GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Protein phosphatase 1 regulatory subunit 12A (130 kDa myosin-binding subunit of smooth muscle myosin phosphatase) (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (PP1M subunit M110) (Protein phosphatase myosin-binding subunit)

 MYPT1_CHICK             Reviewed;        1004 AA.
Q90623; Q10727; Q90624;
16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
01-NOV-1996, sequence version 1.
02-JUN-2021, entry version 133.
RecName: Full=Protein phosphatase 1 regulatory subunit 12A;
AltName: Full=130 kDa myosin-binding subunit of smooth muscle myosin phosphatase;
AltName: Full=Myosin phosphatase-targeting subunit 1;
Short=Myosin phosphatase target subunit 1;
AltName: Full=PP1M subunit M110;
AltName: Full=Protein phosphatase myosin-binding subunit;
Name=PPP1R12A; Synonyms=MBS, MYPT1;
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
Phasianinae; Gallus.
NCBI_TaxID=9031;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), PARTIAL PROTEIN SEQUENCE,
FUNCTION, SUBUNIT, INTERACTION WITH MYOSIN, AND TISSUE SPECIFICITY.
TISSUE=Gizzard;
PubMed=7982954;
Shimizu H., Ito M., Miyahara M., Ichikawa K., Okubo S., Konishi T.,
Naka M., Tanaka T., Hirano K., Hartshorne D.J., Nakano T.;
"Characterization of the myosin-binding subunit of smooth muscle myosin
phosphatase.";
J. Biol. Chem. 269:30407-30411(1994).
[2]
NUCLEOTIDE SEQUENCE [MRNA] OF 681-1004, AND PARTIAL PROTEIN SEQUENCE.
TISSUE=Gizzard;
PubMed=7988720; DOI=10.1016/0014-5793(94)01231-8;
Chen Y.H., Chen M.X., Alessi D.R., Campbell D.G., Shanahan C., Cohen P.,
Cohen P.T.W.;
"Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory
subunits of smooth muscle protein phosphatase 1M.";
FEBS Lett. 356:51-55(1994).
[3]
PARTIAL PROTEIN SEQUENCE, IDENTIFICATION BY MASS SPECTROMETRY, AND
PHOSPHORYLATION AT THR-695 AND THR-850.
PubMed=12220642; DOI=10.1016/s0014-5793(02)03175-7;
Velasco G., Armstrong C., Morrice N., Frame S., Cohen P.;
"Phosphorylation of the regulatory subunit of smooth muscle protein
phosphatase 1M at Thr850 induces its dissociation from myosin.";
FEBS Lett. 527:101-104(2002).
[4]
PHOSPHORYLATION AT THR-695 AND THR-850, AND MUTAGENESIS OF THR-695 AND
THR-850.
PubMed=10601309; DOI=10.1074/jbc.274.52.37385;
Feng J., Ito M., Ichikawa K., Isaka N., Nishikawa M., Hartshorne D.J.,
Nakano T.;
"Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle
myosin phosphatase.";
J. Biol. Chem. 274:37385-37390(1999).
[5]
PHOSPHORYLATION BY DMPK.
PubMed=11287000; DOI=10.1016/s0014-5793(01)02283-9;
Muranyi A., Zhang R., Liu F., Hirano K., Ito M., Epstein H.F.,
Hartshorne D.J.;
"Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase
targeting subunit and inhibits myosin phosphatase activity.";
FEBS Lett. 493:80-84(2001).
[6]
X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 1-299 IN COMPLEX WITH PPP1CB.
PubMed=15164081; DOI=10.1038/nature02582;
Terrak M., Kerff F., Langsetmo K., Tao T., Dominguez R.;
"Structural basis of protein phosphatase 1 regulation.";
Nature 429:780-784(2004).
-!- FUNCTION: Regulates myosin phosphatase activity.
{ECO:0000269|PubMed:7982954}.
-!- SUBUNIT: PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC,
and one or several targeting or regulatory subunits (By similarity).
PPP1R12A mediates binding to myosin. {ECO:0000250,
ECO:0000269|PubMed:15164081, ECO:0000269|PubMed:7982954}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O14974}.
Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:O14974}.
Note=Also along actomyosin filaments. {ECO:0000250|UniProtKB:O14974}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1; Synonyms=M133;
IsoId=Q90623-1; Sequence=Displayed;
Name=2; Synonyms=M130;
IsoId=Q90623-2; Sequence=VSP_035912;
-!- TISSUE SPECIFICITY: Detected in brain, lung, aorta, heart, gizzard,
stomach, oviduct, spleen, kidney and small intestine.
{ECO:0000269|PubMed:7982954}.
-!- PTM: Phosphorylated by CIT (Rho-associated kinase) and by ROCK2 on
serine and threonine residues. Phosphorylation at Thr-695 leads to
inhibition of myosin phosphatase activity. Phosphorylation at Thr-850
abolishes myosin binding. May be phosphorylated at Thr-695 by DMPK; may
inhibit the myosin phosphatase activity. {ECO:0000269|PubMed:10601309,
ECO:0000269|PubMed:11287000, ECO:0000269|PubMed:12220642}.
---------------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
---------------------------------------------------------------------------
EMBL; D37985; BAA07201.1; -; mRNA.
EMBL; D37986; BAA07202.1; -; mRNA.
EMBL; S74623; AAB32730.1; -; mRNA.
PIR; A55142; A55142.
RefSeq; NP_990454.1; NM_205123.1. [Q90623-1]
RefSeq; XP_015133641.1; XM_015278155.1.
RefSeq; XP_015133841.1; XM_015278355.1. [Q90623-2]
PDB; 1S70; X-ray; 2.70 A; B=1-299.
PDBsum; 1S70; -.
BMRB; Q90623; -.
SMR; Q90623; -.
BioGRID; 676290; 1.
ELM; Q90623; -.
IntAct; Q90623; 1.
STRING; 9031.ENSGALP00000016789; -.
iPTMnet; Q90623; -.
PaxDb; Q90623; -.
PRIDE; Q90623; -.
Ensembl; ENSGALT00000065339; ENSGALP00000055263; ENSGALG00000010325. [Q90623-1]
Ensembl; ENSGALT00000090229; ENSGALP00000062528; ENSGALG00000010325. [Q90623-2]
GeneID; 396020; -.
KEGG; gga:396020; -.
CTD; 4659; -.
eggNOG; KOG0505; Eukaryota.
GeneTree; ENSGT00940000156120; -.
InParanoid; Q90623; -.
OMA; ETQVNNI; -.
OrthoDB; 477969at2759; -.
PhylomeDB; Q90623; -.
BRENDA; 3.1.3.53; 1306.
EvolutionaryTrace; Q90623; -.
PRO; PR:Q90623; -.
Proteomes; UP000000539; Chromosome 1.
ExpressionAtlas; Q90623; baseline and differential.
GO; GO:0031672; C:A band; ISS:UniProtKB.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO; GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO; GO:0030018; C:Z disc; ISS:UniProtKB.
GO; GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.
GO; GO:0004857; F:enzyme inhibitor activity; IBA:GO_Central.
GO; GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB.
GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
GO; GO:0035508; P:positive regulation of myosin-light-chain-phosphatase activity; IBA:GO_Central.
GO; GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.
GO; GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.
GO; GO:0007165; P:signal transduction; IEA:InterPro.
DisProt; DP00218; -.
Gene3D; 1.25.40.20; -; 2.
InterPro; IPR002110; Ankyrin_rpt.
InterPro; IPR020683; Ankyrin_rpt-contain_dom.
InterPro; IPR036770; Ankyrin_rpt-contain_sf.
InterPro; IPR017401; MYPT1/MYPT2/Mbs85.
InterPro; IPR031775; PRKG1_interact.
Pfam; PF12796; Ank_2; 2.
Pfam; PF15898; PRKG1_interact; 1.
PIRSF; PIRSF038141; PP1_12ABC_vert; 1.
SMART; SM00248; ANK; 6.
SUPFAM; SSF48403; SSF48403; 1.
PROSITE; PS50297; ANK_REP_REGION; 1.
PROSITE; PS50088; ANK_REPEAT; 4.
1: Evidence at protein level;
3D-structure; Alternative splicing; ANK repeat; Cytoplasm; Cytoskeleton;
Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat.
CHAIN 1..1004
/note="Protein phosphatase 1 regulatory subunit 12A"
/id="PRO_0000355556"
REPEAT 39..68
/note="ANK 1"
REPEAT 72..101
/note="ANK 2"
REPEAT 105..134
/note="ANK 3"
REPEAT 138..164
/note="ANK 4"
REPEAT 198..227
/note="ANK 5"
REPEAT 231..260
/note="ANK 6"
REGION 35..38
/note="Important for interaction with PPP1CB"
REGION 291..920
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 303..331
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 332..355
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 374..413
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 414..431
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 539..613
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 637..658
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 659..685
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 707..765
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 766..811
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 812..839
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 859..883
/note="Basic and acidic residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 884..911
/note="Polar residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
MOD_RES 695
/note="Phosphothreonine; by ROCK2"
/evidence="ECO:0000269|PubMed:10601309,
ECO:0000269|PubMed:12220642"
MOD_RES 850
/note="Phosphothreonine; by ROCK2"
/evidence="ECO:0000269|PubMed:10601309,
ECO:0000269|PubMed:12220642"
VAR_SEQ 512..552
/note="Missing (in isoform 2)"
/evidence="ECO:0000303|PubMed:7982954"
/id="VSP_035912"
MUTAGEN 695
/note="T->A: Reduces phosphorylation. Reduces
phosphorylation on serine and threonine residues by 80%;
when associated with A-850."
/evidence="ECO:0000269|PubMed:10601309"
MUTAGEN 850
/note="T->A: Reduces phosphorylation. Reduces
phosphorylation on serine and threonine residues by 80%;
when associated with A-695."
/evidence="ECO:0000269|PubMed:10601309"
HELIX 4..19
/evidence="ECO:0007829|PDB:1S70"
TURN 20..22
/evidence="ECO:0007829|PDB:1S70"
HELIX 40..50
/evidence="ECO:0007829|PDB:1S70"
HELIX 53..62
/evidence="ECO:0007829|PDB:1S70"
HELIX 76..82
/evidence="ECO:0007829|PDB:1S70"
HELIX 86..94
/evidence="ECO:0007829|PDB:1S70"
HELIX 109..116
/evidence="ECO:0007829|PDB:1S70"
HELIX 119..127
/evidence="ECO:0007829|PDB:1S70"
HELIX 142..145
/evidence="ECO:0007829|PDB:1S70"
HELIX 149..162
/evidence="ECO:0007829|PDB:1S70"
HELIX 166..187
/evidence="ECO:0007829|PDB:1S70"
TURN 196..198
/evidence="ECO:0007829|PDB:1S70"
HELIX 202..209
/evidence="ECO:0007829|PDB:1S70"
HELIX 212..219
/evidence="ECO:0007829|PDB:1S70"
TURN 220..222
/evidence="ECO:0007829|PDB:1S70"
HELIX 235..241
/evidence="ECO:0007829|PDB:1S70"
HELIX 245..253
/evidence="ECO:0007829|PDB:1S70"
TURN 268..270
/evidence="ECO:0007829|PDB:1S70"
HELIX 275..277
/evidence="ECO:0007829|PDB:1S70"
HELIX 278..286
/evidence="ECO:0007829|PDB:1S70"
SEQUENCE 1004 AA; 111606 MW; 7ED870DB87046929 CRC64;
MKMADAKQKR NEQLKRWIGS ETDLEPPVVK RKKTKVKFDD GAVFLAACSS GDTEEVLRLL
ERGADINYAN VDGLTALHQA CIDDNVDMVK FLVENGANIN QPDNEGWIPL HAAASCGYLD
IAEYLISQGA HVGAVNSEGD TPLDIAEEEA MEELLQNEVN RQGVDIEAAR KEEERIMLRD
ARQWLNSGHI NDVRHAKSGG TALHVAAAKG YTEVLKLLIQ ARYDVNIKDY DGWTPLHAAA
HWGKEEACRI LVENLCDMEA VNKVGQTAFD VADEDILGYL EELQKKQNLL HSEKREKKSP
LIESTANLDN NQTQKTFKNK ETLIMEQEKN ASSIESLEHE KADEEEEGKK DESSCSSEEE
EDDDSESEAE TDKAKTLANA NTTSTQSASM TAPSVAGGQG TPTSPLKKFP TSTTKVSPKE
EERKDESPAS WRLGLRKTGS YGALAEITAS KEAQKEKDSA GVIRSASSPR LSSSLDNKEK
EKDGKGTRLA YVAPTIPRRL ASTSDIDEKE NRDSSASSIR SGSSYARRKW EEDVKKNSLN
EGPTSLNTSY QRSGSFGRRQ DDLVSSNVPS TASTVTSSAG LQKTLPASAN TTTKSTTGST
SAGVQSSTSN RLWAEDSTEK EKDSVPTAVT VPVAPSVVNA AATTTAMTTA TSGTVSSTSE
VRERRRSYLT PVRDEESESQ RKARSRQARQ SRRSTQGVTL TDLQEAEKTI GRSRSTRTRE
QENEEKEKEE KEKQDKEKQE EKKESETKDD DYRQRYSRTV EEPYHRYRPT STSTSTSSTS
SLSTSTSSLS SSSQLNRPNS LIGITSAYSR SGTKESEREG GKKEEEKEED KSQPKSIRER
RRPREKRRST GVSFWTQDSD ENEQEHQSDS EEGTNKKETQ SDSLSRYDTG SLSVSSGDRY
DSAQGRSGSQ SYLEDRKPYC SRLEKEDSTD FKKLYEQILA ENEKLKAQLH DTNMELTDLK
LQLEKTTQRQ ERFADRSLLE MEKRVSGKSQ YLLGGKKSSR KKDI


Related products :

Catalog number Product name Quantity
EIAAB26153 130 kDa myosin-binding subunit of smooth muscle myosin phophatase,Chicken,Gallus gallus,MBS,Myosin phosphatase target subunit 1,Myosin phosphatase-targeting subunit 1,MYPT1,PP1M subunit M110,PPP1R12A,
EIAAB26151 Homo sapiens,Human,MBS,Myosin phosphatase target subunit 1,Myosin phosphatase-targeting subunit 1,MYPT1,PPP1R12A,Protein phosphatase 1 regulatory subunit 12A,Protein phosphatase myosin-binding subunit
EIAAB26152 Mbs,MBSP,Myosin phosphatase target subunit 1,Myosin phosphatase-targeting subunit 1,Mypt1,PP-1M,Ppp1r12a,Protein phosphatase 1 regulatory subunit 12A,Protein phosphatase myosin-binding subunit,Protein
EIAAB26156 Homo sapiens,Human,Myosin phosphatase target subunit 2,Myosin phosphatase-targeting subunit 2,MYPT2,PPP1R12B,Protein phosphatase 1 regulatory subunit 12B
EIAAB26155 Mouse,Mus musculus,Myosin phosphatase target subunit 2,Myosin phosphatase-targeting subunit 2,Mypt2,Ppp1r12b,Protein phosphatase 1 regulatory subunit 12B
EIAAB26154 Mouse,Mus musculus,Myosin phosphatase target subunit 1,Myosin phosphatase-targeting subunit 1,Mypt1,Ppp1r12a,Protein phosphatase 1 regulatory subunit 12A
EIAAB31850 Homo sapiens,Human,LENG3,MBS85,PPP1R12C,Protein phosphatase 1 myosin-binding subunit of 85 kDa,Protein phosphatase 1 myosin-binding subunit p85,Protein phosphatase 1 regulatory subunit 12C
EIAAB31851 Mbs85,Mouse,Mus musculus,Ppp1r12c,Protein phosphatase 1 myosin-binding subunit of 85 kDa,Protein phosphatase 1 myosin-binding subunit p85,Protein phosphatase 1 regulatory subunit 12C
EIAAB31868 Mouse,Mus musculus,Myosin phosphatase targeting subunit 3,Mypt3,Ppp1r16a,Protein phosphatase 1 regulatory subunit 16A
EIAAB31869 Homo sapiens,Human,Myosin phosphatase-targeting subunit 3,MYPT3,PPP1R16A,Protein phosphatase 1 regulatory subunit 16A
EIAAB32122 Homo sapiens,Human,PP1 subunit R6,PPP1R3D,PPP1R6,Protein phosphatase 1 regulatory subunit 3D,Protein phosphatase 1 regulatory subunit 6,Protein phosphatase 1-binding subunit R6
EIAAB32117 Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL,Homo sapiens,Human,PP1 subunit R4,PPP1R3B,PPP1R4,Protein phosphatase 1 regulatory subunit 3B,Protein phosphatase 1 regulatory sub
EIAAB32116 Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL,Mouse,Mus musculus,PP1 subunit R4,Ppp1r3b,Ppp1r4,Protein phosphatase 1 regulatory subunit 3B,Protein phosphatase 1 regulatory sub
EIAAB32114 33 kDa glycogen-binding protein,Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL,PP1 subunit R4,Ppp1r3b,Ppp1r4,Protein phosphatase 1 regulatory subunit 3B,Protein phosphatase 1 r
EIAAB32113 Homo sapiens,Human,PP1G,PPP1R3A,Protein phosphatase 1 glycogen-associated regulatory subunit,Protein phosphatase 1 regulatory subunit 3A,Protein phosphatase type-1 glycogen targeting subunit,RG1
EIAAB32112 Oryctolagus cuniculus,PP1G,PPP1R3A,Protein phosphatase 1 glycogen-associated regulatory subunit,Protein phosphatase 1 regulatory subunit 3A,Protein phosphatase type-1 glycogen targeting subunit,Rabbit
EIAAB32111 Mouse,Mus musculus,Pp1g,Ppp1r3a,Protein phosphatase 1 glycogen-associated regulatory subunit,Protein phosphatase 1 regulatory subunit 3A,Protein phosphatase type-1 glycogen targeting subunit,RG1
EIAAB29458 Homo sapiens,Human,PP2A subunit B isoform PR48,PPP2R3B,PPP2R3L,Protein phosphatase 2A 48 kDa regulatory subunit,Serine_threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
EIAAB32120 Homo sapiens,Human,PP1 subunit R5,PPP1R3C,PPP1R5,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,Protein targeting to glycogen,PTG
EIAAB32119 Bos taurus,Bovine,PP1 subunit R5,PPP1R3C,PPP1R5,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,Protein targeting to glycogen,PTG
EIAAB32121 Mouse,Mus musculus,PP1 subunit R5,Ppp1r3c,Ppp1r5,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,Protein targeting to glycogen,PTG
EIAAB32118 PP1 subunit R5,Ppp1r3c,Ppp1r5,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,Protein targeting to glycogen,PTG,Rat,Rattus norvegicus
E1323h ELISA kit Calcineurin subunit B type 1,CNA2,CNB,Homo sapiens,Human,PPP3R1,Protein phosphatase 2B regulatory subunit 1,Protein phosphatase 3 regulatory subunit B alpha isoform 1 96T
E1323h ELISA Calcineurin subunit B type 1,CNA2,CNB,Homo sapiens,Human,PPP3R1,Protein phosphatase 2B regulatory subunit 1,Protein phosphatase 3 regulatory subunit B alpha isoform 1 96T
U1323h CLIA Calcineurin subunit B type 1,CNA2,CNB,Homo sapiens,Human,PPP3R1,Protein phosphatase 2B regulatory subunit 1,Protein phosphatase 3 regulatory subunit B alpha isoform 1 96T
Pathways :
WP2292: Chemokine signaling pathway
WP1644: DNA replication
WP1694: Pyrimidine metabolism
WP1693: Purine metabolism
WP2272: Pathogenic Escherichia coli infection
WP1663: Homologous recombination
WP1566: Citrate cycle (TCA cycle)
WP1672: Mismatch repair
WP1654: gamma-Hexachlorocyclohexane degradation
WP1626: Benzoate degradation via CoA ligation
WP1655: Geraniol degradation
WP1614: 1- and 2-Methylnaphthalene degradation
WP1711: Trinitrotoluene degradation
WP1671: Methane metabolism
WP1718: Vitamin B6 metabolism
WP1680: Oxidative phosphorylation
WP1634: Butanoate metabolism
WP2349: vitamin B3 (niacin), NAD and NADP biosynthesis pathway
WP1696: Riboflavin metabolism
WP76: TCA Cycle
WP2341: vitamin B1 (thiamin) biosynthesis and salvage pathway
WP1709: Thiamine metabolism
WP2340: Thiamine (vitamin B1) biosynthesis and salvage
WP2353: vitamin B9 (folate) biosynthesis pathway
WP1652: Fructose and mannose metabolism

Related Genes :
[PPP1R12A MBS MYPT1] Protein phosphatase 1 regulatory subunit 12A (130 kDa myosin-binding subunit of smooth muscle myosin phosphatase) (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (PP1M subunit M110) (Protein phosphatase myosin-binding subunit)
[Ppp1r12a Mbs Mypt1] Protein phosphatase 1 regulatory subunit 12A (MBSP) (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) (Protein phosphatase subunit 1M) (PP-1M) (Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110)
[PPP1R12A MBS MYPT1] Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
[ppp1r12a mbs mypt1 si:dkey-28j4.1 zgc:110448] Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
[Ppp1r12a Mypt1] Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)
[PPP1R12B MYPT2] Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
[PPP1R12C LENG3 MBS85] Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)
[Ppp1cc] Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[MYLK MLCK MLCK1 MYLK1] Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]
[PPP1CC] Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
[PPP1R10 CAT53 FB19 PNUTS] Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99)
[Ppp1cc] Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
[Ppp1r12b Mypt2] Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
[PPP1CC] Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[Ppp1cb] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[Ppp1cb] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[Myl2 Mlc2] Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v)
[PPP2R3A PPP2R3] Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B)
[MYH11 KIAA0866] Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)
[PPP1CA PPP1A] Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
[PPP1CC] Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
[PPP1CA PPP1A] Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
[Ppp1ca Ppp1a] Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
[Ppp1ca Ppp1a] Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)

Bibliography :
No related Items