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Uncharacterized protein

 A0A5F8A6K8_MACMU        Unreviewed;       189 AA.
A0A5F8A6K8;
11-DEC-2019, integrated into UniProtKB/TrEMBL.
11-DEC-2019, sequence version 1.
17-JUN-2020, entry version 4.
SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000072591};
Name=IFNA10 {ECO:0000313|Ensembl:ENSMMUP00000072591};
Macaca mulatta (Rhesus macaque).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
Cercopithecidae; Cercopithecinae; Macaca.
NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000072591, ECO:0000313|Proteomes:UP000006718};
[1] {ECO:0000313|Ensembl:ENSMMUP00000072591, ECO:0000313|Proteomes:UP000006718}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000072591,
ECO:0000313|Proteomes:UP000006718};
PubMed=17431167; DOI=10.1126/science.1139247;
Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
Kuhn R.M., Smith K.E., Zwieg A.S.;
"Evolutionary and biomedical insights from the rhesus macaque genome.";
Science 316:222-234(2007).
[2] {ECO:0000313|Ensembl:ENSMMUP00000072591}
IDENTIFICATION.
STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000072591};
Ensembl;
Submitted (OCT-2019) to UniProtKB.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00135286}.
-!- SIMILARITY: Belongs to the alpha/beta interferon family.
{ECO:0000256|RuleBase:RU000436, ECO:0000256|SAAS:SAAS00562792}.
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RefSeq; NP_001181313.1; NM_001194384.1.
Ensembl; ENSMMUT00000094914; ENSMMUP00000072591; ENSMMUG00000058565.
GeneID; 710654; -.
KEGG; mcc:710654; -.
CTD; 3446; -.
GeneTree; ENSGT00950000182853; -.
KO; K05414; -.
OMA; RKYSPCA; -.
Proteomes; UP000006718; Chromosome 15.
GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
CDD; cd00095; IFab; 1.
InterPro; IPR009079; 4_helix_cytokine-like_core.
InterPro; IPR000471; Interferon_alpha/beta/delta.
PANTHER; PTHR11691; PTHR11691; 1.
Pfam; PF00143; Interferon; 1.
PRINTS; PR00266; INTERFERONAB.
SMART; SM00076; IFabd; 1.
SUPFAM; SSF47266; SSF47266; 1.
PROSITE; PS00252; INTERFERON_A_B_D; 1.
3: Inferred from homology;
Antiviral defense {ECO:0000256|RuleBase:RU000436,
ECO:0000256|SAAS:SAAS00135290};
Cytokine {ECO:0000256|RuleBase:RU000436, ECO:0000256|SAAS:SAAS00135284};
Disulfide bond {ECO:0000256|SAAS:SAAS00487274};
Reference proteome {ECO:0000313|Proteomes:UP000006718};
Secreted {ECO:0000256|SAAS:SAAS00487273}; Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1..23
/evidence="ECO:0000256|SAM:SignalP"
CHAIN 24..189
/evidence="ECO:0000256|SAM:SignalP"
/id="PRO_5023833175"
SEQUENCE 189 AA; 21621 MW; C7CF1B48CFD044C8 CRC64;
MALSFSLLMA VVVLSYKSIC SLGCDLPQTH SLGNRRALIL LAQMGRISPF SCLKDRHDFG
FPQEEFDGNQ FQTAQAMSVL HEMIQQTFNL FSTKDSSAAW EQNLLEKFST ELYQQLSDLE
ACVIQEAGVG ETPLMNEDSI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSLSFSTN
LQKRLRKKN


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[32737119] Selective Disruption of Synaptic BMP Signaling by a Smad Mutation Adjacent to the Highly Conserved H2 Helix.
[32736701] Megalin-mediated albumin endocytosis in cultured murine mesangial cells.
[32736135] Analysis of the proteins secreted by Trichoderma harzianum P49P11 under carbon-limited conditions.
[32736071] Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59.
[32729375] Characterization of a novel class of glyoxylate reductase belonging to the β-hydroxyacid dehydrogenase family in .
[32728046] An integrative ENCODE resource for cancer genomics.
[32726085] Understanding the Early Biological Effects of Isoprene-Derived Particulate Matter Enhanced by Anthropogenic Pollutants.
[32722163] A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection.
[32714146] LMTK1, a Novel Modulator of Endosomal Trafficking in Neurons.
[32713858] PRIGSA2: Improved version of protein repeat identification by graph spectral analysis.