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Index / Bioquant / Autoimmune diseases: Scl-70,ELISA kit /Product Detail : BQ 043G Autoimmune diseases: Scl-70,ELISA kit
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Autoimmune diseases: Scl-70,ELISA kit

 Price: 403   EUR
457   USD
312   GBP

Product name : Autoimmune diseases: Scl-70,ELISA kit

Catalog number : BQ 043G

Quantity: 96 tests

Availability: Yes

Supplier name : Bioquant

Data sheet Data sheet : Ask more or other datasheet now !

About this Product :

Autoimmune diseases: Scl-70,ELISA kit
It's possible small volumes of the Autoimmune diseases: Scl-70,ELISA kit to stick on the lids and on the walls of the vials due to handling and transportation. If needed, we advise to briefly centrifuge the vials in order to extricate the liquids from the container's cap.

More Details about

Quantity 96 Well Plate
Sample Type Serum or Plasma
The Scl-70 IgG ELISA test system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to ScI-70 in human serum or plasma. Systemic autoimmune disease is characterized by the presence of circulating auto-antibodies directed to a wide variety of cellular antigens. Systemic lupus erythematosis (SLE), commonly referred to as Lupus is the best known of these diseases. Other possible connective tissue diseases include mixed connective tissue disease (MCTD), Sjogren syndrome, sclerodema, and polymyositis/dermatomyositis. The majority can be diagnosed by clinical presentation and their antibody profiles to the various antigens involved, which include dsDNA, SM, RNP, SSA, SSB Scl-70, Jo1 and Histones. Therefore, immunoassays for autoantibodies are useful for diagnostic and prognostic evaluations of autoimmune disease. Scl-70 IgG antibodies react with human topoisomerase I of 100 kd molecular weight as well as its 70 kd fragment. Scl-70 antibodies are present in 20-40% of diffuse scleroderma patients and in about 20% of patients with limited scleroderma. Scl-70 antibodies are sometimes reported in classical SLE without features of scleroderma, which may explain the unexpected co-existence of marker autoantibodies for SLE and scleroderma. Some patients with silica-associated systemic sclerosis (SSc) have Scl-70 antibodies.
Species Human
Info NA



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