GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Rat Axl shortform

 Q8VI99_RAT              Unreviewed;       879 AA.
Q8VI99;
01-MAR-2002, integrated into UniProtKB/TrEMBL.
01-MAR-2002, sequence version 1.
16-JAN-2019, entry version 137.
SubName: Full=Rat Axl shortform {ECO:0000313|EMBL:BAB84128.1};
Name=Axl {ECO:0000313|RGD:620028};
Synonyms=axl {ECO:0000313|EMBL:BAB84128.1};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116 {ECO:0000313|EMBL:BAB84128.1};
[1] {ECO:0000313|EMBL:BAB84128.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Wistar {ECO:0000313|EMBL:BAB84128.1};
Yonemasu T., Funakoshi H., Nakano T., Matsumoto K., Nakamura T.;
"Identification of Gas6, a putative ligand for Sky and Axl receptor
tyrosine kinases, as a novel neurotrophic factor for hippocampal
neurons.";
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
-!- CATALYTIC ACTIVITY:
Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-
tyrosyl-[protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136,
Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
ChEBI:CHEBI:46858, ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
EC=2.7.10.1; Evidence={ECO:0000256|SAAS:SAAS01124082};
-!- SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein
kinase family. {ECO:0000256|SAAS:SAAS00941529}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AB067527; BAB84128.1; -; Genomic_DNA.
PIR; PT0189; PT0189.
RefSeq; NP_001013165.1; NM_001013147.1.
UniGene; Rn.161805; -.
ProteinModelPortal; Q8VI99; -.
GeneID; 308444; -.
KEGG; rno:308444; -.
CTD; 558; -.
RGD; 620028; Axl.
eggNOG; ENOG410IG6I; Eukaryota.
eggNOG; COG0515; LUCA.
HOGENOM; HOG000231685; -.
HOVERGEN; HBG006346; -.
KO; K05115; -.
OrthoDB; 263089at2759; -.
Genevisible; Q8VI99; RN.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0043235; C:receptor complex; IBA:GO_Central.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0019838; F:growth factor binding; TAS:RGD.
GO; GO:0032036; F:myosin heavy chain binding; IPI:RGD.
GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.
GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IBA:GO_Central.
GO; GO:0017147; F:Wnt-protein binding; IBA:GO_Central.
GO; GO:0031100; P:animal organ regeneration; IEP:RGD.
GO; GO:0030154; P:cell differentiation; IMP:RGD.
GO; GO:0016477; P:cell migration; IBA:GO_Central.
GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:RGD.
GO; GO:0001779; P:natural killer cell differentiation; IBA:GO_Central.
GO; GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.
GO; GO:0007399; P:nervous system development; IBA:GO_Central.
GO; GO:0006909; P:phagocytosis; IBA:GO_Central.
GO; GO:0030168; P:platelet activation; IBA:GO_Central.
GO; GO:0051897; P:positive regulation of protein kinase B signaling; IBA:GO_Central.
GO; GO:0042246; P:tissue regeneration; TAS:RGD.
GO; GO:0048771; P:tissue remodeling; TAS:RGD.
GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
GO; GO:0016055; P:Wnt signaling pathway; IBA:GO_Central.
CDD; cd00063; FN3; 2.
Gene3D; 2.60.40.10; -; 4.
InterPro; IPR003961; FN3_dom.
InterPro; IPR036116; FN3_sf.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR011009; Kinase-like_dom_sf.
InterPro; IPR000719; Prot_kinase_dom.
InterPro; IPR017441; Protein_kinase_ATP_BS.
InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
InterPro; IPR008266; Tyr_kinase_AS.
InterPro; IPR020635; Tyr_kinase_cat_dom.
Pfam; PF00041; fn3; 2.
Pfam; PF07714; Pkinase_Tyr; 1.
PRINTS; PR00109; TYRKINASE.
SMART; SM00060; FN3; 2.
SMART; SM00409; IG; 2.
SMART; SM00219; TyrKc; 1.
SUPFAM; SSF48726; SSF48726; 2.
SUPFAM; SSF49265; SSF49265; 1.
SUPFAM; SSF56112; SSF56112; 1.
PROSITE; PS50853; FN3; 2.
PROSITE; PS50835; IG_LIKE; 2.
PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|SAAS:SAAS00708816};
Disulfide bond {ECO:0000256|SAAS:SAAS00916669};
Immunoglobulin domain {ECO:0000256|SAAS:SAAS00941986};
Kinase {ECO:0000256|SAAS:SAAS00582553};
Membrane {ECO:0000256|SAAS:SAAS00602683, ECO:0000256|SAM:Phobius};
Nucleotide-binding {ECO:0000256|SAAS:SAAS00708816};
Receptor {ECO:0000256|SAAS:SAAS00600436};
Signal {ECO:0000256|SAM:SignalP};
Transferase {ECO:0000256|SAAS:SAAS00582553};
Transmembrane {ECO:0000256|SAAS:SAAS00602683,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00602683,
ECO:0000256|SAM:Phobius};
Tyrosine-protein kinase {ECO:0000256|SAAS:SAAS00582553}.
SIGNAL 1 20 {ECO:0000256|SAM:SignalP}.
CHAIN 21 879 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5004315144.
TRANSMEM 435 457 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 20 122 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 133 216 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 221 325 Fibronectin type-III.
{ECO:0000259|PROSITE:PS50853}.
DOMAIN 330 422 Fibronectin type-III.
{ECO:0000259|PROSITE:PS50853}.
DOMAIN 521 792 Protein kinase.
{ECO:0000259|PROSITE:PS50011}.
SEQUENCE 879 AA; 97221 MW; D2EEB23304424644 CRC64;
MGRVPLAWCV ALCCWGCAAP KDTQTEADSP FVGNPGNITG ARGLTGTLRC ELQVQGEPPE
VMWLRDGQIL ELADNTQTQV PLGEDWQDEW KVVSQLRISA LQLSDAGEYQ CMVHLEGRTF
VSQPGFVGLE GLPYFLEEPE DKAVPANTPF NLSCQAQGPP EPVTLLWLQD AVPLAPVAGY
SFQHSLQAPG LNKTSSFSCE AHNAKGVTTS RTATITVLPQ RPHNLHVVSR HPTELEVAWI
PTLSGIYPLT HCTLQAVLSN DGVGVWLGKS DPPEEPLTVQ VSVPPHQLRL EKLLPHTPYH
IRVSCTSSQG PSPWTHWLPV ETTEGVPLGP PENVSAMRNG SQALVRWQEP REPLQGTLLG
YRLAYRGQDT PEVLMDIGLT REVTLELRGD RPVANLTVSV AAYTSAGDGP WSLPVPLEPW
RPVSEPPPPA FSWPWWYVLL GALVAAACVL ILTLFLVHRR KKETRYGEVF EPTVERGELV
VRYRARKSYS RRTTEATLNS LGISEELKEK LRDVMVDRHK VALGKTLGEG EFGAVMEGQL
NQDDSILKVA VKTMKIAICT RSELEDFLSE AVCMKEFDHP NVMRLIGVCF QGSDREGFPE
PVVILPFMKH GDLHSFLLYS RLGDQPVFLP TQMLVKFMAD IASGMEYLST KRFIHRDLAA
RNCMLNENMS VCVADFGLSK KIYNGDYYRQ GRIAKMPVKW IAIESLADRV YTSKSDVWSF
GVTMWEIATR GQTPYPGVEN SEIYDYLRQG NRLKQPLDCL DGLYALMSRC WELNPRDRPS
FAELREDLEN TLKALPPAQE PDEILYVNMD EGGSHLEPRG AAGGADPPTQ PDPKDYCSCL
TAADVHSAGR YVLCPSTAPG PTLSADRGCP APPGQEDGA


Related products :

Catalog number Product name Quantity

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Pathways :
No related Items

Related Genes :
[Axl axl] Rat Axl shortform
[Axl axl] Rat Axl longform
[Gas6] Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) (Growth-potentiating factor) (GPF)
[Axl] Axl receptor tyrosine kinase
[] Major urinary protein (MUP) (Allergen Rat n I) (Alpha(2)-euglobulin) (Alpha-2u-globulin) (alpha-2u globulin PGCL1) (allergen Rat n 1) [Cleaved into: 15.5 kDa fatty acid-binding protein (15.5 kDa FABP)]
[Axl] Axl receptor tyrosine kinase
[AXL UFO] Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
[Axl] Axl receptor tyrosine kinase
[Cacna1c Cach2 Cacn2 Cacnl1a1 Cchl1a1] Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Rat brain class C) (RBC) (Voltage-gated calcium channel subunit alpha Cav1.2)
[Cacna1d Cach3 Cacn4 Cacnl1a2 Cchl1a2] Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)
[Cacna1a Cach4 Cacn3 Cacnl1a4] Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide, isoform 4) (Rat brain class A) (RBA-I) (Voltage-gated calcium channel subunit alpha Cav2.1)
[Plpp3 Lpp3 Ppap2b] Phospholipid phosphatase 3 (EC 3.1.3.4) (Differentially expressed in rat intestine 42) (Dri42) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b)
[Ehmt2 Apom Bat4 Bat8 C2 C4a Cfb Csnk2b G7e Hspa1a Hspa1b Hspa1l Ly6g5c Ly6g6c Neu1 Ng35 Rps25-ps2 Stk19] Euchromatic histone lysine methyltransferase 2 (HLA-B associated transcript 8, rat orthologue)
[Adgrg2 Gpr64 Re6] Adhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Rat epididymis-specific protein 6) (Re6)
[AXL1 YPR122W P9642.4] Putative protease AXL1 (EC 3.4.24.-)
[GAS6 AXLLG] Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
[Tmprss11d Rat] Transmembrane protease serine 11D (EC 3.4.21.-) (Adrenal secretory serine protease) (AsP) (Airway trypsin-like protease) (AT) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain]
[AXL CK820_G0030505] AXL isoform 1 (AXL receptor tyrosine kinase)
[Axl Ark Ufo] Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (Adhesion-related kinase)
[AXL2 BUD10 SRO4 YIL140W] Axial budding pattern protein 2 (Bud site selection protein 10) (Suppressor of RHO3 protein 4)
[Grb2 Ash] Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
[AXL GW7_15448] Tyrosine-protein kinase receptor UFO (Tyrosine-protein kinase receptor UFO isoform 1)
[Ncdn] Neurochondrin (Neurite outgrowth-related protein from the rat brain) (Norbin)
[AXL] AXL receptor tyrosine kinase
[AXL] AXL receptor tyrosine kinase
[Tnk2 Ack1] Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
[AXL1 AXL At2g32410] NEDD8-activating enzyme E1 regulatory subunit AXL (Protein AXR1-LIKE) (Protein AXR1-LIKE 1)
[Gas6] Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
[Plcg1] 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
[Tyro3 Sky] Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase SKY)

Bibliography :
?>