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Polyol pathway

pathways : Polyol pathway pathways:

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Related Pathways to "Polyol pathway" content :


Related Genes to "Polyol pathway" content :

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30-110 CBS is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects 0.1 mg
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26-070 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. 0.05 mg
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Pathways :

WP1054: Polyol pathway
WP1170: Polyol pathway
WP1218: Polyol pathway
WP1236: Polyol pathway
WP1265: Polyol pathway
WP1303: Polyol pathway
WP1375: Polyol pathway
WP1572: Polyol pathway
WP690: Polyol pathway
WP817: Polyol pathway
WP936: Polyol pathway
WP1: Statin Pathway
WP10: IL-9 Signaling Pathway
WP1004: Kit Receptor Signaling Pathway
WP1010: Wnt Signaling Pathway and Pluripotency
WP1011: T Cell Receptor Signaling Pathway
WP1012: IL-7 Signaling Pathway
WP1014: Androgen receptor signaling pathway
WP1016: Wnt Signaling Pathway
WP1019: FAS pathway and Stress induction of HSP regulation
WP1022: Hedgehog Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1028: Pentose Phosphate Pathway
WP1029: Notch Signaling Pathway
WP1031: IL-3 Signaling Pathway

Related Genes :
[PLT5 At3g18830 MVE11.10 MVE11.22] Polyol transporter 5 (Protein POLYOL TRANSPORTER 5) (AtPLT5) (Sugar-proton symporter PLT5)
[TFPI LACI TFPI1] Tissue factor pathway inhibitor (TFPI) (Extrinsic pathway inhibitor) (EPI) (Lipoprotein-associated coagulation inhibitor) (LACI)
[DUSP19 DUSP17 LMWDSP3 SKRP1] Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)
[GPS2] G protein pathway suppressor 2 (GPS-2)
[Gps2] G protein pathway suppressor 2 (GPS-2)
[Ecsit Sitpec] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
[Fem1b F1aa Kiaa0396] Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha) (mt-Fem)
[FEM1B F1AA KIAA0396] Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)
[TFPI2] Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5)
[WISP1 CCN4] WNT1-inducible-signaling pathway protein 1 (WISP-1) (CCN family member 4) (Wnt-1-induced secreted protein)
[SRM1 MTR1 PRP20 YGL097W] Guanine nucleotide exchange factor SRM1 (Pheromone response pathway component SRM1) (Pre-mRNA-processing protein 20) (Regulator of chromosome condensation) (Suppressor of receptor mutations 1) (mRNA transport protein 1)
[ECSIT] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
[geoA] Geraniol dehydrogenase (GeDH) (EC 1.1.1.347) (Geraniol oxidation pathway protein A) (Perillyl-alcohol dehydrogenase) (EC 1.1.1.144)
[WISP3 CCN6 UNQ462/PRO790/PRO956] WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)
[Dusp19 Skrp1] Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1)
[dcr1 SPCC188.13c SPCC584.10c] Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)]
[VTE1 SXD1 At4g32770 F4D11.30] Tocopherol cyclase, chloroplastic (EC 5.5.1.24) (Sucrose export defective 1) (Vitamin E pathway gene 1 protein)
[ago1 csp9 SPCC736.11] Protein argonaute (Cell cycle control protein ago1) (Eukaryotic translation initiation factor 2C 2-like protein ago1) (PAZ Piwi domain protein ago1) (Protein slicer) (RNA interference pathway protein ago1)
[EPS8L2 EPS8R2 PP13181] Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)
[HPT1 TPT1 VTE2-1 At2g18950 F19F24.15] Homogentisate phytyltransferase 1, chloroplastic (AtHPT1) (EC 2.5.1.115) (Tocopherol polyprenyltransferase 1) (Vitamin E pathway gene 2-1 protein) (AtVTE2-1)
[SORD] Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)
[GDI1 SEC19 YER136W] Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
[DTX47 EDS5 IAP1 SCORD3 SID1 At4g39030 F19H22.130] Protein DETOXIFICATION 47, chloroplastic (AtDTX47) (Multidrug and toxic compound extrusion protein 47) (MATE protein 47) (Protein ENHANCED DISEASE SUSCEPTIBILITY 5) (Protein EDS5) (Protein IMPORTANT FOR THE ARR PATHWAY 1) (Protein IAP1) (Protein SALICYLIC ACID INDUCTION DEFICIENT 1) (Protein SID1) (Protein SUSCEPTIBLE TO CORONATINE-DEFICIENT PST DC3000 3) (Protein SCORD3)
[GPS1 COPS1 CSN1] COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
[SEPT4 ARTS PNUTL2 SEP4 hucep-7] Septin-4 (Apoptosis-related protein in the TGF-beta signaling pathway) (ARTS) (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Cerebral protein 7) (Peanut-like protein 2)
[EPS8L1 DRC3 EPS8R1 PP10566] Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1)
[Steap3 Tsap6] Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Protein nm1054) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6)
[STEAP3 TSAP6] Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde)
[sldA] Glycerol dehydrogenase large subunit (EC 1.1.99.22) (D-arabitol dehydrogenase large subunit) (ARDH) (D-sorbitol dehydrogenase subunit SldA) (SLDH) (Gluconate/polyol dehydrogenase large subunit)
[Tfpi] Tissue factor pathway inhibitor (TFPI) (Extrinsic pathway inhibitor) (EPI) (Lipoprotein-associated coagulation inhibitor) (LACI)

Bibliography :
[30879203] Galactitol catabolism in Sinorhizobium meliloti is dependent on a chromosomally encoded sorbitol dehydrogenase and a pSymB-encoded operon necessary for tagatose catabolism.
[30813879] Review of Diabetic Polyneuropathy: Pathogenesis, Diagnosis and Management According to the Consensus of Egyptian Experts.
[30766472] Neurons and Microglia; A Sickly-Sweet Duo in Diabetic Pain Neuropathy.
[30760060] Aldose reductase inhibitors: 2013-present.
[30707979] Cooperative regulation of mouse aldose reductase (AKR1B3) gene transcription by Nrf2, TonEBP, and c-jun.
[30689163] 3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats: A Role of Aldose Reductase.
[30668344] Tannins and vascular complications of Diabetes: An update.
[30651350] Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats.
[30611193] De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim.
[30581303] Role of oxidative stress, inflammation, hypoxia and angiogenesis in the development of diabetic retinopathy.