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Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)

 DEOB_GEOSE              Reviewed;         393 AA.
O24821;
28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
08-MAY-2019, entry version 89.
RecName: Full=Phosphopentomutase {ECO:0000255|HAMAP-Rule:MF_00740};
EC=5.4.2.7 {ECO:0000255|HAMAP-Rule:MF_00740};
AltName: Full=Phosphodeoxyribomutase {ECO:0000255|HAMAP-Rule:MF_00740};
Name=deoB {ECO:0000255|HAMAP-Rule:MF_00740}; Synonyms=ppm;
Geobacillus stearothermophilus (Bacillus stearothermophilus).
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
NCBI_TaxID=1422;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=TH 6-2;
PubMed=9692190; DOI=10.1271/bbb.62.1103;
Hamamoto T., Noguchi T., Midorikawa Y.;
"Phosphopentomutase of Bacillus stearothermophilus TH6-2: the enzyme
and its gene ppm.";
Biosci. Biotechnol. Biochem. 62:1103-1108(1998).
-!- FUNCTION: Phosphotransfer between the C1 and C5 carbon atoms of
pentose. {ECO:0000255|HAMAP-Rule:MF_00740}.
-!- CATALYTIC ACTIVITY:
Reaction=alpha-D-ribose 1-phosphate = D-ribose 5-phosphate;
Xref=Rhea:RHEA:18793, ChEBI:CHEBI:57720, ChEBI:CHEBI:78346;
EC=5.4.2.7; Evidence={ECO:0000255|HAMAP-Rule:MF_00740};
-!- CATALYTIC ACTIVITY:
Reaction=2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-
phosphate; Xref=Rhea:RHEA:27658, ChEBI:CHEBI:57259,
ChEBI:CHEBI:62877; EC=5.4.2.7; Evidence={ECO:0000255|HAMAP-
Rule:MF_00740};
-!- COFACTOR:
Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
Evidence={ECO:0000255|HAMAP-Rule:MF_00740};
Note=Binds 1 or 2 manganese ions. {ECO:0000255|HAMAP-
Rule:MF_00740};
-!- PATHWAY: Metabolic intermediate biosynthesis; 5-phospho-alpha-D-
ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-
diphosphate from D-ribose 5-phosphate (route II): step 1/3.
{ECO:0000255|HAMAP-Rule:MF_00740}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00740}.
-!- SIMILARITY: Belongs to the phosphopentomutase family.
{ECO:0000255|HAMAP-Rule:MF_00740}.
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EMBL; AB008120; BAA22917.1; -; Genomic_DNA.
PIR; JE0180; JE0180.
SMR; O24821; -.
UniPathway; UPA00087; UER00173.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-UniRule.
GO; GO:0008973; F:phosphopentomutase activity; IEA:UniProtKB-UniRule.
GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
GO; GO:0043094; P:cellular metabolic compound salvage; IEA:InterPro.
GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:UniProtKB-UniRule.
CDD; cd16009; PPM; 1.
Gene3D; 3.30.70.1250; -; 1.
Gene3D; 3.40.720.10; -; 1.
HAMAP; MF_00740; Phosphopentomut; 1.
InterPro; IPR017850; Alkaline_phosphatase_core_sf.
InterPro; IPR010045; DeoB.
InterPro; IPR006124; Metalloenzyme.
InterPro; IPR024052; Phosphopentomutase_DeoB_cap_sf.
PANTHER; PTHR21110; PTHR21110; 1.
Pfam; PF01676; Metalloenzyme; 1.
PIRSF; PIRSF001491; Ppentomutase; 1.
SUPFAM; SSF143856; SSF143856; 1.
SUPFAM; SSF53649; SSF53649; 1.
TIGRFAMs; TIGR01696; deoB; 1.
3: Inferred from homology;
Cytoplasm; Isomerase; Manganese; Metal-binding.
CHAIN 1 393 Phosphopentomutase.
/FTId=PRO_0000199809.
METAL 14 14 Manganese. {ECO:0000255|HAMAP-
Rule:MF_00740}.
METAL 292 292 Manganese. {ECO:0000255|HAMAP-
Rule:MF_00740}.
METAL 328 328 Manganese. {ECO:0000255|HAMAP-
Rule:MF_00740}.
METAL 329 329 Manganese. {ECO:0000255|HAMAP-
Rule:MF_00740}.
METAL 340 340 Manganese. {ECO:0000255|HAMAP-
Rule:MF_00740}.
SEQUENCE 393 AA; 43736 MW; 4D739006C37BCEE8 CRC64;
MKPTCKRVFL IVMDSVGIGE APDAEKYNDK GADTLGHIAE HRGGLNMPNM AKLGLSNIRE
IEGIPKAEKP LAYYTKMQEA SAGKDTMTGH WELMGLRIDT PFQVFPDGFP KELIDELEKQ
TGRKVIGNKP ASGTAIIDEL GPEHMETGAL IVYTSADSVL QIAAHEEVIP LEELYRICKI
ARELTLDEKY MVGRVIARPF IGTPGNFQRT ANRHDYALKP FGRTVMNELQ DAGYDVIAIG
KIADIYDNEG VTKTLRTKSN MDGMDKLVNT LQMNFTGLSF LNLVDFDALY GHRRDPKGYG
DALEEFDARL PEVFERLKED DLLIITADHG NDPVHHGTDH TREYVPLLVY SPSMNGGKQL
PLRETFADVG ATIAENFGVK MPKYGTSFLQ ELK


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[miaA deoB DMF77_21325] Multifunctional fusion protein [Includes: tRNA dimethylallyltransferase (EC 2.5.1.75) (Dimethylallyl diphosphate:tRNA dimethylallyltransferase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (DMAPP:tRNA dimethylallyltransferase) (DMATase) (IPP transferase) (IPPT) (IPTase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoC deoB SAMN05216413_2295] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoB deoC SAMN06296952_0813] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoB drm thyR b4383 JW4346] Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)
[deoB deoC SAMN02910456_01831] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoB deoC SAMN06297423_1997] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoB deoC B0O40_1997] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoB deoC SAMN02910264_00675] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[deoC deoB] Multifunctional fusion protein [Includes: Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)]
[cdiA4 cdiA-CTo11 ECH7EC869_5883] Deoxyribonuclease CdiA-o11 (DNase CdiA) (EC 3.1.-.-) (CdiA-o11-EC869) (Toxin CdiA)
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[hchA A9819_11910 ACN81_03425 AML35_08765 AW059_23935 BANRA_00208 BANRA_00433 BANRA_02614 BHF46_18455 BMT91_24760 C4J69_22715 C7B08_25495 CR538_10415 D2F89_25795 D3Y67_22910 D9G42_11130 D9I97_22010 D9J11_25195 DP258_02540 EC3234A_36c00010 EC382_21100 ECTO6_01955 EFV06_13085 EFV16_12340 NCTC8500_02249 NCTC9037_02122 NCTC9117_02637 NCTC9969_02156 SAMEA3472108_01151 SAMEA3484427_04795 SAMEA3484429_02051 SAMEA3752557_05476 SAMEA3752559_04333] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[] Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM (Precursor membrane protein); Peptide pr (Peptide precursor); Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[hchA ECH7EC869_3386] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[hchA ECH74115_2746] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[deoB ECH74115_5898] Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)
[] Endonuclease V (EC 3.2.2.17) (DNA-(apurinic or apyrimidinic site) lyase) (AP lyase) (EC 4.2.99.18) (T4 pyrimidine dimer glycosylase) (T4-Pdg)
[] Genome polyprotein [Cleaved into: N-terminal protease (N-pro) (EC 3.4.22.-) (Autoprotease p20); Capsid protein C; E(rns) glycoprotein (gp44/48); Envelope glycoprotein E1 (gp33); Envelope glycoprotein E2 (gp55); p7; Non-structural protein 2-3; Cysteine protease NS2 (EC 3.4.22.-) (Non-structural protein 2); Serine protease NS3 (EC 3.4.21.113) (EC 3.6.1.15) (EC 3.6.4.13) (Non-structural protein 3); Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); Non-structural protein 5A (NS5A); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5B)]
[pyrG A6592_02570 A8M42_16405 A9R57_06965 AC067_22330 AC789_1c31020 ACN002_2797 ACN77_07080 ACN81_20385 ACU57_24415 ACU90_23015 AJ318_22735 AKG99_03555 AM270_00945 AM446_06950 AM464_05605 AM465_10605 AML07_12460 AML35_05300 APT94_17890 APU18_18535 APZ14_09290 ARC77_10140 AU473_08010 AUQ13_17535 AUS26_15660 AW059_10675 AW106_00665 AWE53_025360 AWF23_022760 AWF59_014510 AWF80_016095 AWG78_018325 AWP75_20610 AZZ83_003241 B1K96_20050 B7C53_10055 B9M99_21725 B9N33_09475 B9T59_19685 BANRA_01301 BANRA_01853 BANRA_03509 BANRA_03630 BANRA_04184 BANRA_04324 BB545_13920 BE963_03670 BEN53_16995 BET08_07180 BFD68_17190 BHF46_05050 BHS81_16640 BHS87_15735 BIQ87_15835 BIU72_09520 BIZ41_16885 BJJ90_05265 BK248_12970 BK292_23205 BK334_11935 BK373_15870 BK375_10085 BK383_11680 BK400_05820 BMT49_17330 BMT53_21250 BMT91_11105 BN17_26661 BTQ04_11510 BTQ06_23845 BUE81_06975 BVL39_12970 BW690_04975 BWP17_05185 BXT93_24405 BZL31_00820 BZL69_02125 C1I57_04860 C2M16_17770 C2U48_20025 C3449_06035 C4J69_11655 C4K41_05275 C4M78_00835 C5715_23540 C5N07_06155 C5P01_05005 C5P43_15935 C5P44_09340 C6669_14670 C6986_17750 C6B13_03370 C7235_05745 C7B02_19400 C7B06_11630 C7B07_14530 C7B08_01430 C9E25_03325 CA593_12975 CCZ14_04445 CCZ17_10850 CDL37_13440 CG691_07365 CG692_07005 CG705_05530 CG706_07860 CIJ94_12220 COD30_01795 COD46_07095 CQP61_06810 CR538_05495 CR539_18815 CRE06_03485 CRM83_26360 CRT43_16405 CRT46_16440 CSB64_15850 CT143_09630 CT146_00680 CV83915_03339 CVH05_06295 CWM24_00790 CWS33_03125 CY655_17835 D0X26_06660 D1900_12730 D2183_19100 D2184_01135 D2185_02785 D2F89_14380 D3821_11140 D3O91_13425 D3Y67_06430 D4M06_10805 D6X47_20010 D7K63_03745 D7K66_09735 D7Y10_03025 D8Y29_15815 D9D20_04450 D9D33_19300 D9D43_17525 D9E22_07155 D9E35_20180 D9F17_11720 D9F57_14060 D9G11_10545 D9G42_05640 D9G48_11875 D9H53_12755 D9H68_17340 D9H70_12195 D9H94_16855 D9I18_10690 D9I20_00375 D9I47_00795 D9I87_07250 D9I88_14405 D9I97_09750 D9J03_22055 D9J11_17735 D9J44_16360 D9J46_14445 D9J60_10045 D9L89_10810 D9L99_02095 D9N32_10755 D9X97_06540 DD762_13665 DIV22_29760 DL455_11645 DL545_05995 DL800_20505 DM129_10705 DMI04_14240 DMZ31_10015 DNB37_12630 DNQ41_18960 DNR41_08670 DNX30_08935 DOY56_02000 DP258_16075 DP277_11440 DQE83_04685 DQO13_13250 DS732_20695 DS966_06010 DTL43_09355 DTL90_02675 DTM10_03745 DTM25_22630 DTM45_13530 DU310_11875 DU321_06150 DU333_12515 DW236_13020 DWB25_05920 E2855_03617 E2863_03463 EAI42_07155 EAI44_18400 EAI46_14335 EAI52_12500 EB509_19080 EB510_16355 EB515_03490 EC1094V2_904 EC1639_03756 EC3234A_48c00890 EC3426_03921 EC382_15705 EC95NR1_02021 Eco118UI_16400 ECONIH1_15890 ECs3640 ECTO124_01152 ECTO6_01068 ED225_00710 ED287_02625 ED600_14885 ED607_09825 ED611_00710 ED648_01520 ED903_09700 ED944_03505 EEA45_12675 EEP23_14050 EF173_03685 EFV01_14240 EFV02_06000 EFV04_18080 EFV06_07140 EFV08_05820 EFV11_00435 EFV12_15800 EFV14_04015 EFV15_05815 EFV16_07830 EFV17_00480 EGT48_09620 EGY17_03100 EIA08_07275 EIA13_21160 EIA21_04795 EJH97_05405 EL75_0914 EL79_0915 EL80_0918 EOL36_05365 ERS085365_02427 ERS085366_03042 ERS085374_03279 ERS085386_03410 ERS085416_02898 ERS139211_02072 ERS150873_02003 ERS150876_01467 FORC28_1110 GJ11_18025 HMPREF3040_01161 HW43_18180 JD73_16335 MJ49_17095 MS6198_30910 MS8345_02965 NCTC10082_03473 NCTC10090_04050 NCTC10418_01701 NCTC10444_01093 NCTC10764_00296 NCTC10766_00690 NCTC10767_02309 NCTC11022_02860 NCTC11112_00121 NCTC11181_03277 NCTC12950_01251 NCTC13125_04353 NCTC13127_01436 NCTC13462_04807 NCTC13846_01212 NCTC7927_01209 NCTC8500_01090 NCTC8960_03783 NCTC9007_03892 NCTC9036_01135 NCTC9037_01243 NCTC9044_00576 NCTC9045_01221 NCTC9050_04166 NCTC9058_00847 NCTC9062_02131 NCTC9075_01630 NCTC9077_01409 NCTC9081_05851 NCTC9112_01131 NCTC9117_01609 NCTC9119_01271 NCTC9434_01004 NCTC9702_01298 NCTC9706_03296 NCTC9775_04845 NCTC9777_02704 NCTC9969_01292 PU06_02080 RG28_07675 RK56_023165 SAMEA3472033_01264 SAMEA3472043_01265 SAMEA3472044_02272 SAMEA3472047_00339 SAMEA3472056_05455 SAMEA3472070_01673 SAMEA3472080_03155 SAMEA3472090_00131 SAMEA3472108_00527 SAMEA3472110_03462 SAMEA3472112_03722 SAMEA3472114_02432 SAMEA3472147_03296 SAMEA3484427_03298 SAMEA3484429_03415 SAMEA3484434_01581 SAMEA3485101_02257 SAMEA3485113_02257 SAMEA3752372_03639 SAMEA3752553_01510 SAMEA3752557_03040 SAMEA3752559_02995 SAMEA3752620_01282 SAMEA3753064_02287 SAMEA3753097_02219 SAMEA3753164_01192 SAMEA3753290_02847 SAMEA3753300_01107 SK85_03024 SY51_15605 UC41_20365 UN91_03645 WQ89_10170 WR15_06090 YDC107_1339] CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)
[aro-1 aro-2 aro-4 aro-5 aro-9 B14H13.20 NCU016321] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[lon lon_1 lon_2 lon_3 A6581_06540 A8C65_09155 A8G17_09470 A8M42_12205 A9819_02150 A9R57_08730 AC067_13940 AC789_1c04390 ACN77_08400 ACN81_24745 ACU57_11790 ACU90_20700 AJ318_07395 AM270_02090 AM446_21265 AM464_19190 AM465_24425 AMK83_09080 AML07_05605 AML35_17195 APT94_11405 APU18_24755 APZ14_19130 AUQ13_18305 AUS26_08525 AW059_13755 AW106_10030 AWE53_023455 AWF23_009230 AWF59_002015 AWF80_027560 AWG78_005680 AWP75_24635 AZZ83_000203 B1K96_09680 B7C53_07945 B9M99_03985 B9N33_08900 B9T59_05700 BANRA_00867 BANRA_00977 BANRA_01969 BANRA_02043 BANRA_03641 BANRA_04310 BB545_15795 BE963_16350 BER14_14325 BET08_18215 BFD68_17910 BHF46_21220 BHS81_02650 BIQ87_02425 BIU72_03070 BIZ41_19875 BJJ90_20055 BK248_01840 BK292_14395 BK334_05695 BK373_01080 BK375_01675 BK383_14710 BK400_22925 BMT49_03495 BMT53_08160 BMT91_05050 BN17_02431 BTQ06_01040 BUE81_06550 BVL39_00620 BW690_06825 BXT93_14065 BZL31_10455 BZL69_16545 C1I57_02830 C2M16_02950 C3449_08060 C4J69_09250 C4M78_17970 C5715_07650 C5N07_12995 C5P01_16055 C5P43_02540 C6669_02490 C6986_02640 C6B13_10210 C7235_18620 C7B06_13115 C7B07_14925 C7B08_06455 C9E25_04330 CA593_00935 CCZ14_02195 CCZ17_03875 CDL37_08925 CG692_04795 CG705_03025 CG706_02860 CIJ94_10835 COD30_15795 COD46_04600 CQP61_20635 CR538_19245 CR539_06435 CRD98_01930 CRT43_02425 CRT46_02355 CSB64_03555 CT143_00390 CT146_15985 CWM24_20160 CWS33_13550 CY655_02360 D0X26_07675 D1900_17610 D2183_00880 D2184_11270 D2185_12310 D2F89_19370 D3821_12655 D3O91_18250 D3Y67_14595 D5618_15420 D6X47_16730 D7Y10_06170 D8K42_15275 D8Y29_02110 D9D20_11240 D9D31_04875 D9D33_05815 D9D43_21565 D9E22_05125 D9E34_09980 D9E35_07020 D9E49_06700 D9F17_03270 D9F57_07485 D9G11_06315 D9H53_20830 D9H94_07265 D9I18_05150 D9I20_07000 D9I47_07695 D9I87_03565 D9I88_11055 D9J03_07390 D9J11_02395 D9J44_06085 D9J46_04320 D9J60_08825 D9L99_04615 D9N32_22800 DD762_17560 DIV22_26545 DL545_18880 DL800_04145 DM129_08665 DMZ31_12720 DNQ41_06120 DNQ45_04780 DNX30_05000 DP258_04840 DP277_07795 DQE83_14690 DQF57_07925 DQO13_05765 DS732_07170 DS966_18225 DTL43_07145 DTM10_06325 DTM25_22445 DTM45_11225 DU310_22610 DU321_07375 DU333_14745 DWB25_18925 E2855_00491 E2863_00475 EAI42_06530 EAI44_11230 EAI46_00915 EAI52_03190 EC1094V2_3409 EC1639_01225 EC3234A_4c01080 EC3426_01277 EC382_09250 EC95NR1_04662 Eco118UI_02490 ECONIH1_02385 ECTO124_03769 ECTO6_03661 ED287_10370 ED600_06055 ED648_01980 EEP23_01295 EFV01_15865 EFV02_00950 EFV04_09045 EFV06_11505 EFV11_06915 EFV12_04345 EFV14_05420 EFV16_10770 EFV17_08075 EGT48_21635 EGY17_15430 EIA08_09740 EIA13_09900 EJH97_18300 EOL36_01200 EPS76_04560 ERS085365_02395 ERS085374_02327 ERS085379_01165 ERS085383_00971 ERS085406_02176 ERS085416_01921 ERS139211_01924 ERS150876_00617 FORC28_4645 GJ11_02625 HMPREF3040_03444 HW43_05825 MJ49_04235 MS6198_04430 MS8345_00443 NCTC10082_01029 NCTC10090_01830 NCTC10418_05598 NCTC10764_05303 NCTC10766_05771 NCTC11022_05186 NCTC11181_01095 NCTC13462_01885 NCTC13846_03631 NCTC7922_06176 NCTC7927_04214 NCTC7928_04997 NCTC8179_01705 NCTC8196_01204 NCTC8959_05066 NCTC8960_01264 NCTC9007_00214 NCTC9036_03791 NCTC9037_03909 NCTC9050_01704 NCTC9055_00655 NCTC9058_03169 NCTC9062_04515 NCTC9111_03927 NCTC9117_04741 NCTC9434_02860 NCTC9703_03170 NCTC9706_01065 NCTC9777_00122 NCTC9969_03979 PU06_02695 RG28_02630 RK56_026450 RX35_02110 SAMEA3472033_03457 SAMEA3472043_02729 SAMEA3472044_00416 SAMEA3472047_02150 SAMEA3472055_02113 SAMEA3472070_02234 SAMEA3472080_01763 SAMEA3472090_01765 SAMEA3472108_01909 SAMEA3472110_00680 SAMEA3472112_02916 SAMEA3484427_03496 SAMEA3484429_01936 SAMEA3485113_01252 SAMEA3752372_02700 SAMEA3752553_00236 SAMEA3752557_00263 SAMEA3752559_02850 SAMEA3752620_00833 SAMEA3753097_00463 SAMEA3753164_00266 SAMEA3753300_00505 SK85_00464 SY51_02300 UC41_11885 UN86_09160 UN91_18465 WR15_04115 YDC107_3709] Lon protease (EC 3.4.21.53) (ATP-dependent protease La)
[hchA A8M42_01610 AM465_15370 AWF23_018680 AWF59_019055 AZZ83_004235 B9N33_26475 BFD68_20845 C1I57_21890 C7B02_06890 CCZ14_26645 CCZ17_22700 CRT43_11430 CT143_08220 D3C88_02905 D6X47_12880 D9D33_15385 D9E49_19020 D9I20_10460 D9J46_03345 DNR41_00375 DS966_16070 DU333_03260 DW236_02290 ECTO124_02024 EGT48_04930 EPS76_06485 ERS085406_02591 NCTC10766_03778 NCTC7928_05955 NCTC8450_02317 NCTC9007_02951 NCTC9075_02834 NCTC9775_01269 SY51_11150] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[] Genome polyprotein [Cleaved into: Core protein p21 (Capsid protein C) (p21); Core protein p19; Envelope glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2 (NS1) (gp68) (gp70); p7; Protease NS2-3 (p23) (EC 3.4.22.-); Serine protease NS3 (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Hepacivirin) (NS3P) (p70); Non-structural protein 4A (NS4A) (p8); Non-structural protein 4B (NS4B) (p27); Non-structural protein 5A (NS5A) (p56); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5B) (p68)]
[yjbN dus_1 dusA A6581_03815 A9819_23140 AC789_1c44580 ACN77_13265 ACN81_05795 AW059_18320 AWF80_023240 B1K96_03640 B7C53_20030 B9M99_07285 B9T59_11200 BANRA_00006 BANRA_02728 BANRA_02889 BANRA_03307 BANRA_05130 BB545_04715 BE963_11655 BHS81_24320 BIU72_20630 BN17_40231 BTQ06_28285 BUE81_22495 BVL39_04970 BWP17_09085 BXT93_20165 BZL69_05000 C2U48_12360 C4J69_17345 C4M78_06330 C5N07_20225 C5P01_10975 C5P43_26750 C6669_07250 C7235_23350 C7B02_13830 CA593_05650 CG691_24515 CG705_24980 CG706_06955 CIJ94_13445 COD46_18670 CQP61_25690 CR538_23810 CRD98_24950 CRM83_18265 CVH05_02240 CWS33_16005 CY655_25665 D0X26_12230 D3821_04670 D3822_08770 D5618_12235 D6X47_24985 D7K63_02810 D8K42_02240 D8Y29_22820 D9D31_22380 D9E34_02100 D9G11_16395 D9I88_03920 D9I97_23040 D9J03_04435 D9J44_17705 DD762_09595 DL545_23295 DMZ31_05365 DNQ41_01750 DP277_17700 DQE83_12890 DQF57_12565 DQO13_07475 DS732_01940 DU310_10975 DU321_20725 EAI42_11800 EAI46_13935 EB510_19460 EC1639_00374 EC3234A_77c00420 EC3426_00373 Eco118UI_23990 ED287_08370 EEP23_23845 EF173_02750 EFV02_20690 EFV04_19480 EFV06_17385 EFV11_14225 EFV12_14460 EFV14_16985 EFV16_16620 EFV17_15560 EJH97_22895 EL75_4140 EL79_4345 EL80_4252 EOL36_08950 ERS085374_01630 ERS085383_01453 ERS085404_01248 HMPREF3040_01367 NCTC10090_02700 NCTC10418_07037 NCTC10764_02883 NCTC10865_05778 NCTC11112_02403 NCTC11181_01881 NCTC11341_02874 NCTC12950_05132 NCTC7927_05171 NCTC8450_00470 NCTC8985_03929 NCTC9037_04708 NCTC9044_02384 NCTC9045_05465 NCTC9050_02741 NCTC9062_03523 NCTC9077_05824 NCTC9701_04921 NCTC9702_05560 NCTC9775_03044 NCTC9777_01046 RK56_017030 RX35_03830 SAMEA3446340_04610 SAMEA3472055_01598 SAMEA3472108_01690 SAMEA3472114_02034 SAMEA3472147_04808 SAMEA3484427_03836 SAMEA3484429_02481 SAMEA3752553_02493 SAMEA3752559_00279 SAMEA3753064_01454 SAMEA3753290_01943 SAMEA3753300_00780] tRNA-dihydrouridine(20/20a) synthase (EC 1.3.1.-) (EC 1.3.1.91) (U20-specific dihydrouridine synthase) (U20-specific Dus) (tRNA-dihydrouridine synthase A)
[deoB ECH7EC869_5382] Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)
[iscS iscS_1 A6581_02145 A6592_14885 A8C65_03965 A8G17_10685 A8M42_18685 A9819_14635 A9R57_16930 AC067_03015 AC789_1c28660 ACN77_09430 ACN81_26435 ACU57_06285 ACU90_01375 AJ318_26005 AKG99_22280 AM270_07100 AM446_08145 AM464_04450 AM465_11700 AMK83_11225 AML07_10540 AML35_21525 APT94_12335 APU18_00295 APZ14_05615 ARC77_08945 AU473_09315 AUQ13_13105 AUS26_21555 AW059_05940 AW106_10960 AWE53_011210 AWF23_021680 AWF59_015590 AWF80_014980 AWG78_019485 AWP75_00135 AZZ83_002723 B1K96_17760 B7C53_13290 B9M99_15840 B9N33_21250 B9T59_21105 BANRA_01075 BANRA_01564 BANRA_03228 BANRA_03396 BANRA_04417 BANRA_04547 BE963_28425 BEN53_15845 BER14_02655 BET08_22520 BFD68_15155 BHF46_00575 BHS81_15460 BHS87_14335 BIQ87_14690 BIU72_16435 BIZ41_13705 BJJ90_06620 BK248_16700 BK292_20650 BK334_04895 BK373_05915 BK375_00880 BK383_22845 BK400_09035 BMT49_16180 BMT53_23050 BMT91_09840 BTQ04_10030 BTQ06_16545 BUE81_08125 BVL39_14165 BW690_04500 BWP17_17035 BZL31_13665 BZL69_10285 C1I57_24205 C2M16_05920 C2U48_21435 C3449_00330 C4J69_10615 C4K41_12560 C4M78_10890 C5N07_10225 C5P01_05670 C5P43_04165 C5P44_15165 C6669_16070 C6986_16375 C6B13_21190 C7235_06915 C7B02_18515 C7B06_11270 C7B07_12285 C7B08_05430 CA593_14170 CCZ14_18705 CCZ17_22060 CDL37_24785 CG691_06060 CG692_02695 CG705_05185 CG706_03765 CIJ94_05825 COD30_00935 COD46_11390 CQP61_07985 CR539_17655 CRD98_15000 CRE06_08785 CRM83_27605 CRT43_15115 CRT46_15245 CSB64_12500 CT143_05820 CT146_18385 CV83915_03587 CVH05_18115 CWM24_13125 CWS33_10120 CY655_16470 D0X26_11620 D1900_21335 D2183_14465 D2184_18615 D2185_06580 D2F89_15600 D3821_11555 D3822_04800 D3O91_03680 D3Y67_12505 D4M06_06155 D5618_17320 D6X47_12765 D7K63_08185 D7K66_06980 D7Y10_10280 D8K42_11260 D8Y29_14705 D9D20_07450 D9D31_00305 D9D43_10015 D9E22_02900 D9E34_00305 D9E35_16470 D9E49_14255 D9F17_05510 D9F57_11940 D9G11_04535 D9G42_20475 D9G48_08355 D9H53_16005 D9H68_00875 D9H70_10250 D9I18_09755 D9I20_05605 D9I47_13045 D9I87_02710 D9I88_00300 D9I97_08015 D9J03_03570 D9J11_04400 D9J44_00170 D9J46_20935 D9J60_17685 D9L89_07985 D9L99_09605 D9N32_09595 D9X97_18160 DD762_08545 DIV22_32035 DL545_07355 DL800_19085 DM129_09135 DMI04_05945 DMZ31_01825 DNB37_08745 DNQ41_17815 DNR41_15780 DNX30_07365 DOY56_06530 DP258_15600 DP277_03730 DQE83_18635 DQF57_10730 DQO13_10660 DS732_18775 DS966_02860 DTL43_01800 DTL90_08325 DTM10_01260 DTM25_14855 DTM45_09080 DU310_00575 DU321_15890 DU333_02600 DW236_17345 DWB25_07065 E2855_03279 E2863_03186 EAI42_06440 EAI44_09300 EAI46_19320 EAI52_02850 EB509_00845 EB510_14520 EB515_08445 EC1094V2_1138 EC1639_03484 EC3234A_44c01370 EC3426_03682 EC382_15780 EC95NR1_01752 Eco118UI_15095 ECONIH1_14765 ECTO124_01368 ECTO6_01302 ED225_05585 ED287_00180 ED600_07660 ED607_17205 ED611_05750 ED648_04515 ED903_11540 ED944_08680 EEA45_00840 EEP23_02460 EF173_08030 EFV01_13825 EFV02_11980 EFV04_05925 EFV06_05255 EFV08_03330 EFV11_08830 EFV12_11910 EFV14_12485 EFV15_03245 EFV16_03880 EFV17_11965 EGT48_08260 EGY17_01970 EIA08_10505 EIA13_01725 EIA21_07385 EJH97_06540 EL75_1117 EL79_1128 EL80_1131 EOL36_06090 EPS76_15875 ERS085365_01538 ERS085366_02045 ERS085374_00061 ERS085379_00921 ERS085383_02049 ERS085386_03188 ERS085404_01057 ERS085406_03472 ERS085411_02202 ERS085416_01266 ERS139211_00888 ERS150873_01415 ERS150876_00833 FORC28_1424 HW43_17050 JD73_17725 MJ49_18275 MS6198_28580 MS8345_02723 NCTC10090_04376 NCTC10444_01323 NCTC10766_01180 NCTC10767_02594 NCTC11181_03575 NCTC11341_00889 NCTC12950_01537 NCTC13125_04632 NCTC13462_05052 NCTC13846_01437 NCTC7922_00893 NCTC7927_01500 NCTC7928_01371 NCTC8009_03115 NCTC8179_04409 NCTC8196_03366 NCTC8450_04290 NCTC8500_01442 NCTC8621_01401 NCTC8959_02462 NCTC8960_04060 NCTC8985_06161 NCTC9007_03642 NCTC9036_01412 NCTC9037_01482 NCTC9044_00276 NCTC9045_01545 NCTC9050_04644 NCTC9055_03293 NCTC9058_00608 NCTC9062_01792 NCTC9073_04547 NCTC9075_01973 NCTC9111_01941 NCTC9112_01437 NCTC9119_01524 NCTC9434_01284 NCTC9701_01429 NCTC9703_01091 NCTC9706_04616 NCTC9775_05141 NCTC9777_02572 NCTC9962_00698 NCTC9969_01533 PU06_05300 RG28_09220 RK56_021935 RX35_01423 SAMEA3446340_03850 SAMEA3472033_00658 SAMEA3472043_01035 SAMEA3472044_02985 SAMEA3472047_01032 SAMEA3472055_00937 SAMEA3472056_00874 SAMEA3472070_00065 SAMEA3472080_01607 SAMEA3472090_01244 SAMEA3472108_03497 SAMEA3472110_00486 SAMEA3472112_00780 SAMEA3472114_03249 SAMEA3472147_00165 SAMEA3484427_00440 SAMEA3484429_00549 SAMEA3484434_00296 SAMEA3485101_04492 SAMEA3485113_03372 SAMEA3752372_01122 SAMEA3752553_02304 SAMEA3752557_00969 SAMEA3752559_00692 SAMEA3752620_00062 SAMEA3753064_03100 SAMEA3753097_02751 SAMEA3753164_00628 SAMEA3753290_03552 SAMEA3753300_01026 SK85_02782 SY51_14535 UC41_13245 UN91_26515 WQ89_05730 WR15_01190 YDC107_1108] Cysteine desulfurase IscS (EC 2.8.1.7)
[deoB deoB_2 AM465_00215 AWF23_006585 AWG78_008375 AZZ83_003142 B9N33_07855 BFD68_03190 BIQ87_25045 BK373_08645 BMT49_01195 C1I57_14295 C3449_18360 C4K41_14930 CCZ14_20825 CCZ17_11270 CRT43_26650 CT146_13160 D1900_16515 D9D33_04390 D9F17_01095 D9I47_05025 D9J46_22240 DTM10_01805 ECTO124_04248 EGT48_19225 ERS085406_00372 MJ49_07145 MS8345_05097 NCTC9075_05740 NCTC9434_02414 SAMEA3472090_00804 SAMEA3752620_01903 SAMEA3753164_02620 SY51_25230] Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)

Bibliography :
[28347766] Biosynthesis of an antiviral compound using a stabilized phosphopentomutase by multipoint covalent immobilization.
[26924489] A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritima.
[22329805] Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase.
[21193409] Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle.
[19818317] Screening and characterization of a phosphopentomutase useful for enzymatic production of 2'-deoxyribonucleoside.
[18776493] Coupled biocatalysts applied to the synthesis of nucleosides.
[17804405] Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family.
[16893570] Methods for the determination of intracellular levels of ribose phosphates.
[16786272] One-pot microbial synthesis of 2'-deoxyribonucleoside from glucose, acetaldehyde, and a nucleobase.
[15205420] Presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism in the hyperthermophilic archaeon Thermococcus kodakaraensis.