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Vimentin-4

 VIM4_XENLA              Reviewed;         463 AA.
P24790;
01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
01-MAR-1992, sequence version 1.
08-MAY-2019, entry version 81.
RecName: Full=Vimentin-4;
Name=vim4;
Xenopus laevis (African clawed frog).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Xenopus.
NCBI_TaxID=8355;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2806127;
Herrmann H., Fouquet B., Franke W.W.;
"Expression of intermediate filament proteins during development of
Xenopus laevis. I. cDNA clones encoding different forms of vimentin.";
Development 105:279-298(1989).
[2]
NUCLEOTIDE SEQUENCE [MRNA] OF 331-404.
PubMed=3224553;
Sharpe C.R.;
"Developmental expression of a neurofilament-M and two vimentin-like
genes in Xenopus laevis.";
Development 103:269-277(1988).
-!- FUNCTION: Vimentins are class-III intermediate filaments found in
various non-epithelial cells, especially mesenchymal cells.
Vimentin is attached to the nucleus, endoplasmic reticulum, and
mitochondria, either laterally or terminally.
-!- SUBUNIT: Homopolymer.
-!- PTM: One of the most prominent phosphoproteins in various cells of
mesenchymal origin. Phosphorylation is enhanced during cell
division, at which time vimentin filaments are significantly
reorganized.
-!- SIMILARITY: Belongs to the intermediate filament family.
{ECO:0000255|PROSITE-ProRule:PRU01188}.
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EMBL; X16844; CAA34742.1; -; mRNA.
PIR; B43549; B43549.
SMR; P24790; -.
MaxQB; P24790; -.
PRIDE; P24790; -.
GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
InterPro; IPR018039; IF_conserved.
InterPro; IPR039008; IF_rod_dom.
InterPro; IPR006821; Intermed_filament_DNA-bd.
InterPro; IPR027699; Vimentin.
PANTHER; PTHR45652:SF5; PTHR45652:SF5; 1.
Pfam; PF00038; Filament; 1.
Pfam; PF04732; Filament_head; 1.
SMART; SM01391; Filament; 1.
PROSITE; PS00226; IF_ROD_1; 1.
PROSITE; PS51842; IF_ROD_2; 1.
2: Evidence at transcript level;
Coiled coil; Intermediate filament.
CHAIN 1 463 Vimentin-4.
/FTId=PRO_0000063763.
DOMAIN 97 405 IF rod. {ECO:0000255|PROSITE-
ProRule:PRU01188}.
REGION 1 89 Head.
REGION 90 125 Coil 1A.
REGION 126 147 Linker 1.
REGION 148 239 Coil 1B.
REGION 240 262 Linker 12.
REGION 263 401 Coil 2.
REGION 402 463 Tail.
SITE 345 345 Stutter. {ECO:0000255}.
SEQUENCE 463 AA; 53497 MW; 15A1CD9547C99AFA CRC64;
MATTKSSYRR IFGGNPRSSS SGSRYVTSSS RYSLGSSMRP GTSSSRMVYS TSASPAVFKS
SSVRLRSSLP PARMADSVDF TLADAVNLEF KANRTNEKAE MIELNDRFAN FIDKVRFLEQ
QNKILVAELE QLKGKGTSRI GDLYEEEMRE IRRQLDQAIN EKARVEVDRD NLGDDLQRLR
EKLQDEMIQR EEAEGNLQSF RQDVDNASLA RIDLERKVES LQEEIVFLKK LHDEEIRELQ
LQIQESHIQV DMDVSKPDLT AALRDVRQQY ENVASKNLAD AEDWYKSKFA DLSEAANRNN
EALRQAKQDT NDYRRQIQTL TCEIDAMKGS NESYERQMRE MEENFALEAA NYQDTIQRLQ
EEIQNMKEEM SRHLREYQDL LNVKMALDIE IATYRKLLEG EESRITIPVH SFSTMSLRET
NLDSHPVDTH SKRTLLIKTV ETRDGQVINE SSQHHDDLDL DLE


Related products :

Catalog number Product name Quantity
orb22924 Vimentin antibody Monoclonal Mouse Anti Human Vimentin FITC 500
orb22923 Vimentin antibody Monoclonal Mouse Anti Human Vimentin Biotinylated 500
Mab-607041 Monoclonal Antibodies: Vimentin; Specificity: Vimentin ; Application: Elisa 0.1ml
orb22922 Vimentin antibody Monoclonal Mouse Anti Human Vimentin 500
ant-246 Mouse Anti Human Vimentin Biotinylated Vimentin Biotin 1mg
ant-246 Mouse Anti Human Vimentin Biotinylated Vimentin Biotin 500
ABP-FP-WVIM Alleleustrious pWasabi-Vimentin fusion vector Vimentin 5 ug
ABP-FP-TVIM Alleleustrious pmTFP1-Vimentin fusion vector Vimentin 5 ug
MA1102 Monoclonal Antibodies: Vimentin; reactive species: Human, rat.; Clone: VMT-24; Isotype: IgG1; Specificity: Vimentin 100?g
3634BP-50 Vimentin Blocking Peptide target: Vimentin 50 μg
18-271-81041 Vimentin - Chicken Anti Vimentin Polyclonal 0.1 mg
MAB - 606020118 Monoclonal Antibodies: Vimentin; reactive species: human; Clone: 9E7E7, 5G3F10,5G3F10E5; Isotype: IgG1; Specificity: Vimentin 0.1ml
L5-254-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
A4-460-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
A4-460-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
1C-460-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
1C-460-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
1C-254-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
1C-254-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
11-254-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
11-254-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
L5-254-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
11-460-C025 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.025 mg
11-460-C100 Mouse Monoclonal to Vimentin Antigen Vimentin Isotype IgM Antigen Vimentin Isotype IgM 0.1 mg
ant-245 Mouse Anti Human Vimentin Vimentin 500

Kits Elisa; taq POLYMERASE

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Pathways :
WP104: Alanine and aspartate metabolism
WP106: Alanine and aspartate metabolism
WP1126: Tryptophan metabolism
WP1329: Alpha6-Beta4 Integrin Signaling Pathway
WP1348: Androgen Receptor Signaling Pathway
WP1381: G13 Signaling Pathway
WP1530: miRNA regulation of DNA Damage Response
WP1545: miRNAs involved in DDR
WP2085: miRNAs involved in DDR
WP2087: miRNA regulation of DNA Damage Response
WP2316: PPAR signaling pathway
WP2347: vitamin B5 (pantothenate) and CoA biosynthesis Pathway
WP2353: vitamin B9 (folate) biosynthesis pathway
WP240: Alanine and aspartate metabolism
WP270: Tryptophan metabolism
WP434: TCA Cycle
WP465: Tryptophan metabolism
WP623: Oxidative phosphorylation
WP673: ErbB signaling pathway
WP79: Tryptophan metabolism

Related Genes :
[Ctsg] Cathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP)
[VIM] Vimentin
[Vim] Vimentin
[Vim] Vimentin
[VIM] Vimentin
[VIM] Vimentin
[VIM QtrA-12155] Vimentin
[NCKIPSD AF3P21 SPIN90] NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)
[VIM] Vimentin
[VIM] Vimentin
[VIM] Vimentin (Fragment)
[VIM] Vimentin
[] Genome polyprotein [Cleaved into: Core protein p21 (Capsid protein C) (p21); Core protein p19; Envelope glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2 (NS1) (gp68) (gp70); p7; Protease NS2-3 (p23) (EC 3.4.22.-); Serine protease NS3 (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Hepacivirin) (NS3P) (p70); Non-structural protein 4A (NS4A) (p8); Non-structural protein 4B (NS4B) (p27); Non-structural protein 5A (NS5A) (p56); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5B) (p68)]
[] Genome polyprotein [Cleaved into: Core protein p21 (Capsid protein C) (p21); Core protein p19; Envelope glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2 (NS1) (gp68) (gp70); p7; Protease NS2-3 (p23) (EC 3.4.22.-); Serine protease NS3 (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Hepacivirin) (NS3P) (p70); Non-structural protein 4A (NS4A) (p8); Non-structural protein 4B (NS4B) (p27); Non-structural protein 5A (NS5A) (p56); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5B) (p68)]
[VIM] Vimentin
[VIM] Vimentin (Fragment)
[EGM_17839] Vimentin
[vim4] Vimentin-4
[VIM] Vimentin
[Vim rCG_55877] Vimentin (Vimentin, isoform CRA_b)
[vim] Vimentin
[] Genome polyprotein [Cleaved into: Core protein p21 (Capsid protein C) (p21); Core protein p19; Envelope glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2 (NS1) (gp68) (gp70); p7; Protease NS2-3 (p23) (EC 3.4.22.-); Serine protease NS3 (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Hepacivirin) (NS3P) (p70); Non-structural protein 4A (NS4A) (p8); Non-structural protein 4B (NS4B) (p27); Non-structural protein 5A (NS5A) (p56); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5B) (p68)]
[vim1; vim2] Vimentin-1/2
[VIM] Vimentin
[VIM] Vimentin
[VIM CK820_G0041162] VIM isoform 1 (VIM isoform 2) (VIM isoform 5) (Vimentin)
[VIM] Vimentin
[VIM] Vimentin
[VIM] Vimentin
[Ftcd] Formimidoyltransferase-cyclodeaminase (58 kDa microtubule-binding protein) (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)]

Bibliography :
[26131016] Ougan (Citrus reticulata cv. Suavissima) flavedo extract suppresses cancer motility by interfering with epithelial-to-mesenchymal transition in SKOV3 cells.
[24766278] 'Neuroendocrine' middle ear adenomas: consistent expression of the transcription factor ISL1 further supports their neuroendocrine derivation.
[23097005] Histopathological, immunohistochemical and molecular spectrum of myoepithelial tumours of soft tissues.
[20403750] Differential protein expression in alligator leukocytes in response to bacterial lipopolysaccharide injection.
[20109354] Clinicopathologic analysis of 4 cases of primary renal synovial sarcoma.
[19781188] [Clinicopathologic analysis of mixed epithelial and stromal tumor of kidney and adult cystic nephroma].
[19320792] Myxoid atypical fibroxanthoma: a previously undescribed variant.
[19212771] Atypical teratoid/rhabdoid tumor of the central nervous system: clinicopathologic and immunohistochemical features of four cases.
[19124450] Clinicopathologic analysis of 4 perivascular epithelioid cell tumors (PEComas) of the gastrointestinal tract.
[18774495] Synovial sarcoma of the kidney.