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Index / Biovis / DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set Hedgehog (Hh) Signaling Pathway Inhibitors Set /Product Detail : K868-6 DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set Hedgehog (Hh) Signaling Pathway Inhibitors Set
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#K868-6 DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set Hedgehog (Hh) Signaling Pathway Inhibitors Set

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  Price : 582   EUR
660   USD
451   GBP
2444   Zloty
77868   JPY
4488   NOK
4808   SEK
658   CHF

Product name : DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set Hedgehog (Hh) Signaling Pathway Inhibitors Set

Catalog number : K868-6

Quantity: Inhibitors

Availability: Yes

Supplier name : Biovis

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More Details about

 

Alternate Name/Synonyms: Hedgehog (Hh) Signaling Pathway Antagonists Set

Peptide Sequence: N/A

Appearance: Lyophilized solids

Formulation: N/A

CAS Number: See under the individual product

Molecular Formula: See under the individual product

Molecular Weight: See under the individual product

Purity: See under the individual product

Solubility: See under the individual product

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A convenient set consisting of five Hedgehog (Hh) signaling pathway inhibitors. The five inhibitors are: 50 µg of Cyclopamine-KAAD (Cat. No. 1910-50), 5 mg of GANT58 (Cat. No. 1812-5), 5 mg of GDC-0449 (Cat. No. 1890-5), 1 mg of Hh Signaling Pathway Antagonist (Cat. No. 1659-1), 1 mg of JK 184 (Cat. No. 1726-1). Also provided is 25 mg of Tomatidine hydrochloride (Cat. No. 1893-25) that can act as a negative control.

Handling: Protect from light and air

USAGE: For Research Use Only! Not For Use in Humans.

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Pathways :
WP1022: Hedgehog Signaling Pathway
WP1141: Hedgehog Signaling Pathway
WP116: Hedgehog Signaling Pathway
WP1353: Hedgehog Signaling Pathway
WP47: Hedgehog Signaling Pathway
WP492: Hedgehog Signaling Pathway
WP574: Hedgehog Signaling Pathway
WP790: Hedgehog Signaling Pathway
WP905: Hedgehog Signaling Pathway
WP10: IL-9 Signaling Pathway
WP1004: Kit Receptor Signaling Pathway
WP1010: Wnt Signaling Pathway and Pluripotency
WP1011: T Cell Receptor Signaling Pathway
WP1012: IL-7 Signaling Pathway
WP1014: Androgen receptor signaling pathway
WP1016: Wnt Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1029: Notch Signaling Pathway
WP1031: IL-3 Signaling Pathway
WP1037: p38 MAPK Signaling Pathway
WP1044: ErbB signaling pathway
WP1045: TGF-beta Receptor Signaling Pathway
WP1047: TNF-alpha NF-kB Signaling Pathway
WP1048: TGF Beta Signaling Pathway
WP1052: Id Signaling Pathway

Related Genes :
[hh CG4637] Protein hedgehog [Cleaved into: Protein hedgehog N-product (Hh-Np) (N-Hh); Protein hedgehog C-product (Hh-Cp) (C-Hh)]
[SHH] Sonic hedgehog protein (SHH) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)]
[Shh Hhg1] Sonic hedgehog protein (SHH) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)]
[shha shh vhh1] Sonic hedgehog protein A (SHHA) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) (VHH-1) [Cleaved into: Sonic hedgehog protein A N-product (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein N-product) (ShhN)]
[hh GI24573] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GE23980] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GG12458] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GF18029] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GM23589] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GJ22641] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GL23598] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GH23852] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GK12833] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[SHH] Sonic hedgehog protein (SHH) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)]
[Shh Vhh-1] Sonic hedgehog protein (SHH) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)]
[shh] Sonic hedgehog protein (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) (VHH-1) (X-SHH) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)]
[hh-1 GA18321; hh-2 GA29124] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[IHH] Indian hedgehog protein (IHH) (HHG-2) [Cleaved into: Indian hedgehog protein N-product; Indian hedgehog protein C-product]
[Ihh] Indian hedgehog protein (IHH) (HHG-2) [Cleaved into: Indian hedgehog protein N-product; Indian hedgehog protein C-product]
[IHH] Indian hedgehog protein (IHH) [Cleaved into: Indian hedgehog protein N-product; Indian hedgehog protein C-product]
[Dhh] Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product]
[shhb twhh] Tiggy-winkle hedgehog protein (TWHH) (Sonic hedgehog protein B) (SHHB) [Cleaved into: Tiggy-winkle hedgehog protein N-product; Tiggy-winkle hedgehog protein C-product]
[DHH] Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product]
[hh] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[hh GD18403] Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]
[ihog CG9211] Interference hedgehog
[rasp cmn sit ski CG11495] Protein-cysteine N-palmitoyltransferase Rasp (EC 2.3.1.-) (Protein central missing) (Protein sightless) (Protein skinny hedgehog)
[dhh-b hh4] Desert hedgehog protein B (Desert hedgehog protein 2) (DHH-2) (Hedgehog protein 4) (X-HH4) [Cleaved into: Desert hedgehog protein B N-product; Desert hedgehog protein B C-product]
[HHAT MART2 SKI1] Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Melanoma antigen recognized by T-cells 2) (MART-2) (Skinny hedgehog protein 1)
[ptc CG2411] Protein patched (Hedgehog receptor)

Bibliography :
[25473003] A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma.