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Putative dna-binding bright/brcaa1/rbp1 (Fragment)

 A0A023F3J5_TRIIF        Unreviewed;      1930 AA.
A0A023F3J5;
11-JUN-2014, integrated into UniProtKB/TrEMBL.
11-JUN-2014, sequence version 1.
07-NOV-2018, entry version 20.
SubName: Full=Putative dna-binding bright/brcaa1/rbp1 {ECO:0000313|EMBL:JAC15906.1};
Flags: Fragment;
Triatoma infestans (Assassin bug).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Paraneoptera; Hemiptera; Heteroptera;
Panheteroptera; Cimicomorpha; Reduviidae; Triatominae; Triatoma.
NCBI_TaxID=30076 {ECO:0000313|EMBL:JAC15906.1};
[1] {ECO:0000313|EMBL:JAC15906.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Chile {ECO:0000313|EMBL:JAC15906.1};
TISSUE=Salivary glands {ECO:0000313|EMBL:JAC15906.1};
PubMed=25474469;
Schwarz A., Medrano-Mercado N., Schaub G.A., Struchiner C.J.,
Bargues M.D., Levy M.Z., Ribeiro J.M.;
"An updated insight into the Sialotranscriptome of Triatoma infestans:
developmental stage and geographic variations.";
PLoS Negl. Trop. Dis. 8:E3372-E3372(2014).
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00704572}.
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EMBL; GBBI01002806; JAC15906.1; -; mRNA.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
CDD; cd00024; CHROMO; 1.
Gene3D; 1.10.150.60; -; 1.
InterPro; IPR001606; ARID_dom.
InterPro; IPR036431; ARID_dom_sf.
InterPro; IPR016197; Chromo-like_dom_sf.
InterPro; IPR000953; Chromo/chromo_shadow_dom.
InterPro; IPR012603; RBB1NT.
InterPro; IPR002999; Tudor.
InterPro; IPR025995; Tudor-knot.
Pfam; PF01388; ARID; 1.
Pfam; PF08169; RBB1NT; 1.
Pfam; PF11717; Tudor-knot; 1.
SMART; SM00501; BRIGHT; 1.
SMART; SM00298; CHROMO; 1.
SMART; SM00333; TUDOR; 1.
SUPFAM; SSF46774; SSF46774; 1.
SUPFAM; SSF54160; SSF54160; 1.
PROSITE; PS51011; ARID; 1.
2: Evidence at transcript level;
Coiled coil {ECO:0000256|SAM:Coils};
DNA-binding {ECO:0000313|EMBL:JAC15906.1};
Nucleus {ECO:0000256|SAAS:SAAS00704574}.
DOMAIN 292 383 ARID. {ECO:0000259|PROSITE:PS51011}.
COILED 1897 1930 {ECO:0000256|SAM:Coils}.
NON_TER 1 1 {ECO:0000313|EMBL:JAC15906.1}.
SEQUENCE 1930 AA; 214908 MW; B0E6FB11B905A8D9 CRC64;
EEPPYLSVDT DVSAKYKGAF CEAKIRKVVR SVKCKVVFKQ GWGSATIPDD QIRGNLRIGA
VVEAKHPEKK EFAEATITKI QDCSQYTVVF DDGDITTLRR TALCLKSGRH FAESDTLDQL
PLTHPEHFSN PVIGGRRGRR RLDENSEDEE LLLISGAELE DEREEHIGRV VCVEGSEKKK
QKDNWFPGLV VAPTAQDNVP IHVKEEYLVR SFKDGRYYTV PKKEANEFTR EVGARVEHPT
LKAAVDKALL YLDCNELPPH WDRDLLLYGL GDVASTDNDA GLDYESSDDE PREEKDHFVA
QLYKFMDDSG TPINKGPTIG TRDVDLYKLF KVVQNQGGYN RVTNHNNWKL VALKMGFGQN
PITVNLVKIA YKKFLFTFEE FYRKLGCTLL NHPSRLSRSC CRGGRNLIRN KDSGNSSSSL
TKTDTKRQVK EGKNLSDLNL VTGKIKVEKD EYSSQSQAQD EELYVEIPSD GVSKSPTPPP
STSATTAVTQ RTKRNTTAVG APGGSNVASP QSPTLKVHLP IKIKVEQNEC SQTTLSPVQT
PTTPPLTPPL PPRSGSLSPT QPAAIPQQQQ QHSFLQISRP ISPDTPALLA QAVSTPQLTS
PQQQSPTAQK KEPRARQLKK STTVENIATL SSNITKDLDN IAATELESNV QIPQMKEKKR
RAAFPRAVVA AKKVKQQHTP RITSPHTPGL AASRTKRAVN KDKLRTIVKN LKNKWVPASS
SVPGTNNQEL TKVAVKTKTP KDDNIANIKS RRDDAQLHNI VSTDEKRKGG RKRRDKRLSE
DRFVPLPSYK TILPGDKLRV YYGPTLESKV TYEAKVLSIR TEGSESVYLV HYTGWNNRYD
EWIKTSRIAD NLSWIPGRSA RKANQTPKTP KRKGNHKNET GGFSVKDNQQ PSMTPTPTSS
SASSTSSNSS TIMSKSNVTS LMSSGCRKTS TRASTRAAAS RKEIPTTESN TENDSDTNTE
SEVFKKSVME SKSNHESDKK SFVKKRKFEE ISKTDPDLPI KLEIGDSDEE SINNSRNAEN
IDNDENTDEH DMKIIKSEII KKEAVSENES NNINSNGGDN LGNVIIVDVE LKNESEEDSL
VIDENQEIDE SEVIEGYSSV ASTDSKPDSK LHPTNQTGRD FDLTQIRSEL KGIETNVTRP
DDIEDLNLEE SNTLDIYEFK EPEFDTTTTS KMEDKNKGRS NIVVRMFSDV INNVTNNQRE
MKCNEPRIDL DESNNTTAAT TYSVQNTSGD TLSDERPILK TCEEAFDRVC AEPLRAATER
PPAGFLFMDE EEDEEDIYDD DDSQDRLIIS ERDSDNEIPA EVSIDLAPAD LNEHSTTIQK
EELESKSITT LDAECEKEVI SREDDEEDLE DELLNVAIQR AIESSEDTTD GEILSRHLAP
RHMFAADTFS PVLDVDSNKI QNDNDTDSII KISMLPTNHH ESPASTEDAI KETNRTTSGE
SQLLQQNSAL DLSNASEEIQ SDSVELLTQD EEMICEDEMA SQEDAGEPET VIDTLDIESN
VGALGEDEDE EEDDLIAVED LASSQGGLPS SHGDLANAGG GNSSGGGGSG GSTRGPHTPP
GPAPGTPPDT ELDEDYTEQY NANAVIDDQY EEVADQEVDR DEQPPLLTRE VDVEEETVVR
QEVDEEEIAC NDEENDETNL VSLLCEETIP GSPQVAVTSD SYQLSPGTND EESINFNEVT
ISKELQDNMA DKDMKEKDDQ VFVGNIVESG ANNTNNDHQQ IDETIHNATT NSCRNLQQNV
QQQVNQTPIP SPSSSLSSNN SPTREALQSP QNEVIQSQAS GSNEQYQQLC PTVQASTSDE
IAKPSVNESI RTRKSDTRSA SGKKSRRTRK RSEEVAKRKY RSRHHASDSD DHCENTNRGY
HQGRSRTPPR LRKYNFTVQM SPEMDHNQRV NKIQNAMGDI RKAYASLKLE LASIERRRKK
LRRREREFRL


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Kits Elisa; taq POLYMERASE

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Pathways :
WP1038: Vitamin A and carotenoid metabolism
WP1155: Vitamin A and carotenoid metabolism
WP1259: Retinol metabolism
WP1297: Retinol metabolism
WP142: mRNA processing
WP1531: Vitamin D synthesis
WP1581: Histidine metabolism
WP1616: ABC transporters
WP1624: Bacterial secretion system
WP1673: Naphthalene and anthracene degradation
WP1689: Porphyrin and chlorophyll metabolism
WP1692: Protein export
WP1700: Selenoamino acid metabolism
WP1709: Thiamine metabolism
WP1714: Tyrosine metabolism
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP1825: GPCR ligand binding
WP1869: Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP1899: Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
WP2003: Leukocyte TarBase
WP2292: Chemokine signaling pathway
WP590: Cardiovascular Signaling
WP716: Vitamin A and carotenoid metabolism
WP731: Sterol regulatory element binding protein related
WP805: Retinol metabolism (BiGCaT, NuGO)

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[ARID4B BRCAA1 RBBP1L1 RBP1L1 SAP180] AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)
[Arid4a Rbbp1 Rbp1] AT-rich interactive domain-containing protein 4A (ARID domain-containing protein 4A) (Retinoblastoma-binding protein 1)
[STRA6 PP14296 UNQ3126/PRO10282/PRO19578] Receptor for retinol uptake STRA6 (Retinol-binding protein receptor STRA6) (Stimulated by retinoic acid gene 6 protein homolog)
[Stra6] Receptor for retinol uptake STRA6 (Retinoic acid-responsive protein) (Retinol-binding protein receptor STRA6) (Stimulated by retinoic acid gene 6 protein)
[STRA6] Receptor for retinol uptake STRA6 (Retinol-binding protein receptor STRA6) (Stimulated by retinoic acid gene 6 protein homolog)
[KDM5A JARID1A RBBP2 RBP2] Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)
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[HABP4] Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Hyaluronan-binding protein 4) (Ki-1/57 intracellular antigen)
[SPN1 IWS1 YPR133C] Transcription factor SPN1 (Interacts with SPT6 protein 1) (Suppresses postrecruitment functions protein 1)
[Habp4] Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Hyaluronic acid-binding protein 4)
[Cytb] Cytochrome b (Fragment)
[RB1] Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)
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[SRV2 CAP1 YNL138W N1210 N1838] Adenylyl cyclase-associated protein (CAP)
[RSP5 MDP1 NPI1 YER125W SYGP-ORF41] E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
[LSM7 YNL147W N1202 N1780] U6 snRNA-associated Sm-like protein LSm7
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[App] Amyloid-beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99) (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (APP-C59) (Amyloid intracellular domain 59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (APP-C57) (Amyloid intracellular domain 57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AID(50)) (Gamma-CTF(50)); C31]
[APP] Amyloid-beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloid-beta precursor protein) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Gamma-CTF(50)); C31]
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[APP] Amyloid-beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloid-beta precursor protein) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Gamma-CTF(50)); C31]

Bibliography :