Product name : Human, Retinol Binding Protein 4 , Rec. Prot.
Catalog number : RD172104100
Quantity: 0.1 mg
Supplier name : Biovend
Data sheet : Ask more or other datasheet now !
Retinol binding protein (RBP) 4 is the only specific transport protein for vitamin A in the circulation whose function is to deliver vitamin to target tissues. The expression of Glut4 is significantly impaired in adipocytes in cases of obesity and type 2 diabetes. Glucose transport via Glut4 is the rate-limiting step for glucose use by muscle and adipose tissue. Yang et al. noted that adipocyte-specific deletion of Gluts leads to notable elevation of RBP4 causing systemic insulin resistance, and that reduction of RBP4 improved insulin resistance. This identified a novel role of RBP4 in regulating insulin action. This is why it is regarded as an adipocyte-derived hormone. Thus, measurement of serum or plasma RBP4 is a useful mean for understanding metabolic disorders.
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