GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Index / Biovend / Hepatitis B Protein X Rec. Prot. /Product Detail : RD972038100 Hepatitis B Protein X Rec. Prot.
Related keywords:

#RD972038100

Hepatitis B Protein X Rec. Prot.

 Price: 460   EUR
522   USD
356   GBP

Product name : Hepatitis B Protein X Rec. Prot.

Catalog number : RD972038100

Quantity: 0.1 mg

Availability: Yes

Supplier name : Biovend

Data sheet Data sheet : Ask more or other datasheet now !

More Details about

 

Hepatitis B virus X protein (HBx) is a 17 kD transcriptional coactivator that plays a major role in the regulation of genes related to inflammation and cell survival. It regulates many transcription factors including nuclear factor kappa B (NF-kappaB). It also plays a key role in hepatocarcino­genesis. HBx facilitates the binding of cAMP response element binding protein (CREB) to its responsive element. HBx stabilizes the cellular coactivator ASC-2 through direct protein-protein interaction, affecting the regulation of genes, which are actively transcribed in liver cancer cells.

Moreover, HBx transactivates both JNK and MAPK signal transduction pathways in association with the mobilization of cytosolic Ca2+. In addition, HBx decreases the expression of PTEN a known tumor suppressor and a negative regulator of phosphatidyli­nositol 3'-kinase/AKT. HBx also decreased the expression of PTEN in HBx-transfected cells.

The etiology of hepatocellular carcinoma (HCC) is involved with hepatitis B virus (HBV) infection and HBx in particular plays a role in the development of HBV-related HCC. The persistence of HBx is important to the pathogenesis of early HCC. HBx expression in the liver during chronic HBV infection may be an important prognostic marker for the development of HCC.

Contact us about this product :

Our team will respond you as soon as possible !

Email :
Skype :
Name :
Phone :
address :
Question, Comment :
arrow security gentaurPlease retype this code below :
Biovend \ Hepatitis_B_Protein_X_Rec._Prot. \ RD972038100
Reload Image

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can