Product name : Human, Lipoprotein Lipase, E.coli , Rec. Prot.
Catalog number : RD172131100
Quantity: 0.1 mg
Supplier name : Biovend
Data sheet : Ask more or other datasheet now !
Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. When LPL is produced by macrophages in the vessel wall it has proatherogenic effects. The atherogenic effects of LPL have been attributed mainly to its ability to favor lipid accumulation within macrophages in the atherosclerotic lesion. LPL also promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
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