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Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g)

 SIRPG_HUMAN             Reviewed;         387 AA.
Q9P1W8; B1AKP6; Q5D051; Q5JV25; Q5MKL4; Q8WWA5; Q9NQK8;
28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 3.
07-APR-2021, entry version 166.
RecName: Full=Signal-regulatory protein gamma;
Short=SIRP-gamma;
AltName: Full=CD172 antigen-like family member B;
AltName: Full=Signal-regulatory protein beta-2;
Short=SIRP-b2;
Short=SIRP-beta-2;
AltName: CD_antigen=CD172g;
Flags: Precursor;
Name=SIRPG; Synonyms=SIRPB2;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, AND VARIANTS
ALA-263 AND LEU-286.
TISSUE=Placenta;
PubMed=11185750; DOI=10.1007/s100380070013;
Ichigotani Y., Matsuda S., Machida K., Oshima K., Iwamoto T., Yamaki K.,
Hayakawa T., Hamaguchi M.;
"Molecular cloning of a novel human gene (SIRP-B2) which encodes a new
member of the SIRP/SHPS-1 protein family.";
J. Hum. Genet. 45:378-382(2000).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, INTERACTION WITH CD47,
SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
TISSUE=T-cell;
PubMed=15383453; DOI=10.1182/blood-2004-07-2823;
Piccio L., Vermi W., Boles K.S., Fuchs A., Strader C.A., Facchetti F.,
Cella M., Colonna M.;
"Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-
CD47 interaction costimulates T-cell proliferation.";
Blood 105:2421-2427(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=11780052; DOI=10.1038/414865a;
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
"The DNA sequence and comparative analysis of human chromosome 20.";
Nature 414:865-871(2001).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
Hunkapiller M.W., Myers E.W., Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
TISSUE=Lung, and Ovary;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project:
the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[6]
GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-243.
TISSUE=Leukemic T-cell;
PubMed=19349973; DOI=10.1038/nbt.1532;
Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,
Schiess R., Aebersold R., Watts J.D.;
"Mass-spectrometric identification and relative quantification of N-linked
cell surface glycoproteins.";
Nat. Biotechnol. 27:378-386(2009).
[7]
X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 29-147, AND DISULFIDE BOND.
PubMed=18657508; DOI=10.1016/j.molcel.2008.05.026;
Hatherley D., Graham S.C., Turner J., Harlos K., Stuart D.I., Barclay A.N.;
"Paired receptor specificity explained by structures of signal regulatory
proteins alone and complexed with CD47.";
Mol. Cell 31:266-277(2008).
-!- FUNCTION: Probable immunoglobulin-like cell surface receptor. On
binding with CD47, mediates cell-cell adhesion. Engagement on T-cells
by CD47 on antigen-presenting cells results in enhanced antigen-
specific T-cell proliferation and costimulates T-cell activation.
{ECO:0000269|PubMed:15383453}.
-!- SUBUNIT: Interacts with CD47. {ECO:0000269|PubMed:15383453}.
-!- INTERACTION:
Q9P1W8; Q08722: CD47; NbExp=2; IntAct=EBI-1268284, EBI-1268321;
Q9P1W8; P01100: FOS; NbExp=3; IntAct=EBI-1268284, EBI-852851;
Q9P1W8; P50440: GATM; NbExp=3; IntAct=EBI-1268284, EBI-2552594;
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:15383453}; Single-
pass type I membrane protein {ECO:0000269|PubMed:15383453}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=4;
Name=1;
IsoId=Q9P1W8-1; Sequence=Displayed;
Name=2;
IsoId=Q9P1W8-2; Sequence=VSP_007027;
Name=3;
IsoId=Q9P1W8-3; Sequence=VSP_007028;
Name=4;
IsoId=Q9P1W8-4; Sequence=VSP_026960;
-!- TISSUE SPECIFICITY: Detected in liver, and at very low levels in brain,
heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed
on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells,
CD20+ cells, and all activated NK cells. Mainly present in the
paracortical T-cell area of lymph nodes, with only sparse positive
cells in the mantle and in the germinal center of B-cell follicles. In
the thymus, primarily expressed in the medulla on mature T-lymphocytes
that have undergone thymic selection. {ECO:0000269|PubMed:11185750,
ECO:0000269|PubMed:15383453}.
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EMBL; AB042624; BAA95692.1; -; mRNA.
EMBL; AY748247; AAV88530.1; -; mRNA.
EMBL; AY748248; AAV88531.1; -; mRNA.
EMBL; AL109809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AL138804; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471133; EAX10616.1; -; Genomic_DNA.
EMBL; BC020629; AAH20629.2; -; mRNA.
EMBL; BC064532; AAH64532.1; -; mRNA.
CCDS; CCDS13020.2; -. [Q9P1W8-1]
CCDS; CCDS13021.2; -. [Q9P1W8-3]
CCDS; CCDS33434.1; -. [Q9P1W8-4]
RefSeq; NP_001034597.1; NM_001039508.1. [Q9P1W8-4]
RefSeq; NP_061026.2; NM_018556.3. [Q9P1W8-1]
RefSeq; NP_543006.2; NM_080816.2. [Q9P1W8-3]
RefSeq; XP_011527588.1; XM_011529286.2. [Q9P1W8-2]
PDB; 2JJW; X-ray; 1.70 A; A=29-147.
PDB; 4I2X; X-ray; 2.48 A; E/F=29-347.
PDBsum; 2JJW; -.
PDBsum; 4I2X; -.
SMR; Q9P1W8; -.
BioGRID; 120664; 3.
IntAct; Q9P1W8; 5.
STRING; 9606.ENSP00000305529; -.
GlyGen; Q9P1W8; 4 sites.
iPTMnet; Q9P1W8; -.
PhosphoSitePlus; Q9P1W8; -.
BioMuta; SIRPG; -.
DMDM; 124053651; -.
EPD; Q9P1W8; -.
jPOST; Q9P1W8; -.
MassIVE; Q9P1W8; -.
MaxQB; Q9P1W8; -.
PaxDb; Q9P1W8; -.
PeptideAtlas; Q9P1W8; -.
PRIDE; Q9P1W8; -.
ProteomicsDB; 83672; -. [Q9P1W8-1]
ProteomicsDB; 83673; -. [Q9P1W8-2]
ProteomicsDB; 83674; -. [Q9P1W8-3]
ProteomicsDB; 83675; -. [Q9P1W8-4]
ABCD; Q9P1W8; 2 sequenced antibodies.
Antibodypedia; 6584; 326 antibodies.
DNASU; 55423; -.
Ensembl; ENST00000216927; ENSP00000216927; ENSG00000089012. [Q9P1W8-4]
Ensembl; ENST00000303415; ENSP00000305529; ENSG00000089012. [Q9P1W8-1]
Ensembl; ENST00000344103; ENSP00000342759; ENSG00000089012. [Q9P1W8-3]
Ensembl; ENST00000381580; ENSP00000370992; ENSG00000089012. [Q9P1W8-2]
Ensembl; ENST00000381583; ENSP00000370995; ENSG00000089012. [Q9P1W8-4]
GeneID; 55423; -.
KEGG; hsa:55423; -.
UCSC; uc002wfm.1; human. [Q9P1W8-1]
CTD; 55423; -.
DisGeNET; 55423; -.
GeneCards; SIRPG; -.
HGNC; HGNC:15757; SIRPG.
HPA; ENSG00000089012; Group enriched (blood, lymphoid tissue).
MIM; 605466; gene.
neXtProt; NX_Q9P1W8; -.
OpenTargets; ENSG00000089012; -.
PharmGKB; PA38034; -.
VEuPathDB; HostDB:ENSG00000089012.14; -.
eggNOG; ENOG502S1XD; Eukaryota.
GeneTree; ENSGT00960000186656; -.
HOGENOM; CLU_044430_0_0_1; -.
InParanoid; Q9P1W8; -.
OMA; WLLVDTP; -.
OrthoDB; 904196at2759; -.
PhylomeDB; Q9P1W8; -.
TreeFam; TF341862; -.
PathwayCommons; Q9P1W8; -.
Reactome; R-HSA-202733; Cell surface interactions at the vascular wall.
Reactome; R-HSA-391160; Signal regulatory protein family interactions.
BioGRID-ORCS; 55423; 7 hits in 979 CRISPR screens.
EvolutionaryTrace; Q9P1W8; -.
GeneWiki; SIRPG; -.
GenomeRNAi; 55423; -.
Pharos; Q9P1W8; Tbio.
PRO; PR:Q9P1W8; -.
Proteomes; UP000005640; Chromosome 20.
RNAct; Q9P1W8; protein.
Bgee; ENSG00000089012; Expressed in lymph node and 118 other tissues.
Genevisible; Q9P1W8; HS.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0016020; C:membrane; IDA:UniProtKB.
GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
GO; GO:0008285; P:negative regulation of cell population proliferation; TAS:ProtInc.
GO; GO:0008284; P:positive regulation of cell population proliferation; IDA:UniProtKB.
GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:UniProtKB.
GO; GO:0050766; P:positive regulation of phagocytosis; IBA:GO_Central.
GO; GO:0050870; P:positive regulation of T cell activation; IDA:UniProtKB.
Gene3D; 2.60.40.10; -; 3.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003597; Ig_C1-set.
InterPro; IPR003599; Ig_sub.
InterPro; IPR013106; Ig_V-set.
Pfam; PF07654; C1-set; 2.
Pfam; PF07686; V-set; 1.
SMART; SM00409; IG; 2.
SMART; SM00407; IGc1; 2.
SMART; SM00406; IGv; 1.
SUPFAM; SSF48726; SSF48726; 3.
PROSITE; PS50835; IG_LIKE; 3.
1: Evidence at protein level;
3D-structure; Alternative splicing; Cell adhesion; Disulfide bond;
Glycoprotein; Immunoglobulin domain; Membrane; Reference proteome; Repeat;
Signal; Transmembrane; Transmembrane helix.
SIGNAL 1..28
/evidence="ECO:0000255"
CHAIN 29..387
/note="Signal-regulatory protein gamma"
/id="PRO_0000014957"
TOPO_DOM 29..360
/note="Extracellular"
/evidence="ECO:0000255"
TRANSMEM 361..383
/note="Helical"
/evidence="ECO:0000255"
TOPO_DOM 384..387
/note="Cytoplasmic"
/evidence="ECO:0000255"
DOMAIN 29..137
/note="Ig-like V-type"
DOMAIN 146..245
/note="Ig-like C1-type 1"
DOMAIN 252..340
/note="Ig-like C1-type 2"
CARBOHYD 243
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000269|PubMed:19349973"
CARBOHYD 268
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 309
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 317
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
DISULFID 53..119
/evidence="ECO:0000255|PROSITE-ProRule:PRU00114,
ECO:0000269|PubMed:18657508"
DISULFID 168..226
/evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
DISULFID 271..329
/evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
VAR_SEQ 1..33
/note="Missing (in isoform 2)"
/evidence="ECO:0000303|PubMed:11185750"
/id="VSP_007027"
VAR_SEQ 144..360
/note="Missing (in isoform 3)"
/evidence="ECO:0000303|PubMed:15489334"
/id="VSP_007028"
VAR_SEQ 250..360
/note="Missing (in isoform 4)"
/evidence="ECO:0000303|PubMed:15383453"
/id="VSP_026960"
VARIANT 263
/note="V -> A (in dbSNP:rs6043409)"
/evidence="ECO:0000269|PubMed:11185750"
/id="VAR_049936"
VARIANT 286
/note="S -> L (in dbSNP:rs6034239)"
/evidence="ECO:0000269|PubMed:11185750"
/id="VAR_049937"
STRAND 39..43
/evidence="ECO:0007744|PDB:2JJW"
STRAND 49..51
/evidence="ECO:0007744|PDB:2JJW"
STRAND 54..56
/evidence="ECO:0007744|PDB:2JJW"
STRAND 64..71
/evidence="ECO:0007744|PDB:2JJW"
STRAND 75..82
/evidence="ECO:0007744|PDB:2JJW"
STRAND 88..92
/evidence="ECO:0007744|PDB:2JJW"
STRAND 104..106
/evidence="ECO:0007744|PDB:2JJW"
HELIX 111..113
/evidence="ECO:0007744|PDB:2JJW"
STRAND 115..123
/evidence="ECO:0007744|PDB:2JJW"
STRAND 126..128
/evidence="ECO:0007744|PDB:4I2X"
STRAND 130..134
/evidence="ECO:0007744|PDB:2JJW"
STRAND 138..142
/evidence="ECO:0007744|PDB:2JJW"
STRAND 150..152
/evidence="ECO:0007744|PDB:4I2X"
STRAND 163..176
/evidence="ECO:0007744|PDB:4I2X"
STRAND 179..184
/evidence="ECO:0007744|PDB:4I2X"
STRAND 192..197
/evidence="ECO:0007744|PDB:4I2X"
STRAND 205..214
/evidence="ECO:0007744|PDB:4I2X"
STRAND 223..229
/evidence="ECO:0007744|PDB:4I2X"
TURN 231..235
/evidence="ECO:0007744|PDB:4I2X"
STRAND 238..243
/evidence="ECO:0007744|PDB:4I2X"
HELIX 244..246
/evidence="ECO:0007744|PDB:4I2X"
STRAND 253..260
/evidence="ECO:0007744|PDB:4I2X"
STRAND 262..279
/evidence="ECO:0007744|PDB:4I2X"
STRAND 281..287
/evidence="ECO:0007744|PDB:4I2X"
STRAND 297..302
/evidence="ECO:0007744|PDB:4I2X"
STRAND 308..317
/evidence="ECO:0007744|PDB:4I2X"
STRAND 326..333
/evidence="ECO:0007744|PDB:4I2X"
STRAND 339..344
/evidence="ECO:0007744|PDB:4I2X"
SEQUENCE 387 AA; 42498 MW; 0F5099BE1DE35AC8 CRC64;
MPVPASWPHP PGPFLLLTLL LGLTEVAGEE ELQMIQPEKL LLVTVGKTAT LHCTVTSLLP
VGPVLWFRGV GPGRELIYNQ KEGHFPRVTT VSDLTKRNNM DFSIRISSIT PADVGTYYCV
KFRKGSPENV EFKSGPGTEM ALGAKPSAPV VLGPAARTTP EHTVSFTCES HGFSPRDITL
KWFKNGNELS DFQTNVDPTG QSVAYSIRST ARVVLDPWDV RSQVICEVAH VTLQGDPLRG
TANLSEAIRV PPTLEVTQQP MRVGNQVNVT CQVRKFYPQS LQLTWSENGN VCQRETASTL
TENKDGTYNW TSWFLVNISD QRDDVVLTCQ VKHDGQLAVS KRLALEVTVH QKDQSSDATP
GPASSLTALL LIAVLLGPIY VPWKQKT


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WP244: Alpha 6 Beta 4 signaling pathway
WP560: TGF Beta Signaling Pathway
WP1045: TGF-beta Receptor Signaling Pathway
WP148: Fatty Acid Beta Oxidation 2
WP1690: Propanoate metabolism
WP401: Mitochondrial LC-Fatty Acid Beta-Oxidation
WP842: Signal Transduction of S1P

Related Genes :
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[SIRPA MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[Sirpa Bit Mfr Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[Fcgr2 Fcgr2b Ly-17] Low affinity immunoglobulin gamma Fc region receptor II (Fc gamma receptor IIB) (Fc-gamma RII) (Fc-gamma-RIIB) (FcRII) (IgG Fc receptor II beta) (Lymphocyte antigen 17) (Ly-17) (CD antigen CD32)
[C4B CO4 CPAMD3; C4B_2] Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain]
[PPP2R5C KIAA0044] Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)
[LILRB1 ILT2 LIR1 MIR7] Leukocyte immunoglobulin-like receptor subfamily B member 1 (LIR-1) (Leukocyte immunoglobulin-like receptor 1) (CD85 antigen-like family member J) (Immunoglobulin-like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD antigen CD85j)
[PDGFRB PDGFR PDGFR1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[CD84 SLAMF5] SLAM family member 5 (Cell surface antigen MAX.3) (Hly9-beta) (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)
[LILRB2 ILT4 LIR2 MIR10] Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)
[Pdgfrb Pdgfr Pdgfr1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[Pdgfrb Pdgfr Pdgfr1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[PDGFRB PDGFR PDGFR1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[Rxrb Nr2b2] Retinoic acid receptor RXR-beta (MHC class I regulatory element-binding protein H-2RIIBP) (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta)
[Pre C,C C core E PC pre-C pre-C/C PreC preC PreC/C preC/C precore-core HBVgp4] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[Cd74 Ii] H-2 class II histocompatibility antigen gamma chain (Ia antigen-associated invariant chain) (Ii) (Ii chain) (MHC class II-associated invariant chain) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
[Cd74] H-2 class II histocompatibility antigen gamma chain (Ia antigen-associated invariant chain) (Ii) (MHC class II-associated invariant chain) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
[B2M CDABP0092 HDCMA22P] Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
[CD74 DHLAG] HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
[IL18RAP IL1R7] Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (EC 3.2.2.6) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b)
[MUC1 PUM] Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
[EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1] Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)
[CD69 CLEC2C] Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)
[PPP2R1A] Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
[FCGR2B CD32 FCG2 IGFR2] Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)
[Slc3a2 Mdu1] 4F2 cell-surface antigen heavy chain (4F2hc) (Solute carrier family 3 member 2) (CD antigen CD98)
[KLRD1 CD94] Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
[HSD17B11 DHRS8 PAN1B SDR16C2 PSEC0029 UNQ207/PRO233] Estradiol 17-beta-dehydrogenase 11 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17bHSD11) (17betaHSD11) (17-beta-hydroxysteroid dehydrogenase XI) (17-beta-HSD XI) (17betaHSDXI) (Cutaneous T-cell lymphoma-associated antigen HD-CL-03) (CTCL-associated antigen HD-CL-03) (Dehydrogenase/reductase SDR family member 8) (Retinal short-chain dehydrogenase/reductase 2) (retSDR2) (Short chain dehydrogenase/reductase family 16C member 2)
[C4A CO4 CPAMD2] Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]

Bibliography :