GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Index / Biovis / Caspase-10 Inhibitor AEVD-FMK ; Appearance Liquid /Product Detail : 1112-100 Caspase-10 Inhibitor AEVD-FMK ; Appearance Liquid
Related keywords:

#1112-100 Caspase-10 Inhibitor AEVD-FMK ; Appearance Liquid

Ask technical file .

  Price : 209   EUR
238   USD
162   GBP
880   Zloty
28055   JPY
1617   NOK
1732   SEK
237   CHF

Product name : Caspase-10 Inhibitor AEVD-FMK ; Appearance Liquid

Catalog number : 1112-100

Quantity: 100

Availability: Yes

Supplier name : Biovis

ask pdf gentaur products Data sheet : Ask more or other datasheet now !

More Details about

STORAGE CONDITIONS: Store at –20°C.
SHELF LIFE: 1 year under proper storage conditions
MOLECULAR WEIGHT: 610.63
SEQUENCE: Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK (FMK, fluoromethyl ketone)
PURITY: >95% by HPLC analysis.
PACKAGE CONTENTS: 100 μl (2 mM) Z-AEVD-FMK in DMSO


DESCRIPTION:
A synthetic peptide inhibitor that inhibits caspase-10 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies.
The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).


RECOMMENDED USAGE:
We recommend using 1000X dilutions for inhibiting caspase-10 and related caspase activity (e.g., Add 1 μl to 1 ml of culture medium). The optimal doses may vary for different cells and culture conditions. The inhibitor is designed as a methyl ester to facilitate cell permeability.

 

For Research Use Only! Not to be used in humans.

 

RELATED PRODUCTS:


Apoptosis Detection Kits & Reagents

  • Annexin V Kits & Bulk Reagents
  • Caspase Assay Kits & Reagents
  • Mitochondrial Apoptosis Kits & Reagents
  • Nuclear Apoptosis Kits & Reagents
  • Apoptosis Inducers and Set
  • Apoptosis siRNA Vectors

 

Cell Fractionation System

  • Mitochondria/Cytosol Fractionation Kit
  • Nuclear/Cytosol Fractionation Kit
  • Membrane Protein Extraction Kit
  • Cytosol/Particulate Rapid Separation Kit
  • Mammalian Cell Extraction Kit
  • FractionPREP Fractionation System

 

Cell Proliferation & Senescence

  • Quick Cell Proliferation Assay Kit
  • Senescence Detection Kit
  • High Throughput Apoptosis/Cell Viability Assay Kits
  • LDH-Cytotoxicity Assay Kit
  • Bioluminescence Cytotoxicity Assay Kit
  • Live/Dead Cell Staining Kit


Cell Damage & Repair

  • HDAC Fluorometric & Colorimetric Assays & Drug Discovery Kits
  • HAT Colorimetric Assay Kit & Reagents
  • DNA Damage Quantification Kit
  • Glutathione & Nitric Oxide Fluorometric & Colorimetric Assay Kits


Signal Transduction

  • cAMP & cGMP Assay Kits
  • Akt & JNK Activity Assay Kits
  • Beta-Secretase Activity Assay Kit


Adipocyte & Lipid Transfer

  • Recombinant Adiponectin, Survivin, & Leptin
  • CETP Activity Assay & Drug Discovery Kits
  • PLTP Activity Assay & Drug Discovery Kits
  • Total Cholesterol Quantification Kit


Molecular Biology & Reporter Assays

  • siRNA Vectors
  • Cloning Insert Quick Screening Kit
  • Mitochondrial & Genomic DNA Isolation Kits
  • 5 Minutes DNA Ligation Kit
  • 20 Minutes Gel Staining/Destaining Kit
  • β -Galactosidase Staining Kit & Luciferase Reporter Assay Kit


Growth Factors and Cytokines
Monoclonal and Polyclonal Antibodies

Contact us about this product :

Our team will respond you as soon as possible !

Email :
Skype :
Name :
Phone :
address :
Question, Comment :
arrow security gentaurPlease retype this code below :
Biovis \ Caspase_10_Inhibitor_AEVD_FMK_;_Appearance_Liquid \ 1112_100
Reload Image

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Related products : Caspase-10 Inhibitor AEVD-FMK ; Appearance Liquid


Gentaurpub

Pathways :
WP1033: ACE Inhibitor Pathway
WP1151: ACE Inhibitor Pathway
WP1965: VEGF-receptor Signal Transduction
WP2359: Parkin-Ubiquitin Proteasomal System pathway
WP396: ACE Inhibitor Pathway
WP468: ACE Inhibitor Pathway
WP554: ACE Inhibitor Pathway
WP557: ACE Inhibitor Pathway
WP801: ACE Inhibitor Pathway
WP88: Toll Like Receptor signaling
WP915: ACE Inhibitor Pathway

Related Genes :
[CASP14] Caspase-14 (CASP-14) (EC 3.4.22.-) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]
[CARD16 COP COP1] Caspase recruitment domain-containing protein 16 (Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme)
[CFLAR CASH CASP8AP1 CLARP MRIT] CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
[CASP9 MCH6] Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
[CASP8 MCH5] Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
[CASP1 IL1BC IL1BCE] Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
[Cflar Cash] CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
[csp-1 Y48E1B.13] Caspase A (EC 3.4.22.36) [Cleaved into: Caspase A subunit p16; Caspase A subunit p14]
[CASP10 MCH4] Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
[Casp1 Il1bc] Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
[RNF34] E3 ubiquitin-protein ligase RNF34 (EC 2.3.2.27) (Caspase regulator CARP1) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (RING finger protein 34) (RING finger protein RIFF) (RING-type E3 ubiquitin transferase RNF34)
[ced-3 C48D1.2] Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]
[Casp14] Caspase-14 (CASP-14) (EC 3.4.22.-) (Mini-ICE) (MICE) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]
[CASP2 ICH1 NEDD2] Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]
[Casp4 Casp11 Caspl Ich3] Caspase-4 (CASP-4) (EC 3.4.22.64) (Caspase-11) (CASP-11) (Protease ICH-3) [Cleaved into: Caspase-4 subunit p10; Caspase-4 subunit p20]
[csp-2 Y73B6BL.7] Putative inactive caspase B [Cleaved into: Putative inactive caspase B subunit p31; Putative inactive caspase B subunit p17; Putative inactive caspase subunit p14]
[Casp9 Mch6] Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
[CASP5 ICH3] Caspase-5 (CASP-5) (EC 3.4.22.58) (ICE(rel)-III) (Protease ICH-3) (Protease TY) [Cleaved into: Caspase-5 subunit p20; Caspase-5 subunit p10]
[Casp8] Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
[Dredd DCP2 CG7486] Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
[Casp8] Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
[Casp1 Il1bc Il1bce] Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
[CARD17 INCA] Caspase recruitment domain-containing protein 17 (Caspase-1 inhibitor INCA) (Inhibitory caspase recruitment domain protein)
[CARD18 ICEBERG UNQ5804/PRO19611] Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg)
[Dronc Nc CG8091] Caspase Dronc (EC 3.4.22.-) (NEDD2-like caspase) [Cleaved into: Caspase Nc subunit 1; Caspase Nc subunit 2]
[CASP3 CPP32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[CASP4 ICH2] Caspase-4 (CASP-4) (EC 3.4.22.57) (ICE and Ced-3 homolog 2) (ICH-2) (ICE(rel)-II) (Mih1) (Protease TX) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]
[Casp3 Cpp32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (IRP) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[Casp3 Cpp32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[CARD8 KIAA0955 NDPP1] Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (DACAR) (Tumor up-regulated CARD-containing antagonist of CASP9) (TUCAN)

Bibliography :
[21911414] Apoptosis induced by avian H5N1 virus in human monocyte-derived macrophages involves TRAIL-inducing caspase-10 activation.
[21288283] Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways.
[20162409] Magnolol induces apoptosis via activation of both mitochondrial and death receptor pathways in A375-S2 cells.
[20094800] The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells.
[17695501] Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7.
[15301743] Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway.
[15276646] Involvement of caspase-10 in advanced glycation end-product-induced apoptosis of bovine retinal pericytes in culture.
[15215653] Dracorhodin perchlorate induces apoptosis via activation of caspases and generation of reactive oxygen species.
[14761933] Identification of caspase-10 in human neutrophils and its role in spontaneous apoptosis.
[12646627] Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway.