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Valine, leucine and isoleucine degradation

pathways : Valine, leucine and isoleucine degradation pathways:

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Related Pathways to "Valine, leucine and isoleucine degradation" content :


Related Genes to "Valine, leucine and isoleucine degradation" content :

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Related products :

Catalog number Product name Quantity
2130-99-6 N-Cbz-L-Isoleucine-p-nitrophenyl ester N-Cbz-L-Isoleucine-p-ni 1g
10512-93-3 Z-L-Valine 4-nitrophenyl ester Z-L-Valine 4-nitropheny 1g
MEL12-500ML Cell Culture Media,Minimum Essentials Medium,EMEM,With Earle's salts, L-glutamine, and 92 mg_L D-valine substituted for L-valine. 500ml
orb62031 D-Valine D-Valine For research use only. 400 g
37869-33-3 N-Dodecanoyl-valine mono sodium salt N-dodecanoyl- Valine 1g
58185-39-0 N-Tetradecanoyl-Valine mono sodium sa N-tetradecanoyl- Valine 1g
93839-03-3 N-acetyl-L-valine, compound with 2-(dim N-acetyl-L-valine, comp 1g
30-956 Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic con 0.05 mg
30-957 Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic con 0.05 mg
158257-41-1 Valine NCA Valine NCA 1g
3588-63-4 n-Cbz-dl -valine n-Cbz-dl -valine 1g
27-171 ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is involved in ITPR1 degradation by the ERAD pathway. 0.05 mg
31-050 MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. It inhibits degradation of MDM2. It can reverse MDM2-targeted degradation of p53 w 0.05 mg
19461-38-2 N-Glycyl-L-isoleucine n-glycyl-l-isoleucine 1g
29588-88-3 Phthaloyl-L-isoleucine Phthaloyl-L-isoleucine 1g
4125-98-8 N-a-Methyl-L-isoleucine N-a-Methyl-L-isoleucine 1g
3077-46-1 N-Acetyl-L-Isoleucine N-Acetyl-L-Isoleucine 1g
6001-78-8 4_Hydroxy Isoleucine 4_Hydroxy Isoleucine 1g
31-051 MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. inhibits degradation of MDM2. It can reverse MDM2-targeted degradation of p53 whil 0.1 mg
14379-28-3 N-dodecanoyl-Valine N-dodecanoyl-Valine 1g
17916-88-0 N-Acetyl-d-valine N-Acetyl-d-valine 1g
3067-19-4 N-Acetyl-DL-valine N-Acetyl-DL-valine 1g
4289-97-8 N-Formyl-L-valine N-Formyl-L-valine 1g
14379-30-7 N-Tetradecanoyl-Valine N-tetradecanoyl- Valine 1g
88930-14-7 N-Methyl-D-valine N-Methyl-D-valine 1g

Pathways :

WP1717: Valine, leucine and isoleucine degradation
WP1451: Valine, leucine and isoleucine degradation
WP198: Isoleucine, Leucine, and Valine biosynthesis
WP1716: Valine, leucine and isoleucine biosynthesis
WP359: Isoleucine and Valine biosynthesis
WP354: Leucine Degradation
WP178: Isoleucine Degradation
WP1636: Caprolactam degradation
WP311: Synthesis and Degradation of Ketone Bodies
WP1015: Synthesis and Degradation of Ketone Bodies
WP172: m-cresol degradation
WP543: Synthesis and Degradation of Ketone Bodies
WP1196: Proteasome Degradation
WP180: Leucine Biosynthesis
WP559: Glutamate degradation VII
WP1649: Fluorene degradation
WP345: Glycine Degradation
WP1655: Geraniol degradation
WP158: Proteasome Degradation
WP70: Trehalose Degradation, Low Osmolarity
WP1614: 1- and 2-Methylnaphthalene degradation
WP2231: Degradation of apoptotic cells
WP898: Synthesis and Degradation of Ketone Bodies
WP1698: RNA degradation
WP440: Sulfur degradation

Related Genes :
[braC PA1074] Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein (LIVAT-BP) (Leu/Ile/Val/Thr/Ala-binding protein)
[VAT1 At5g16290 MQK4.1] Acetolactate synthase small subunit 1, chloroplastic (Acetohydroxy-acid synthase small subunit) (AHAS) (ALS) (Protein valine-tolerant 1)
[CYP94B3 At3g48520 T8P19.30] Cytochrome P450 94B3 (EC 1.14.14.48) (Jasmonoyl-L-amino acid 12-hydroxylase) (Jasmonoyl-isoleucine-12-hydroxylase)
[vdh SCO4089 SCD25.25c] Valine dehydrogenase (ValDH) (EC 1.4.1.23)
[ldh] Leucine dehydrogenase (LeuDH) (EC 1.4.1.9)
[grsB grs2] Gramicidin S synthase 2 (Gramicidin S synthase II) [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)]
[ileS ilvS b0026 JW0024] Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
[tycC] Tyrocidine synthase 3 (Tyrocidine synthase III) [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)]
[grsB grs2] Gramicidin S synthase 2 (Gramicidin S synthase II) [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)]
[valS] Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)
[bacA] Bacitracin synthase 1 (BA1) [Includes: ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-dependent glutamate adenylase (GluA) (Glutamate activase); ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); Glutamate racemase (EC 5.1.1.3)]
[VIP] VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]
[CmaA ALO37_100711] L-allo-isoleucine:holo-[CmaA peptidyl-carrier protein] ligase (EC 6.2.1.46) (Adenylation activation enzyme) (Coronamic acid synthetase CmaA)
[ileS TTHA1067] Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
[CYP79D1] Valine N-monooxygenase 1 (EC 1.14.14.38) (Cytochrome P450 79D1)
[lgrA] Linear gramicidin synthase subunit A [Includes: ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)]
[BCAT3 At3g49680 T16K5.30] Branched-chain-amino-acid aminotransferase 3, chloroplastic (Atbcat-3) (EC 2.6.1.42) (EC 2.6.1.88)
[THI3 KID1 YDL080C] Thiamine metabolism regulatory protein THI3 (EC 4.1.1.72) (Keto isocaproate decarboxylase 1) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC)
[ldh] Leucine dehydrogenase (LeuDH) (EC 1.4.1.9)
[BCAT1] Branched-chain amino acid aminotransferase 1, mitochondrial (HlBCAT1) (EC 2.6.1.42)
[BCAT2] Branched-chain amino acid aminotransferase 2, chloroplastic (HlBCAT2) (EC 2.6.1.42)
[PDC6 YGR087C] Pyruvate decarboxylase isozyme 3 (EC 4.1.1.-) (EC 4.1.1.43) (EC 4.1.1.72) (EC 4.1.1.74) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC)
[PDC1 YLR044C L2104] Pyruvate decarboxylase isozyme 1 (EC 4.1.1.-) (EC 4.1.1.43) (EC 4.1.1.72) (EC 4.1.1.74) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC)
[PDC5 YLR134W L3133 L9606.7] Pyruvate decarboxylase isozyme 2 (EC 4.1.1.-) (EC 4.1.1.43) (EC 4.1.1.72) (EC 4.1.1.74) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC)
[MAP3K12 ZPK] Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)
[Map3k12 Zpk] Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)
[lgrB] Linear gramicidin synthase subunit B [Includes: ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-)]
[Map3k12 Muk] Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)
[CARMIL2 LRRC16C RLTPR] Capping protein, Arp2/3 and myosin-I linker protein 2 (Capping protein regulator and myosin 1 linker 2) (F-actin-uncapping protein RLTPR) (Leucine-rich repeat-containing protein 16C) (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein)
[BLZF1 JEM1] Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor)

Bibliography :
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[31303893] Improving isobutanol production with the yeast by successively blocking competing metabolic pathways as well as ethanol and glycerol formation.
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[31164448] Antibiotic Exposure Has Sex-Dependent Effects on the Gut Microbiota and Metabolism of Short-Chain Fatty Acids and Amino Acids in Mice.
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