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SEC24 homolog B, COPII coat complex component

 F6YGU5_HORSE            Unreviewed;      1176 AA.
F6YGU5;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
13-FEB-2019, entry version 45.
SubName: Full=SEC24 homolog B, COPII coat complex component {ECO:0000313|Ensembl:ENSECAP00000014374};
Name=SEC24B {ECO:0000313|VGNC:VGNC:22793};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000014374, ECO:0000313|Proteomes:UP000002281};
[1] {ECO:0000313|Ensembl:ENSECAP00000014374, ECO:0000313|Proteomes:UP000002281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014374,
ECO:0000313|Proteomes:UP000002281};
PubMed=19892987; DOI=10.1126/science.1178158;
Broad Institute Genome Sequencing Platform;
Broad Institute Whole Genome Assembly Team;
Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H.,
Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N.,
Penedo M.C.T., Raison J.M., Sharpe T., Vogel J., Andersson L.,
Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J.,
Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J.,
Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R.,
Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F.,
Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L.,
Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M.,
White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
"Genome sequence, comparative analysis, and population genetics of the
domestic horse.";
Science 326:865-867(2009).
[2] {ECO:0000313|Ensembl:ENSECAP00000014374}
IDENTIFICATION.
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014374};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
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STRING; 9796.ENSECAP00000014374; -.
PaxDb; F6YGU5; -.
Ensembl; ENSECAT00000017682; ENSECAP00000014374; ENSECAG00000016518.
VGNC; VGNC:22793; SEC24B.
eggNOG; KOG1985; Eukaryota.
eggNOG; COG5028; LUCA.
GeneTree; ENSGT00940000153603; -.
InParanoid; F6YGU5; -.
OMA; PAMYSAN; -.
TreeFam; TF354244; -.
Proteomes; UP000002281; Chromosome 2.
Bgee; ENSECAG00000016518; Expressed in 3 organ(s), highest expression level in adult mammalian kidney.
GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
Gene3D; 3.40.20.10; -; 1.
Gene3D; 3.40.50.410; -; 1.
InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
InterPro; IPR007123; Gelsolin-like_dom.
InterPro; IPR036180; Gelsolin-like_dom_sf.
InterPro; IPR006900; Sec23/24_helical_dom.
InterPro; IPR036175; Sec23/24_helical_dom_sf.
InterPro; IPR006896; Sec23/24_trunk_dom.
InterPro; IPR012990; Sec23_24_beta_S.
InterPro; IPR036465; vWFA_dom_sf.
InterPro; IPR006895; Znf_Sec23_Sec24.
InterPro; IPR036174; Znf_Sec23_Sec24_sf.
Pfam; PF00626; Gelsolin; 1.
Pfam; PF08033; Sec23_BS; 1.
Pfam; PF04815; Sec23_helical; 1.
Pfam; PF04811; Sec23_trunk; 1.
Pfam; PF04810; zf-Sec23_Sec24; 1.
SUPFAM; SSF53300; SSF53300; 1.
SUPFAM; SSF81811; SSF81811; 1.
SUPFAM; SSF82754; SSF82754; 1.
SUPFAM; SSF82919; SSF82919; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002281};
Protein transport {ECO:0000256|SAAS:SAAS00454053};
Reference proteome {ECO:0000313|Proteomes:UP000002281};
Transport {ECO:0000256|SAAS:SAAS00454053}.
DOMAIN 510 546 zf-Sec23_Sec24.
{ECO:0000259|Pfam:PF04810}.
DOMAIN 583 822 Sec23_trunk. {ECO:0000259|Pfam:PF04811}.
DOMAIN 827 911 Sec23_BS. {ECO:0000259|Pfam:PF08033}.
DOMAIN 922 1022 Sec23_helical.
{ECO:0000259|Pfam:PF04815}.
DOMAIN 1049 1121 Gelsolin-like.
{ECO:0000259|Pfam:PF00626}.
SEQUENCE 1176 AA; 127518 MW; 5D6AA3D54C893050 CRC64;
GPAQNQMQFP SGYGLHPQNY IAPSGHYAQG PGKMTSLPLD SQHGDYYSGL YTVPTQNVVT
PNTAGQQPGA QQMYGRVLPA PHMAGSALGS FPGATSSASH VHTSASVNHH NSPAVGAANS
SVASQGFPST CGHYAMSTVS NAAYPRVSYS SPPAGDPYGQ QMFTSQNAPP VRPIRDNSFS
GQNTAISHPS PLPPPPPQQY HQEQSLSGYS TLSWSASGLP STQDNLLRNH TGSLATANNN
PTSPVADSLS SSVMQNVQPP VSSPVVSTVL SGASSARTPA AACHPAEPAA SVTQPSELFQ
QKGVDSSSTT SSASPGPNSY DALEGGSYPD MLSSSASSPA PDPAPESDPT SAPAPAAAQP
SKVAKPFGYG YPALQPGYQN AAAPPGAGPP SASPVYSGFQ QYAQQYPGLN QLSSGLGGLS
LQSAPQPESL RPVNLTQDRN VLPVTPVWAP VPNLNLDLRK LNCSPDSFRC TLTSIPQTQA
LLNKAKLPLG LLLHPFRDLT QLPVITSNTI VRCRSCRTYI NPFVSFIDQR RWKCNLCYRV
NDVPEEFMYN PLTRSYGEPH KRPEVQNSTV EFIASSDYML RPPQPAVYLF VLDVSHNAVE
AGYLTILCQS LLENLDKLPG DSRTRIGFLT FDSTIHFYDL QEGLSQPQML IVSEIDDVFL
PTPDSLLVNL HESKELIKDL LNALPTMFTN TRETHSALGP ALQAAFKLMS PTGGRVSVFQ
TQLPSLGAGL LQSREDPNQR SSTKVVQHLG PATDFYKKLA LDCSGQQTAV DLFLLSSQYS
DLASLACMSK YSAGCIYYYP SFHCTHNPSQ AEKLQKDLRR YLTRKIGFEA VMRIRCTKGL
SMHTFHGNFF VRSTDLLSLA NINPDAGFAV QLSIEESLTD TSLVCFQTAL LYTSSKGERR
IRVHTLCLPV VSSLADVYAG VDVQAAICLL ANMAVDRSVS SSLSDARDAL VNAVVDSLSA
YGSTISNLQH SALIAPSSLK LFPLYVLALL KQKAFRTGTS TRLDDRVYAM CQIKCQPLVH
LMKMIHPNLY RIDRLTDEGA IHVNDRVVPQ PPLQKLSAEK LTREGAFLMD CGSVFYIWIG
KSCDNNFIED VLGCPNFASI PQKMTHLPEL DTLSSERARS FITWLRDNRP LSPVLHVVKD
ESPAKTEFFQ HLIEDRTEAA FSYYEFLLHI QQHICK


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Kits Elisa; taq POLYMERASE

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Pathways :
WP1122: Blood Clotting Cascade
WP1224: EBV LMP1 signaling
WP1571: EBV LMP1 signaling
WP1624: Bacterial secretion system
WP1713: Two-component system
WP2340: Thiamine (vitamin B1) biosynthesis and salvage
WP2341: vitamin B1 (thiamin) biosynthesis and salvage pathway
WP255: Blood Clotting Cascade
WP262: EBV LMP1 signaling
WP272: Blood Clotting Cascade
WP32: Translation Factors
WP460: Blood Clotting Cascade
WP775: Blood Clotting Cascade
WP887: Blood Clotting Cascade
WP1001: Peptide GPCRs
WP1003: Ovarian Infertility Genes
WP1006: metapathway biotransformation
WP1008: amino acid conjugation of benzoic acid
WP1009: MAPK Cascade
WP101: Synthesis and Degradation of Ketone Bodies
WP1011: T Cell Receptor Signaling Pathway
WP1012: IL-7 Signaling Pathway
WP1015: Synthesis and Degradation of Ketone Bodies
WP1018: Apoptosis
WP1019: FAS pathway and Stress induction of HSP regulation

Related Genes :
[SEC24 ANU1 YIL109C] Protein transport protein SEC24 (Abnormal nuclear morphology 1)
[SEC24B] Protein transport protein Sec24B (SEC24-related protein B)
[SEC24C KIAA0079] Protein transport protein Sec24C (SEC24-related protein C)
[SEC24D KIAA0755] Protein transport protein Sec24D (SEC24-related protein D)
[SEC24A] Protein transport protein Sec24A (SEC24-related protein A)
[Sec24CD BcDNA:LP05220 Dmel\CG10882 FBgn0031408 gho Sec24 sec24 sfb3 Sten sten CG10882 Dmel_CG10882] LP05220p (Secretory 24CD, isoform A) (Secretory 24CD, isoform B)
[Sec24CD BcDNA:LP05220 Dmel\CG10882 FBgn0031408 gho Sec24 sec24 sfb3 Sten sten CG10882 Dmel_CG10882] Secretory 24CD, isoform C
[Sec24a] Protein transport protein Sec24A (SEC24-related protein A)
[Sec24b] Sec24-related gene family, member B (S. cerevisiae)
[Sec24b] Sec24-related gene family, member B (S. cerevisiae) (Fragment)
[Sec24b] Sec24b protein
[SFB3 LST1 YHR098C] SED5-binding protein 3 (Lethal with SEC13 protein 1) (SEC24-related protein 3)
[Sec24b] Sec24-related gene family, member B (S. cerevisiae) (Fragment)
[SFB2 ISS1 YNL049C N2505 YNL2505C] SED5-binding protein 2 (SEC24-related protein 2)
[SEC24A] Protein transport protein Sec24A (SEC24-related protein A)
[SEC24 CNBB5410] Protein transport protein SEC24
[Sec24b] Uncharacterized protein (Fragment)
[Sec24b] Uncharacterized protein (Fragment)
[sec24 SPAC22F8.08] Protein transport protein sec24
[At3g07100 T1B9.25] Protein transport protein Sec24-like At3g07100
[SEC24 CNB00260] Protein transport protein SEC24
[Sec24b Sec24b_predicted rCG_28935] SEC24 homolog B, COPII coat complex component (SEC24 related gene family, member B (S. cerevisiae) (Predicted))
[Sec24b] Uncharacterized protein (Fragment)
[SEC24 UMAG_03209] Protein transport protein SEC24
[SAR1 YPL218W] Small COPII coat GTPase SAR1 (EC 3.6.5.-) (GTP-binding protein SAR1) (Secretion-associated RAS-related protein 1)
[SEC24 CIMG_01714] Protein transport protein SEC24
[SEC22B SEC22L1] Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
[CEF At3g44340 T22K7_20] Protein transport protein Sec24-like CEF
[SEC23B] Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
[SEC23 YPR181C P9705.14] Protein transport protein SEC23

Bibliography :