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Index / Biovis / Fasudil, Monohydrochloride; Appearance White to off-white solid /Product Detail : 1787-10 Fasudil, Monohydrochloride; Appearance White to off-white solid
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#1787-10 Fasudil, Monohydrochloride; Appearance White to off-white solid

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  Price : 169   EUR
191   USD
131   GBP
710   Zloty
22616   JPY
1303   NOK
1396   SEK
191   CHF

Product name : Fasudil, Monohydrochloride; Appearance White to off-white solid

Catalog number : 1787-10

Quantity: 10 mg

Availability: Yes

Supplier name : Biovis

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Alternate Name/Synonyms: 1-(5-Isoquinolinesulfonyl)homopiperazine, Monohydrochloride Salt; HA-1077, Monohydrochloride; AT-877

Peptide sequence: N/A

Appearance: White to off-white solid

Formulation: Water (175 mg/ml) or DMSO (10 mg/ml)

CAS Number: 105628-07-7

Molecular Formula: C₁₄H₁₇N₃O₂S•HCl

Molecular Weight: 327.83

Purity: ≥99% by HPLC

Solubility: Water (175 mg/ml) or DMSO (10 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A cell-permeable Ca²⁺ antagonist and vasodilator. Inhibits protein kinase A (Ki = 1.6 µM), protein kinase G (Ki = 1.6 µM), myosin light chain kinase (Ki = 36 µM) and Rho kinase (ROCK; IC₅₀ = 10.7 µM. Fasudil also mobilizes adult neural stem cells in vivo.

Handling: Protect from air and moisture

 

USAGE: For Research Use Only! Not For Use in Humans.

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Related Genes :
[WOR1 EAP2 TOS9 CAALFM_C110150WA CaO19.12348 CaO19.4884] White-opaque regulator 1
[w CG2759] Protein white
[SHW1 At1g69935 T17F3] Protein SHORT HYPOCOTYL IN WHITE LIGHT 1
[ABCG1 ABC8 WHT1] ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)
[sgg gsk3 zw3 CG2621] Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)
[FKS1 CND1 CWH53 ETG1 GLS1 GSC1 PBR1 YLR342W L8300.6] 1,3-beta-glucan synthase component FKS1 (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (Calcineurin dependent protein 1) (Calcofluor white hypersensitivity protein 53) (Echinocandin target gene protein 1) (FK506 sensitivity protein 1) (Glucan synthase of cerevisiae protein 1) (Papulacandin B resistance protein 1)
[Abcg1 Abc8 Wht1] ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)
[SFSWAP SFRS8 SWAP] Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)
[PMEL MMP115 PMEL17 SILV] Melanocyte protein PMEL (115 kDa melanosomal matrix protein) (Melanocyte protein Pmel 17) (Premelanosome protein) (Silver locus protein homolog)
[RCN1 WBC5 LOC_Os03g17350 Os03g0281900 OsJ_10379] ABC transporter G family member 5 (ABC transporter ABCG.5) (OsABCG5) (Protein REDUCED CULM NUMBER 1) (White-brown complex homolog protein 5) (OsWBC5)
[ABCG11 COF1 DSO PEL1 WBC11 At1g17840 F2H15.7] ABC transporter G family member 11 (ABC transporter ABCG.11) (AtABCG11) (Protein CUTICULAR DEFECT AND ORGAN FUSION 1) (Protein DESPERADO) (Protein PERMEABLE LEAVES 1) (White-brown complex homolog protein 11) (AtWBC11)
[CA2] Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II)
[FBP1 FBP] Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase)
[PPP1CA PPP1A] Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
[] Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form]
[ABCG12 CER5 D3 WBC12 At1g51500 F5D21.6] ABC transporter G family member 12 (ABC transporter ABCG.12) (AtABCG12) (Protein ECERIFERUM 5) (White-brown complex homolog protein 12) (AtWBC12)
[ABCG4 WHITE2] ATP-binding cassette sub-family G member 4
[rep 1a-1b] Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); 3C-like serine proteinase (3CLSP) (EC 3.4.21.-) (M-PRO) (nsp3) (p27); Non-structural protein 4 (nsp4); Non-structural protein 5 (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (nsp9); Helicase (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (nsp10); Exoribonuclease (ExoN) (EC 3.1.13.-) (nsp11); Non-structural protein 12 (nsp12); Uridylate-specific endoribonuclease (EC 3.1.-.-) (NendoU) (nsp13); Putative 2'-O-methyl transferase (EC 2.1.1.-) (nsp14)]
[CWH43 YCR017C YCR17C] Protein CWH43 (Calcofluor white hypersensitive protein)
[egh l(1)3Ae zw4 CG9659] Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)
[ADR2 WRR4 At1g56510 F13N6.5] Disease resistance protein ADR2 (Protein ACTIVATED DISEASE RESISTANCE 2) (Protein WHITE RUST RESISTANCE 4)
[PPP1CB] Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
[LPL] Lipoprotein lipase (LPL) (EC 3.1.1.34)
[ACAN AGC1] Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP)
[TGFB3] Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-3 (TGF-beta-3)]
[INS] Insulin [Cleaved into: Insulin B chain; Insulin A chain]
[SHMT1] Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
[KCNJ2 IRK1] Inward rectifier potassium channel 2 (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2)
[FMO2] Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)
[INHBA] Inhibin beta A chain (Activin beta-A chain)

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