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Index / Biovis / Cerulenin50 mg /Product Detail : 1579-50 Cerulenin50 mg
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#1579-50 Cerulenin50 mg

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  Price : 856   EUR
971   USD
664   GBP
3595   Zloty
114511   JPY
6600   NOK
7072   SEK
968   CHF

Product name : Cerulenin50 mg

Catalog number : 1579-50

Quantity: 50 mg

Availability: Yes

Supplier name : Biovis

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More Details about

MOLECULAR WEIGHT: 223.3
PURITY: >98%
APPEARANCE: White to off-white powder
SOLUBILITY: Soluble in DMSO (20mg/ml), methanol or 100% ethanol (20mg/ml); slightly soluble in water.
STORAGE CONDITIONS: Store at -20°C; Protect from light.
BACKGROUND: Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or downstream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).
CAUTION: Do not ingest, swallow, or inhale. Do not get in eyes or on skin. Care should be taken to prevent contact through all routes of exposure.


FOR RESEARCH USE ONLY! Not to be used in humans.

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Pathways :
WP1013: Triacylglyceride Synthesis
WP1047: TNF-alpha NF-kB Signaling Pathway
WP1050: Oxidative Stress
WP1124: metapathway biotransformation
WP1166: Oxidative Stress
WP1251: metapathway biotransformation
WP1286: metapathway biotransformation
WP1372: Oxidative Stress
WP1502: Mitochondrial biogenesis
WP173: Oxidative Stress
WP212: Triacylglyceride Synthesis
WP2141: serotonin and anxiety
WP2298: NFE2L2
WP2364: NFE2L2
WP2370: NFE2L2
WP2376: NFE2L2
WP279: Triacylglyceride Synthesis
WP310: mRNA processing
WP375: Wnt Signaling Pathway NetPath
WP408: Oxidative Stress
WP412: Oxidative Stress
WP65: Insulin Signaling
WP702: metapathway biotransformation
WP889: metapathway biotransformation
WP932: Oxidative Stress

Related Genes :
[obgE cgtA obg yhbZ b3183 JW3150] GTPase ObgE/CgtA (EC 3.6.5.-) (GTP-binding protein Obg)
[rnr vacB yjeC b4179 JW5741] Ribonuclease R (RNase R) (EC 3.1.13.1) (Protein VacB)
[aphA napA yjbP b4055 JW4015] Class B acid phosphatase (CBAP) (EC 3.1.3.2)
[mgtA corB mgt b4242 JW4201] Magnesium-transporting ATPase, P-type 1 (EC 7.2.2.14) (Mg(2+) transport ATPase, P-type 1)
[ulaD sgaH yjfV b4196 JW4154] 3-keto-L-gulonate-6-phosphate decarboxylase UlaD (EC 4.1.1.85) (3-dehydro-L-gulonate-6-phosphate decarboxylase) (KGPDC) (L-ascorbate utilization protein D)
[dosC dgcO yddV b1490 JW5241] Diguanylate cyclase DosC (DGC) (EC 2.7.7.65) (Direct oxygen-sensing cyclase)
[ygbT cas1 b2755 JW2725] CRISPR-associated endonuclease Cas1 (EC 3.1.-.-)
[rhmA yfaU b2245 JW2239] 2-keto-3-deoxy-L-rhamnonate aldolase (KDR aldolase) (EC 4.1.2.53) (2-dehydro-3-deoxyrhamnonate aldolase) (2-keto-3-deoxy acid sugar aldolase)
[dinB dinP b0231 JW0221] DNA polymerase IV (Pol IV) (EC 2.7.7.7) (Translesion synthesis polymerase IV) (TSL polymerase IV)
[cpxA ecfB eup ssd b3911 JW3882] Sensor histidine kinase CpxA (EC 2.7.13.3)
[phoQ b1129 JW1115] Sensor protein PhoQ (EC 2.7.13.3) (EC 3.1.3.-) (Sensor histidine protein kinase/phosphatase PhoQ)
[hipA b1507 JW1500] Serine/threonine-protein kinase toxin HipA (Ser/Thr-protein kinase HipA) (EC 2.7.11.1) (Toxin HipA)
[rlmE ftsJ mrsF rrmJ b3179 JW3146] Ribosomal RNA large subunit methyltransferase E (EC 2.1.1.166) (23S rRNA Um2552 methyltransferase) (Cell division protein FtsJ) (rRNA (uridine-2'-O-)-methyltransferase)
[pyrDA llmg_0952] Dihydroorotate dehydrogenase A (fumarate) (DHOD A) (DHODase A) (DHOdehase A) (EC 1.3.98.1)
[cydX ybgT b4515 JW0724] Cytochrome bd-I ubiquinol oxidase subunit X (EC 7.1.1.7) (Cytochrome bd-I oxidase subunit X) (Cytochrome d ubiquinol oxidase subunit X)
[rsgA engC yjeQ b4161 JW4122] Small ribosomal subunit biogenesis GTPase RsgA (EC 3.6.1.-)
[clcA eriC yadQ b0155 JW5012] H(+)/Cl(-) exchange transporter ClcA (ClC-ec1)
[ygcB cas3 b2761 JW2731] CRISPR-associated endonuclease/helicase Cas3 (EC 3.1.-.-) (EC 3.6.4.-)
[rppH nudH ygdP b2830 JW2798] RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase) (Ap5A pyrophosphatase)
[nudC yjaD b3996 JW5548] NADH pyrophosphatase (EC 3.6.1.22)
[dgcN yfiN b2604 JW2585] Diguanylate cyclase DgcN (DGC) (EC 2.7.7.65)
[lysU b4129 JW4090] Lysine--tRNA ligase, heat inducible (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
[pdeL yahA b0315 JW0307] Cyclic di-GMP phosphodiesterase PdeL (EC 3.1.4.52)
[pgpA yajN b0418 JW0408] Phosphatidylglycerophosphatase A (EC 3.1.3.27) (Phosphatidylglycerolphosphate phosphatase A) (PGP phosphatase A)
[wecA rfe b3784 JW3758] Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) (UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase) (Undecaprenyl-phosphate GlcNAc-1-phosphate transferase)
[dosP dos pdeO yddU b1489 JW1484] Oxygen sensor protein DosP (EC 3.1.4.52) (Direct oxygen-sensing phosphodiesterase) (Direct oxygen sensor protein) (Ec DOS) (Heme-regulated cyclic di-GMP phosphodiesterase)
[aldB yiaX b3588 JW3561] Aldehyde dehydrogenase B (EC 1.2.1.-)
[gmhB yaeD b0200 JW0196] D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase (EC 3.1.3.82) (D,D-heptose 1,7-bisphosphate phosphatase) (HBP phosphatase)
[glpF b3927 JW3898] Glycerol uptake facilitator protein (Aquaglyceroporin)
[mqsR ygiU b3022 JW2990] mRNA interferase toxin MqsR (EC 3.1.-.-) (Endoribonuclease MqsR) (Motility quorum-sensing regulator MqsR) (Toxin MqsR)

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