Product name : Human, Neuroglobin , Rec. Prot.
Catalog number : RD172043100
Quantity: 0.1 mg
Supplier name : Biovend
Data sheet : Ask more or other datasheet now !
Neuroglobin is a recently identified member of the globin superfamily. It is expressed in vertebrate brain and retina, Facilitating O(2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo. The neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide. On the other hand, it is enhanced by neuroglobin overexpression
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