Product name : Caspase-7 Antibody MonoclonalHost: Mouse B4-G2
Catalog number : 3010-100
Supplier name : Biovis
Data sheet : Ask more or other datasheet now !
Caspase-7 Antibody MonoclonalHost: Mouse B4-G2 mus musculus murine Caspase-7 Antibody MonoclonalHost: Mouse B4-G2 detects proteins from variouse species most likely human.
Caspase-7 Antibody MonoclonalHost: Mouse B4-G2 http://biotech-map.com/aa_search/table_sample.html?q=Mab&filter=
To keep the quality and the affinity of the antibodies cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
SPECIES REACTIVITY: human, mouse, rat
100 μg (0.5 mg/ml) in PBS containing 1 mg/ml BSA and 1.5 mM thimerosal and 50% glycerol.
Store at -20°C. For long term storage, aliquot and refreeze at –70°C. Avoid repeated freeze/defrost cycles.
The caspase family of cysteine proteases plays a key role in apoptosis. Caspase-7, also known as Mch3α , ICE/LAP3 and CMH1, is a 34 kDa protein that is activated during Fas- and TNF-induced apoptosis. Caspase-7 has been identified as a major contributor to the execution phase of cellular apoptosis. It cleaves essential cellular machinery following its own cleavage from an inactive proenzyme to an active heterodimeric form. Caspase-7 is processed by caspase-3, -6, -8, -9, and –10 as well as by Granzyme B.
APPLICATIONS AND USAGE:
Western blot analysis (0.5-2 μg/ml) and immunoprecipitation (4-10 μg/ml). However the optimal conditions should be determined individually.
Detects both pro-caspase-7 (34 kDa) and the large subunit of cleaved caspase-7 (19 kDa) in apoptosis cells on SDS-PAGE immunoblots.
Apoptosis Detection Kits & Reagents
Cell Fractionation System
Cell Proliferation & Senescence
Cell Damage & Repair
Adipocyte & Lipid Transfer
Molecular Biology & Reporter Assays
Growth Factors and Cytokines
Monoclonal and Polyclonal Antibodies
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