Product name : Thiazovivin
Catalog number : 1681-1
Quantity: 1 mg
Supplier name : Biovis
Data sheet : Ask more or other datasheet now !
CAS NUMBER: 1226056-71-8
APPEARANCE: Off-white solid
SOLUBILITY: DMSO (100 mM)
PURITY: >98% by HPLC
STORAGE: Store at -20°C. Protect from air and light
DESCRIPTION: Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. In combination with ALK5 inhibitor SB-431542 (Cat. No. 1674-1) and MEK inhibitor PD-0325901 (Cat. No. 1643-2), Thiazovivin promotes the transformation of fibroblasts into stem cells with a 200-fold efficiency.
HANDLING: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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| Generation of Urine Cell-Derived Non-integrative Human iPSCs and iNSCs: A Step-by-Step Optimized Protocol.|
| The ROCK inhibitor, thiazovivin, inhibits human corneal endothelial‑to‑mesenchymal transition/epithelial‑to‑mesenchymal transition and increases ionic transporter expression.|
| Holding of bovine blastocysts at suprazero temperatures using small molecules.|
| [Effect of a new ROCK inhibitor thiazovivin on the morphology and function of human corneal endothelial cells].|
| Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder.|
| Thiazovivin, a Rho kinase inhibitor, improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle.|
| GPR4 decreases B16F10 melanoma cell spreading and regulates focal adhesion dynamics through the G13/Rho signaling pathway.|
| Reprogramming of endometrial adult stromal cells in the presence of a ROCK inhibitor, thiazovivin, could obtain more efficient iPSCs.|
| Generation of induced pluripotent stem cells without genetic defects by small molecules.|
| Alternative cultures for human pluripotent stem cell production, maintenance, and genetic analysis.|