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Uncharacterized protein

 A0A2I3GKV0_NOMLE        Unreviewed;       295 AA.
A0A2I3GKV0;
28-FEB-2018, integrated into UniProtKB/TrEMBL.
28-FEB-2018, sequence version 1.
05-JUN-2019, entry version 13.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000031892};
Name=CCND1 {ECO:0000313|Ensembl:ENSNLEP00000031892};
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
leucogenys).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hylobatidae; Nomascus.
NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000031892, ECO:0000313|Proteomes:UP000001073};
[1] {ECO:0000313|Ensembl:ENSNLEP00000031892, ECO:0000313|Proteomes:UP000001073}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Gibbon Genome Sequencing Consortium;
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSNLEP00000031892}
IDENTIFICATION.
Ensembl;
Submitted (JAN-2018) to UniProtKB.
-!- SIMILARITY: Belongs to the cyclin family.
{ECO:0000256|RuleBase:RU000383, ECO:0000256|SAAS:SAAS00861960}.
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EMBL; ADFV01104675; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_003278068.1; XM_003278020.3.
Ensembl; ENSNLET00000047321; ENSNLEP00000031892; ENSNLEG00000029930.
GeneID; 100605736; -.
KEGG; nle:100605736; -.
CTD; 595; -.
GeneTree; ENSGT00940000157816; -.
KO; K04503; -.
OMA; YRTTHFL; -.
OrthoDB; 1234739at2759; -.
Proteomes; UP000001073; Chromosome 4.
GO; GO:0005923; C:bicellular tight junction; IEA:Ensembl.
GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IEA:Ensembl.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0017053; C:transcriptional repressor complex; IEA:Ensembl.
GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:Ensembl.
GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
GO; GO:0070064; F:proline-rich region binding; IEA:Ensembl.
GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
GO; GO:0007595; P:lactation; IEA:Ensembl.
GO; GO:0097421; P:liver regeneration; IEA:Ensembl.
GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IEA:Ensembl.
GO; GO:0071157; P:negative regulation of cell cycle arrest; IEA:Ensembl.
GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:0045737; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
GO; GO:0000320; P:re-entry into mitotic cell cycle; IEA:Ensembl.
GO; GO:0042493; P:response to drug; IEA:Ensembl.
GO; GO:0044321; P:response to leptin; IEA:Ensembl.
GO; GO:0070141; P:response to UV-A; IEA:Ensembl.
GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
CDD; cd00043; CYCLIN; 1.
InterPro; IPR039361; Cyclin.
InterPro; IPR013763; Cyclin-like.
InterPro; IPR036915; Cyclin-like_sf.
InterPro; IPR004367; Cyclin_C-dom.
InterPro; IPR015451; Cyclin_D.
InterPro; IPR006671; Cyclin_N.
PANTHER; PTHR10177; PTHR10177; 1.
PANTHER; PTHR10177:SF67; PTHR10177:SF67; 1.
Pfam; PF02984; Cyclin_C; 1.
Pfam; PF00134; Cyclin_N; 1.
PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
SMART; SM00385; CYCLIN; 1.
SMART; SM01332; Cyclin_C; 1.
SUPFAM; SSF47954; SSF47954; 2.
PROSITE; PS00292; CYCLINS; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000001073};
Cyclin {ECO:0000256|RuleBase:RU000383, ECO:0000256|SAAS:SAAS00862020};
Reference proteome {ECO:0000313|Proteomes:UP000001073}.
DOMAIN 57 88 Cyclin N-terminal.
{ECO:0000259|PROSITE:PS00292}.
REGION 262 295 Disordered. {ECO:0000256|MobiDB-
lite:A0A2I3GKV0}.
SEQUENCE 295 AA; 33715 MW; 2721B282A55E969A CRC64;
MEHQLLCCEV ETIRRAYPDA NLLNDRVLRA MLKAEETCAP SVSYFKCVQK EVLPSMRKIV
ATWMLEVCEE QKCEEDVFPL AMNYLDRFLS LEPVKKSRLQ LLGATCMFVA SKMKETIPLT
AEKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE AEENKQIIRK
HAQTFVALCA TDVKFISNPP SMVAAGSVVA AVQGLNLRSP NNFLSYYRLT RFLSRVIKCD
PDCLRACQEQ IEALLESSLR QAQQNMDPKA AEEEEEEEEE VDLACTPTDV RDVDI


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