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Index / Chondr / IMMsII _ Immunization grade mouse type II collagen /Product Detail : 20061 IMMsII _ Immunization grade mouse type II collagen
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IMMsII _ Immunization grade mouse type II collagen

 Price: 232   EUR
263   USD
180   GBP

Product name : IMMsII _ Immunization grade mouse type II collagen

Catalog number : 20061

Quantity: 1 mg lyophilized

Availability: Yes

Supplier name : Chondr

Data sheet Data sheet : Ask more or other datasheet now !

About this Product :

IMMsII _ Immunization grade mouse type II collagen mus musculus murine IMMsII _ Immunization grade mouse type II collagen detects proteins from variouse species most likely human.

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DESCRIPTION: Highly purified type II collagen (treated with 3M guanidine, DEAE-cellulose and Na2HPO4)
APPLICATION: Can be used for various purposes, such as a standard for collagen analysis by SDS-gel, substrate for MMP-1, MMP-8 and MMP-13, and as an antigen for immunizing animals for the induction of
collagen-induced arthritis (CIA) in certain species and strains of experimental animals.
FORM: Lyophilized powder
SOURCE: Mouse sternal cartilage
PURITY: >99% by SDS-PAGE, free of pepsin and proteoglycans
SOLUBILITY: Soluble in acidic buffer (maximum 4 mg/mL), but difficult to dissolve in neutral buffer. In order to dissolve this product in a neutral buffer, use 0.01M or 0.05M acetic acid to dissolve the collagen at 1-4 mg/mL and then add this collagen solution to a desired neutral buffer such as 2-10X Tris-NaCl (the final concentration of NaCl: 0.15-0.2M) or dialyze against 1X neutral buffer at 4°C.
Note 1: To avoid fibril formation under neutral conditions, keep solution on ice.
Note 2: The physicochemical property of type II collagen differs from type I collagen, and type II collagen
dissolved in a neutral buffer does not form stable gel with incubation at 37°C. In order to prepare
a type II collagen gel, additional components such as type I collagen or other substances might
be required.
STABILITY: 2 years

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