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Index / Biovend / Human, Retinol Binding Protein 4 , Rec. Prot. /Product Detail : RD172104100 Human, Retinol Binding Protein 4 , Rec. Prot.
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Human, Retinol Binding Protein 4 , Rec. Prot.

 Price: 429   EUR
486   USD
332   GBP

Product name : Human, Retinol Binding Protein 4 , Rec. Prot.

Catalog number : RD172104100

Quantity: 0.1 mg

Availability: Yes

Supplier name : Biovend

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Retinol binding protein (RBP) 4 is the only specific transport protein for vitamin A in the circulation whose function is to deliver vitamin to target tissues. The expression of Glut4 is significantly impaired in adipocytes in cases of obesity and type 2 diabetes. Glucose transport via Glut4 is the rate-limiting step for glucose use by muscle and adipose tissue. Yang et al. noted that adipocyte-specific deletion of Gluts leads to notable elevation of RBP4 causing systemic insulin resistance, and that reduction of RBP4 improved insulin resistance. This identified a novel role of RBP4 in regulating insulin action. This is why it is regarded as an adipocyte-derived hormone. Thus, measurement of serum or plasma RBP4 is a useful mean for understanding metabolic disorders.

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