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Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Phase I, non P450

pathways : Phase I, non P450 pathways:

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Related Pathways to "Phase I, non P450" content :


Related Genes to "Phase I, non P450" content :

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Pathways :

WP1021: Phase I, non P450
WP1291: Phase I, non P450
WP1573: Phase I, non P450
WP1077: cytochrome P450
WP904: Phase I, non P450
WP1213: Phase I, non P450
WP791: Phase I, non P450
WP1255: Phase I, non P450
WP136: Phase I, non P450
WP1140: Phase I, non P450
WP812: TGF Beta Signaling Pathway
WP1713: Two-component system
WP117: GPCRs, Other
WP1835: Interferon alpha/beta signaling
WP2432: Spinal Cord Injury
WP439: Insulin Signaling
WP520: G13 Signaling Pathway
WP2006: Squamous cell TarBase
WP1703: Streptomycin biosynthesis
WP878: EPO Receptor Signaling
WP1354: B Cell Receptor Signaling Pathway
WP833: Cholesterol Biosynthesis
WP2365: Inhibition of ricin by drugs
WP313: Signaling of Hepatocyte Growth Factor Receptor
WP2429: Cancer prevention Q

Related Genes :
[ERG11 CYP51 YHR007C] Lanosterol 14-alpha demethylase (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase)
[cypB cyp102A3 yrhJ BSU27160] Bifunctional cytochrome P450/NADPH--P450 reductase 2 (CYP102A3) (Fatty acid hydroxylase CypB) (Flavocytochrome P450 102A3) [Includes: Cytochrome P450 102A3 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)]
[cypD cyp102A2 yetO yfnJ BSU07250] Bifunctional cytochrome P450/NADPH--P450 reductase 1 (CYP102A2) (Fatty acid hydroxylase CypD) (Flavocytochrome P450 102A2) [Includes: Cytochrome P450 102A2 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)]
[CYP3A4 CYP3A3] Cytochrome P450 3A4 (EC 1.14.14.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55)
[CYP2C9 CYP2C10] Cytochrome P450 2C9 (EC 1.14.14.-) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC9) (Cholesterol 25-hydroxylase) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase)
[CYP2C8] Cytochrome P450 2C8 (EC 1.14.14.-) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase)
[CYP26B1 CYP26A2 P450RAI2] Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome)
[CYP1A1] Cytochrome P450 1A1 (CYPIA1) (EC 1.14.14.-) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP2A6 CYP2A3] Cytochrome P450 2A6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I))
[CYP1A2] Cytochrome P450 1A2 (EC 1.14.14.-) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[Cyp26b1] Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2)
[CYP2C19] Cytochrome P450 2C19 (EC 1.14.14.-) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC17) (CYPIIC19) (Cytochrome P450-11A) (Cytochrome P450-254C) (Fenbendazole monooxygenase (4'-hydroxylating)) (EC 1.14.14.75) (Mephenytoin 4-hydroxylase)
[CYP2B6] Cytochrome P450 2B6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIB6) (Cytochrome P450 IIB1)
[CYP2E1 CYP2E] Cytochrome P450 2E1 (EC 1.14.14.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J)
[NCP1 CPR1 NCPR1 PRD1 YHR042W] NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
[cyp102A1 cyp102 BG04_163] Bifunctional cytochrome P450/NADPH--P450 reductase (Cytochrome P450(BM-3)) (Cytochrome P450BM-3) (Fatty acid monooxygenase) (Flavocytochrome P450 BM3) [Includes: Cytochrome P450 102A1 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)]
[CYP2D6 CYP2DL1] Cytochrome P450 2D6 (EC 1.14.14.-) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase)
[Cyp1a1 Cyp1a-1] Cytochrome P450 1A1 (CYP1A1) (EC 1.14.14.-) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Cytochrome P450MT2) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) [Cleaved into: Cytochrome P450MT2A; Cytochrome P450MT2B]
[CYP1A1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P-450 PHPAH1) (Cytochrome P450 isozyme 6) (Cytochrome P450 LM6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP505] Bifunctional cytochrome P450/NADPH--P450 reductase (Cytochrome P450foxy) (Fatty acid omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)]
[Cyp2d4 Cyp2d-18 Cyp2d-4 Cyp2d18] Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID18) (CYPIID4) (Cytochrome P450 2D-29) (Cytochrome P450 2D-35) (Cytochrome P450 2D18) (Cytochrome P450-CMF3) (Cytochrome P450-DB4) (Debrisoquine 4-hydroxylase)
[CYP3A5] Cytochrome P450 3A5 (EC 1.14.14.-) (CYPIIIA5) (Cytochrome P450-PCN3)
[CYP79F1 BUS1 SPS1 At1g16410 F3O9.21] Dihomomethionine N-hydroxylase (EC 1.14.14.42) (Cytochrome P450 79F1) (Protein BUSHY 1) (Protein SUPERSHOOT 1) (Trihomomethionine N-hydroxylase)
[CYP1A1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P-450MC) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[Cyp2b1 Cyp2b-1] Cytochrome P450 2B1 (EC 1.14.14.1) (CYPIIB1) (Cytochrome P450-B) (Cytochrome P450b) (Cytochrome P450-LM2) (Cytochrome P450-PB1) (Cytochrome P450-PB2)
[CYP1A2] Cytochrome P450 1A2 (EC 1.14.14.-) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P450 isozyme 4) (Cytochrome P450 LM4) (Cytochrome P450-PM4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[Cyp1a1 Cyp1a-1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP1A1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (DAH1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP1A1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Cytochrome P4501A1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP1A1] Cytochrome P450 1A1 (EC 1.14.14.-) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)

Bibliography :
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[31388941] Clinical Pharmacodynamics, Pharmacokinetics, and Drug Interaction Profile of Doravirine.
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[31362140] 3-D culture and endothelial cells improve maturity of human pluripotent stem cell-derived hepatocytes.
[31321631] Effect of DS-8500a, a Novel G Protein-Coupled Receptor 119 Agonist, on the Pharmacokinetics of Rosuvastatin and Atorvastatin in Healthy Subjects.
[31313341] Dose-dependent chemopreventive effects of citronellol in DMBA-induced breast cancer among rats.
[31299982] A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice.
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