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S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)

 SKP1_MOUSE              Reviewed;         163 AA.
Q9WTX5; Q8C5H6;
11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 3.
02-JUN-2021, entry version 168.
RecName: Full=S-phase kinase-associated protein 1;
AltName: Full=Cyclin-A/CDK2-associated protein p19;
AltName: Full=S-phase kinase-associated protein 1A;
AltName: Full=p19A;
AltName: Full=p19skp1;
Name=Skp1 {ECO:0000303|PubMed:10097128, ECO:0000312|MGI:MGI:103575};
Synonyms=Skp1a {ECO:0000312|MGI:MGI:103575};
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND IDENTIFICATION IN A COMPLEX WITH
CUL1; PHOSPHORYLATED NFKBIA AND BTRC.
STRAIN=C57BL/6J;
PubMed=10097128; DOI=10.1073/pnas.96.7.3859;
Hatakeyama S., Kitagawa M., Nakayama K., Shirane M., Matsumoto M.,
Hattori K., Higashi H., Nakano H., Okumura K., Onoe K., Good R.A.,
Nakayama K.;
"Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin
ligase Skp1/Cul 1/F-box protein FWD1.";
Proc. Natl. Acad. Sci. U.S.A. 96:3859-3863(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J, and NOD;
TISSUE=Brain, Head, Kidney, Olfactory bulb, and Thymus;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N; TISSUE=Mammary tumor;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project:
the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
FUNCTION, AND IDENTIFICATION IN A COMPLEX WITH PHOSPHORYLATED NFKBIA; BTRC
AND RELA.
PubMed=9990853; DOI=10.1101/gad.13.3.284;
Spencer E., Jiang J., Chen Z.J.;
"Signal-induced ubiquitination of IkappaBalpha by the F-box protein
Slimb/beta-TrCP.";
Genes Dev. 13:284-294(1999).
[5]
IDENTIFICATION IN A COMPLEX WITH BTRC AND CUL1.
PubMed=11735228; DOI=10.1006/geno.2001.6658;
Maruyama S., Hatakeyama S., Nakayama K., Ishida N., Kawakami K.,
Nakayama K.;
"Characterization of a mouse gene (Fbxw6) that encodes a homologue of
Caenorhabditis elegans SEL-10.";
Genomics 78:214-222(2001).
[6]
FUNCTION, SUBUNIT, AND IDENTIFICATION BY MASS SPECTROMETRY.
PubMed=12140560; DOI=10.1038/nature00890;
Yoshida Y., Chiba T., Tokunaga F., Kawasaki H., Iwai K., Suzuki T., Ito Y.,
Matsuoka K., Yoshida M., Tanaka K., Tai T.;
"E3 ubiquitin ligase that recognizes sugar chains.";
Nature 418:438-442(2002).
[7]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-131, AND IDENTIFICATION BY
MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
Spleen, and Testis;
PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
"A tissue-specific atlas of mouse protein phosphorylation and expression.";
Cell 143:1174-1189(2010).
[8]
INTERACTION WITH FBXO45.
PubMed=19996097; DOI=10.1074/jbc.m109.046284;
Tada H., Okano H.J., Takagi H., Shibata S., Yao I., Matsumoto M., Saiga T.,
Nakayama K.I., Kashima H., Takahashi T., Setou M., Okano H.;
"Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.";
J. Biol. Chem. 285:3840-3849(2010).
[9]
IDENTIFICATION IN AN SCF COMPLEX, AND INTERACTION WITH FBXW15.
PubMed=23319590; DOI=10.1074/jbc.m112.426882;
Zou C., Chen Y., Smith R.M., Snavely C., Li J., Coon T.A., Chen B.B.,
Zhao Y., Mallampalli R.K.;
"SCF(Fbxw15) mediates histone acetyltransferase binding to origin
recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate
cell proliferation.";
J. Biol. Chem. 288:6306-6316(2013).
[10]
DEGRADATION VIA AUTOPHAGY.
PubMed=29937374; DOI=10.1016/j.cmet.2018.05.023;
Toledo M., Batista-Gonzalez A., Merheb E., Aoun M.L., Tarabra E., Feng D.,
Sarparanta J., Merlo P., Botre F., Schwartz G.J., Pessin J.E., Singh R.;
"Autophagy regulates the liver clock and glucose metabolism by degrading
CRY1.";
Cell Metab. 28:268-281(2018).
-!- FUNCTION: Essential component of the SCF (SKP1-CUL1-F-box protein)
ubiquitin ligase complex, which mediates the ubiquitination of proteins
involved in cell cycle progression, signal transduction and
transcription. In the SCF complex, serves as an adapter that links the
F-box protein to CUL1. The functional specificity of the SCF complex
depends on the F-box protein as substrate recognition component.
SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and
participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of
phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB,
NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.
SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is
involved in regulation of G1/S transition. SCF(SKP2) directs
ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and
probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E,
NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs
ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and
DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) directs
ubiquitination of BCL6 and DTL but does not seem to direct
ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA
at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-
RELA dimer to translocate into the nucleus and to activate
transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3)
and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9)
directs ubiquitination of TTI1 and TELO2 (By similarity).
{ECO:0000250|UniProtKB:P63208, ECO:0000269|PubMed:10097128,
ECO:0000269|PubMed:12140560, ECO:0000269|PubMed:9990853}.
-!- PATHWAY: Protein modification; protein ubiquitination.
-!- SUBUNIT: Interacts with KDM2B, forming heterodimers (By similarity).
The KDM2B-SKP1 heterodimeric complex interacts with the PCGF1-BCORL
heterodimeric complex to form a homotetrameric polycomb repression
complex 1 (PRC1.1) (By similarity). Component of multiple SCF (SKP1-
CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1,
RBX1 and a variable F-box domain-containing protein as substrate-
specific subunit. Component of the SCF(FBXW11) complex containing
FBXW11. Component of the SCF(SKP2) complex containing SKP2, in which it
interacts directly with SKP1, SKP2 and RBX1. Component of the
SCF(FBXW2) complex containing FBXw2. Component of the SCF(FBXO32)
complex containing FBXO32. Component of the probable SCF(FBXO7) complex
containing FBXO7. Component of the SCF(FBXO10) complex containing
FBXO10. Component of the SCF(FBXO11) complex containing FBXO11.
Component of the SCF(FBXO25) complex containing FBXO25. Component of
the SCF(FBXO33) complex containing FBXO33. Component of the probable
SCF(FBXO4) complex containing FBXO4. Component of the SCF(FBXO44)
complex, composed of SKP1, CUL1 and FBXO44. Component of the SCF(BTRC)
complex, composed of SKP1, CUL1 and BTRC. This complex binds
phosphorylated NFKBIA. Part of a SCF complex consisting of CUL1, RBX1,
SKP1 and FBXO2. Component of a SCF(SKP2)-like complex containing CUL1,
SKP1, TRIM21 and SKP2. Component of the SCF(FBXO17) complex, composed
of SKP1, CUL1 and FBXO17. Component of the SCF(FBXO27) complex,
composed of SKP1, CUL1 and FBXO27. Component of the SCF(CCNF) complex
consisting of CUL1, RBX1, SKP1 and CCNF. Component of the SCF(FBXL3)
complex composed of CUL1, SKP1, RBX1 and FBXL3. Component of the
SCF(FBXL21) complex composed of CUL1, SKP1, RBX1 and FBXL21. Component
of the SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Component of
the SCF(FBXW7) composed of CUL1, SKP1, RBX1 and FBXW7. Component of the
SCF(FBXW15) complex containing FBXW15 (PubMed:23319590). Interacts with
CEP68 (By similarity). Interacts with FBXW15 (PubMed:23319590).
Interacts with NOTCH2 (By similarity). The SKP1-KDM2A and SKP1-KDM2B
complexes interact with UBB (By similarity).
{ECO:0000250|UniProtKB:P63208, ECO:0000269|PubMed:10097128,
ECO:0000269|PubMed:11735228, ECO:0000269|PubMed:12140560,
ECO:0000269|PubMed:19996097, ECO:0000269|PubMed:23319590,
ECO:0000269|PubMed:9990853}.
-!- INTERACTION:
Q9WTX5; Q9QXW2: Fbxw5; NbExp=2; IntAct=EBI-1202363, EBI-16031930;
Q9WTX5; P62137: Ppp1ca; NbExp=2; IntAct=EBI-1202363, EBI-357187;
Q9WTX5; Q9CQJ4: Rnf2; NbExp=4; IntAct=EBI-1202363, EBI-927321;
Q9WTX5; Q9UKT7: FBXL3; Xeno; NbExp=4; IntAct=EBI-1202363, EBI-2557269;
-!- PTM: Undergoes autophagy-mediated degradation in the liver in a time-
dependent manner. {ECO:0000269|PubMed:29937374}.
-!- SIMILARITY: Belongs to the SKP1 family. {ECO:0000305}.
---------------------------------------------------------------------------
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EMBL; AF083214; AAD16036.1; -; mRNA.
EMBL; AK002983; BAB22496.1; -; mRNA.
EMBL; AK010628; BAB27074.1; -; mRNA.
EMBL; AK012498; BAB28281.1; -; mRNA.
EMBL; AK014245; BAB29222.1; -; mRNA.
EMBL; AK027909; BAC25660.1; -; mRNA.
EMBL; AK078330; BAC37220.1; -; mRNA.
EMBL; AK088339; BAC40292.1; -; mRNA.
EMBL; BC002115; AAH02115.1; -; mRNA.
CCDS; CCDS24669.1; -.
RefSeq; NP_035673.3; NM_011543.4.
RefSeq; XP_006532849.1; XM_006532786.2.
SMR; Q9WTX5; -.
BioGRID; 203998; 103.
CORUM; Q9WTX5; -.
DIP; DIP-38596N; -.
IntAct; Q9WTX5; 57.
MINT; Q9WTX5; -.
STRING; 10090.ENSMUSP00000038744; -.
iPTMnet; Q9WTX5; -.
PhosphoSitePlus; Q9WTX5; -.
SwissPalm; Q9WTX5; -.
REPRODUCTION-2DPAGE; Q9WTX5; -.
EPD; Q9WTX5; -.
jPOST; Q9WTX5; -.
MaxQB; Q9WTX5; -.
PaxDb; Q9WTX5; -.
PRIDE; Q9WTX5; -.
ProteomicsDB; 261188; -.
Antibodypedia; 4566; 544 antibodies.
DNASU; 21402; -.
Ensembl; ENSMUST00000037324; ENSMUSP00000038744; ENSMUSG00000036309.
Ensembl; ENSMUST00000109072; ENSMUSP00000104700; ENSMUSG00000036309.
GeneID; 21402; -.
KEGG; mmu:21402; -.
UCSC; uc007ivf.2; mouse.
CTD; 6500; -.
MGI; MGI:103575; Skp1.
eggNOG; KOG1724; Eukaryota.
GeneTree; ENSGT00390000012652; -.
InParanoid; Q9WTX5; -.
OMA; PLKSADM; -.
OrthoDB; 1412723at2759; -.
PhylomeDB; Q9WTX5; -.
TreeFam; TF354233; -.
Reactome; R-MMU-1169091; Activation of NF-kappaB in B cells.
Reactome; R-MMU-1170546; Prolactin receptor signaling.
Reactome; R-MMU-187577; SCF(Skp2)-mediated degradation of p27/p21.
Reactome; R-MMU-195253; Degradation of beta-catenin by the destruction complex.
Reactome; R-MMU-202424; Downstream TCR signaling.
Reactome; R-MMU-2565942; Regulation of PLK1 Activity at G2/M Transition.
Reactome; R-MMU-2871837; FCERI mediated NF-kB activation.
Reactome; R-MMU-5607761; Dectin-1 mediated noncanonical NF-kB signaling.
Reactome; R-MMU-5607764; CLEC7A (Dectin-1) signaling.
Reactome; R-MMU-5610780; Degradation of GLI1 by the proteasome.
Reactome; R-MMU-5610785; GLI3 is processed to GLI3R by the proteasome.
Reactome; R-MMU-5676590; NIK-->noncanonical NF-kB signaling.
Reactome; R-MMU-5684264; MAP3K8 (TPL2)-dependent MAPK1/3 activation.
Reactome; R-MMU-68949; Orc1 removal from chromatin.
Reactome; R-MMU-69231; Cyclin D associated events in G1.
Reactome; R-MMU-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
Reactome; R-MMU-8939902; Regulation of RUNX2 expression and activity.
Reactome; R-MMU-8951664; Neddylation.
Reactome; R-MMU-9020702; Interleukin-1 signaling.
Reactome; R-MMU-917937; Iron uptake and transport.
Reactome; R-MMU-983168; Antigen processing: Ubiquitination & Proteasome degradation.
UniPathway; UPA00143; -.
BioGRID-ORCS; 21402; 17 hits in 51 CRISPR screens.
ChiTaRS; Skp1a; mouse.
PRO; PR:Q9WTX5; -.
Proteomes; UP000000589; Chromosome 11.
RNAct; Q9WTX5; protein.
Bgee; ENSMUSG00000036309; Expressed in cochlea and 320 other tissues.
ExpressionAtlas; Q9WTX5; baseline and differential.
Genevisible; Q9WTX5; MM.
GO; GO:0005813; C:centrosome; IDA:CACAO.
GO; GO:0031467; C:Cul7-RING ubiquitin ligase complex; IDA:UniProtKB.
GO; GO:0005737; C:cytoplasm; ISO:MGI.
GO; GO:0005829; C:cytosol; IDA:UniProtKB.
GO; GO:0005654; C:nucleoplasm; TAS:Reactome.
GO; GO:0005634; C:nucleus; ISO:MGI.
GO; GO:0031519; C:PcG protein complex; IEA:Ensembl.
GO; GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO; GO:0008013; F:beta-catenin binding; ISO:MGI.
GO; GO:0097602; F:cullin family protein binding; ISO:MGI.
GO; GO:1990444; F:F-box domain binding; ISO:MGI.
GO; GO:0019904; F:protein domain specific binding; ISO:MGI.
GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; ISO:MGI.
GO; GO:0035518; P:histone H2A monoubiquitination; ISO:MGI.
GO; GO:0051457; P:maintenance of protein location in nucleus; ISO:MGI.
GO; GO:1904668; P:positive regulation of ubiquitin protein ligase activity; ISO:MGI.
GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:MGI.
GO; GO:0000209; P:protein polyubiquitination; ISO:MGI.
GO; GO:0016567; P:protein ubiquitination; ISO:MGI.
GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:MGI.
Gene3D; 3.30.710.10; -; 1.
InterPro; IPR016897; SKP1.
InterPro; IPR001232; SKP1-like.
InterPro; IPR036296; SKP1-like_dim_sf.
InterPro; IPR011333; SKP1/BTB/POZ_sf.
InterPro; IPR016072; Skp1_comp_dimer.
InterPro; IPR016073; Skp1_comp_POZ.
Pfam; PF01466; Skp1; 1.
Pfam; PF03931; Skp1_POZ; 1.
PIRSF; PIRSF028729; E3_ubiquit_lig_SCF_Skp; 1.
SMART; SM00512; Skp1; 1.
SUPFAM; SSF54695; SSF54695; 1.
SUPFAM; SSF81382; SSF81382; 1.
1: Evidence at protein level;
Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation;
Ubl conjugation pathway.
CHAIN 1..163
/note="S-phase kinase-associated protein 1"
/id="PRO_0000187252"
REGION 63..83
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 104..163
/note="Interaction with the F-box domain of F-box proteins"
/evidence="ECO:0000250"
MOD_RES 131
/note="Phosphothreonine"
/evidence="ECO:0007744|PubMed:21183079"
CROSSLNK 142
/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
G-Cter in SUMO1)"
/evidence="ECO:0000250|UniProtKB:P63208"
CONFLICT 41
/note="D -> N (in Ref. 2; BAC37220)"
/evidence="ECO:0000305"
SEQUENCE 163 AA; 18672 MW; AE184C00BE6556DB CRC64;
MPTIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ
WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC
KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVRKENQWC EEK


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U1889h CLIA CDK2,Cell division protein kinase 2,Cyclin-dependent kinase 2,Homo sapiens,Human,p33 protein kinase 96T
E1889h ELISA kit CDK2,Cell division protein kinase 2,Cyclin-dependent kinase 2,Homo sapiens,Human,p33 protein kinase 96T
E1889h ELISA CDK2,Cell division protein kinase 2,Cyclin-dependent kinase 2,Homo sapiens,Human,p33 protein kinase 96T
EIAAB06559 CDI1,CDK2-associated dual-specificity phosphatase,CDKN3,CIP2,Cyclin-dependent kinase inhibitor 3,Cyclin-dependent kinase interactor 1,Cyclin-dependent kinase-interacting protein 2,Homo sapiens,Human,K
E0739m ELISA Cdk5,Cdkn5,Cell division protein kinase 5,CR6 protein kinase,CRK6,Crk6,Cyclin-dependent kinase 5,Mouse,Mus musculus,Serine_threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subuni 96T
U0739m CLIA Cdk5,Cdkn5,Cell division protein kinase 5,CR6 protein kinase,CRK6,Crk6,Cyclin-dependent kinase 5,Mouse,Mus musculus,Serine_threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit 96T
E0739b ELISA kit Bos taurus,Bovine,CDK5,CDKN5,Cell division protein kinase 5,Cyclin-dependent kinase 5,PDPK,Proline-directed protein kinase 33 kDa subunit,Serine_threonine-protein kinase PSSALRE,Tau protein 96T
E0739m ELISA kit Cdk5,Cdkn5,Cell division protein kinase 5,CR6 protein kinase,CRK6,Crk6,Cyclin-dependent kinase 5,Mouse,Mus musculus,Serine_threonine-protein kinase PSSALRE,Tau protein kinase II catalytic s 96T
U0739b CLIA Bos taurus,Bovine,CDK5,CDKN5,Cell division protein kinase 5,Cyclin-dependent kinase 5,PDPK,Proline-directed protein kinase 33 kDa subunit,Serine_threonine-protein kinase PSSALRE,Tau protein kinas 96T
E0739b ELISA Bos taurus,Bovine,CDK5,CDKN5,Cell division protein kinase 5,Cyclin-dependent kinase 5,PDPK,Proline-directed protein kinase 33 kDa subunit,Serine_threonine-protein kinase PSSALRE,Tau protein kina 96T
pka-356 Recombinant Human S-phase Kinase-Associated Protein 1 Isoform A PROTEIN KINASES 25
pka-356 Recombinant Human S-phase Kinase-Associated Protein 1 Isoform A PROTEIN KINASES 5
orb80869 Human S-phase Kinase-Associated Protein Isoform A protein Proteins 5
Pathways :
WP1493: Carbon assimilation C4 pathway
WP2032: TSH signaling pathway
WP1678: Nucleotide excision repair
WP2199: Seed Development
WP1689: Porphyrin and chlorophyll metabolism
WP1644: DNA replication
WP1892: Protein folding
WP813: G Protein Signaling Pathways
WP1654: gamma-Hexachlorocyclohexane degradation
WP1693: Purine metabolism
WP2292: Chemokine signaling pathway
WP1531: Vitamin D synthesis
WP1661: Glyoxylate and dicarboxylate metabolism
WP1672: Mismatch repair
WP35: G Protein Signaling Pathways
WP1714: Tyrosine metabolism
WP73: G Protein Signaling Pathways
WP1371: G Protein Signaling Pathways
WP1676: Non-homologous end-joining
WP1165: G Protein Signaling Pathways
WP1616: ABC transporters
WP2218: sGC
WP1625: Base excision repair
WP1888: Post-translational protein modification
WP1685: Peptidoglycan biosynthesis

Related Genes :
[SKP1 SKP1A QtrA-12126 QtsA-19170] S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
[SKP2 FBXL1] S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
[Skp2] S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/WD-40 protein 1) (FWD1)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[CDK2 CDKN2] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
[Cdk2 Cdkn2] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[Cdk2 Cdkn2] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[CDK2 CDKN2] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[CDK2 CDKN7] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[CDKN3 CDI1 CIP2 KAP] Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)
[Cdkn2a] Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p19ARF)
[cdk2 eg1] Cyclin-dependent kinase 2 (EC 2.7.11.22) (CDC2 homolog Eg1 protein kinase) (Cell division protein kinase 2)
[CDK2 CDKN2] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[cdk-2 K03E5.3] Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
[Cdkn2a] Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p19ARF)
[SCAPER KIAA1454 ZNF291 MSTP063] S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291)
[CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1] Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
[skp1 psh1 sph1 SPBC409.05] Suppressor of kinetochore protein 1 (P19/Skp1 homolog)
[Cdkn1a Cip1 Waf1] Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein) (p21)
[CDKN1A CIP1 WAF1] Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (p21)
[gag] Gag polyprotein (Pr53Gag) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-gag (NC-gag)]
[gag-pro-pol] Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-pro (NC') (NC-pro); Protease (PR) (EC 3.4.23.-); p1; Reverse transcriptase/ribonuclease H, p49 subunit (p49 RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Reverse transcriptase/ribonuclease H, p62 subunit (p62 RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[gag-pro prt] Gag-Pro polyprotein (Pr76Gag-Pro) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-pro (NC') (NC-pro); Protease (PR) (EC 3.4.23.-); p1; Transframe peptide (TFP) (p8)]
[S] Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
[stk-1 bur1 B20D17.070 NCU01435] Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC 2.7.11.23) (Serine-threonine kinase 1)
[cdk1-a cdc2-a cdc2x1.1] Cyclin-dependent kinase 1-A (CDK1-A) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog 1) (Cell division control protein 2-A) (Cell division protein kinase 1-A) (p34 protein kinase 1)
[Cdk1 Cdc2 Cdc2a Cdkn1] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
[DGK1 HSD1 YOR311C O6111] CTP-dependent diacylglycerol kinase 1 (EC 2.7.1.174) (Diglyceride kinase 1) (DAG kinase 1) (High-copy suppressor of SLY1 defect protein 1)
[nnr nnrD nnrE A3104_11915 A3S30_19665 A3T81_21675 A3U32_23435 A3V03_21575 A3V89_22115 A3W57_22140 A3X15_22160 A3X55_21685 A3Y76_14605 A4N07_22285 A4O05_13700 A4O41_05265 A4R48_22080 A9U69_22255 AAA76_20340 AAB27_18985 AAB79_03070 AAC35_06000 ADQ28_23005 AF497_21520 AGM99_01505 AHN93_01515 AKH62_11790 AL144_04480 AL168_02095 AL184_03665 AQ530_03515 AU613_19740 AVA38_18590 AVC05_01495 AVL16_22555 AWT30_09535 AXX99_06020 B1265_01505 B1398_16630 B1642_23230 B1P38_04920 B2E31_03355 B4V59_03840 B4W90_14915 B6362_05595 B7Q27_01505 B8Y16_05865 B8Z46_22290 B9C90_07460 B9C96_05405 B9M14_07545 B9O84_03660 BBQ66_05585 BIC00_08330 BIC13_14510 BK110_09575 BKM50_11315 BMS46_01505 BMU56_09035 BZ203_06955 BZZ88_08070 C5W43_08230 CA117_06625 CB102_00985 CB119_00985 CB198_09030 CB380_07720 CB535_06910 CB570_00990 CB646_05015 CBM67_21760 CBM76_21380 CBZ90_21695 CC339_04035 CC403_03335 CC453_02040 CC652_09145 CC971_07405 CCP17_01500 CDZ72_03200 CE70_13525 CED07_02655 CEQ70_07505 CFF58_07550 CFF59_07100 CHN22_19910 CIX60_07020 CPS79_03750 CQO33_04955 CSG22_03545 CVR97_09130 D4361_14445 D4387_09005 D4422_03410 D5823_20700 D5N86_01575 D5N95_09780 D5O82_05670 D5P17_06815 D5X47_11065 D5Y28_07745 D6422_22155 D6J79_11255 D8S24_10700 DD95_00965 DLB93_10975 DLR28_11595 DMI89_05845 DMO92_10880 DN165_10610 DNB97_07755 DNM27_05145 DNZ37_05180 DO533_23225 DP680_10960 DPB42_02650 DPD91_03510 DPF41_01580 DPF68_05705 DPS76_03370 DQD22_12500 DQR44_06210 DRM14_08770 DRR75_10500 DRT38_04095 DRT61_07200 DRV05_05125 DSF94_09655 DSG41_17540 DTF68_08880 DU071_23815 DU223_08415 DU657_03970 DU879_06050 DUV75_11535 DWU22_16565 DY580_23265 DYM27_14705 E0935_23310 E1A11_11805 E6W45_09715 EBD14_10340 EBK21_08710 EC404_02370 EEQ30_18160 EER35_22295 EHB09_20270 EL822_04855 ELS01_25275 EPB30_12745 EQG93_06630 EVY71_20440 EW905_04205 F0D96_20705 F2P00_23020 F3Q97_10065 F3R12_05435 F9G02_04855 F9O44_00990 FEM52_07875 FGZ46_01505 FJM64_10520 FQC24_12860 FQX78_09970 G0038_10260 G0040_04475 G0042_07685 G0045_12485 G0047_13855 G0048_12905 G0051_11450 G0052_23590 G0059_11030 G0061_11920 G0062_12500 G0063_16275 G0067_13985 G0069_12775 G0070_08950 G0071_12535 G0072_10310 G0074_12900 G0076_15880 G0077_12835 G0080_14965 G0084_15965 G0086_13840 G0087_12905 G0088_11920 G0089_06320 G0090_22420 G0094_13250 G0100_12665 G0101_09385 G0102_12000 G0111_21240 G0113_13510 G0117_14430 G0123_12905 G0124_09920 G0148_23065 G0157_12325 G0170_23555 G0A05_04765 G0A32_05580 G0A39_06255 G0A43_05040 G0A44_08470 G0A46_12965 G0A50_23545 G0A51_09275 G0A52_05740 G0A53_07565 G0A56_07500 G0A58_07465 G0A60_17995 G0A61_07660 G0A63_04815 G0A66_08960 G0A67_07200 G0A68_05690 G0A70_08885 G0A73_09480 G0A76_08590 G0A79_21840 G0A92_10225 G0A96_08865 G0A97_09115 G0B03_12655 G0B05_09390 G0B07_10975 G0B08_22950 G0B12_10720 G0B96_04785 G0C03_12575 G0C04_15660 G0C34_07535 G0E15_19110 G0E20_06140 G0G84_16105 G0J24_13730 G0J26_12305 G0J27_07115 G0J28_11980 G0J31_06745 G0J33_11145 G0J34_13415 G0J36_08765 G0J37_20200 G0J40_10310 G0J43_01545 G0J44_20410 G0J45_08730 G0J46_15460 G0J47_19830 G0J49_09500 G0J50_01555 G0J51_10340 G0J53_08850 G0J55_19430 G0J58_22670 G0J59_05635 G0J62_17815 G0J65_08725 G0J66_21925 G0J67_22665 G0J69_22465 G0J71_22025 G0J73_03995 G0J76_22400 G0J79_23305 G0J81_19270 G0J82_03865 G0J85_22590 G0J89_01555 G0J92_05645 G0J94_04410 G0J96_06855 G0J97_18065 G0K00_04765 G0K02_10715 G0K03_10995 G0K04_02780 G0K05_22985 G0K07_22440 G0K10_01565 G0K13_11525 G0K15_08960 G0K16_08385 G0K18_04715 G0K19_01430 G0K20_20560 G0K23_09085 G0K25_22280 G0K26_23210 G0K28_09270 G0K30_24080 G0K31_21360 G0K32_21370 G0K33_22125 G0K37_22810 G0K38_06715 G0K39_19020 G0K41_13810 G0K42_10880 G0K44_22730 G0K46_22315 G0K47_08680 G0K48_01555 G0K49_05675 G0K52_04405 G0K53_04950 G0K56_04645 G0K58_19550 G0K59_01555 G0K61_05520 G0K65_10910 G0K68_01545 G0K70_23295 G0K72_19895 G0K74_23665 G0K75_23255 G0K78_05095 G0K80_01550 G0K83_07510 G0K84_09810 G0K85_01555 G0K88_000683 G0K89_000568 G0K90_000508 G0K95_003755 G0L00_001859 G0L02_000638 G0L03_05870 G0L06_06150 G0L07_08375 G0L10_19990 G0L14_06770 G0L15_02230 G0L18_05635 G0L19_08200 G0L20_14575 G0L24_07325 G0L25_04935 G0L29_02685 G0L31_03775 G0L32_04710 G0L34_14860 G0L35_12865 G0L36_13035 G0L37_07105 G0L38_11275 G0L40_12750 G0L42_10750 G0L48_09545 G0L49_06730 G0L51_08560 G0L52_09595 G0L55_08545 G0L59_07010 G0L62_08790 G0L63_08395 G0L65_11350 G0L67_07070 G0L68_21135 G0L70_01495 G0L73_21325 G0L76_10450 G0L77_03505 G0L78_05795 G0L79_07425 G0L83_10615 G0L86_001595 G0L88_06510 G0L89_08150 G0L91_03255 G0L93_04345 G0L96_08625 G0L98_04340 G0M00_03415 G0M02_06865 G0M05_13160 G0M06_001385 G0M13_001162 G0M14_16700 G0M16_07260 G0M18_003813 G0M21_02335 G0M22_001379 G0M25_001199 G0M26_21090 G0M29_001394 G0M30_19890 G0M33_23770 G0M35_21125 G0M36_15025 G0M38_15125 G0M39_17915 G0M41_17560 G0M45_03860 G0M46_001382 G0M48_003206 G0M53_18855 G0M55_07255 G0M56_08145 G0M58_08160 G0M63_07175 G0M65_06665 G0M67_08355 G0N45_22995 G0N48_14040 G0N51_03825 G0N53_22980 G0N55_11400 G0N57_00010 G0N58_23005 G0N59_23010 G0N60_23095 G0N61_09375 G0N62_22990 G0N64_11025 G0N65_22930 G0N66_23085 G0N67_23065 G0N71_04780 G0N75_16110 G0N78_21895 G0N82_10545 G0N84_15350 G0N85_24040 G0N86_23095 G0N88_10630 G0N89_10800 G0N90_22705 G0N92_17760 G0N94_20330 G0N95_23625 G0N98_20980 G0N99_05765 G0O00_05695 G0O10_23100 G0O14_22860 G0O15_07010 G0O18_13745 G0O19_12975 G0O20_05410 G0O22_22985 G0O25_22615 G0O27_09925 G0O31_10850 G0O32_22285 G0O36_10155 G0O37_07040 G0O39_16130 G0O40_13640 G0O41_10340 G0O42_04595 G0O43_15605 G0O44_11700 G0O47_09535 G0O52_22165 G0O55_11440 G0O57_04595 G0O58_14540 G0O59_06805 G0O60_22680 G0O63_06090 G0O66_07220 G0O68_10375 G0O70_11530 G0O71_09735 G0O74_04410 G0O75_09695 G0O77_22825 G0O78_09545 G0O80_11320 G0O81_07145 G0O82_16905 G0O84_11320 G0O85_15450 G0O86_04490 G0O87_13110 G0O88_07290 G0O89_16570 G0O92_14075 G0O93_16785 G0O94_04825 G0O97_23030 G0O99_03030 G0P00_05830 G0P01_06470 G0P02_09955 G0P05_04495 G0P06_22950 G0P08_07305 G0P12_03840 G0P13_16225 G0P17_10905 G0P18_15755 G0P19_12705 G0P24_08485 G0P26_09735 G0P28_11835 G0P30_09670 G0P31_13405 G0P36_11580 G0P37_07140 G0P41_06990 G0P44_09010 G0P45_10700 G0P48_10900 G0P49_04240 G0P52_08565 G0P53_13455 G0P56_10915 G0P57_09940 G0P58_22400 G0P63_18010 G0P65_10045 G0P67_06260 G0P68_03795 G0P69_22335 G0P73_18280 G0P75_23960 G0P76_04350 G1N61_10720 G1N64_12415 G1N66_12405 G1N68_12100 G1N71_13250 G1N72_12410 G1N86_13550 G1N87_12430 G1N91_14270 G1O00_12660 G1O02_13555 G1O04_12420 G1O05_12405 G1O08_13535 G1O10_12410 G1O12_13560 G1O16_13555 G1O17_12180 G1O18_13555 G1O20_13550 G1O23_12420 G1O25_13545 G1O26_13550 G1O27_12485 G1O28_13315 G1O29_12480 G1O32_13540 G1O34_13620 G1O38_13960 G1O40_13560 G1O43_13545 G1O46_12060 G1O48_13325 G1O49_12535 G1O51_13550 G1O53_13615 G1O62_13555 G1O63_13540 G1O65_13325 G1O67_12870 G1O68_11720 G1O69_13110 G1O71_13105 G1O72_11855 G1O76_13635 G1O77_13550 G1O80_13640 G1O81_12410 G1O83_12005 G1O84_13630 G1O87_13635 G1O88_13625 G1O89_13560 G1O90_13630 G1O93_13625 G1O94_13620 G1O96_13625 G1P02_13620 G1P03_13280 G1P06_13300 G1P09_12575 G1P10_13575 G1P12_13625 G1P14_10175 G1P15_13970 G1P17_13640 G1P19_13625 G1P23_13630 G1P24_13545 G1P25_11855 G1P26_13545 G1P29_13260 G1P31_13615 G1P35_13550 G1P36_13545 G1P37_13205 G1P40_12430 G1P44_13550 G1P45_13630 G1P47_12485 G1P48_13630 G1P51_13630 G1P52_13205 G1P53_13205 G1P54_13640 G1P55_13320 G1P56_13610 G1P57_10720 G1P58_13620 G1P59_13635 G1P61_23980 G1P64_13325 G1P67_13625 G1P69_13540 G1P72_12515 G1P75_13570 G1P76_13215 G1P78_12495 G1P83_12225 G1P84_13555 G1P87_13625 G1P90_13360 G1P91_13620 G1Q03_13235 G1Q08_12720 G1Q67_13630 G1Q78_09875 G1Q81_11340 G1Q83_12495 G1Q84_08650 G1Q85_11365 G1Q86_11715 G1Q88_11725 G1Q90_12170 G1Q91_12420 G1Q93_09170 G1Q96_12385 G1Q98_11910 G1Q99_22335 G1R01_13545 G1R02_12655 G1R03_13625 G1R04_13570 G1R08_09245 G1R13_11975 G1R15_09440 G1R20_14345 G1R21_11475 G1R22_11285 G1R23_08760 G1R27_12005 G1R28_13075 G1R29_13635 G1R30_13320 G1R31_12250 G1R36_13635 G1R38_18180 G1R40_12255 G1R42_13550 G1R44_13315 G1R45_09940 G1R47_12850 G1R48_06440 G1R51_12400 G1R53_13630 G1R63_13630 G1R69_09725 G1R87_11980 G1R93_13230 G1S02_12495 G2203_22150 G2212_02390 G2218_05480 G2279_10500 G2290_05710 G2793_13060 G2918_01515 G2951_22815 G3221_001120 G3230_002225 G3231_004971 G3247_000621 G3248_004290 G3254_000657 G3263_001003 G3270_000223 G3275_001976 G3312_001342 G3336_003846 G3357_000830 G3369_001554 G3433_000423 G3460_002051 G3464_000047 G3593_001051 G3A35_04535 G3V06_004409 G3V14_001761 G3V17_001609 G3V21_004148 G3V56_001941 G3V57_003126 G3X03_004298 G4189_001618 G4190_004249 G4192_004192 G4198_004562 G4201_003798 G4202_000501 G4A01_003580 G4A73_001420 G4A83_004704 G4A85_001081 G4A87_001998 G4B68_002875 G4B72_004591 G4B74_004402 G4C74_001467 G4D32_001167 G4D46_001331 G4F88_03160 G4F89_21210 G4F91_20865 G4F92_03160 G4G47_000304 G4G62_000179 G4G67_004715 G4G68_000780 G4G75_001230 G4G76_001971 G4G79_000501 G4G97_000963 G4H00_001841 G4H04_001859 G4H07_000277 G4H08_000970 G4H18_001970 G4H21_002013 G4H24_001959 G4H63_001799 G4I66_002109 G4J07_003114 G4J08_001003 G4J11_003314 G4J12_003592 G4J18_002204 G4J20_000694 G4J37_001805 G4J39_003834 G4J41_001252 G4J45_004787 G4J90_001032 G4K02_004567 G4K03_004658 G4O54_001852 G4O56_000652 G4O59_004375 G4O60_004588 G4O67_004614 G4O69_001138 G4P29_002660 G4P83_002002 G4P85_001270 G4P89_000745 G4P91_004289 G4P93_000925 G4Q12_001216 G4Q28_001959 G4Q31_001958 G4Q50_001423 G4Q52_001423 G4Q59_000925 G4Q60_001509 G4Q63_001410 G4Q67_000417 G4Q94_000976 G4R01_002882 G4R02_000925 G4R15_001414 G4R16_001699 G4W68_001327 G4W73_003000 G4W86_001855 G4W87_002248 G4W88_003688 G4W91_000984 G4Y10_001706 G9269_001321 G9302_002068 G9304_000623 G9305_000797 G9309_000779 G9313_001438 G9314_004671 G9367_002779 G9381_001217 G9C24_000440 G9C41_004428 G9C46_004336 G9C47_004352 G9C49_004415 G9C57_002249 G9C64_001580 G9G03_000673 G9G04_001975 G9G34_002649 G9G36_001047 G9G45_002358 G9G50_004591 G9G62_003596 G9W19_000375 G9W28_000842 G9W45_004104 G9W52_000348 G9W63_004309 G9W65_001966 G9W79_001611 G9W95_001967 G9W96_001102 G9X40_004481 GB021_08410 GB040_02730 GB055_01495 GB076_03915 GB106_04175 GB114_03815 GB120_06665 GB122_01510 GB131_04255 GB139_07780 GB171_05240 GB209_06680 GB221_02485 GB224_18770 GB238_04475 GB280_15095 GB321_14890 GB331_05905 GB339_01505 GB342_22590 GB368_02475 GB372_02445 GB416_20360 GB452_19400 GB459_04825 GB466_07010 GB505_01510 GB510_08155 GB551_22950 GB567_07675 GB645_04690 GBS44_18590 GBS58_08845 GBV53_08360 GBV54_07315 GBV60_03815 GBW03_05075 GBW44_01505 GBW52_23040 GBW76_04840 GBX12_03395 GBX20_03490 GBX46_04595 GBX55_05300 GBX64_06335 GBY13_09745 GBY23_03830 GBY73_10270 GBZ51_12095 GBZ55_06105 GCZ80_05780 GEZ01_12305 GJE27_23785 GJE28_09790 GNA88_000904 GNA97_000970 GNA99_000904 GNB28_004056 GNB36_002380 GNB86_002038 GNC11_002712 GNC19_000953 GNC45_001979 GNC75_001243 GNC95_002115 GND07_000714 GT380_09345 GTH60_13735 GTH62_10815 GTH63_22565 GTH66_18970 GTH67_23365 GTH68_14080 GTH70_07920 GTH72_05435 GTH73_08455 GTH75_09290 GTH78_07295 GTH79_20650 GTH81_19855 GTH85_10175 GTH87_13350 GTH89_08935 GTH90_17910 GTH91_11235 GTH93_14555 GTH94_11265 GTH99_14850 GXC51_01500 GXC56_01500 GXG40_01500 GYI58_05740 GYI62_001805 GYI77_07850 GYJ04_14695 GYJ24_08660 GYJ27_23070 GYJ28_003286 GYJ30_22330 GYJ32_15480 GYJ53_13635 GYJ59_07255 GYJ60_13615 H8S97_22220 KP44_01505 NG06_15025 R035_14735 Z700_13005 ZV33_21500 ZX03_19885 ZY40_08180] Bifunctional NAD(P)H-hydrate repair enzyme (Nicotinamide nucleotide repair protein) [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6)]
[gag-pol] Gag-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; Capsid protein p27, alternate cleaved 1; Capsid protein p27, alternate cleaved 2; Spacer peptide (SP) (p3); Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (pp32); p4]

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