.19 {ECO:0000255|HAMAP-Rule:MF_03143};
AltName: Full=5-enolpyruvylshikimate-3-phosphate synthase {ECO:0000255|HAMAP-Rule:MF_03143};
Short=EPSP synthase {ECO:0000255|HAMAP-Rule:MF_03143};
Short=EPSPS {ECO:0000255|HAMAP-Rule:MF_03143};
Includes:
RecName: Full=Shikimate kinase {ECO:0000255|HAMAP-Rule:MF_03143};
Short=SK {ECO:0000255|HAMAP-Rule:MF_03143};
EC=2.7.1.71 {ECO:0000255|HAMAP-Rule:MF_03143};
Includes:
RecName: Full=3-dehydroquinate dehydratase {ECO:0000255|HAMAP-Rule:MF_03143};
Short=3-dehydroquinase {ECO:0000255|HAMAP-Rule:MF_03143};
EC=4.2.1.10 {ECO:0000255|HAMAP-Rule:MF_03143};
Includes:
RecName: Full=Shikimate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_03143};
EC=1.1.1.25 {ECO:0000255|HAMAP-Rule:MF_03143};
Name=aro-1 {ECO:0000255|HAMAP-Rule:MF_03143};
Synonyms=aro-2, aro-4, aro-5, aro-9; ORFNames=B14H13.20, NCU016321;
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM
1257 / FGSC 987).
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae;
Neurospora.
NCBI_TaxID=367110;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
PubMed=12655011; DOI=10.1093/nar/gkg293;
Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V.,
Hoheisel J.D., Fartmann B., Nyakatura G., Kempken F., Maier J.,
Schulte U.;
"What's in the genome of a filamentous fungus? Analysis of the
Neurospora genome sequence.";
Nucleic Acids Res. 31:1944-1954(2003).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
PubMed=12712197; DOI=10.1038/nature01554;
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A.,
Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L.,
Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C.,
Marcotte E., Greenberg D., Roy A., Foley K., Naylor J.,
Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M.,
Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S.,
Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C.,
Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M.,
Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
-!- FUNCTION: The AROM polypeptide catalyzes 5 consecutive enzymatic
reactions in prechorismate polyaromatic amino acid biosynthesis.
{ECO:0000255|HAMAP-Rule:MF_03143}.
-!- CATALYTIC ACTIVITY:
Reaction=7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-
dehydroquinate + phosphate; Xref=Rhea:RHEA:21968,
ChEBI:CHEBI:32364, ChEBI:CHEBI:43474, ChEBI:CHEBI:58394;
EC=4.2.3.4; Evidence={ECO:0000255|HAMAP-Rule:MF_03143};
-!- CATALYTIC ACTIVITY:
Reaction=3-dehydroquinate = 3-dehydroshikimate + H2O;
Xref=Rhea:RHEA:21096, ChEBI:CHEBI:15377, ChEBI:CHEBI:16630,
ChEBI:CHEBI:32364; EC=4.2.1.10; Evidence={ECO:0000255|HAMAP-
Rule:MF_03143};
-!- CATALYTIC ACTIVITY:
Reaction=NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH;
Xref=Rhea:RHEA:17737, ChEBI:CHEBI:15378, ChEBI:CHEBI:16630,
ChEBI:CHEBI:36208, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349;
EC=1.1.1.25; Evidence={ECO:0000255|HAMAP-Rule:MF_03143};
-!- CATALYTIC ACTIVITY:
Reaction=ATP + shikimate = 3-phosphoshikimate + ADP + H(+);
Xref=Rhea:RHEA:13121, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
ChEBI:CHEBI:36208, ChEBI:CHEBI:145989, ChEBI:CHEBI:456216;
EC=2.7.1.71; Evidence={ECO:0000255|HAMAP-Rule:MF_03143};
-!- CATALYTIC ACTIVITY:
Reaction=3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-
carboxyvinyl)-3-phosphoshikimate + phosphate;
Xref=Rhea:RHEA:21256, ChEBI:CHEBI:43474, ChEBI:CHEBI:57701,
ChEBI:CHEBI:58702, ChEBI:CHEBI:145989; EC=2.5.1.19;
Evidence={ECO:0000255|HAMAP-Rule:MF_03143};
-!- COFACTOR:
Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
Note=Binds 2 Zn(2+) ions per subunit.;
-!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
biosynthesis; chorismate from D-erythrose 4-phosphate and
phosphoenolpyruvate: step 2/7. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
biosynthesis; chorismate from D-erythrose 4-phosphate and
phosphoenolpyruvate: step 3/7. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
biosynthesis; chorismate from D-erythrose 4-phosphate and
phosphoenolpyruvate: step 4/7. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
biosynthesis; chorismate from D-erythrose 4-phosphate and
phosphoenolpyruvate: step 5/7. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
biosynthesis; chorismate from D-erythrose 4-phosphate and
phosphoenolpyruvate: step 6/7. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SIMILARITY: In the N-terminal section; belongs to the sugar
phosphate cyclases superfamily. Dehydroquinate synthase family.
{ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SIMILARITY: In the 2nd section; belongs to the EPSP synthase
family. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SIMILARITY: In the 3rd section; belongs to the shikimate kinase
family. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SIMILARITY: In the 4th section; belongs to the type-I 3-
dehydroquinase family. {ECO:0000255|HAMAP-Rule:MF_03143}.
-!- SIMILARITY: In the C-terminal section; belongs to the shikimate
dehydrogenase family. {ECO:0000255|HAMAP-Rule:MF_03143}.
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EMBL; AL670001; CAD21207.1; -; Genomic_DNA.
EMBL; CM002237; EAA26764.1; -; Genomic_DNA.
PIR; S14749; S14749.
RefSeq; XP_956000.1; XM_950907.3.
SMR; Q8X071; -.
PRIDE; Q8X071; -.
EnsemblFungi; EAA26764; EAA26764; NCU01632.
GeneID; 3872147; -.
KEGG; ncr:NCU01632; -.
EuPathDB; FungiDB:NCU01632; -.
HOGENOM; HOG000205493; -.
InParanoid; Q8X071; -.
KO; K13830; -.
UniPathway; UPA00053; UER00085.
UniPathway; UPA00053; UER00086.
UniPathway; UPA00053; UER00087.
UniPathway; UPA00053; UER00088.
UniPathway; UPA00053; UER00089.
Proteomes; UP000001805; Chromosome 6, Linkage Group II.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:UniProtKB-UniRule.
GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:UniProtKB-UniRule.
GO; GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IBA:GO_Central.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:UniProtKB-UniRule.
GO; GO:0004765; F:shikimate kinase activity; IEA:UniProtKB-UniRule.
GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-UniRule.
GO; GO:0009423; P:chorismate biosynthetic process; IBA:GO_Central.
CDD; cd00502; DHQase_I; 1.
CDD; cd08195; DHQS; 1.
CDD; cd01556; EPSP_synthase; 1.
CDD; cd00464; SK; 1.
Gene3D; 3.20.20.70; -; 1.
Gene3D; 3.65.10.10; -; 2.
HAMAP; MF_00210; EPSP_synth; 1.
HAMAP; MF_03143; Pentafunct_AroM; 1.
HAMAP; MF_00109; Shikimate_kinase; 1.
InterPro; IPR018508; 3-dehydroquinate_DH_AS.
InterPro; IPR013785; Aldolase_TIM.
InterPro; IPR016037; DHQ_synth_AroB.
InterPro; IPR030960; DHQS/DOIS.
InterPro; IPR001381; DHquinase_I.
InterPro; IPR001986; Enolpyruvate_Tfrase_dom.
InterPro; IPR036968; Enolpyruvate_Tfrase_sf.
InterPro; IPR006264; EPSP_synthase.
InterPro; IPR023193; EPSP_synthase_CS.
InterPro; IPR036291; NAD(P)-bd_dom_sf.
InterPro; IPR027417; P-loop_NTPase.
InterPro; IPR008289; Pentafunct_AroM.
InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
InterPro; IPR031322; Shikimate/glucono_kinase.
InterPro; IPR013708; Shikimate_DH-bd_N.
InterPro; IPR010110; Shikimate_DH_AroM-type.
InterPro; IPR000623; Shikimate_kinase/TSH1.
InterPro; IPR023000; Shikimate_kinase_CS.
InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
Pfam; PF01761; DHQ_synthase; 1.
Pfam; PF01487; DHquinase_I; 1.
Pfam; PF00275; EPSP_synthase; 1.
Pfam; PF01488; Shikimate_DH; 1.
Pfam; PF08501; Shikimate_dh_N; 1.
Pfam; PF01202; SKI; 1.
PIRSF; PIRSF000514; Pentafunct_AroM; 1.
SUPFAM; SSF51735; SSF51735; 1.
SUPFAM; SSF52540; SSF52540; 1.
SUPFAM; SSF55205; SSF55205; 1.
TIGRFAMs; TIGR01356; aroA; 1.
TIGRFAMs; TIGR01357; aroB; 1.
TIGRFAMs; TIGR01093; aroD; 1.
TIGRFAMs; TIGR01809; Shik-DH-AROM; 1.
PROSITE; PS01028; DEHYDROQUINASE_I; 1.
PROSITE; PS00104; EPSP_SYNTHASE_1; 1.
PROSITE; PS00885; EPSP_SYNTHASE_2; 1.
PROSITE; PS01128; SHIKIMATE_KINASE; 1.
3: Inferred from homology;
Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
ATP-binding; Complete proteome; Cytoplasm; Kinase; Lyase;
Metal-binding; Multifunctional enzyme; NADP; Nucleotide-binding;
Oxidoreductase; Reference proteome; Transferase; Zinc.
CHAIN 1 1563 Pentafunctional AROM polypeptide.
/FTId=PRO_0000406727.
NP_BIND 48 50 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
NP_BIND 82 85 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
NP_BIND 113 115 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
NP_BIND 138 139 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
NP_BIND 178 181 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
NP_BIND 864 871 ATP. {ECO:0000255|HAMAP-Rule:MF_03143}.
REGION 1 382 3-dehydroquinate synthase.
REGION 193 196 Substrate binding 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
REGION 262 266 Substrate binding 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
REGION 395 834 EPSP synthase.
REGION 857 1051 Shikimate kinase.
REGION 1052 1265 3-dehydroquinase.
REGION 1278 1563 Shikimate dehydrogenase.
ACT_SITE 258 258 Proton acceptor; for 3-dehydroquinate
synthase activity. {ECO:0000255|HAMAP-
Rule:MF_03143}.
ACT_SITE 273 273 Proton acceptor; for 3-dehydroquinate
synthase activity. {ECO:0000255|HAMAP-
Rule:MF_03143}.
ACT_SITE 816 816 For EPSP synthase activity.
{ECO:0000255|HAMAP-Rule:MF_03143}.
ACT_SITE 1168 1168 Proton acceptor; for 3-dehydroquinate
dehydratase activity. {ECO:0000255|HAMAP-
Rule:MF_03143}.
ACT_SITE 1196 1196 Schiff-base intermediate with substrate;
for 3-dehydroquinate dehydratase
activity. {ECO:0000255|HAMAP-
Rule:MF_03143}.
METAL 193 193 Zinc; catalytic. {ECO:0000255|HAMAP-
Rule:MF_03143}.
METAL 269 269 Zinc; catalytic. {ECO:0000255|HAMAP-
Rule:MF_03143}.
METAL 285 285 Zinc; catalytic. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 118 118 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
BINDING 129 129 Substrate 1. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 145 145 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 151 151 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 160 160 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
BINDING 161 161 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 189 189 NAD. {ECO:0000255|HAMAP-Rule:MF_03143}.
BINDING 248 248 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 269 269 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 285 285 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
BINDING 354 354 Substrate 2. {ECO:0000255|HAMAP-
Rule:MF_03143}.
SEQUENCE 1563 AA; 170232 MW; 41EA4E40747C16C3 CRC64;
MAEPISNPTR INILGKDNII IDHGIWLNFV AQDLLQNIKS STYILITDTN LYKTYVPPFQ
SVFEKAAPQD VRLLTYAIPP GEYSKGRDTK AEIEDWMLSH QCTRDTVIIA LGGGVIGDMI
GYVAATFMRG VRFVQCPTTL LAMVDSSIGG KTAIDVPMGK NLIGAFWQPE RIYIDLTFLN
TLPVREFING MAEVIKTAAI WDENEFTALE ENAKAILEAV RSKNKSADRL APIRDILKRI
VLGSARVKAE VVSSDEREGG LRNLLNFGHS IGHAYEAILT PQVLHGEAVA IGMVKEAELA
RFLGVLRPSA VARLSKCIAS YDLPTSLQDK RIVKLTAGKE CPVDVLLQKM AVDKKNEGRK
KKIVLLSAIG KTYEPKASVV EDRAIRIVLS PCIRVFAGVP KDLNVSVTPP GSKSISNRAL
ILAALGEGTT RIHNLLHSDD TQVMLNAVAQ LQGASFSWEE GDVLVVKGNG GKLQATSTPL
YLGNAGTASR FLTSVAALCN PSDVNSTVLT GNARMKQRPI GALVDALRAN GVGVKYLEKE
HSLPVQVDAA GGLAGGVMEL AATISSQYVS SLLMAAPYAR EPVTLRLVGG KPISQPYIDM
TIAMMASFGV QVQRSAEDPN TYYIPQGTYK NPETYVVESD ASSATYPLAI AAITGTTCTV
PNIGSKSLQG DARFAIEVLR PMGCTVEQTD VSTTVTGPPI GTLKAIPHVD MEPMTDAFLT
ASVLAAVASG TTQITGIANQ RVKECNRILA MKDQLAKFGV HCNELEDGIE VIGIPYTELK
NPTEGIYCYD DHRVAMSFSV LSTISPHPVL ILERECTGKT WPGWWDTMSN YFKVHLEGEE
EPHSSHVSHE KPRKGNPKSI FIIGMRGAGK STAGKWMSEV LNRPLIDLDH ELERREGQTI
PEIIRSERGW EGFRKAELEL LEDVIKNNPT GHIFSCGGGI VETEAARKML LSYSQNGGIV
LLVHRDTDQV VEYLMRDKSR PAYSENIREV YYRRKPFFEE CSNFRYYSPH PDGSKALTEP
PFDFSQFLSV ICGHSNHLEE VKKKPHSFFV SLTVPNVSKA LDIIPKVVVG SDAVELRVDL
LEDYDPEFVA KQVALLRSAA RIPIVYTVRT VSQGGKFPDD DYELALKLYR TGLQAGVEYL
DLEMTMPDEV IEAVTNEKGY THIIASHHDP KATLSWKNGG WIQYYNKALQ HGDVVKLVGV
ARELADNFAL ARFKASLAAA HDKPLIALNM GAAGKLSRVL NGFLTPVSHP ALPSKAAPGQ
LSAAEIRQAL ALIGELEPRS FHLFGNPISA SRSPALHNAL FRDNGLPHQY SLFETDNAAD
VKDLIRAPGF GGASVTIPLK LDIMPLLDEV SDAAKVIGAV NTIIPVRNGD KVTLRGDNTD
WMGMVYALRN AGVVKCTKES PTAGMVVGAG GTTRAAVHAL HDLGFAPIYV VARNADRVKA
LAESFPAEYD IRSLSTPEEV AAESTAQPSV VISTIPADKP IDQSMREVIV ASLRHPSVAD
GKHVLLEMAY TPRHTPLMQL AEDAHWQTIP GLEVLAAQGW YQFQLWTGIT PIYTDAQAAV
MGN


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E0167r ELISA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
E0167b ELISA Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
E0167b ELISA kit Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
E0167m ELISA kit Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,L-PGDS,Mouse,Mus musculus,PGD2 synthase,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds 96T
E0167r ELISA kit Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
U0167b CLIA Bos taurus,Bovine,Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS 96T
U0167r CLIA Glutathione-independent PGD synthase,Lipocalin-type prostaglandin-D synthase,PGD2 synthase,PGDS,PGDS2,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,Ptgds,Rat,Rattus norvegicus 96T
Pathways :
WP2341: vitamin B1 (thiamin) biosynthesis and salvage pathway
WP2340: Thiamine (vitamin B1) biosynthesis and salvage
WP296: TCA Cycle - biocyc
WP1621: Arginine and proline metabolism
WP1423: Ganglio Sphingolipid Metabolism
WP2199: Seed Development
WP2210: Oryzalexin S biosynthesis
WP1493: Carbon assimilation C4 pathway
WP2248: anthocyanin biosynthesis
WP677: Momilactone biosynthesis
WP1422: Sphingolipid Metabolism
WP2208: Cardiolipin Biosynthesis
WP1461: Photosynthetic Carbon Reduction
WP253: Glycolysis
WP1403: AMPK signaling
WP1424: Globo Sphingolipid Metabolism
WP2211: Geranylgeranyldiphosphate biosynthesis II (plastidic)
WP1708: Terpenoid backbone biosynthesis
WP626: Abscisic Acid Biosynthesis
WP668: Octadecanoid Pathway
WP312: Pentose Phosphate Pathway
WP1703: Streptomycin biosynthesis
WP1567: Glycolysis and Gluconeogenesis
WP575: Anaerobic respiration
WP1657: Glycerolipid metabolism

Related Genes :
[aro-1 aro-2 aro-4 aro-5 aro-9 B14H13.20 NCU016321] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[RPS0 BST61_czeina10g000760] Multifunctional fusion protein [Includes: Pentafunctional AROM polypeptide; 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25); 40S ribosomal protein S0]
[K503DRAFT_817084] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[AZE42_04798] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[ARO1 AWRI1499_0380] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[ARO1 AWRI3578_g3716] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[hchA A8C65_13880 A9R57_25255 AKG99_20940 AMK83_16550 B7C53_22525 B9M99_11580 B9T59_01945 BJJ90_15205 BMT49_12710 BMT53_00170 BUE81_10670 BW690_17225 BZL69_29425 C2U48_24800 C5715_19445 C5N07_21380 C6669_19295 C7B06_02290 C7B07_03930 CDL37_00765 CG691_19145 CG705_13560 CG706_14580 CIJ94_05515 COD46_23180 CQP61_17160 CRD98_26150 CY655_12940 D5618_21870 D8K42_21280 D8Y29_11125 D9D20_21030 D9D43_06110 D9E22_21005 D9H68_20750 D9H70_25730 D9I87_15275 DL800_09215 DNQ41_14245 DQE83_22775 DTL43_21780 DTM25_06080 DU321_04440 E2855_02503 E2863_02392 EC95NR1_00961 ED648_25045 EFV01_02465 EFV04_09725 EOL36_23890 ERS085379_01273 ERS085386_05041 HMPREF3040_01583 HW43_13705 NCTC10082_04431 NCTC10418_03071 NCTC10767_03558 NCTC11022_01867 NCTC11126_04427 NCTC11181_05650 NCTC12950_02263 NCTC13462_05714 NCTC8985_00529 NCTC9111_05933 NCTC9112_02079 NCTC9703_00277 PU06_24500 SAMEA3472043_00447 SAMEA3472055_03589 SAMEA3472056_01268 SAMEA3472070_00654 SAMEA3472080_04213 SAMEA3472090_03376 SAMEA3472110_00060 SAMEA3472112_00448 SAMEA3752372_00752 UN91_23615 WQ89_10695] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[aroA SP_1371] 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)
[hchA A9819_11910 ACN81_03425 AML35_08765 AW059_23935 BANRA_00208 BANRA_00433 BANRA_02614 BHF46_18455 BMT91_24760 C4J69_22715 C7B08_25495 CR538_10415 D2F89_25795 D3Y67_22910 D9G42_11130 D9I97_22010 D9J11_25195 DP258_02540 EC3234A_36c00010 EC382_21100 ECTO6_01955 EFV06_13085 EFV16_12340 NCTC8500_02249 NCTC9037_02122 NCTC9117_02637 NCTC9969_02156 SAMEA3472108_01151 SAMEA3484427_04795 SAMEA3484429_02051 SAMEA3752557_05476 SAMEA3752559_04333] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[pyrG A6592_02570 A8M42_16405 A9R57_06965 AC067_22330 AC789_1c31020 ACN002_2797 ACN77_07080 ACN81_20385 ACU57_24415 ACU90_23015 AJ318_22735 AKG99_03555 AM270_00945 AM446_06950 AM464_05605 AM465_10605 AML07_12460 AML35_05300 APT94_17890 APU18_18535 APZ14_09290 ARC77_10140 AU473_08010 AUQ13_17535 AUS26_15660 AW059_10675 AW106_00665 AWE53_025360 AWF23_022760 AWF59_014510 AWF80_016095 AWG78_018325 AWP75_20610 AZZ83_003241 B1K96_20050 B7C53_10055 B9M99_21725 B9N33_09475 B9T59_19685 BANRA_01301 BANRA_01853 BANRA_03509 BANRA_03630 BANRA_04184 BANRA_04324 BB545_13920 BE963_03670 BEN53_16995 BET08_07180 BFD68_17190 BHF46_05050 BHS81_16640 BHS87_15735 BIQ87_15835 BIU72_09520 BIZ41_16885 BJJ90_05265 BK248_12970 BK292_23205 BK334_11935 BK373_15870 BK375_10085 BK383_11680 BK400_05820 BMT49_17330 BMT53_21250 BMT91_11105 BN17_26661 BTQ04_11510 BTQ06_23845 BUE81_06975 BVL39_12970 BW690_04975 BWP17_05185 BXT93_24405 BZL31_00820 BZL69_02125 C1I57_04860 C2M16_17770 C2U48_20025 C3449_06035 C4J69_11655 C4K41_05275 C4M78_00835 C5715_23540 C5N07_06155 C5P01_05005 C5P43_15935 C5P44_09340 C6669_14670 C6986_17750 C6B13_03370 C7235_05745 C7B02_19400 C7B06_11630 C7B07_14530 C7B08_01430 C9E25_03325 CA593_12975 CCZ14_04445 CCZ17_10850 CDL37_13440 CG691_07365 CG692_07005 CG705_05530 CG706_07860 CIJ94_12220 COD30_01795 COD46_07095 CQP61_06810 CR538_05495 CR539_18815 CRE06_03485 CRM83_26360 CRT43_16405 CRT46_16440 CSB64_15850 CT143_09630 CT146_00680 CV83915_03339 CVH05_06295 CWM24_00790 CWS33_03125 CY655_17835 D0X26_06660 D1900_12730 D2183_19100 D2184_01135 D2185_02785 D2F89_14380 D3821_11140 D3O91_13425 D3Y67_06430 D4M06_10805 D6X47_20010 D7K63_03745 D7K66_09735 D7Y10_03025 D8Y29_15815 D9D20_04450 D9D33_19300 D9D43_17525 D9E22_07155 D9E35_20180 D9F17_11720 D9F57_14060 D9G11_10545 D9G42_05640 D9G48_11875 D9H53_12755 D9H68_17340 D9H70_12195 D9H94_16855 D9I18_10690 D9I20_00375 D9I47_00795 D9I87_07250 D9I88_14405 D9I97_09750 D9J03_22055 D9J11_17735 D9J44_16360 D9J46_14445 D9J60_10045 D9L89_10810 D9L99_02095 D9N32_10755 D9X97_06540 DD762_13665 DIV22_29760 DL455_11645 DL545_05995 DL800_20505 DM129_10705 DMI04_14240 DMZ31_10015 DNB37_12630 DNQ41_18960 DNR41_08670 DNX30_08935 DOY56_02000 DP258_16075 DP277_11440 DQE83_04685 DQO13_13250 DS732_20695 DS966_06010 DTL43_09355 DTL90_02675 DTM10_03745 DTM25_22630 DTM45_13530 DU310_11875 DU321_06150 DU333_12515 DW236_13020 DWB25_05920 E2855_03617 E2863_03463 EAI42_07155 EAI44_18400 EAI46_14335 EAI52_12500 EB509_19080 EB510_16355 EB515_03490 EC1094V2_904 EC1639_03756 EC3234A_48c00890 EC3426_03921 EC382_15705 EC95NR1_02021 Eco118UI_16400 ECONIH1_15890 ECs3640 ECTO124_01152 ECTO6_01068 ED225_00710 ED287_02625 ED600_14885 ED607_09825 ED611_00710 ED648_01520 ED903_09700 ED944_03505 EEA45_12675 EEP23_14050 EF173_03685 EFV01_14240 EFV02_06000 EFV04_18080 EFV06_07140 EFV08_05820 EFV11_00435 EFV12_15800 EFV14_04015 EFV15_05815 EFV16_07830 EFV17_00480 EGT48_09620 EGY17_03100 EIA08_07275 EIA13_21160 EIA21_04795 EJH97_05405 EL75_0914 EL79_0915 EL80_0918 EOL36_05365 ERS085365_02427 ERS085366_03042 ERS085374_03279 ERS085386_03410 ERS085416_02898 ERS139211_02072 ERS150873_02003 ERS150876_01467 FORC28_1110 GJ11_18025 HMPREF3040_01161 HW43_18180 JD73_16335 MJ49_17095 MS6198_30910 MS8345_02965 NCTC10082_03473 NCTC10090_04050 NCTC10418_01701 NCTC10444_01093 NCTC10764_00296 NCTC10766_00690 NCTC10767_02309 NCTC11022_02860 NCTC11112_00121 NCTC11181_03277 NCTC12950_01251 NCTC13125_04353 NCTC13127_01436 NCTC13462_04807 NCTC13846_01212 NCTC7927_01209 NCTC8500_01090 NCTC8960_03783 NCTC9007_03892 NCTC9036_01135 NCTC9037_01243 NCTC9044_00576 NCTC9045_01221 NCTC9050_04166 NCTC9058_00847 NCTC9062_02131 NCTC9075_01630 NCTC9077_01409 NCTC9081_05851 NCTC9112_01131 NCTC9117_01609 NCTC9119_01271 NCTC9434_01004 NCTC9702_01298 NCTC9706_03296 NCTC9775_04845 NCTC9777_02704 NCTC9969_01292 PU06_02080 RG28_07675 RK56_023165 SAMEA3472033_01264 SAMEA3472043_01265 SAMEA3472044_02272 SAMEA3472047_00339 SAMEA3472056_05455 SAMEA3472070_01673 SAMEA3472080_03155 SAMEA3472090_00131 SAMEA3472108_00527 SAMEA3472110_03462 SAMEA3472112_03722 SAMEA3472114_02432 SAMEA3472147_03296 SAMEA3484427_03298 SAMEA3484429_03415 SAMEA3484434_01581 SAMEA3485101_02257 SAMEA3485113_02257 SAMEA3752372_03639 SAMEA3752553_01510 SAMEA3752557_03040 SAMEA3752559_02995 SAMEA3752620_01282 SAMEA3753064_02287 SAMEA3753097_02219 SAMEA3753164_01192 SAMEA3753290_02847 SAMEA3753300_01107 SK85_03024 SY51_15605 UC41_20365 UN91_03645 WQ89_10170 WR15_06090 YDC107_1339] CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)
[] Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM (Precursor membrane protein); Peptide pr (Peptide precursor); Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[hmpA hmp A8C65_03855 A9R57_17040 ACN002_2592 ACN77_09545 ACN81_26320 ACU57_10360 ACU90_01485 AM270_07210 AM464_04560 AML07_10430 APZ14_05505 AUQ13_13215 AUS26_21665 AW106_11070 AWF80_015090 BANRA_01097 BANRA_03418 BANRA_04525 BB545_05760 BHS81_15570 BHS87_14445 BJJ90_06510 BK292_20760 BMT53_22940 BMT91_09730 BN17_18391 BUE81_08005 BVL39_14050 BW690_11150 BZL31_13550 C2U48_21325 C4J69_10505 C5N07_10115 C5P01_05560 C5P43_25010 C6986_16510 C7235_06805 C9E25_16695 CG691_06165 CG705_05290 CG706_03875 COD30_01045 COD46_11500 CRM83_27495 CWS33_10010 D2184_18725 D2185_06690 D3821_11445 D3O91_03570 D3Y67_23905 D9E22_02790 D9F57_20505 D9H68_00985 D9I18_09865 D9I97_07905 D9J11_04290 D9J44_00060 DIV22_11300 DL545_07245 DL800_19195 DMZ31_01715 DNQ41_17925 DP277_03620 DTL43_01910 E2855_03303 E2863_03210 EAI42_06330 EAI44_09410 EC1094V2_1116 EC3234A_44c01590 EC95NR1_01777 ECTO6_01279 ED600_07770 EEP23_02350 EFV01_13935 EFV02_11870 EFV04_05815 EFV08_03440 EFV11_08940 EFV12_11800 EFV15_03135 ERS085365_01518 ERS085374_00038 ERS085416_03760 ERS139211_00868 ERS150873_01392 ERS150876_00857 FORC28_1400 HW43_17160 NCTC11022_02631 NCTC11181_03552 NCTC13148_02382 NCTC8500_01411 NCTC8960_04037 NCTC8985_06124 NCTC9036_01390 NCTC9037_01459 NCTC9058_00631 NCTC9062_01812 NCTC9073_04581 NCTC9706_04593 NCTC9962_00729 PU06_05410 RG28_09110 RK56_022045 SAMEA3446340_03873 SAMEA3472043_01058 SAMEA3472044_03009 SAMEA3472070_00042 SAMEA3472080_01630 SAMEA3484427_00463 SAMEA3484429_00572 SAMEA3752553_02327 SAMEA3752557_00946 SAMEA3753097_02775 SK85_02808 WQ89_05840] Flavohemoprotein (Flavohemoglobin) (Hemoglobin-like protein) (Nitric oxide dioxygenase) (NO oxygenase) (NOD) (EC 1.14.12.17)
[1a] Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO) (SARS coronavirus main proteinase); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]
[aroK aroB DZB54_10170] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[lon lon_1 lon_2 lon_3 A6581_06540 A8C65_09155 A8G17_09470 A8M42_12205 A9819_02150 A9R57_08730 AC067_13940 AC789_1c04390 ACN77_08400 ACN81_24745 ACU57_11790 ACU90_20700 AJ318_07395 AM270_02090 AM446_21265 AM464_19190 AM465_24425 AMK83_09080 AML07_05605 AML35_17195 APT94_11405 APU18_24755 APZ14_19130 AUQ13_18305 AUS26_08525 AW059_13755 AW106_10030 AWE53_023455 AWF23_009230 AWF59_002015 AWF80_027560 AWG78_005680 AWP75_24635 AZZ83_000203 B1K96_09680 B7C53_07945 B9M99_03985 B9N33_08900 B9T59_05700 BANRA_00867 BANRA_00977 BANRA_01969 BANRA_02043 BANRA_03641 BANRA_04310 BB545_15795 BE963_16350 BER14_14325 BET08_18215 BFD68_17910 BHF46_21220 BHS81_02650 BIQ87_02425 BIU72_03070 BIZ41_19875 BJJ90_20055 BK248_01840 BK292_14395 BK334_05695 BK373_01080 BK375_01675 BK383_14710 BK400_22925 BMT49_03495 BMT53_08160 BMT91_05050 BN17_02431 BTQ06_01040 BUE81_06550 BVL39_00620 BW690_06825 BXT93_14065 BZL31_10455 BZL69_16545 C1I57_02830 C2M16_02950 C3449_08060 C4J69_09250 C4M78_17970 C5715_07650 C5N07_12995 C5P01_16055 C5P43_02540 C6669_02490 C6986_02640 C6B13_10210 C7235_18620 C7B06_13115 C7B07_14925 C7B08_06455 C9E25_04330 CA593_00935 CCZ14_02195 CCZ17_03875 CDL37_08925 CG692_04795 CG705_03025 CG706_02860 CIJ94_10835 COD30_15795 COD46_04600 CQP61_20635 CR538_19245 CR539_06435 CRD98_01930 CRT43_02425 CRT46_02355 CSB64_03555 CT143_00390 CT146_15985 CWM24_20160 CWS33_13550 CY655_02360 D0X26_07675 D1900_17610 D2183_00880 D2184_11270 D2185_12310 D2F89_19370 D3821_12655 D3O91_18250 D3Y67_14595 D5618_15420 D6X47_16730 D7Y10_06170 D8K42_15275 D8Y29_02110 D9D20_11240 D9D31_04875 D9D33_05815 D9D43_21565 D9E22_05125 D9E34_09980 D9E35_07020 D9E49_06700 D9F17_03270 D9F57_07485 D9G11_06315 D9H53_20830 D9H94_07265 D9I18_05150 D9I20_07000 D9I47_07695 D9I87_03565 D9I88_11055 D9J03_07390 D9J11_02395 D9J44_06085 D9J46_04320 D9J60_08825 D9L99_04615 D9N32_22800 DD762_17560 DIV22_26545 DL545_18880 DL800_04145 DM129_08665 DMZ31_12720 DNQ41_06120 DNQ45_04780 DNX30_05000 DP258_04840 DP277_07795 DQE83_14690 DQF57_07925 DQO13_05765 DS732_07170 DS966_18225 DTL43_07145 DTM10_06325 DTM25_22445 DTM45_11225 DU310_22610 DU321_07375 DU333_14745 DWB25_18925 E2855_00491 E2863_00475 EAI42_06530 EAI44_11230 EAI46_00915 EAI52_03190 EC1094V2_3409 EC1639_01225 EC3234A_4c01080 EC3426_01277 EC382_09250 EC95NR1_04662 Eco118UI_02490 ECONIH1_02385 ECTO124_03769 ECTO6_03661 ED287_10370 ED600_06055 ED648_01980 EEP23_01295 EFV01_15865 EFV02_00950 EFV04_09045 EFV06_11505 EFV11_06915 EFV12_04345 EFV14_05420 EFV16_10770 EFV17_08075 EGT48_21635 EGY17_15430 EIA08_09740 EIA13_09900 EJH97_18300 EOL36_01200 EPS76_04560 ERS085365_02395 ERS085374_02327 ERS085379_01165 ERS085383_00971 ERS085406_02176 ERS085416_01921 ERS139211_01924 ERS150876_00617 FORC28_4645 GJ11_02625 HMPREF3040_03444 HW43_05825 MJ49_04235 MS6198_04430 MS8345_00443 NCTC10082_01029 NCTC10090_01830 NCTC10418_05598 NCTC10764_05303 NCTC10766_05771 NCTC11022_05186 NCTC11181_01095 NCTC13462_01885 NCTC13846_03631 NCTC7922_06176 NCTC7927_04214 NCTC7928_04997 NCTC8179_01705 NCTC8196_01204 NCTC8959_05066 NCTC8960_01264 NCTC9007_00214 NCTC9036_03791 NCTC9037_03909 NCTC9050_01704 NCTC9055_00655 NCTC9058_03169 NCTC9062_04515 NCTC9111_03927 NCTC9117_04741 NCTC9434_02860 NCTC9703_03170 NCTC9706_01065 NCTC9777_00122 NCTC9969_03979 PU06_02695 RG28_02630 RK56_026450 RX35_02110 SAMEA3472033_03457 SAMEA3472043_02729 SAMEA3472044_00416 SAMEA3472047_02150 SAMEA3472055_02113 SAMEA3472070_02234 SAMEA3472080_01763 SAMEA3472090_01765 SAMEA3472108_01909 SAMEA3472110_00680 SAMEA3472112_02916 SAMEA3484427_03496 SAMEA3484429_01936 SAMEA3485113_01252 SAMEA3752372_02700 SAMEA3752553_00236 SAMEA3752557_00263 SAMEA3752559_02850 SAMEA3752620_00833 SAMEA3753097_00463 SAMEA3753164_00266 SAMEA3753300_00505 SK85_00464 SY51_02300 UC41_11885 UN86_09160 UN91_18465 WR15_04115 YDC107_3709] Lon protease (EC 3.4.21.53) (ATP-dependent protease La)
[aroB aroK BKH12_01900] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroA aroB SAMN02745691_00772] Multifunctional fusion protein [Includes: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroB aroA SAMEA3545249_00728] Multifunctional fusion protein [Includes: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroB aroA SAMEA3545263_00511] Multifunctional fusion protein [Includes: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[aroK aroB AUI83_27450] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroK aroB DD235_13480] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[yjbN dus_1 dusA A6581_03815 A9819_23140 AC789_1c44580 ACN77_13265 ACN81_05795 AW059_18320 AWF80_023240 B1K96_03640 B7C53_20030 B9M99_07285 B9T59_11200 BANRA_00006 BANRA_02728 BANRA_02889 BANRA_03307 BANRA_05130 BB545_04715 BE963_11655 BHS81_24320 BIU72_20630 BN17_40231 BTQ06_28285 BUE81_22495 BVL39_04970 BWP17_09085 BXT93_20165 BZL69_05000 C2U48_12360 C4J69_17345 C4M78_06330 C5N07_20225 C5P01_10975 C5P43_26750 C6669_07250 C7235_23350 C7B02_13830 CA593_05650 CG691_24515 CG705_24980 CG706_06955 CIJ94_13445 COD46_18670 CQP61_25690 CR538_23810 CRD98_24950 CRM83_18265 CVH05_02240 CWS33_16005 CY655_25665 D0X26_12230 D3821_04670 D3822_08770 D5618_12235 D6X47_24985 D7K63_02810 D8K42_02240 D8Y29_22820 D9D31_22380 D9E34_02100 D9G11_16395 D9I88_03920 D9I97_23040 D9J03_04435 D9J44_17705 DD762_09595 DL545_23295 DMZ31_05365 DNQ41_01750 DP277_17700 DQE83_12890 DQF57_12565 DQO13_07475 DS732_01940 DU310_10975 DU321_20725 EAI42_11800 EAI46_13935 EB510_19460 EC1639_00374 EC3234A_77c00420 EC3426_00373 Eco118UI_23990 ED287_08370 EEP23_23845 EF173_02750 EFV02_20690 EFV04_19480 EFV06_17385 EFV11_14225 EFV12_14460 EFV14_16985 EFV16_16620 EFV17_15560 EJH97_22895 EL75_4140 EL79_4345 EL80_4252 EOL36_08950 ERS085374_01630 ERS085383_01453 ERS085404_01248 HMPREF3040_01367 NCTC10090_02700 NCTC10418_07037 NCTC10764_02883 NCTC10865_05778 NCTC11112_02403 NCTC11181_01881 NCTC11341_02874 NCTC12950_05132 NCTC7927_05171 NCTC8450_00470 NCTC8985_03929 NCTC9037_04708 NCTC9044_02384 NCTC9045_05465 NCTC9050_02741 NCTC9062_03523 NCTC9077_05824 NCTC9701_04921 NCTC9702_05560 NCTC9775_03044 NCTC9777_01046 RK56_017030 RX35_03830 SAMEA3446340_04610 SAMEA3472055_01598 SAMEA3472108_01690 SAMEA3472114_02034 SAMEA3472147_04808 SAMEA3484427_03836 SAMEA3484429_02481 SAMEA3752553_02493 SAMEA3752559_00279 SAMEA3753064_01454 SAMEA3753290_01943 SAMEA3753300_00780] tRNA-dihydrouridine(20/20a) synthase (EC 1.3.1.-) (EC 1.3.1.91) (U20-specific dihydrouridine synthase) (U20-specific Dus) (tRNA-dihydrouridine synthase A)
[aroB aroK CO094_10075] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroK aroB ASR47_1002175] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroK aroB ADN00_02480] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroB aroK AUG45_00530] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroB aroK SAMN05880566_101498] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]
[aroB aroK CTY31_04825] Multifunctional fusion protein [Includes: Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4)]

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