Product name : Osteoblast Specific Factor 2 Rec. Prot.
Catalog number : RD172045100
Quantity: 0.1 mg
Supplier name : Biovend
Data sheet : Ask more or other datasheet now !
Periostin is a disulfide linked 90 kDa, 811 amino acid protein. It was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts. It is involved in osteoblast recruitment, attachment and spreading. Additionally, it has been shown that periostin expression is significantly increased by both transforming growth factor beta-1(TGFbeta1) and bone morphogenetic protein (BMP-2).
OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin
Periostin mRNA is expressed in the developing mouse embryonic and fetal heart. It is localized to the endocardial cushions that ultimately divides the primitive heart tube into a four-chambered heart.
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