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Index / Biovis / Proteinase Inhibitor 9 (PI9) pAb100 ug /Product Detail : 3544R-100 Proteinase Inhibitor 9 (PI9) pAb100 ug
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#3544R-100

Proteinase Inhibitor 9 (PI9) pAb100 ug

 Price: 314   EUR
357   USD
244   GBP

Product name : Proteinase Inhibitor 9 (PI9) pAb100 ug

Catalog number : 3544R-100

Quantity: 100 ug

Availability: Yes

Supplier name : Biovis

Data sheet Data sheet : Ask more or other datasheet now !

About this Product :

Proteinase Inhibitor 9 (PI9) pAb100 ug polyclonal antibodies polyclonal antobodies can be directed against a recombinant proteine, the natural protein or an epitope. The epitope generated polyclonals are virtual monoclonals. You can request the immogen of Proteinase Inhibitor 9 (PI9) pAb100 ug at [email protected]
http://mybiofast.com/ver.php?search=polyclonal&submit=Search

More Details about

HOST: Rabbit


IMMUNOGEN: Synthetic peptide mapping to the N-terminus of human PI-9 (ID# BV-431)


SPECIES REACTIVITY: human


FORMULATION:
100 μg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.


STORAGE CONDITIONS:
Store at -20oC. For long term storage, aliquot and freeze at –70oC. Avoid repeated freeze/defrost cycles.


BACKGROUND:
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.


SPECIFICITY:
The antibody recognizes 42 kDa human PI-9. Reactivity to other species has not been tested.


APPLICATION:
The antibody can be used in Western blotting (1-4 μg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3544R-50) is available separately.


FOR RESEARCH USE ONLY! Not to be used on humans.

 

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