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Index / Biovis / Caspase_1 Inhibitor Z_YVAD_FMK 100 ul /Product Detail : 1012-100 Caspase_1 Inhibitor Z_YVAD_FMK 100 ul
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#1012-100 Caspase_1 Inhibitor Z_YVAD_FMK 100 ul

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  Price : 188   EUR
213   USD
146   GBP
790   Zloty
25192   JPY
1452   NOK
1555   SEK
212   CHF

Product name : Caspase_1 Inhibitor Z_YVAD_FMK 100 ul

Catalog number : 1012-100

Quantity: 100 ul

Availability: Yes

Supplier name : Biovis

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More Details about

STORAGE CONDITIONS: Store at – 20°C.
SHELF LIFE: 1 year under proper storage conditions
MOLECULAR WEIGHT: 630.7
SEQUENCE: Z-Tyr-Val-Ala-Asp(OMe)-FMK (FMK, fluoromethyl ketone)
PURITY: >99% by HPLC analysis



DESCRIPTION:
A synthetic peptide that irreversibly inhibits ICE (interleukin-1β converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1.
The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).


RECOMMENDED USAGE:
We recommend using 1000-5000X dilutions for inhibiting caspase-1 activity in Jurkat cell culture (e.g., Add 1 μl to 1-5 ml of culture medium). The optimal doses may vary for different cells and culture conditions.

 

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