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Index / Biovis / Caspase-4 Antibody MonoclonalHost: Mouse D44 /Product Detail : 3328-100 Caspase-4 Antibody MonoclonalHost: Mouse D44
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#3328-100 Caspase-4 Antibody MonoclonalHost: Mouse D44

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  Price : 384   EUR
435   USD
297   GBP
1613   Zloty
51387   JPY
2961   NOK
3173   SEK
434   CHF

Product name : Caspase-4 Antibody MonoclonalHost: Mouse D44

Catalog number : 3328-100

Quantity: 100

Availability: Yes

Supplier name : Biovis

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About this Product :

Caspase-4 Antibody MonoclonalHost: Mouse D44 antibody storage Gentaur recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Caspase-4 Antibody MonoclonalHost: Mouse D44.
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Caspase-4 Antibody MonoclonalHost: Mouse D44 mus musculus murine Caspase-4 Antibody MonoclonalHost: Mouse D44 detects proteins from variouse species most likely human.
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Caspase-4 Antibody MonoclonalHost: Mouse D44 http://biotech-map.com/aa_search/table_sample.html?q=Mab&filter=
Advisory
To keep the quality and the affinity of the antibodies cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.

More Details about

 

Antibody Target: Caspase-4

Alternative Name: CASP-4, ICH-2 protease, TX protease, ICH2

Host: Mouse

Antibody Type: Monoclonal (Clone D44)

Isotype: Mouse IgG1

Immunogen: Synthetic peptide corresponding to the N-terminus of human Caspase-4

Accession#: P49662

Gene ID: 837

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) immunoaffinity purified mouse IgG in PBS containing 0.5% BSA, 1.5 mM sodium azide and 30% glycerol.

Purification: Affinity purified

Species Reactivity: human

Application: Western blot

Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. 293 cell lysate can be used as a positive control. Detects the 43 kDa human caspase-4

Storage Temp.: -20 °C

Shipping: gel pack

Background Descriptions: The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family, caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis.

Handling: The antibody solution should be gently mixed before use.

Usage: For Research Use Only! Not to be used in humans.

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Pathways :
WP1965: VEGF-receptor Signal Transduction
WP2359: Parkin-Ubiquitin Proteasomal System pathway
WP88: Toll Like Receptor signaling

Related Genes :
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[nef] Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein]
[hppA vppA] Putative K(+)-stimulated pyrophosphate-energized sodium pump (EC 7.2.3.-) (Membrane-bound sodium-translocating pyrophosphatase) (Pyrophosphate-energized inorganic pyrophosphatase) (Na(+)-PPase) (Fragment)
[Dredd DCP2 CG7486] Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
[Casp4 Casp11 Caspl Ich3] Caspase-4 (CASP-4) (EC 3.4.22.64) (Caspase-11) (CASP-11) (Protease ICH-3) [Cleaved into: Caspase-4 subunit p10; Caspase-4 subunit p20]
[Casp2 Ich1 Nedd-2 Nedd2] Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]
[Casp3 Cpp32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[Casp14] Caspase-14 (CASP-14) (EC 3.4.22.-) (Mini-ICE) (MICE) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]
[Casp8] Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
[Casp9 Mch6] Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
[Casp6] Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11]
[Casp1 Il1bc] Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
[Casp7 Lice2 Mch3] Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]
[COI] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)
[cox1] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)
[COI] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)
[COI] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)
[Nlrc4 Card12 Ipaf] NLR family CARD domain-containing protein 4 (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)
[Cflar Cash] CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
[Nlrp1a Card7 Nalp1 Nalp1a Nlrp1] NACHT, LRR and PYD domains-containing protein 1a (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain)
[Casp12] Caspase-12 (CASP-12) (EC 3.4.22.-)
[Nod1 Card4] Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
[Slc39a4 Zip4] Zinc transporter ZIP4 (Activated in W/Wv mouse stomach 2) (mAWMS2) (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4)
[MAPK1 ERK2 PRKM1 PRKM2] Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
[Lyar] Cell growth-regulating nucleolar protein (Ly1 antibody-reactive protein) (Protein expressed in male leptotene and zygotene spermatocytes 264) (MLZ-264)
[rbcL] Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) (Fragment)
[Espl1 Esp1 Kiaa0165] Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)
[CASP14] Caspase-14 (CASP-14) (EC 3.4.22.-) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]
[ampH yaiH b0376 JW5052] D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH (EC 3.4.-.-) (DD-alanine-endopeptidase) (DD-carboxypeptidase) (Penicillin-binding protein AmpH)

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