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Index / Biovis / QVD_OPh Negative Control /Product Detail : 1171-5 QVD_OPh Negative Control
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#1171-5 QVD_OPh Negative Control

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  Price : 772   EUR
876   USD
599   GBP
3244   Zloty
103347   JPY
5956   NOK
6382   SEK
873   CHF

Product name : QVD_OPh Negative Control

Catalog number : 1171-5

Quantity: 5 mg

Availability: Yes

Supplier name : Biovis

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More Details about

STORAGE CONDITIONS: Store at –20°C.
Solubility: Soluble in DMSO
SHELF LIFE: 1 year under proper storage conditions
Molecular Weight: 527.19
Chemical Formula: C27H27F2N3O6
PURITY: >95% by HPLC analysis
APPEARANCE: Pure thin resin


DESCRIPTION:
A synthetic peptide that is cell permeable, nontoxic and used as a negative control to the caspase inhibitor Q-VD-OPH, the new generation of caspase inhibitor. It is stable in aqueous environment and exhibits several folds less inhibitory activity than the corresponding caspase Q-VD-OPH. It is the perfect choice for both in vitro and in vivo studies.


RECOMMENDED USAGE:
We recommend using 1-10 μM concentration for in vitro enzyme kinetics studies. For in vivo usage, quantity needs to be determined by researcher. 20 mg/Kg of body weight is a proper place to start.

 

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Pathways :
WP1078: G1 to S cell cycle control
WP1195: G1 to S cell cycle control
WP2357: Heterchronic control of molting
WP348: G1 to S cell cycle control
WP413: G1 to S cell cycle control
WP445: G1 to S cell cycle control
WP45: G1 to S cell cycle control
WP840: G1 to S cell cycle control
WP959: G1 to S cell cycle control

Related Genes :
[Pre C,C C core E PC pre-C pre-C/C PreC preC PreC/C preC/C precore-core HBVgp4] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[VPS2.1 CHMP2-1 SLP At2g06530 T12H3.8] Vacuolar protein sorting-associated protein 2 homolog 1 (AtVPS2-1) (Charged multivesicular body protein 2 homolog 1) (ESCRT-III complex subunit VPS2 homolog 1) (SNF7-like protein)
[oph] Oxidized polyvinyl alcohol hydrolase (OPH) (Oxidized PVA hydrolase) (EC 3.7.1.7) (Beta-diketone hydrolase)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[C c core preC HBVgp4] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[nef] Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
[nef] Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
[COI] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)
[PHO85 SSG3 YPL031C P7102.18A] Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
[CDK1 CDC2 CDC28A CDKN1 P34CDC2] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
[C PC PreC/C HBVgp4] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[S PreS1 preS1 preS1/S2/S preS2] Large envelope protein (L glycoprotein) (L-HBsAg) (LHB) (Large S protein) (Large surface protein) (Major surface antigen)
[AARE At4g14570 dl3325w] Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Oxidized protein hydrolase) (OPH)
[APEH D3F15S2 D3S48E DNF15S2] Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH)
[cdc2 cdk1 swo2 pi002 SPBC11B10.09] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)
[UME6 CAR80 CARGR1 NIM2 RIM16 YDR207C YD8142.04C] Transcriptional regulatory protein UME6 (Negative transcriptional regulator of IME2) (Regulator of inducer of meiosis protein 16) (Unscheduled meiotic gene expression protein 6)
[cdk1-a cdc2-a cdc2x1.1] Cyclin-dependent kinase 1-A (CDK1-A) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog 1) (Cell division control protein 2-A) (Cell division protein kinase 1-A) (p34 protein kinase 1)
[cdk1-b cdc2 cdc2x1.2] Cyclin-dependent kinase 1-B (CDK1-B) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog 2) (Cell division control protein 2-B) (Cell division protein kinase 1) (p34 protein kinase 2)
[CDC6 CDC18L] Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
[cdc10 SPBC336.12c] Start control protein cdc10
[GCN2 AAS1 YDR283C] eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (General control non-derepressible protein 2) (Serine/threonine-protein kinase GCN2)
[Cdk1 Cdc2 Cdc2a Cdkn1] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
[GCN4 AAS3 ARG9 YEL009C] General control protein GCN4 (Amino acid biosynthesis regulatory protein)
[CDC48 YDL126C] Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
[paiA BSU32150] Spermidine/spermine N(1)-acetyltransferase (SSAT) (Protease synthase and sporulation negative regulatory protein PAI 1) (Spermidine N(1)-acetyltransferase) (SAT) (EC 2.3.1.57)
[CDC28 CDK1 HSL5 SRM5 YBR160W YBR1211] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
[MEA EMB173 FIS1 MEDEA SDG5 SET5 At1g02580 T14P4.11] Histone-lysine N-methyltransferase MEDEA (EC 2.1.1.43) (Maternal embryogenesis control protein) (Protein EMBRYO DEFECTIVE 173) (Protein FERTILIZATION-INDEPENDENT SEED 1) (Protein SET DOMAIN GROUP 5)
[Cdk1 Cdc2 Cdc2a Cdkn1] Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
[phoU nmpA b3724 JW3702] Phosphate-specific transport system accessory protein PhoU (Pst system accessory protein PhoU) (Negative regulator of Pho regulon)
[nmrA AN8168] Nitrogen metabolite repression protein nmrA (Negative-acting nitrogen regulatory protein nmrA) (Nitrogen metabolite regulation protein)

Bibliography :
[24973240] Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis.