Product name : Caspase_1 Inhibitor Z_YVAD_FMK 100 ul
Catalog number : 1012-100
Quantity: 100 ul
Supplier name : Biovis
Data sheet : Ask more or other datasheet now !
STORAGE CONDITIONS: Store at – 20°C.
SHELF LIFE: 1 year under proper storage conditions
MOLECULAR WEIGHT: 630.7
SEQUENCE: Z-Tyr-Val-Ala-Asp(OMe)-FMK (FMK, fluoromethyl ketone)
PURITY: >99% by HPLC analysis
A synthetic peptide that irreversibly inhibits ICE (interleukin-1β converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1.
The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
We recommend using 1000-5000X dilutions for inhibiting caspase-1 activity in Jurkat cell culture (e.g., Add 1 μl to 1-5 ml of culture medium). The optimal doses may vary for different cells and culture conditions.
Apoptosis Detection Kits & Reagents
Cell Fractionation System
Cell Proliferation & Senescence
Cell Damage & Repair
Adipocyte & Lipid Transfer
Molecular Biology & Reporter Assays
Growth Factors and Cytokines
Monoclonal and Polyclonal Antibodies
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