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Index / Bioquant / Bilirubin, Direct & Total, 4 x 120 ml /Product Detail : BQ007C-CR Bilirubin, Direct & Total, 4 x 120 ml
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  Price : 315   EUR
358   USD
244   GBP
1325   Zloty
42226   JPY
2433   NOK
2607   SEK
356   CHF

Product name : Bilirubin, Direct & Total, 4 x 120 ml

Catalog number : BQ007C-CR

Quantity: 480 Tests / Kit

Availability: Yes

Supplier name : Bioquant

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More Details about

Quantity 480 Tests
Sample Type Serum
Description
For the quantitative determination of direct and total bilirubin in human serum. Bilirubin is a metabolite of the heme portion of heme proteins, mainly hemoglobin. Normally, bilirubin is excreted into the intestine and bile from the liver. The site of the catabolism of hemoglobin is the reticuloendothelial system (RES). Bilirubin is then released into the bloodstream where it binds tightly to albumin and is transported to the liver. Upon uptake by the liver, bilirubin is conjugated with glucuronic acid to form bilirubin mono and diglucuronide, which are water-soluble metabolites. The metabolites will react with aqueous diazo reagent and are commonly referred to as “direct bilirubin”. Elevation of total serum bilirubin may occur due to (1) excessive hemolysis or destruction of the red blood cells (e.g. hemolytic disease of the newborn), (2) liver diseases (e.g. hepatitis and cirrhosis), (3) obstruction of the biliary tract (e.g.. gallstones). There is information in the literature indicating elevated levels of direct bilirubin in patients with liver or biliary tract disease, even though total bilirubin levels are normal. Therefore, the greatest diagnostic value of direct bilirubin assays stem from their ability to indicate occult liver disease.
Species Human
Info NA

 

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Related products : Bilirubin, Direct & Total, 4 x 120 ml


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Pathways :
WP1003: Ovarian Infertility Genes
WP1072: GPCRs, Class A Rhodopsin-like
WP112: Principle Pathways of Carbon Metabolism
WP1120: Ovarian Infertility Genes
WP1152: Mismatch repair
WP1188: GPCRs, Class A Rhodopsin-like
WP1204: Mismatch repair
WP1233: Mismatch repair
WP1257: Mismatch repair
WP1267: Senescence and Autophagy
WP1295: Mismatch repair
WP1305: Senescence and Autophagy
WP1340: Ovarian Infertility Genes
WP1361: Mismatch repair
WP1449: Regulation of toll-like receptor signaling pathway
WP1471: TOR signaling
WP1544: MicroRNAs in cardiomyocyte hypertrophy
WP1575: TOR signaling
WP2002: Epithelium TarBase
WP2003: Leukocyte TarBase
WP2004: Lymphocyte TarBase
WP2005: Muscle cell TarBase
WP2197: Endothelin
WP2291: Deregulation of Rab and Rab Effector Genes in Bladder Cancer
WP258: TGF-beta Receptor Signaling Pathway

Related Genes :
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[UGT1A1 GNT1 UGT1] UDP-glucuronosyltransferase 1-1 (UDPGT 1-1) (UGT1*1) (UGT1-01) (UGT1.1) (EC 2.4.1.17) (Bilirubin-specific UDPGT isozyme 1) (hUG-BR1) (UDP-glucuronosyltransferase 1-A) (UGT-1A) (UGT1A) (UDP-glucuronosyltransferase 1A1)
[MCOLN1 ML4 MSTP080] Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1)
[] Beta-galactoside-specific lectin 4 (Beta-galactoside-specific lectin IV) [Cleaved into: Beta-galactoside-specific lectin 4 chain A (EC 3.2.2.22) (Beta-galactoside-specific lectin IV chain A) (ML-4 A) (ML-IV A) (rRNA N-glycosidase); Beta-galactoside-specific lectin 4 chain B (Beta-galactoside-specific lectin IV chain B) (ML-4B) (ML-IV B)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[] Beta-galactoside-specific lectin 3 (Beta-galactoside-specific lectin II) (Beta-galactoside-specific lectin III) [Cleaved into: Beta-galactoside-specific lectin 3 chain A isoform 1 (EC 3.2.2.22) (Beta-galactoside-specific lectin III chain A isoform 1) (Lectin chain A isoform 2) (ML-3 A) (ML-III A) (rRNA N-glycosidase); Beta-galactoside-specific lectin 3 chain B (Beta-galactoside-specific lectin III chain B) (ML-3 B) (ML-III B)]
[UGT1A4 GNT1 UGT1] UDP-glucuronosyltransferase 1-4 (UDPGT 1-4) (UGT1*4) (UGT1-04) (UGT1.4) (EC 2.4.1.17) (Bilirubin-specific UDPGT isozyme 2) (hUG-BR2) (UDP-glucuronosyltransferase 1-D) (UGT-1D) (UGT1D) (UDP-glucuronosyltransferase 1A4)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[dosP dos pdeO yddU b1489 JW1484] Oxygen sensor protein DosP (EC 3.1.4.52) (Direct oxygen-sensing phosphodiesterase) (Direct oxygen sensor protein) (Ec DOS) (Heme-regulated cyclic di-GMP phosphodiesterase)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]

Bibliography :
[30905463] Glucuronidated bilirubin: Significantly increased in hepatic encephalopathy.
[30903555] Vitamin B combination reduces fluconazole toxicity in Wistar rats.
[30896413] Effects of cyclic parenteral nutrition on parenteral nutrition-associated cholestasis in newborns.
[30892407] THE CORRELATION OF NECK CIRCUMFERENCE AND INSULIN RESISTANCE IN NAFLD PATIENTS.
[30881426] Geriatric urinary tract infections: The value of laboratory parameters in estimating the need for bacteremia and Intensive Care Unit.
[30879747] Noninvasive assessment of liver fibrosis in pediatric intestinal failure patients using liver stiffness measurement by Vibration-Controlled Transient Elastography.
[30879557] Prevalence and Impact of Reformed and De Novo Anti-HLA Donor-Specific Antibodies in Liver Transplantation.
[30874733] Bile modulates secretion of incretins and insulin: a study on human extrahepatic cholestasis.
[30865314] Fatal acute hemolytic transfusion reaction due to anti-B from a platelet apheresis unit stored in platelet additive solution.
[30860886] Bilirubin Correlation May Preclude MRCP in Acute Cholecystitis Patients With Normal Common Bile Duct Diameter.