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Uncharacterized protein

 A0A2K5NB38_CERAT        Unreviewed;       295 AA.
A0A2K5NB38;
28-MAR-2018, integrated into UniProtKB/TrEMBL.
28-MAR-2018, sequence version 1.
05-JUN-2019, entry version 12.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCATP00000034707};
Name=CCND1 {ECO:0000313|Ensembl:ENSCATP00000034707};
Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus.
NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000034707, ECO:0000313|Proteomes:UP000233060};
[1] {ECO:0000313|Ensembl:ENSCATP00000034707, ECO:0000313|Proteomes:UP000233060}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Liu Y., Hughes D.S., Murali S., Raveendran M., Korchina V., Wang M.,
Jhangiani S., Bandaranaike D., Bellair M., Blankenburg K., Chao H.,
Dahdouli M., Dinh H., Doddapaneni H., English A., Firestine M.,
Gross S., Hernandez B., Javaid M., Jayaseelan J., Jones J., Joshi V.,
Khan Z., Kovar C., Lee S., Newsham I., Nguyen L., Okwuonu G.,
Ongeri F., Osuji N., Pu L.-L., Puazo M., Qu C., Quiroz J., Raj R.,
Reid J.G., Santibanez J., Scheel M., Sexton D., Shah N., Skinner E.,
Vee V., Wu Y., Han Y., Muzny D.M., Richards S., Worley K.C.,
Rogers J., Gibbs R.A.;
"Sooty reference genome and diversity panel.";
Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSCATP00000034707}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2018) to UniProtKB.
-!- SIMILARITY: Belongs to the cyclin family.
{ECO:0000256|RuleBase:RU000383, ECO:0000256|SAAS:SAAS00861960}.
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RefSeq; XP_011896723.1; XM_012041333.1.
Ensembl; ENSCATT00000058988; ENSCATP00000034707; ENSCATG00000040258.
GeneID; 105577306; -.
CTD; 595; -.
GeneTree; ENSGT00940000157816; -.
OrthoDB; 1234739at2759; -.
Proteomes; UP000233060; Whole Genome Shotgun Assembly.
GO; GO:0005923; C:bicellular tight junction; IEA:Ensembl.
GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IEA:Ensembl.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0017053; C:transcriptional repressor complex; IEA:Ensembl.
GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:Ensembl.
GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
GO; GO:0070064; F:proline-rich region binding; IEA:Ensembl.
GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
GO; GO:0007595; P:lactation; IEA:Ensembl.
GO; GO:0097421; P:liver regeneration; IEA:Ensembl.
GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IEA:Ensembl.
GO; GO:0071157; P:negative regulation of cell cycle arrest; IEA:Ensembl.
GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:0045737; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
GO; GO:0000320; P:re-entry into mitotic cell cycle; IEA:Ensembl.
GO; GO:0042493; P:response to drug; IEA:Ensembl.
GO; GO:0044321; P:response to leptin; IEA:Ensembl.
GO; GO:0070141; P:response to UV-A; IEA:Ensembl.
GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
CDD; cd00043; CYCLIN; 1.
InterPro; IPR039361; Cyclin.
InterPro; IPR013763; Cyclin-like.
InterPro; IPR036915; Cyclin-like_sf.
InterPro; IPR004367; Cyclin_C-dom.
InterPro; IPR015451; Cyclin_D.
InterPro; IPR006671; Cyclin_N.
PANTHER; PTHR10177; PTHR10177; 1.
PANTHER; PTHR10177:SF67; PTHR10177:SF67; 1.
Pfam; PF02984; Cyclin_C; 1.
Pfam; PF00134; Cyclin_N; 1.
PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
SMART; SM00385; CYCLIN; 1.
SMART; SM01332; Cyclin_C; 1.
SUPFAM; SSF47954; SSF47954; 2.
PROSITE; PS00292; CYCLINS; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000233060};
Cyclin {ECO:0000256|RuleBase:RU000383, ECO:0000256|SAAS:SAAS00862020};
Reference proteome {ECO:0000313|Proteomes:UP000233060}.
DOMAIN 57 88 Cyclin N-terminal.
{ECO:0000259|PROSITE:PS00292}.
REGION 262 295 Disordered. {ECO:0000256|MobiDB-
lite:A0A2K5NB38}.
SEQUENCE 295 AA; 33611 MW; 322F5D3CF0059C3B CRC64;
MEHQLLCCEV ETIRRAYPDA NLLNDRVLRA MLKAEETCAP SVSYFKCVQK EVLPSMRKIV
ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPVKKSRLQ LLGATCMFVA SKMKETIPLT
AEKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE AEENKQIIRK
HAQTFVALCA TDVKFISNPP SMVAAGSVVA AVQGLNLGSP NNFLSYYRLT HFLSRVIKCD
PDCLRACQEQ IEALLESSLR QAQQNMDPKA AEEEEEEEEE VDLACTPTDV RDVDI


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Pathways :
WP834: Cytoplasmic Ribosomal Proteins
WP1371: G Protein Signaling Pathways
WP1888: Post-translational protein modification
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WP1663: Homologous recombination
WP35: G Protein Signaling Pathways
WP1673: Naphthalene and anthracene degradation
WP731: Sterol regulatory element binding protein related
WP1502: Mitochondrial biogenesis
WP1939: Unfolded Protein Response
WP1853: Metabolism of proteins
WP1613: 1,4-Dichlorobenzene degradation
WP211: BMP signaling pathway
WP1902: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
WP1678: Nucleotide excision repair
WP1929: Thrombin signalling through proteinase activated receptors (PARs)
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[C1orf109] Uncharacterized protein C1orf109
[C1orf94] Uncharacterized protein C1orf94
[1070] Uncharacterized protein 1070
[SPBC902.06] Uncharacterized protein C902.06
[SPAC17H9.02] Uncharacterized helicase C17H9.02 (EC 3.6.4.-)
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[CHMP3 CGI149 NEDF VPS24 CGI-149] Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
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[31324866] Large-scale Discovery of Substrates of the Human Kinome.
[31323128] Molecular Determinants of Complex Formation between DNA and the AT-rich Interaction Domain of BAF250a.
[31314595] A novel mutation in gene causes a severe neurodevelopmental delay due to mitochondrial dysfunction with complex I impairments and altered pyruvate metabolism.
[31311847] Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer.
[31308252] Small-protein enrichment assay enables the rapid, unbiased analysis of over 100 low abundance factors from human plasma.
[31301291] LRRC62 attenuates Toll-like receptor signaling by deubiquitinating TAK1 via CYLD.
[31301270] HprK is a serine kinase that regulates virulence in the Gram-negative phytopathogen Xanthomonas campestris.
[31299006] Evolution, purification, and characterization of RC0497: a peptidoglycan amidase from the prototypical spotted fever species Rickettsia conorii.
[31298437] Discovery of Receptor-Ligand Interfaces in the Immunoglobulin Superfamily.