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Related products :

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25-029 PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. 0.05 mg
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Pathways :

WP2217: Pyruvate metabolism
WP1893: Pyruvate metabolism and Citric Acid (TCA) cycle
WP1695: Pyruvate metabolism
WP1604: Codeine and morphine metabolism
WP1689: Porphyrin and chlorophyll metabolism
WP1891: Prostanoid metabolism
WP435: One Carbon Metabolism
WP925: Aflatoxin B1 metabolism
WP100: Glutathione metabolism
WP1355: One Carbon Metabolism
WP1645: Ether lipid metabolism
WP1788: Bile acid and bile salt metabolism
WP240: Alanine and aspartate metabolism
WP699: Aflatoxin B1 metabolism
WP1169: Estrogen metabolism
WP1653: Galactose metabolism
WP1847: Metabolism of amino acids and derivatives
WP253: Glycolysis
WP755: Nuclear receptors in lipid metabolism and toxicity
WP1203: One Carbon Metabolism
WP1619: Amino sugar and nucleotide sugar metabolism
WP1694: Pyrimidine metabolism
WP1946: Cori Cycle
WP469: Glutathione metabolism
WP981: Nuclear receptors in lipid metabolism and toxicity

Related Genes :
[PKP2 YGL059W] [Pyruvate dehydrogenase (acetyl-transferring)] kinase 2, mitochondrial (PDK 2) (Pyruvate dehydrogenase kinase 2) (EC 2.7.11.2) (Protein kinase of PDH protein 2) (Pyruvate dehydrogenase complex kinase 2) (PDC kinase 2) ([Pyruvate dehydrogenase [lipoamide]] kinase 2)
[PKP1 YIL042C] [Pyruvate dehydrogenase (acetyl-transferring)] kinase 1, mitochondrial (PDK 1) (Pyruvate dehydrogenase kinase 1) (EC 2.7.11.2) (Protein kinase of PDH protein 1) (Pyruvate dehydrogenase complex kinase 1) (PDC kinase 1) ([Pyruvate dehydrogenase [lipoamide]] kinase 1)
[DLAT DLTA] Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
[Dlat] Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
[PDHX PDX1] Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)
[LAT1 ODP2 PDA2 YNL071W N2374] Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
[kgd Rv1248c] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
[Pdk4] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
[PDK4 PDHK4] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
[PKM OIP3 PK2 PK3 PKM2] Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58)
[PDK3 PDHK3] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3)
[Pdk4] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
[Pdk2] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)
[PDK2 PDHK2] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)
[PDK1 PDHK1] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
[Pdk2] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)
[Pdk1 Pdh] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (PDK p48) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
[PPDK PDK] Pyruvate, phosphate dikinase, chloroplastic (EC 2.7.9.1) (Cold-sensitive pyruvate, orthophosphate dikinase) (Pyruvate, orthophosphate dikinase)
[Pdk1] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
[] Pyruvate, phosphate dikinase, chloroplastic (EC 2.7.9.1) (Cold-sensitive pyruvate, orthophosphate dikinase) (Pyruvate, orthophosphate dikinase)
[THI3 KID1 YDL080C] Thiamine metabolism regulatory protein THI3 (EC 4.1.1.72) (Keto isocaproate decarboxylase 1) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC)
[PDA1 YER178W] Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 alpha) (PDHE1-A)
[PNO] Pyruvate dehydrogenase [NADP(+)], mitochondrial (EC 1.2.1.51) (Aquacobalamin reductase [NADPH]) (EgPNOmt) (Pyruvate:NADP(+) oxidoreductase)
[LPD1 DHLP1 YFL018C] Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine decarboxylase complex subunit L) (Lipoamide dehydrogenase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex E3 component)
[AGXT2 AGT2] Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)
[Moth_0064] Pyruvate:ferredoxin oxidoreductase (PFOR) (EC 1.2.7.1) (Pyruvate synthase)
[PPDK1 C4PPDKZM1 CYPPDKZM1 PPDK2] Pyruvate, phosphate dikinase 1, chloroplastic (EC 2.7.9.1) (Pyruvate, orthophosphate dikinase 1)
[PDK PDHK YA5 At3g06483 F24P17.1 F5E6.19] [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial (AtPDHK) (Pyruvate dehydrogenase kinase) (EC 2.7.11.2)
[NPL C1orf13] N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase)
[PPDK PDK] Pyruvate, phosphate dikinase, chloroplastic (EC 2.7.9.1) (Pyruvate, orthophosphate dikinase)

Bibliography :
[34687175] Impact of Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocellular Carcinoma: Cancer Metabolism and Immune Status.
[34687086] Dynamic C MR spectroscopy as an alternative to imaging for assessing cerebral metabolism using hyperpolarized pyruvate in humans.
[34684271] The Effect of Impaired Polyamine Transport on Pneumococcal Transcriptome.
[34684116] Effect of Vitamin D Supplementation on Muscle Status in Old Patients Recovering from COVID-19 Infection.
[34681749] Hydro-Electro Hybrid Priming Promotes Carrot ( L.) Seed Germination by Activating Lipid Utilization and Respiratory Metabolism.
[34681099] Warburg Effect, Glutamine, Succinate, Alanine, When Oxygen Matters.
[34681062] First Metabolic Insights into -Infected Bovine Small Intestinal Explants Studied under Physioxic Conditions.
[34680207] Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells.
[34679734] Biochemical Evaluation of the Effects of Hydroxyurea in Vitro on Red Blood Cells.
[34676828] Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis.