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Catalog number Product name Quantity
4-20354 Neural Dissociation System 4 (Cerebella neurons Dorsa horn neurons Neurons, sympathetic Precursor Spinal), Mouse and Rat ea
852238-97-2 S-Nicotine-5-carboxaldehyde S-Nicotine-5-carboxald 1g
96055-45-7 Nicotine N-oxide Nicotine polyacrilex 1g
orb61675 L-Nicotine L-Nicotine For research use only. 20 mg
4-20352 Neural Dissociation System 2 (Neurons, Neurons and glial,Retina), Mouse and Rat ea
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N427510 (1’S,2'S)-Nicotine 1'-Oxide and (1’R,2'S)-Nicotine 1'-Oxide Mixture C10H14N2O CAS: 10 mg
28-261 P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth mu 0.1 mg
SC15000 Dopaminergic Neuron Differentiation Kit
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2624-48-8 nicotine bi-l-(+)-tartrate -nicotine bi-l-(+)-tartrate 1g
29790-52-1 Nicotine salicylate Nicotine salicylate 1g
65-30-5 Nicotine sulfate Nicotine Sulfate 40 percent s 1g
30-276 GDE1 has glycerophosphoinositol phosphodiesterase activity. It has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. 0.05 mg
25-002 KLF16 is a transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. KLF16 modulates dopaminergic transmission in the brain. 0.05 mg
25-543 KLF16 is a transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. KLF16 modulates dopaminergic transmission in the brain. 0.05 mg
K3011-1 P450 Demethylation Activity kit (2 plate) The Cytochrome P450 Activity kit is designed to measure the enzymatic activity of demethylation processes carried out by Cytochrome P450. The unique feature o 192 rxns
SDS05 TALEN vector construction plus activity determination (one pair activity proved)
27-178 The function of this protein is binding , oxidoreductase activity ,and transcription repressor activity. 0.05 mg
DT1001 Human tPA Activity & ELISA Duro Kit (Measure activity & protein concentration in one assay) 96 well plate
65-30-5 Nicotine sulfate Nicotine sulfate 1g
M75976960 S-(-)-Nicotine CAS: [54-11-5] 25 g
63-30-5 Nicotine sulfate Nicotine sulfate 1g
24332-62 Nicotine CAS: 54-11-5 25ML

Pathways :

WP1602: Nicotine Activity on Dopaminergic Neurons
WP2083: Nicotine Activity on Dopaminergic Neurons
WP1603: Nicotine Activity on Chromaffin Cells
WP1401: Neurotransm. release in cholinergic motor neurons
WP1455: Serotonin Transporter Activity
WP1488: CFTR activity in the plasma membrane
WP1600: Nicotine metabolism
WP1601: Fluoropyrimidine Activity
WP1765: Mechanosensory inputs influence pharyngeal activity via ivermectin sensitivity genes.
WP1899: Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
WP2344: vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) biosynthesis and salvage pathway
WP259: Nifedipine Activity

Related Genes :
[Arc] Activity-regulated cytoskeleton-associated protein (mArc) (Activity-regulated gene 3.1 protein) (ARC/ARG3.1) (Arg3.1)
[Pacsin1 Pacsin] Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
[Arc] Activity-regulated cytoskeleton-associated protein (Activity-regulated gene 3.1 protein) (ARC/ARG3.1) (Arg3.1)
[CASP3 CPP32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[Casp3 Cpp32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[Casp3 Cpp32] Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (IRP) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
[ARC KIAA0278] Activity-regulated cytoskeleton-associated protein (hArc) (Activity-regulated gene 3.1 protein homolog) (ARC/ARG3.1) (Arg3.1)
[ARC] Activity-regulated cytoskeleton-associated protein (Activity-regulated gene 3.1 protein homolog) (ARC/ARG3.1) (Arg3.1)
[opa1] Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (120 kDa G protein expressed in motor neurons) (Optic atrophy protein 1 homolog) (mG120) [Cleaved into: Dynamin-like 120 kDa protein, form S1]
[Th] Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
[neurog1 neurod3 ngn1 ngr1] Neurogenin-1 (NGN-1) (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenin-related protein 1)
[Pitx3] Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3)
[Park7] Protein/nucleic acid deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase) (Parkinson disease protein 7 homolog) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1)
[FMO3] Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (EC 1.14.14.73) (Dimethylaniline oxidase 3) (FMO II) (FMO form 2) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)
[Fzd3] Frizzled-3 (Fz-3) (mFz3)
[MANF ARMET ARP] Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET)
[NRG1 GGF HGL HRGA NDF SMDF] Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]
[Ppp1r9b] Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
[DNAJC6 KIAA0473] Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6)
[Fmo3] Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (EC 1.14.14.73) (Dimethylaniline oxidase 3) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)
[Pacsin2] Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II)
[PACSIN3] Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
[nboR] Nicotine blue oxidoreductase (EC 1.1.1.328)
[Arc1 CG12505] Activity-regulated cytoskeleton associated protein 1 (dArc1)
[FMO3] Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (EC 1.14.14.73) (Dimethylaniline oxidase 3) (FMO 1D1) (FMO II) (FMO form 2) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)
[Fmo3] Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (EC 1.14.14.73) (Dimethylaniline oxidase 3) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)
[PACSIN2] Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II)
[Pitx3 Ptx3] Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3)
[Ppp1r9b] Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
[PRKN PARK2] E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)

Bibliography :
[30529197] α4β2 Nicotinic receptor desensitizing compounds can decrease self-administration of cocaine and methamphetamine in rats.
[30508607] Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons.
[30055209] Combined early life stressors: Prenatal nicotine and maternal deprivation interact to influence affective and drug seeking behavioral phenotypes in rats.
[30030679] Prevention of progression in Parkinson's disease.
[30006684] Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson's Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism.
[29941445] Complex Control of Striatal Neurotransmission by Nicotinic Acetylcholine Receptors via Excitatory Inputs onto Medium Spiny Neurons.
[29940207] Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit.
[29910731] Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons.
[29888787] c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo.
[29308644] Near-Infrared Fluorescent Nanoprobes for Revealing the Role of Dopamine in Drug Addiction.