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Physiological and Pathological Hypertrophy of the Heart

pathways : Physiological and Pathological Hypertrophy of the Heart pathways:

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Pathways :

WP1528: Physiological and Pathological Hypertrophy of the Heart
WP1100: Hypertrophy Model
WP1327: Hypertrophy Model
WP1526: Cardiac Hypertrophy: miR-208
WP1544: MicroRNAs in cardiomyocyte hypertrophy
WP1553: heart diagrams
WP1559: TFs Regulate miRNAs related to cardiac hypertrophy
WP1560: MicroRNAs in cardiomyocyte hypertrophy
WP1591: Heart Development
WP202: Hypertrophy Model
WP2067: Heart Development
WP2080: TFs Regulate miRNAs related to cardiac hypertrophy
WP442: Hypertrophy Model
WP516: Hypertrophy Model
WP756: Hypertrophy Model
WP864: Hypertrophy Model
WP982: Hypertrophy Model

Related Genes :
[Hand2 Dhand Hed Thing2] Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2)
[HAND2 BHLHA26 DHAND] Heart- and neural crest derivatives-expressed protein 2 (Class A basic helix-loop-helix protein 26) (bHLHa26) (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND)
[GATA4] Transcription factor GATA-4 (GATA-binding factor 4)
[GJA1 GJAL] Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
[ASAH1 ASAH HSD-33 HSD33] Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]
[FHL1 SLIM1] Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)
[MYBPC3] Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)
[Camk2d Kiaa4163] Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
[CACNA1C CACH2 CACN2 CACNL1A1 CCHL1A1] Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
[NKX2-5 CSX NKX2.5 NKX2E] Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E)
[KCNJ5 GIRK4] G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)
[MYOC GLC1A TIGR] Myocilin (Myocilin 55 kDa subunit) (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)]
[Cmya5 Sr553 Srfsd Tims] Cardiomyopathy-associated protein 5 (Heart and skeletal muscle-specific and sprouty domain-containing) (Myospryn) (Stretch-response protein 553) (Stretch-responsive fibronectin protein type 3) (TRIM-like protein)
[Hand1 Ehand Hxt Thing1] Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1)
[Fabp3] Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP)
[JPH2 JP2] Junctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)]
[Cib1 Cib Kip Prkdcip] Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP)
[FABP3 FABP11 MDGI] Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI) (Muscle fatty acid-binding protein) (M-FABP)
[HAND1 BHLHA27 EHAND] Heart- and neural crest derivatives-expressed protein 1 (Class A basic helix-loop-helix protein 27) (bHLHa27) (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND)
[hand2 dhand] Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND)
[SCN5A] Sodium channel protein type 5 subunit alpha (HH1) (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5)
[PRKD1 PKD PKD1 PRKCM] Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
[Fabp3 Fabph1] Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI)
[TRIM63 IRF MURF1 RNF28 SMRZ] E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
[Cacna1c Cach2 Cacn2 Cacnl1a1 Cchl1a1] Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (MELC-CC) (Mouse brain class C) (MBC) (Voltage-gated calcium channel subunit alpha Cav1.2)
[GATA5] Transcription factor GATA-5 (GATA-binding factor 5)
[TCAP] Telethonin (Titin cap protein)
[CORIN CRN TMPRSS10] Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Heart-specific serine proteinase ATC2) (Pro-ANP-converting enzyme) (Transmembrane protease serine 10) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment]
[MYH7 MYHCB] Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
[Prkd1 Pkcm Pkd Prkcm] Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)

Bibliography :
[30958896] Melatonin Differentially Regulates Pathological and Physiological Cardiac Hypertrophy: Crucial Role of Circadian Nuclear Receptor RORĪ± Signaling.
[30922063] Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2 -Mediated Paracrine Signaling.
[30897106] Testosterone deficiency reduces the effects of late cardiac remodeling after acute myocardial infarction in rats.
[30895179] Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure.
[30848206] Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart.
[30842884] Alteration in cardiac PI3K/Akt/mTOR and ERK signaling pathways with the use of growth hormone and swimming, and the roles of miR21 and miR133.
[30831134] Multiple roles of KLF15 in the heart: Underlying mechanisms and therapeutic implications.
[30830529] Regulation of microRNAs by molecular hydrogen contributes to the prevention of radiation-induced damage in the rat myocardium.
[30818334] JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function.
[30781751] Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.