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Uncharacterized protein

 A0A452E7E5_CAPHI        Unreviewed;       433 AA.
08-MAY-2019, integrated into UniProtKB/TrEMBL.
08-MAY-2019, sequence version 1.
12-AUG-2020, entry version 8.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCHIP00000007888};
Name=SPRED1 {ECO:0000313|Ensembl:ENSCHIP00000007888};
Capra hircus (Goat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
Caprinae; Capra.
NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000007888};
[1] {ECO:0000313|Ensembl:ENSCHIP00000007888}
Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
Phillippy A.M., Van Tassell C.P., Smith T.P.;
"Polished mammalian reference genomes with single-molecule sequencing and
chromosome conformation capture applied to the Capra hircus genome.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSCHIP00000007888}
Submitted (MAR-2019) to UniProtKB.
Copyrighted by the UniProt Consortium, see
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; LWLT01000010; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Ensembl; ENSCHIT00000015639; ENSCHIP00000007888; ENSCHIG00000011243.
GeneTree; ENSGT00940000159180; -.
Proteomes; UP000291000; Chromosome 10.
GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0016020; C:membrane; IEA:InterPro.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0019902; F:phosphatase binding; IEA:Ensembl.
GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; IEA:Ensembl.
GO; GO:0005173; F:stem cell factor receptor binding; IEA:Ensembl.
GO; GO:0000188; P:inactivation of MAPK activity; IEA:Ensembl.
GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IEA:Ensembl.
GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IEA:Ensembl.
GO; GO:0010923; P:negative regulation of phosphatase activity; IEA:Ensembl.
GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl.
GO; GO:0090311; P:regulation of protein deacetylation; IEA:Ensembl.
GO; GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; IEA:Ensembl.
CDD; cd10574; EVH1_SPRED-like; 1.
Gene3D;; -; 1.
InterPro; IPR023337; KBD.
InterPro; IPR011993; PH-like_dom_sf.
InterPro; IPR041937; SPRE_EVH1.
InterPro; IPR007875; Sprouty.
InterPro; IPR000697; WH1/EVH1_dom.
Pfam; PF05210; Sprouty; 1.
Pfam; PF00568; WH1; 1.
SMART; SM00461; WH1; 1.
PROSITE; PS51488; KBD; 1.
PROSITE; PS51227; SPR; 1.
PROSITE; PS50229; WH1; 1.
4: Predicted;
Membrane {ECO:0000256|ARBA:ARBA00023136};
Reference proteome {ECO:0000313|Proteomes:UP000291000}.
DOMAIN 1..113
DOMAIN 222..274
REGION 256..277
COMPBIAS 256..273
SEQUENCE 433 AA; 49296 MW; 504151A453387028 CRC64;

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EIAAB07568 Ag2,Protein Ag2,Rat,Rattus norvegicus,Uncharacterized protein C11orf96 homolog
EIAAB07548 Mouse,Mus musculus,Nwc,Protein NWC,Uncharacterized protein C11orf74 homolog
EIAAB06945 Nod3l,NOD3-like protein,Rat,Rattus norvegicus,Uncharacterized protein C6orf154 homolog
EIAAB06257 Mouse,Mus musculus,Osap,Ovary-specific acidic protein,Uncharacterized protein C4orf49 homolog
EIAAB07500 Mouse,Mus musculus,Oocyte-testis gene 1 protein,Otg1,Uncharacterized protein C10orf118 homolog
EIAAB06256 Bos taurus,Bovine,OSAP,Ovary-specific acidic protein,Uncharacterized protein C4orf49 homolog
EIAAB10025 Mouse,Mus musculus,Testis-specific expressed protein 2,TSEG2,TSEG-2,Uncharacterized protein C22orf41 homolog
EIAAB07459 Kiaa2006,Mouse,Mus musculus,Pap20,Peripheral benzodiazepine receptor-associated protein 20,Uncharacterized protein C10orf18 homolog
EIAAB07546 L7rn6,Lethal gene on chromosome 7 Rinchik 6 protein,Mouse,Mus musculus,Uncharacterized protein C11orf73 homolog
EIAAB07317 Mouse,Mus musculus,Smrp1,Spermatid-specific manchette-related protein 1,Uncharacterized protein C9orf24 homolog
EIAAB08112 C14orf162,Homo sapiens,Human,Myelin proteolipid protein-like protein,PLPL,Uncharacterized protein C14orf162
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18-003-44025 Uncharacterized protein KIAA1849 - N_A Polyclonal 0.1 mg Protein A
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Pathways :
WP1049: G Protein Signaling Pathways
WP1713: Two-component system
WP163: Cytoplasmic Ribosomal Proteins
WP1659: Glycine, serine and threonine metabolism
WP2371: Parkinsons Disease Pathway
WP540: Cytoplasmic Ribosomal Proteins
WP1665: Limonene and pinene degradation
WP525: Mitochondrial Unfolded-Protein Response
WP914: NLR proteins
WP1438: Influenza A virus infection
WP1892: Protein folding
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP2032: TSH signaling pathway
WP1887: Post-translational modification: synthesis of GPI-anchored proteins
WP1675: Nitrogen metabolism
WP813: G Protein Signaling Pathways
WP1531: Vitamin D synthesis
WP1032: NLR proteins
WP1616: ABC transporters
WP2199: Seed Development
WP1963: The effect of Glucocorticoids on target gene expression
WP1685: Peptidoglycan biosynthesis
WP288: NLR proteins
WP1692: Protein export
WP1239: Cytoplasmic Ribosomal Proteins

Related Genes :
[C4orf3] Uncharacterized protein C4orf3 (Hepatitis C virus F protein-transactivated protein 1) (HCV F-transactivated protein 1)
[NKAPD1 C11orf57] Uncharacterized protein NKAPD1 (NKAP domain containing protein 1)
[C14orf119 My028] Uncharacterized protein C14orf119
[C10orf55] Uncharacterized protein C10orf55
[C1orf94] Uncharacterized protein C1orf94
[C1orf109] Uncharacterized protein C1orf109
[C19orf57] Uncharacterized protein C19orf57 (Pre-T/NK cell-associated protein 3B3)
[1070] Uncharacterized protein 1070
[SPAC17H9.02] Uncharacterized helicase C17H9.02 (EC 3.6.4.-)
[C4orf45] Uncharacterized protein C4orf45
[C11orf87] Uncharacterized protein C11orf87
[IRC20 YLR247C] Uncharacterized ATP-dependent helicase IRC20 (EC 3.6.1.-) (Increased recombination centers protein 20)
[SBK3 SGK110] Uncharacterized serine/threonine-protein kinase SBK3 (EC (SH3-binding domain kinase family member 3) (Sugen kinase 110)
[Stg] Uncharacterized protein C6orf15 homolog (Extracellular matrix protein with prion homology) (Emprin) (Protein STG)
[SPBC902.06] Uncharacterized protein C902.06
[C20orf85] Uncharacterized protein C20orf85
[] Genome polyprotein [Cleaved into: Protein p11; Protein p28; NTPase (EC (p35); Protein p32; Viral genome-linked protein (VPg) (p14); Protease-polymerase p70 (Pro-Pol) (EC (EC; Capsid protein (CP) (VP1) (p60)]
[hexB DOTSEDRAFT_181128] Fatty acid synthase beta subunit hexB (EC (S-acyl fatty acid synthase thioesterase) (EC [Includes: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC; Enoyl-[acyl-carrier-protein] reductase [NADH] (EC; [Acyl-carrier-protein] acetyltransferase (EC; [Acyl-carrier-protein] malonyltransferase (EC (Dothistromin biosynthesis protein hexB)]
[ORF1] Genome polyprotein [Cleaved into: Protein p28; NTPase (EC (p35); Protein p32; Viral genome-linked protein (VPg) (p14); Protease-polymerase p70 (Pro-Pol) (EC (EC; Capsid protein (CP) (VP1) (p60)] (Fragment)
[CHMP3 CGI149 NEDF VPS24 CGI-149] Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
[CHMP2A BC2 CHMP2] Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
[] Methyltransferase/RNA helicase (EC (Replicase large subunit) (Replicase small subunit)
[DCUN1D3 SCCRO3] DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3)
[CTDSPL C3orf8 NIF1 NIFL SCP3 YA22] CTD small phosphatase-like protein (CTDSP-like) (EC (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)
[C7orf31] Uncharacterized protein C7orf31
[smpB smqB b2620 JW2601] SsrA-binding protein (Small protein B)
[Slc27a4 Acsvl4 Fatp4] Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.-) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4)
[NBA1 YOL070C] Protein NBA1 (NAP1 and bud neck-associated protein 1)
[VTC1 NRF1 PHM4 YER072W] Vacuolar transporter chaperone 1 (Negative regulator of CDC42 protein 1) (Phosphate metabolism protein 4)
[C10orf67 LINC01552] Uncharacterized protein C10orf67, mitochondrial

Bibliography :
[32948902] The Arabidopsis KH-domain protein FLOWERING LOCUS Y delays flowering by upregulating FLOWERING LOCUS C family members.
[32946437] Transcriptomic profiling of the digestive tract of the rat flea, Xenopsylla cheopis, following blood feeding and infection with Yersinia pestis.
[32943632] Exploiting biofilm phenotypes for functional characterization of hypothetical genes in Enterococcus faecalis.
[32938958] Activity-based protein profiling of rice (Oryza sativa L.) bran serine hydrolases.
[32937585] DNB-based on-chip motif finding: A high-throughput method to profile different types of protein-DNA interactions.
[32937101] Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-Dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase.
[32933572] Identification and characterization a novel polar tube protein (NbPTP6) from the microsporidian Nosema bombycis.
[32929263] Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.
[32929011] PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition.
[32927165] Preserved antibacterial activity of ribosomal protein S15 during evolution.