GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)

 TNNT1_RAT               Reviewed;         261 AA.
Q7TNB2; Q7TNA9; Q7TNB0; Q7TNB1; Q923S7;
24-MAY-2005, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 3.
16-JAN-2019, entry version 102.
RecName: Full=Troponin T, slow skeletal muscle;
Short=TnTs;
AltName: Full=Slow skeletal muscle troponin T;
Short=sTnT;
Name=Tnnt1; Synonyms=Fang2;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), AND TISSUE
SPECIFICITY.
STRAIN=Wistar;
PubMed=15788488; DOI=10.1152/ajpcell.00365.2004;
Kischel P., Bastide B., Muller M., Dubail F., Offredi F., Jin J.-P.,
Mounier Y., Martial J.;
"Expression and functional properties of four slow skeletal troponin T
isoforms in rat muscles.";
Am. J. Physiol. 289:C437-C443(2005).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
STRAIN=Sprague-Dawley;
Chang Y.Y., Zuo J.J., Fang F.F.;
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
[3]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=22673903; DOI=10.1038/ncomms1871;
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A.,
Lundby C., Olsen J.V.;
"Quantitative maps of protein phosphorylation sites across 14
different rat organs and tissues.";
Nat. Commun. 3:876-876(2012).
-!- FUNCTION: Troponin T is the tropomyosin-binding subunit of
troponin, the thin filament regulatory complex which confers
calcium-sensitivity to striated muscle actomyosin ATPase activity.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=4;
Name=1; Synonyms=sTnT1;
IsoId=Q7TNB2-1; Sequence=Displayed;
Note=Major.;
Name=2; Synonyms=sTnT2;
IsoId=Q7TNB2-2; Sequence=VSP_013790;
Note=Major.;
Name=3; Synonyms=sTnT3;
IsoId=Q7TNB2-3; Sequence=VSP_013789, VSP_013790;
Note=Minor.;
Name=4; Synonyms=sTnTx;
IsoId=Q7TNB2-4; Sequence=VSP_013789;
Note=Minor.;
-!- TISSUE SPECIFICITY: Expressed in soleus muscle. Isoform 4 is
predominantly expressed in fast muscles.
{ECO:0000269|PubMed:15788488}.
-!- SIMILARITY: Belongs to the troponin T family. {ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=AAK94010.1; Type=Erroneous termination; Positions=229; Note=Translated as Gln.; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AY334079; AAQ19259.1; -; mRNA.
EMBL; AY334080; AAQ19260.1; -; mRNA.
EMBL; AY334081; AAQ19261.1; -; mRNA.
EMBL; AY334082; AAQ19262.1; -; mRNA.
EMBL; AF399874; AAK94010.1; ALT_SEQ; mRNA.
RefSeq; NP_001264189.1; NM_001277260.1. [Q7TNB2-2]
RefSeq; NP_001264190.1; NM_001277261.2. [Q7TNB2-3]
RefSeq; NP_001264191.1; NM_001277262.2. [Q7TNB2-4]
RefSeq; NP_599215.2; NM_134388.2. [Q7TNB2-1]
UniGene; Rn.13846; -.
ProteinModelPortal; Q7TNB2; -.
SMR; Q7TNB2; -.
STRING; 10116.ENSRNOP00000038327; -.
iPTMnet; Q7TNB2; -.
PhosphoSitePlus; Q7TNB2; -.
jPOST; Q7TNB2; -.
PaxDb; Q7TNB2; -.
PRIDE; Q7TNB2; -.
Ensembl; ENSRNOT00000034957; ENSRNOP00000038327; ENSRNOG00000028041. [Q7TNB2-1]
Ensembl; ENSRNOT00000058843; ENSRNOP00000055633; ENSRNOG00000028041. [Q7TNB2-4]
GeneID; 171409; -.
KEGG; rno:171409; -.
UCSC; RGD:621852; rat. [Q7TNB2-1]
CTD; 7138; -.
RGD; 621852; Tnnt1.
eggNOG; KOG3634; Eukaryota.
eggNOG; ENOG410XS6A; LUCA.
GeneTree; ENSGT00940000160609; -.
HOGENOM; HOG000231049; -.
HOVERGEN; HBG052790; -.
InParanoid; Q7TNB2; -.
KO; K10372; -.
OMA; MYQLESE; -.
OrthoDB; 1480247at2759; -.
PhylomeDB; Q7TNB2; -.
Reactome; R-RNO-390522; Striated Muscle Contraction.
PRO; PR:Q7TNB2; -.
Proteomes; UP000002494; Chromosome 1.
Bgee; ENSRNOG00000028041; Expressed in 10 organ(s), highest expression level in skeletal muscle tissue.
Genevisible; Q7TNB2; RN.
GO; GO:0005861; C:troponin complex; IDA:RGD.
GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
GO; GO:0005523; F:tropomyosin binding; IEA:Ensembl.
GO; GO:0031014; F:troponin T binding; IDA:RGD.
GO; GO:0060048; P:cardiac muscle contraction; IBA:GO_Central.
GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
GO; GO:0045932; P:negative regulation of muscle contraction; IEA:Ensembl.
GO; GO:0006937; P:regulation of muscle contraction; IDA:RGD.
GO; GO:0045214; P:sarcomere organization; IBA:GO_Central.
GO; GO:0003009; P:skeletal muscle contraction; IBA:GO_Central.
GO; GO:0031444; P:slow-twitch skeletal muscle fiber contraction; IDA:RGD.
GO; GO:0014883; P:transition between fast and slow fiber; IEA:Ensembl.
Gene3D; 1.20.5.350; -; 1.
InterPro; IPR027707; TNNT.
InterPro; IPR001978; Troponin.
InterPro; IPR038077; Troponin_sf.
PANTHER; PTHR11521; PTHR11521; 1.
Pfam; PF00992; Troponin; 2.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Muscle protein;
Phosphoprotein; Reference proteome.
CHAIN 1 261 Troponin T, slow skeletal muscle.
/FTId=PRO_0000186171.
MOD_RES 2 2 Phosphoserine; by CK2. {ECO:0000250}.
VAR_SEQ 24 34 Missing (in isoform 3 and isoform 4).
{ECO:0000303|PubMed:15788488}.
/FTId=VSP_013789.
VAR_SEQ 35 35 Missing (in isoform 2 and isoform 3).
{ECO:0000303|PubMed:15788488}.
/FTId=VSP_013790.
SEQUENCE 261 AA; 31215 MW; B323364DBCAB5863 CRC64;
MSDTEEQEYE EEQAEDEEAV EEEAPEEPEP VAEREEERPK PSRPVVPPLI PPKIPEGERV
DFDDIHRKRM EKDLLELQTL IDVHFEQRKK EEEELIALKD RIERRRAERA EQQRFRTEKE
RERQAKLAEE KMRKEEEEAK KRAEDDAKKK KVLSNMGAHF GGYLVKAEQK RGKRQTGREM
KLRILSERKK PLNIDYMGED QLREKAQELS EWIHQLESEK FDLMEKLKQQ KYEINVLYNR
ISHAQKFRKG AGKGRVGGRW K


Related products :

Catalog number Product name Quantity
E1820h ELISA Homo sapiens,Human,Slow skeletal muscle troponin T,sTnT,TNNT1,TNT,TnTs,Troponin T, slow skeletal muscle 96T
U1820r CLIA Fang2,Rat,Rattus norvegicus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820r ELISA kit Fang2,Rat,Rattus norvegicus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
U1820h CLIA Homo sapiens,Human,Slow skeletal muscle troponin T,sTnT,TNNT1,TNT,TnTs,Troponin T, slow skeletal muscle 96T
U1820r CLIA kit Fang2,Rat,Rattus norvegicus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820r ELISA Fang2,Rat,Rattus norvegicus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820h ELISA kit Homo sapiens,Human,Slow skeletal muscle troponin T,sTnT,TNNT1,TNT,TnTs,Troponin T, slow skeletal muscle 96T
U1820h CLIA kit Homo sapiens,Human,Slow skeletal muscle troponin T,sTnT,TNNT1,TNT,TnTs,Troponin T, slow skeletal muscle 96T
E1820b ELISA Bos taurus,Bovine,Slow skeletal muscle troponin T,sTnT,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U1820b CLIA kit Bos taurus,Bovine,Slow skeletal muscle troponin T,sTnT,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U1820b CLIA Bos taurus,Bovine,Slow skeletal muscle troponin T,sTnT,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U1820m CLIA Mouse,Mus musculus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820b ELISA kit Bos taurus,Bovine,Slow skeletal muscle troponin T,sTnT,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
E1820m ELISA kit Mouse,Mus musculus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820m ELISA Mouse,Mus musculus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
U1820m CLIA kit Mouse,Mus musculus,Slow skeletal muscle troponin T,sTnT,Tnnt1,TnTs,Troponin T, slow skeletal muscle 96T
E1820p ELISA Pig,Slow skeletal muscle troponin T,sTnT,Sus scrofa,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U1820p CLIA Pig,Slow skeletal muscle troponin T,sTnT,Sus scrofa,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U1820p CLIA kit Pig,Slow skeletal muscle troponin T,sTnT,Sus scrofa,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
E1820p ELISA kit Pig,Slow skeletal muscle troponin T,sTnT,Sus scrofa,TNNT1,TnTs,Troponin T, slow skeletal muscle 96T
U2146r CLIA kit Rat,Rattus norvegicus,Tnni1,Troponin I, slow skeletal muscle,Troponin I, slow-twitch isoform 96T
E2146r ELISA kit Rat,Rattus norvegicus,Tnni1,Troponin I, slow skeletal muscle,Troponin I, slow-twitch isoform 96T
U2146r CLIA Rat,Rattus norvegicus,Tnni1,Troponin I, slow skeletal muscle,Troponin I, slow-twitch isoform 96T
U2146m CLIA Mouse,Mus musculus,Tnni1,Troponin I, slow skeletal muscle,Troponin I, slow-twitch isoform 96T
U2146m CLIA kit Mouse,Mus musculus,Tnni1,Troponin I, slow skeletal muscle,Troponin I, slow-twitch isoform 96T

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Pathways :
WP1088: Striated Muscle Contraction
WP1316: Striated Muscle Contraction
WP1403: AMPK signaling
WP2005: Muscle cell TarBase
WP2118: Arrhythmogenic right ventricular cardiomyopathy
WP216: Striated Muscle Contraction
WP316: Striated Muscle Contraction
WP383: Striated Muscle Contraction
WP745: Striated Muscle Contraction
WP850: Striated Muscle Contraction
WP969: Striated Muscle Contraction
WP1864: Muscle contraction
WP1946: Cori Cycle
WP1991: SRF and miRs in Smooth Muscle Differentiation and Proliferation
WP2012: miRs in Muscle Cell Differentiation
WP2076: miRs in Muscle Cell Differentiation
WP2081: SRF and miRs in Smooth Muscle Differentiation and Proliferation
WP10: IL-9 Signaling Pathway
WP1001: Peptide GPCRs
WP1002: Electron Transport Chain
WP1003: Ovarian Infertility Genes
WP1004: Kit Receptor Signaling Pathway
WP1006: metapathway biotransformation
WP1010: Wnt Signaling Pathway and Pluripotency
WP1011: T Cell Receptor Signaling Pathway

Related Genes :
[TNNT1 TNT] Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)
[TNNT3] Troponin T, fast skeletal muscle (TnTf) (Beta-TnTF) (Fast skeletal muscle troponin T) (fTnT)
[Tnnt3] Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT)
[MYBPC1 MYBPCS] Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)
[TNNI2] Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform)
[TNNT2] Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT)
[ACTA1 ACTA] Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
[Myl2 Mylpc] Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v)
[ATP2A2 ATP2B] Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
[MYL2 MLC2] Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Cardiac myosin light chain 2) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v) (Ventricular myosin light chain 2)
[RYR1 RYDR] Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)
[RYR1] Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)
[GTF2IRD1 CREAM1 GTF3 MUSTRD1 RBAP2 WBSCR11 WBSCR12] General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (General transcription factor III) (MusTRD1/BEN) (Muscle TFII-I repeat domain-containing protein 1) (Slow-muscle-fiber enhancer-binding protein) (USE B1-binding protein) (Williams-Beuren syndrome chromosomal region 11 protein) (Williams-Beuren syndrome chromosomal region 12 protein)
[Myl2 Mlc2] Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v)
[TNNI3 TNNC1] Troponin I, cardiac muscle (Cardiac troponin I)
[Eno3 Eno-3] Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)
[MYL3] Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)
[SCN4A] Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
[ACTA1 ACTA] Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
[PHKA1] Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)
[Acta1 Acta] Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
[Musk Nsk2] Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
[Six4 Arec3] Homeobox protein SIX4 (Sine oculis homeobox homolog 4) (Skeletal muscle-specific ARE-binding protein AREC3)
[Acta1 Acta] Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
[SLC25A4 ANT1] ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4)
[MYH3] Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE)
[ACTA1 ACTA] Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
[Mybpc1] Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform) (Fragment)
[ENO3] Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)
[Eno3 Eno-3] Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)

Bibliography :
[9651500] Three alternatively spliced mouse slow skeletal muscle troponin T isoforms: conserved primary structure and regulated expression during postnatal development.