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anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse
/Product Detail : LF-MA0220 anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse
Product name : anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse
Catalog number : LF-MA0220
Quantity: 100 ul
Supplier name : Abfron
Data sheet : Ask more or other datasheet now !
anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse imuno globulin 2 22% abundance in serum with lof affinityfor anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse
anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse http://biotech-map.com/aa_search/table_sample.html?q=monoclonal&filter=
anti-PP2A-α_β (20G6), Mouse monoclonal to PP2A-α_β, Isotype IgG2b, Host Mouse is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
Protein Phosphatase 2A (PP2A) is a ubiquitous and conserved Serine/Threonine phosphatase and accounts for a large fraction of phosphatase activity in eukaryotic cells. PP2A plays an important role in cell cycle regulation, cell growth control, development, egulation of various signal transduction pathways, and cell mobility. PP2A comprises A and B subunits which are regulatory and a catalytic C subunit. When the PP2A catalytic C subunit (36 kDa) associates with the regulatory A (65 kDa, PR65) and B subunits (PR55, PR56, PR72, PR93 etc), wide variety of heterotrimeric holoenzymes are produced with distinct functions and characteristics. The different association of the subunits give PP2A large regulatory flexibility and differential substrate specificity. The A subunit exists as two isoforms ( α and β ) as does the C subunit, whereas the B subunits fall into three families designated B, B' (also called B56), and B''. The A subunit is the scaffold required for the formation of the heterotrimeric complex and the binding of A subunit alters the enzymatic activity of the catalytic subunit, even if the B subunit is absent. Storage : Store for 1 year at –20°C from date of shipment Applications
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