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Index / Bioquant / Autoimmune diseases: Sm IgG,ELISA kit /Product Detail : BQ 039G Autoimmune diseases: Sm IgG,ELISA kit
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Autoimmune diseases: Sm IgG,ELISA kit

 Price: 403   EUR
457   USD
312   GBP

Product name : Autoimmune diseases: Sm IgG,ELISA kit

Catalog number : BQ 039G

Quantity: 96 tests

Availability: Yes

Supplier name : Bioquant

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Autoimmune diseases: Sm IgG,ELISA kit
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Quantity 96 Well Plate
Sample Type Serum or Plasma
Description
The Smith (Sm) IgG ELISA test system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to Sm in human serum or plasma. Systemic autoimmune disease is characterized by the presence of circulating auto-antibodies directed to a wide variety of cellular antigens. Systemic lupus erythematosis (SLE), commonly referred to as Lupus is the best known of these diseases. Other possible connective tissue diseases include mixed connective tissue disease (MCTD), Sjogren syndrome, sclerodema, and polymyositis/dermatomyositis. The majority can be diagnosed by clinical presentation and their antibody profiles to the various antigens involved, which include dsDNA, SM, RNP, Ro, La Scl-70, Jo1 and Histones. Therefore, immunoassays for autoantibodies are useful for diagnostic and prognostic evaluations of autoimmune disease. The SM or Smith antigen is composed of nuclear RNA and several polypeptides. Antibodies to SM are present in approximately 30% of patients with SLE (systemic lupus erythematosis). SM is a very specific marker for SLE. SM antibodies are very rare in other autoimmune diseases and normals.
Species Human
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