Product name : Autoimmune diseases: Sm IgG,ELISA kit
Catalog number : BQ 039G
Quantity: 96 tests
Supplier name : Bioquant
Data sheet : Ask more or other datasheet now !
|Quantity||96 Well Plate|
|Sample Type||Serum or Plasma|
The Smith (Sm) IgG ELISA test system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to Sm in human serum or plasma. Systemic autoimmune disease is characterized by the presence of circulating auto-antibodies directed to a wide variety of cellular antigens. Systemic lupus erythematosis (SLE), commonly referred to as Lupus is the best known of these diseases. Other possible connective tissue diseases include mixed connective tissue disease (MCTD), Sjogren syndrome, sclerodema, and polymyositis/dermatomyositis. The majority can be diagnosed by clinical presentation and their antibody profiles to the various antigens involved, which include dsDNA, SM, RNP, Ro, La Scl-70, Jo1 and Histones. Therefore, immunoassays for autoantibodies are useful for diagnostic and prognostic evaluations of autoimmune disease. The SM or Smith antigen is composed of nuclear RNA and several polypeptides. Antibodies to SM are present in approximately 30% of patients with SLE (systemic lupus erythematosis). SM is a very specific marker for SLE. SM antibodies are very rare in other autoimmune diseases and normals.
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