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Index / Bioquant / Autoimmune diseases: SSB IgG,ELISA kit /Product Detail : BQ 041G Autoimmune diseases: SSB IgG,ELISA kit
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Autoimmune diseases: SSB IgG,ELISA kit

 Price: 415   EUR
471   USD
322   GBP

Product name : Autoimmune diseases: SSB IgG,ELISA kit

Catalog number : BQ 041G

Quantity: 96 tests

Availability: Yes

Supplier name : Bioquant

Data sheet Data sheet : Ask more or other datasheet now !

About this Product :

Autoimmune diseases: SSB IgG,ELISA kit
It's possible small volumes of the Autoimmune diseases: SSB IgG,ELISA kit to stick on the lids and on the walls of the vials due to handling and transportation. If needed, we advise to briefly centrifuge the vials in order to extricate the liquids from the container's cap.

More Details about

Quantity 96 Well Plate
Sample Type Serum or Plasma
The SSB (La) IgG ELISA test system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to SSB in human serums or plasma. Systemic autoimmune disease is characterized by the presence of circulating auto-antibodies directed to a wide variety of cellular antigens. Systemic lupus erythematosis (SLE), commonly referred to as Lupus is the best known of these diseases. Other possible connective tissue diseases include mixed connective tissue disease (MCTD), Sjogren syndrome, sclerodema, and polymyositis/dermatomyositis. The majority can be diagnosed by clinical presentation and their antibody profiles to the various antigens involved, which include dsDNA, SM, RNP, SSA, SSB Scl-70, Jo1 and Histones. Therefore, immunoassays for autoantibodies are useful for diagnostic and prognostic evaluations of autoimmune disease. The 48 kd phosphoprotein known as SSB (La) is a transcription termination factor for RNA polymerase III. SSB shuttles between nucleus and cytoplasm and exists both free and as a component of the SSA/SSB ribonucleoprotein cytoplasmic particle. Autoantibodies to SSB are detected by ELISA in ~70-90% of primary and ~50% of secondary Sjögren syndrome as well as in ~25% of SLE and ~80% of subacute cutaneous lupus and in the majority of infants with complete heart block. SSB autoantibodies are found only in sera determined to contain SSA autoantibodies by a sensitive method; this probably reflects the association of the SS-A and SS-B antigens in a macromolecular complex.
Species Human
Info NA


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