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Uncharacterized protein

 M3YTF0_MUSPF            Unreviewed;       725 AA.
M3YTF0;
01-MAY-2013, integrated into UniProtKB/TrEMBL.
01-MAY-2013, sequence version 1.
26-FEB-2020, entry version 48.
SubName: Full=Phosphoinositide-3-kinase regulatory subunit 1 {ECO:0000313|Ensembl:ENSMPUP00000014610};
Name=PIK3R1 {ECO:0000313|Ensembl:ENSMPUP00000014610};
Mustela putorius furo (European domestic ferret) (Mustela furo).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Mustelinae;
Mustela.
NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000014610, ECO:0000313|Proteomes:UP000000715};
[1] {ECO:0000313|Ensembl:ENSMPUP00000014610}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ID#1420 {ECO:0000313|Ensembl:ENSMPUP00000014610};
Di Palma F., Alfoldi J., Johnson J., Jaffe D., Berlin A., Gnerre S.,
Grabherr M., Hall G., Lara M., MacCallum I., Mauceli E., Przyblyski D.,
Ribeiro F., Russell P., Sharpe T., Turner-Maier J., Walker B.J., Young S.,
Birren B., Lindblad-Toh K.;
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSMPUP00000014610}
IDENTIFICATION.
Ensembl;
Submitted (MAR-2013) to UniProtKB.
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EMBL; AEYP01061723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AEYP01061724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_004764567.1; XM_004764510.2.
STRING; 9668.ENSMPUP00000014610; -.
Ensembl; ENSMPUT00000014843; ENSMPUP00000014610; ENSMPUG00000014719.
GeneID; 101683710; -.
CTD; 5295; -.
eggNOG; KOG4637; Eukaryota.
eggNOG; ENOG410XP6R; LUCA.
GeneTree; ENSGT00940000155553; -.
HOGENOM; CLU_007031_1_0_1; -.
InParanoid; M3YTF0; -.
OMA; TEWSERQ; -.
Proteomes; UP000000715; Unassembled WGS sequence.
GO; GO:0005623; C:cell; IEA:GOC.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0005801; C:cis-Golgi network; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:1990578; C:perinuclear endoplasmic reticulum membrane; IEA:Ensembl.
GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
GO; GO:0043125; F:ErbB-3 class receptor binding; IEA:Ensembl.
GO; GO:0043559; F:insulin binding; IEA:Ensembl.
GO; GO:0005158; F:insulin receptor binding; IEA:Ensembl.
GO; GO:0043560; F:insulin receptor substrate binding; IEA:Ensembl.
GO; GO:0005159; F:insulin-like growth factor receptor binding; IEA:Ensembl.
GO; GO:0005168; F:neurotrophin TRKA receptor binding; IEA:Ensembl.
GO; GO:0036312; F:phosphatidylinositol 3-kinase regulatory subunit binding; IEA:Ensembl.
GO; GO:0001784; F:phosphotyrosine residue binding; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0019903; F:protein phosphatase binding; IEA:Ensembl.
GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
GO; GO:0001678; P:cellular glucose homeostasis; IEA:Ensembl.
GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
GO; GO:0060396; P:growth hormone receptor signaling pathway; IEA:Ensembl.
GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
GO; GO:0033120; P:positive regulation of RNA splicing; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
GO; GO:0046626; P:regulation of insulin receptor signaling pathway; IEA:Ensembl.
GO; GO:1903076; P:regulation of protein localization to plasma membrane; IEA:Ensembl.
GO; GO:0051492; P:regulation of stress fiber assembly; IEA:Ensembl.
GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
CDD; cd09930; SH2_cSH2_p85_like; 1.
CDD; cd09942; SH2_nSH2_p85_like; 1.
CDD; cd11910; SH3_PI3K_p85alpha; 1.
Gene3D; 1.10.555.10; -; 1.
Gene3D; 3.30.505.10; -; 2.
InterPro; IPR032498; PI3K_P85_iSH2.
InterPro; IPR035591; PI3K_p85alpha_SH3.
InterPro; IPR035020; PI3kinase_P85_cSH2.
InterPro; IPR035022; PI3kinase_P85_nSH2.
InterPro; IPR008936; Rho_GTPase_activation_prot.
InterPro; IPR000198; RhoGAP_dom.
InterPro; IPR000980; SH2.
InterPro; IPR036860; SH2_dom_sf.
InterPro; IPR036028; SH3-like_dom_sf.
InterPro; IPR001452; SH3_domain.
Pfam; PF16454; PI3K_P85_iSH2; 1.
Pfam; PF00620; RhoGAP; 1.
Pfam; PF00017; SH2; 2.
PRINTS; PR00401; SH2DOMAIN.
SMART; SM00324; RhoGAP; 1.
SMART; SM00252; SH2; 2.
SMART; SM00326; SH3; 1.
SUPFAM; SSF48350; SSF48350; 1.
SUPFAM; SSF50044; SSF50044; 1.
SUPFAM; SSF55550; SSF55550; 2.
PROSITE; PS50238; RHOGAP; 1.
PROSITE; PS50001; SH2; 2.
PROSITE; PS50002; SH3; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Reference proteome {ECO:0000313|Proteomes:UP000000715};
SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192,
ECO:0000256|SAAS:SAAS01042643}.
DOMAIN 3..79
/note="SH3"
/evidence="ECO:0000259|PROSITE:PS50002"
DOMAIN 114..302
/note="Rho-GAP"
/evidence="ECO:0000259|PROSITE:PS50238"
DOMAIN 334..429
/note="SH2"
/evidence="ECO:0000259|PROSITE:PS50001"
DOMAIN 625..719
/note="SH2"
/evidence="ECO:0000259|PROSITE:PS50001"
REGION 80..111
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COILED 450..470
/evidence="ECO:0000256|SAM:Coils"
COILED 515..563
/evidence="ECO:0000256|SAM:Coils"
COMPBIAS 84..98
/note="Pro-rich"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 725 AA; 83772 MW; CFBCA66465196C89 CRC64;
MSAEGYQYRA LYDYKKERDE DIDLHLGDVL TVNKGSLVAL GFSDGQEARP EEIGWLNGYN
ETTGERGDFP GTYVEYIGRK RISPPTPKPR PPRPLPVAPG SSKAEADSEQ QQALALPDLA
EQFAPPDIAP PLLVKLLEAI EKKGLECSTL YRTQSSSNPA ELRQLLDCDA ASMDLEMIDV
QVLGDAFKRY LMDLPNPVIP VAVYNEMIYL AQEVQSSEDY IQLLKKLIRA PNIPHQYWLT
LQYLLKHFFK LCQTSSKNLL SARVLSELFS PLLFRFPAAS SENTEHLIKV IEILISTEWN
ERQPAPALPP KPPKPTSVAN NGMNNNMSLQ DAEWYWGDIS REEVNEKLRD TADGTFLVRD
ASTKMHGDYT LTLRKGGNNK LIKIFHRDGK YGFSDPLTFN SVVELINHYR NESLAQYNPK
LDVKLLYPVS KYQQDQVVKE DNIEAVGKKL HEYNTQFQEK SREYDRLYED YTRTSQEIQM
KRTAIEAFNE TIKIFEEQCQ SQERYSKEYI EKFKREGNEK EIQRIMHNYE KLKSRISEIV
DSRRRLEEDL KKQAAEYREI DKRMNSIKPD LIQLRKTRDQ YLMWLTQKGV RQKKLNEWLG
NENTEDQYSL VEDDEDLPHH DEKTWNVGSS NRNKAENLLR GKRDGTFLVR ESSKQGCYAC
SVVVDGEVKH CVINKTATGY GFAEPYNLYS SLKELVLHYQ HTSLVQHNDS LNVTLAYPVY
AQQRR


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18-003-44025 Uncharacterized protein KIAA1849 - N_A Polyclonal 0.1 mg Protein A
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Pathways :
WP2371: Parkinsons Disease Pathway
WP540: Cytoplasmic Ribosomal Proteins
WP1049: G Protein Signaling Pathways
WP1713: Two-component system
WP163: Cytoplasmic Ribosomal Proteins
WP1659: Glycine, serine and threonine metabolism
WP1892: Protein folding
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP1665: Limonene and pinene degradation
WP525: Mitochondrial Unfolded-Protein Response
WP914: NLR proteins
WP1438: Influenza A virus infection
WP813: G Protein Signaling Pathways
WP1531: Vitamin D synthesis
WP2032: TSH signaling pathway
WP1887: Post-translational modification: synthesis of GPI-anchored proteins
WP1675: Nitrogen metabolism
WP1963: The effect of Glucocorticoids on target gene expression
WP1685: Peptidoglycan biosynthesis
WP1032: NLR proteins
WP1616: ABC transporters
WP2199: Seed Development
WP1644: DNA replication
WP2272: Pathogenic Escherichia coli infection
WP288: NLR proteins

Related Genes :
[C4orf3] Uncharacterized protein C4orf3 (Hepatitis C virus F protein-transactivated protein 1) (HCV F-transactivated protein 1)
[NKAPD1 C11orf57] Uncharacterized protein NKAPD1 (NKAP domain containing protein 1)
[C14orf119 My028] Uncharacterized protein C14orf119
[C10orf55] Uncharacterized protein C10orf55
[C1orf94] Uncharacterized protein C1orf94
[C1orf109] Uncharacterized protein C1orf109
[C19orf57] Uncharacterized protein C19orf57 (Pre-T/NK cell-associated protein 3B3)
[1070] Uncharacterized protein 1070
[SPAC17H9.02] Uncharacterized helicase C17H9.02 (EC 3.6.4.-)
[C4orf45] Uncharacterized protein C4orf45
[IRC20 YLR247C] Uncharacterized ATP-dependent helicase IRC20 (EC 3.6.1.-) (Increased recombination centers protein 20)
[C11orf87] Uncharacterized protein C11orf87
[SBK3 SGK110] Uncharacterized serine/threonine-protein kinase SBK3 (EC 2.7.11.1) (SH3-binding domain kinase family member 3) (Sugen kinase 110)
[SPBC902.06] Uncharacterized protein C902.06
[Stg] Uncharacterized protein C6orf15 homolog (Extracellular matrix protein with prion homology) (Emprin) (Protein STG)
[C20orf85] Uncharacterized protein C20orf85
[] Genome polyprotein [Cleaved into: Protein p11; Protein p28; NTPase (EC 3.6.1.15) (p35); Protein p32; Viral genome-linked protein (VPg) (p14); Protease-polymerase p70 (Pro-Pol) (EC 2.7.7.48) (EC 3.4.22.66); Capsid protein (CP) (VP1) (p60)]
[hexB DOTSEDRAFT_181128] Fatty acid synthase beta subunit hexB (EC 2.3.1.86) (S-acyl fatty acid synthase thioesterase) (EC 3.1.2.14) [Includes: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9); [Acyl-carrier-protein] acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] malonyltransferase (EC 2.3.1.39) (Dothistromin biosynthesis protein hexB)]
[ORF1] Genome polyprotein [Cleaved into: Protein p28; NTPase (EC 3.6.1.15) (p35); Protein p32; Viral genome-linked protein (VPg) (p14); Protease-polymerase p70 (Pro-Pol) (EC 2.7.7.48) (EC 3.4.22.66); Capsid protein (CP) (VP1) (p60)] (Fragment)
[CHMP3 CGI149 NEDF VPS24 CGI-149] Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
[CHMP2A BC2 CHMP2] Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
[DCUN1D3 SCCRO3] DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3)
[CTDSPL C3orf8 NIF1 NIFL SCP3 YA22] CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)
[smpB smqB b2620 JW2601] SsrA-binding protein (Small protein B)
[Slc27a4 Acsvl4 Fatp4] Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.-) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4)
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[VTC1 NRF1 PHM4 YER072W] Vacuolar transporter chaperone 1 (Negative regulator of CDC42 protein 1) (Phosphate metabolism protein 4)
[C7orf31] Uncharacterized protein C7orf31
[Cdyl] Chromodomain Y-like protein (CDY-like) (Crotonyl-CoA hydratase) (EC 4.2.1.-) (Putative histone acetyltransferase Cdyl) (EC 2.3.1.48)
[CTDNEP1 DULLARD] CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard)

Bibliography :
[32442250] Molecular plant responses to combined abiotic stresses put a spotlight on unknown and abundant genes.
[32440000] Dual roles of the sterol recognition region in Hedgehog protein modification.
[32438116] Classification and functional analyses of putative virulence factors of Mycobacterium tuberculosis: A combined sequence and structure based study.
[32437848] Multi-feature fusion for deep learning to predict plant lncRNA-protein interaction.
[32433612] TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
[32432970] Roles of Mso1 and the SM protein Sec1 in efficient vesicle fusion during fission yeast cytokinesis.
[32430468] Coevolution of Eukaryote-like Vps4 and ESCRT-III Subunits in the Asgard Archaea.
[32430407] Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin Resistance.
[32426863] The actin cytoskeletal network plays a role in yeast prion transmission and contributes to prion stability.
[32423862] Identification and functional characterization of ribosomal protein S23 as a new member of antimicrobial protein.