Product name : Active Human Caspase_10_b100 units
Catalog number : 1090B-100
Quantity: 100 units
Supplier name : Biovis
Data sheet : Ask more or other datasheet now !
Source: E. Coli.
Appearance: Lyophilized powder
Physical Form Description: Lyophilized powder
Molecular Weight: two large (18 kDa) and two small (11 kDa) subunits in a heterotetramer form.
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: > 15000 units/mg
Reconstitution Instructions: Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Storage Temp.: -70°C
Shipping: gel pack
Background Information: Caspase-10b (also known as FLICE 2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-10 also exists in cells as an inactive proenzyme. During apoptosis procaspase-10 is processed at aspartate residues to form active caspase-10 which consists of two large (18 kDa) and two small (11 kDa) subunits in a heterotetramer form. The recombinant active human caspase-10/b was expressed in E. coli. The active caspase-10 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-IETD-pNA (Cat. #1063-200) or Ac-IETD-AFC (1062-200).
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.
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