GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); mRNA guanylyltransferase (EC 2.7.7.-); GDP polyribonucleotidyltransferase (EC 2.7.7.88)]

 Q4KRW1_HRSV             Unreviewed;      2165 AA.
Q4KRW1;
02-AUG-2005, integrated into UniProtKB/TrEMBL.
02-AUG-2005, sequence version 1.
16-JAN-2019, entry version 86.
RecName: Full=RNA-directed RNA polymerase L {ECO:0000256|PIRNR:PIRNR000830};
Short=Protein L {ECO:0000256|PIRNR:PIRNR000830};
AltName: Full=Large structural protein {ECO:0000256|PIRNR:PIRNR000830};
AltName: Full=Replicase {ECO:0000256|PIRNR:PIRNR000830};
AltName: Full=Transcriptase {ECO:0000256|PIRNR:PIRNR000830};
Includes:
RecName: Full=RNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR000830};
EC=2.7.7.48 {ECO:0000256|PIRNR:PIRNR000830};
Includes:
RecName: Full=mRNA (guanine-N(7)-)-methyltransferase {ECO:0000256|PIRNR:PIRNR000830};
EC=2.1.1.56 {ECO:0000256|PIRNR:PIRNR000830};
Includes:
RecName: Full=mRNA guanylyltransferase {ECO:0000256|PIRNR:PIRNR000830};
EC=2.7.7.- {ECO:0000256|PIRNR:PIRNR000830};
Includes:
RecName: Full=GDP polyribonucleotidyltransferase {ECO:0000256|PIRNR:PIRNR000830};
EC=2.7.7.88 {ECO:0000256|PIRNR:PIRNR000830};
Name=L {ECO:0000313|EMBL:AAX23996.1};
Human respiratory syncytial virus.
Viruses; ssRNA viruses; ssRNA negative-strand viruses;
Mononegavirales; Pneumoviridae; Orthopneumovirus.
NCBI_TaxID=11250 {ECO:0000313|EMBL:AAX23996.1, ECO:0000313|Proteomes:UP000158141};
NCBI_TaxID=9606; Homo sapiens (Human).
[1] {ECO:0000313|EMBL:AAX23996.1, ECO:0000313|Proteomes:UP000158141}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-26 {ECO:0000313|EMBL:AAX23996.1};
PubMed=15994826; DOI=10.1128/JVI.79.14.9315-9319.2005;
Lo M.S., Brazas R.M., Holtzman M.J.;
"Respiratory syncytial virus nonstructural proteins NS1 and NS2
mediate inhibition of Stat2 expression and alpha/beta interferon
responsiveness.";
J. Virol. 79:9315-9319(2005).
[2] {ECO:0000313|Proteomes:UP000119304, ECO:0000313|Proteomes:UP000130886, ECO:0000313|Proteomes:UP000163705}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Long {ECO:0000313|EMBL:AHC94766.1},
Luc_recombinant_long {ECO:0000313|EMBL:AHC94778.1}, and
MCh_recombinant_long {ECO:0000313|EMBL:AHC94790.1};
Rameix-Welti M.-A., Sourimant J., Yu Q., Ribeiro C., Galloux M.,
Fix J., Gault E., Eleouet J.-F.;
"Rescue of respiratory syncytial virus expressing mCherry and firefly
luciferase : new tools for antiviral drug discovery.";
Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:AMQ35404.1, ECO:0000313|Proteomes:UP000103294}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Long recombinant {ECO:0000313|EMBL:AMQ35404.1};
Wen L., He K., Yang H.;
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:AMQ35404.1, ECO:0000313|Proteomes:UP000103294}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Long recombinant {ECO:0000313|EMBL:AMQ35404.1};
Zhivaki D., Lemoine S., Lim A., Morva A., Vidalain P.-O.,
Schandene L., Casartelli N., Rameix - Welti M.A.--A., Deriaud E.,
Beitz B., Ripaux - Lefevre M., Miatello J., Lemercier B., Descamps D.,
Eleouet J.F.--F., Riffault S., Schwartz O., Porcheray F., Mascart F.,
Zhang X., Tissieres P., Lo - Man R.;
"Neonatal regulatory B cells are infected by human respiratory
syncytial virus and are predictive ofacute bronchiolitis severity.";
Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
[5] {ECO:0000313|EMBL:API65192.1}
NUCLEOTIDE SEQUENCE.
Rincheval V., Lelek M., Bouillier C., Sitterlin D., Blouquit S.,
Galloux M., Eleouet J.-F., Zimmer C., Gault E., Rameix-Welti M.-A.;
"M2-1 protein of respiratory syncytial virus concentrates with mRNA in
viral mRNA granules inside inclusion bodies.";
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Displays RNA-directed RNA polymerase, mRNA guanylyl
transferase, mRNA (guanine-N(7)-)-methyltransferase and poly(A)
synthetase activities. The viral mRNA guanylyl transferase
displays a different biochemical reaction than the cellular
enzyme. The template is composed of the viral RNA tightly
encapsidated by the nucleoprotein (N). Functions either as
transcriptase or as replicase. The transcriptase synthesizes
subsequently the subgenomic RNAs, assuring their capping and
polyadenylation by a stuttering mechanism. The replicase mode is
dependent on intracellular protein N concentration. In this mode,
the polymerase replicates the whole viral genome without
recognizing the transcriptional signals.
{ECO:0000256|PIRNR:PIRNR000830}.
-!- CATALYTIC ACTIVITY:
Reaction=a 5'-(5'-triphosphoguanosine)-(purine-ribonucleotide)-
[mRNA] + S-adenosyl-L-methionine = a 5'-(N(7)-methyl 5'-
triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-
adenosyl-L-homocysteine; Xref=Rhea:RHEA:11220, Rhea:RHEA-
COMP:12925, Rhea:RHEA-COMP:13407, ChEBI:CHEBI:57856,
ChEBI:CHEBI:59789, ChEBI:CHEBI:133968, ChEBI:CHEBI:136896;
EC=2.1.1.56; Evidence={ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS01117443};
-!- CATALYTIC ACTIVITY:
Reaction=a 5'-triphospho-(purine-ribonucleotide)-[mRNA] + GDP +
H(+) = a 5'-(5'-triphosphoguanosine)-(purine-ribonucleotide)-
[mRNA] + diphosphate; Xref=Rhea:RHEA:46292, Rhea:RHEA-
COMP:13407, Rhea:RHEA-COMP:13942, ChEBI:CHEBI:15378,
ChEBI:CHEBI:33019, ChEBI:CHEBI:58189, ChEBI:CHEBI:136896,
ChEBI:CHEBI:138288; EC=2.7.7.88;
Evidence={ECO:0000256|PIRNR:PIRNR000830};
-!- CATALYTIC ACTIVITY:
Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557,
ChEBI:CHEBI:83400; Evidence={ECO:0000256|PIRNR:PIRNR000830};
-!- SUBCELLULAR LOCATION: Host cytoplasm
{ECO:0000256|PIRNR:PIRNR000830, ECO:0000256|SAAS:SAAS00847043}.
Virion {ECO:0000256|PIRNR:PIRNR000830}.
-!- SIMILARITY: Belongs to the paramyxovirus L protein family.
{ECO:0000256|PIRNR:PIRNR000830}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AY911262; AAX23996.1; -; Genomic_RNA.
EMBL; KF713490; AHC94766.1; -; Viral_cRNA.
EMBL; KF713491; AHC94778.1; -; Viral_cRNA.
EMBL; KF713492; AHC94790.1; -; Viral_cRNA.
EMBL; KU707921; AMQ35404.1; -; Genomic_RNA.
EMBL; KX348546; API65192.1; -; Genomic_RNA.
Proteomes; UP000103294; Genome.
Proteomes; UP000119304; Genome.
Proteomes; UP000130886; Genome.
Proteomes; UP000158141; Genome.
Proteomes; UP000163705; Genome.
GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0004482; F:mRNA (guanine-N7-)-methyltransferase activity; IEA:UniProtKB-EC.
GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
InterPro; IPR039736; L_poly_C.
InterPro; IPR026890; Mononeg_mRNAcap.
InterPro; IPR014023; Mononeg_RNA_pol_cat.
InterPro; IPR025786; Mononega_L_MeTrfase.
InterPro; IPR016269; RNA-dir_pol_paramyxovirus.
Pfam; PF14318; Mononeg_mRNAcap; 1.
Pfam; PF00946; Mononeg_RNA_pol; 1.
PIRSF; PIRSF000830; RNA_pol_ParamyxoV; 3.
TIGRFAMs; TIGR04198; paramyx_RNAcap; 1.
PROSITE; PS50526; RDRP_SSRNA_NEG_NONSEG; 1.
PROSITE; PS51590; SAM_MT_MNV_L; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503432};
Complete proteome {ECO:0000313|Proteomes:UP000103294,
ECO:0000313|Proteomes:UP000119304, ECO:0000313|Proteomes:UP000130886,
ECO:0000313|Proteomes:UP000158141};
Host cytoplasm {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00847045};
Methyltransferase {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00847038};
mRNA capping {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503423};
mRNA processing {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503423};
Multifunctional enzyme {ECO:0000256|SAAS:SAAS00503427};
Nucleotide-binding {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503432};
Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503441, ECO:0000313|EMBL:AMQ35404.1};
RNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503441, ECO:0000313|EMBL:AMQ35404.1};
S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503438};
Transferase {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503441, ECO:0000256|SAAS:SAAS00847038,
ECO:0000313|EMBL:AMQ35404.1};
Viral RNA replication {ECO:0000256|PIRNR:PIRNR000830,
ECO:0000256|SAAS:SAAS00503417};
Virion {ECO:0000256|PIRNR:PIRNR000830, ECO:0000256|SAAS:SAAS00847034}.
DOMAIN 693 877 RdRp catalytic.
{ECO:0000259|PROSITE:PS50526}.
DOMAIN 1820 2008 Mononegavirus-type SAM-dependent 2'-O-
MTase. {ECO:0000259|PROSITE:PS51590}.
SEQUENCE 2165 AA; 250415 MW; F085876F9C9CED3A CRC64;
MDPIINGNSA NVYLTDSYLK GVISFSECNA LGSYIFNGPY LKNDYTNLIS RQNPLIEHMN
LKKLNITQSL ISKYHKGEIK LEEPTYFQSL LMTYKSMTSL EQIATTNLLK KIIRRAIEIS
DVKVYAILNK LGLKEKDKIK SNNGQDEDNS VITTIIKDDI LSAVKDNQSH LKADKNHSTK
QKDTIKTTLL KKLMCSMQHP PSWLIHWFNL YTKLNNILTQ YRSNEVKNHG FILIDNQTLS
GFQFILNQYG CIVYHKELKR ITVTTYNQFL TWKDISLSRL NVCLITWISN CLNTLNKSLG
LRCGFNNVIL TQLFLYGDCI LKLFHNEGFY IIKEVEGFIM SLILNITEED QFRKRFYNSM
LNNITDAANK AQKNLLSRVC HTLLDKTVSD NIINGRWIIL LSKFLKLIKL AGDNNLNNLS
ELYFLFRIFG HPMVDERQAM DAVKVNCNET KFYLLSSLSM LRGAFIYRII KGFVNNYNRW
PTLRNAIVLP LRWLTYYKLN TYPSLLELTE RDLIVLSGLR FYREFRLPKK VDLEMIINDK
AISPPKNLIW TSFPRNYMPS HIQNYIEHEK LKFSESDKSR RVLEYYLRDN KFNECDLYNC
VVNQSYLNNP NHVVSLTGKE RELSVGRMFA MQPGMFRQVQ ILAEKMIAEN ILQFFPESLT
RYGDLELQKI LELKAGISNK SNRYNDNYNN YISKCSIITD LSKFNQAFRY ETSCICSDVL
DELHGVQSLF SWLHLTIPHV TIICTYRHAP PYIRDHIVDL NNVDEQSGLY RYHMGGIEGW
CQKLWTIEAI SLLDLISLKG KFSITALING DNQSIDISKP VRLMEGQTHA QADYLLALNS
LKLLYKEYAG IGHKLKGTET YISRDMQFMS KTIQHNGVYY PASIKKVLRV GPWINTILDD
FKVSLESIGS LTQELEYRGE SLLCSLIFRN VWLYNQIALQ LKNHALCNNK LYLDILKVLK
HLKTFFNLDN IDTALTLYMN LPMLFGGGDP NLLYRSFYRR TPDFLTEAIV HSVFILSYYT
NHDLKDKLQD LSDDRLNKFL TCIITFDKNP NAEFVTLMRD PQALGSERQA KITSEINRLA
VTEVLSTAPN KIFSKSAQHY TTTEIDLNDI MQNIEPTYPH GLRVVYESLP FYKAEKIVNL
ISGTKSITNI LEKTSAIDLT DIDRATEMMR KNITLLIRIL PLDCNRDKRE ILSMENLSIT
ELSKYVRERS WSLSNIVGVT SPSIMYTMDI KYTTSTIASG IIIEKYNVNS LTRGERGPTK
PWVGSSTQEK KTMPVYNRQV LTKKQRDQID LLAKLDWVYA SIDNKDEFME ELSIGTLGLT
YEKAKKLFPQ YLSVNYLHRL TVSSRPCEFP ASIPAYRTTN YHFDTSPINR ILTEKYGDED
IDIVFQNCIS FGLSLMSVVE QFTNVCPNRI ILIPKLNEIH LMKPPIFTGD VDIHKLKQVI
QKQHMFLPDK ISLTQYVELF LSNKTLKSGS HVNSNLILAH KISDYFHNTY ILSTNLAGHW
ILIIQLMKDS KGIFEKDWGE GYITDHMFIN LKVFFNAYKT YLLCFHKGYG KAKLECDMNT
SDLLCVLELI DSSYWKSMSK VFLEQKVIKY ILSQDASLHR VKGCHSFKLW FLKRLNVAEF
TVCPWVVNID YHPTHMKAIL TYIDLVRMGL INIDRIHIKN KHKFNDEFYT SNLFYINYNF
SDNTHLLTKH IRIANSELEN NYNKLYHPTP ETLENILANP IKSNDKKTLN DYCIGKNVDS
IMLPLLSNKK LVKSSAMIRT NYSKQDLYNL FPTVVIDRII DHSGNTAKSN QLYTTTSHQI
SLVHNSTSLY CMLPWHHINR FNFVFSSTGC KISIEYILKD LKIKDPNCIA FIGEGAGNLL
LRTVVELHPD IRYIYRSLKD CNDHSLPIEF LRLYNGHINI DYGENLTIPA TDATNNIHWS
YLHIKFAEPI SLFVCDAELP VTVNWSKIII EWSKHVRKCK YCSSVNKCTL IVKYHAQDDI
DFKLDNITIL KTYVCLGSKL KGSEVYLVLT IGPANIFPVF NVVQNAKLIL SRTKNFIMPK
KADKESIDAN IKSLIPFLCY PITKKGINTA LSKLKSVVSG DILSYSIAGR NEVFSNKLIN
HKHMNILKWF NHVLNFRSTE LNYNHLYMVE STYPYLSELL NSLTTNELKK LIKITGSLLY
NFHNE


Related products :

Catalog number Product name Quantity
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 1 mg
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 0.1 mg
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 0.5 mg
20-372-60269 polymerase (RNA) II (DNA directed) polypeptide F (POLR2F). mRNA - Mouse monoclonal anti-human POLR2F antibody; RNA polymerases I. II. and III subunit ABC2; DNA-directed RNA polymerase II subunit F; RP 0.1 mg
EIAAB35792 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Homo sapiens,Human,POLR2B,RNA polymerase II subunit 2,RNA polyme
EIAAB35812 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Homo sapiens,Human,POLR3B,RNA polymerase III subunit C
EIAAB35794 A-152E5.7,DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Homo sapiens,Human,POLR2C,RNA polymerase II subunit 3,R
EIAAB35793 DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Mouse,Mus musculus,Polr2c,RNA polymerase II subunit 3,RNA polymer
EIAAB35791 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Mouse,Mus musculus,Polr2b,RNA polymerase II subunit 2,RNA polyme
EIAAB35813 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Mouse,Mus musculus,Polr3b,RNA polymerase III subunit C
EIAAB35785 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Mouse,Mus musculus,Polr2a,RNA polymerase II subunit B1,Rpii215,Rpo2
EIAAB35736 A190,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Homo sapiens,Human,POLR1A,RNA polymerase I 194 kDa subunit,RNA pol
EIAAB35784 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Homo sapiens,Human,POLR2,POLR2A,RNA polymerase II subunit B1,RNA-di
EIAAB35735 A194,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Polr1a,Rat,Rattus norvegicus,RNA polymerase I 194 kDa subunit,RNA
EIAAB35808 DNA-directed RNA polymerase III largest subunit,DNA-directed RNA polymerase III subunit A,DNA-directed RNA polymerase III subunit RPC1,Homo sapiens,Human,POLR3A,RNA polymerase III 155 kDa subunit,RNA
EIAAB35737 DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Mouse,Mus musculus,Polr1a,RNA polymerase I 194 kDa subunit,RNA polymera
60269 IgG,polymerase (RNA) II (DNA directed) polypeptide F (POLR2F), mRNA 0.1 mg
20-372-60270 polymerase (RNA) II (DNA directed) polypeptide G (POLR2G) - Mouse monoclonal anti-human POLR2G antibody; RNA polymerase II subunit B7; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polyme 0.1 mg
GWB-9FF90B polymerase (RNA) II (DNA directed) polypeptide F (POLR2F) mRNA, Antibody
EIAAB35820 BN51,BN51T,DNA-directed RNA polymerase III subunit D,DNA-directed RNA polymerase III subunit RPC4,Homo sapiens,Human,POLR3D,Protein BN51,RNA polymerase III 47 kDa subunit,RNA polymerase III subunit C4
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 1 mg
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 0.5 mg
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 0.1 mg
EIAAB35832 Bos taurus,Bovine,DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide,DNA-directed RNA polymerase III subunit H,DNA-directed RNA polymerase III subunit RPC8,POLR3H,RNA polymerase III subunit
EIAAB35750 DNA-directed RNA polymerase I subunit E,DNA-directed RNA polymerase I subunit RPA49,Homo sapiens,Human,PAF53,POLR1E,PRAF1,RNA polymerase I subunit A49,RNA polymerase I-associated factor 1,RNA polymera

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Pathways :
WP1438: Influenza A virus infection
WP1644: DNA replication
WP1663: Homologous recombination
WP1672: Mismatch repair
WP1693: Purine metabolism
WP1694: Pyrimidine metabolism
WP2218: sGC
WP1673: Naphthalene and anthracene degradation
WP1700: Selenoamino acid metabolism
WP1714: Tyrosine metabolism
WP2292: Chemokine signaling pathway
WP1023: mRNA processing
WP1049: G Protein Signaling Pathways
WP1142: mRNA processing
WP1165: G Protein Signaling Pathways
WP1229: mRNA processing
WP123: mRNA processing
WP1371: G Protein Signaling Pathways
WP142: mRNA processing
WP1493: Carbon assimilation C4 pathway
WP1502: Mitochondrial biogenesis
WP1531: Vitamin D synthesis
WP1566: Citrate cycle (TCA cycle)
WP1613: 1,4-Dichlorobenzene degradation
WP1616: ABC transporters

Related Genes :
[L] Large structural protein (Protein L) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] Large structural protein (Protein L) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] Large structural protein (Protein L) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); mRNA guanylyltransferase (EC 2.7.7.-); GDP polyribonucleotidyltransferase (EC 2.7.7.88)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM (Precursor membrane protein); Peptide pr (Peptide precursor); Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Non-structural protein 2A-alpha (NS2A-alpha); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (NS5)] (Fragment)
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]
[GP1 MZ11_60484gpGP1 MZ11_60553gpGP1] Genome polyprotein [Cleaved into: Peptide 2k; Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (NS5)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[L] RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56); GDP polyribonucleotidyltransferase (EC 2.7.7.88); Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296)]
[] Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)]

Bibliography :
No related Items