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ABC-family proteins mediated transport

pathways : ABC-family proteins mediated transport pathways:

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Catalog number Product name Quantity
30-776 In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been 0.05 mg
26-911 The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons 0.05 mg
26-913 The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons 0.05 mg
29-961 Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the meth 0.1 mg
27-967 KIF5A is a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in 0.05 mg
27-979 KIF22 a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The 0.1 mg
29-719 GEM belongs to the RAD_GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transdu 0.1 mg
28-883 WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. 0.05 mg
27-837 Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled recept 0.05 mg
27-838 Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled recept 0.1 mg
28-080 WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. 0.1 mg
27-981 KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependent motor proteins to transport essential cellular components along axonal and 0.05 mg
29-310 HSP90B1 belongs to the heat shock protein 90 family. It is molecular chaperone that functions in the processing and transport of secreted proteins. 0.1 mg
30-540 SLC22A23 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes.SLC22A23 belongs to a large family 0.1 mg
28-324 The C_EBP family of transcription factors regulates viral and cellular CCAAT_enhancer element-mediated transcription. C_EBP proteins contain the bZIP region, which is characterized by two motifs in th 0.05 mg
29-006 AKAP8L could play a role in constitutive transport element (CTE)-mediated gene expression. It does not seem to be implicated in the binding of regulatory subunit II of PKA. It may be involved in nucle 0.1 mg
26-399 CLN8 is a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endop 0.05 mg
25-682 FZD10 is a member of the frizzled family. Members of this family are 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most f 0.05 mg
25-683 FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Mos 0.05 mg
27-412 EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. Human EB1 family proteins, which i 0.1 mg
orb41775 VCP antibody Polyclonal Rabbit polyclonal to VCP. The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S pro 100
29-337 STAU1 (Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and_or localization of mRNAs to different subcellular compartments and_or organelles 0.1 mg
29-336 STAU1 (Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and_or localization of mRNAs to different subcellular compartments and_or organelles 0.05 mg
29-931 Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, which contains 12 transmembrane domains and a number of critical conserved residues.Hexose transp 0.1 mg
28-103 The TRIM41 gene encodes a protein observed in the cytoplasm and the nucleus. Nuclear transport is mediated by an N-terminal segment common to both alpha and beta isoforms, but independent of a classic 0.05 mg

Pathways :

WP1780: ABC-family proteins mediated transport
WP1782: APC/C-mediated degradation of cell cycle proteins
WP1902: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
WP1922: SLC-mediated transmembrane transport
WP1887: Post-translational modification: synthesis of GPI-anchored proteins
WP1493: Carbon assimilation C4 pathway
WP1616: ABC transporters
WP295: Electron Transport Chain
WP1002: Electron Transport Chain
WP477: Cytoplasmic Ribosomal Proteins
WP1071: Cytoplasmic Ribosomal Proteins
WP1904: RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
WP2347: vitamin B5 (pantothenate) and CoA biosynthesis Pathway
WP1689: Porphyrin and chlorophyll metabolism
WP951: Integrin-mediated cell adhesion
WP59: Electron Transport Chain
WP1185: Integrin-mediated cell adhesion
WP1932: Transmembrane transport of small molecules
WP1256: NLR proteins
WP1937: Transport of vitamins, nucleosides, and related molecules
WP1826: GPVI-mediated activation cascade
WP74: Integrin-mediated cell adhesion
WP1845: MAPK targets/ Nuclear events mediated by MAP kinases
WP832: Integrin-mediated cell adhesion
WP1360: NLR proteins

Related Genes :
[ABCG37 ETA4 PDR12 PDR9 PIS1 At3g53480 F4P12.180] ABC transporter G family member 37 (ABC transporter ABCG.37) (AtABCG37) (Pleiotropic drug resistance protein 9) (Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 4) (Protein POLAR AUXIN TRANSPORT INHIBITOR SENSITIVE 1)
[DNAJC13 KIAA0678 RME8] DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)
[ABCG36 PDR8 PEN3 At1g59870 F23H11.19] ABC transporter G family member 36 (ABC transporter ABCG.36) (AtABCG36) (Pleiotropic drug resistance protein 8) (AtPDR8) (Protein PENETRATION 3)
[ABCB19 MDR1 MDR11 PGP19 At3g28860 MLD15.2] ABC transporter B family member 19 (ABC transporter ABCB.19) (AtABCB19) (Multidrug resistance protein 11) (P-glycoprotein 19)
[ABCB1 MDR1 PGP1 At2g36910 T1J8.9] ABC transporter B family member 1 (ABC transporter ABCB.1) (AtABCB1) (Multidrug resistance protein 1) (P-glycoprotein 1) (AtPgp1)
[ABCA1 ABC1 CERP] Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)
[ABCG40 PDR12 PDR9 At1g15520 T16N11.3] ABC transporter G family member 40 (ABC transporter ABCG.40) (AtABCG40) (Pleiotropic drug resistance protein 12)
[ABCF1 ABC50] ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)
[ABCG30 PDR2 At4g15230/At4g15220 dl3660w/dl3655w FCAALL.241] ABC transporter G family member 30 (ABC transporter ABCG.30) (AtABCG30) (Pleiotropic drug resistance protein 2) (AtPDR2)
[ABCG31 PDR3 At2g29940 F23F1.14] ABC transporter G family member 31 (ABC transporter ABCG.31) (AtABCG31) (Pleiotropic drug resistance protein 3) (AtPDR3)
[HMMR IHABP RHAMM] Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)
[ABCG25 WBC26 At1g71960 F17M19.11] ABC transporter G family member 25 (ABC transporter ABCG.25) (AtABCG25) (White-brown complex homolog protein 26) (AtWBC26)
[ABCG14 INT211 WBC14 At1g31770 F27M3.2 F5M6.22] ABC transporter G family member 14 (ABC transporter ABCG.14) (AtABCG14) (Protein INSENSITIVE TO TEMPERATURE 211) (White-brown complex homolog protein 14) (AtWBC14)
[TGD1 ABCI14 At1g19800 F14P1.27] Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic (ABC transporter I family member 14) (ABC transporter ABCI.14) (AtABCI14)
[ABCB4 MDR4 PGP4 At2g47000 F14M4.17] ABC transporter B family member 4 (ABC transporter ABCB.4) (AtABCB4) (Multidrug resistance protein 4) (P-glycoprotein 4)
[ABCC4 MOATB MRP4] ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4)
[ABCA7] Phospholipid-transporting ATPase ABCA7 (EC 7.6.2.1) (ABCA-SSN) (ATP-binding cassette sub-family A member 7) (Autoantigen SS-N) (Macrophage ABC transporter)
[ABCG1 ABC8 WHT1] ATP-binding cassette sub-family G member 1 (EC 7.6.2.-) (ATP-binding cassette transporter 8) (White protein homolog)
[ABCG26 WBC27 At3g13220 MJG19.19] ABC transporter G family member 26 (ABC transporter ABCG.26) (AtABCG26) (Putative white-brown complex homolog protein 27) (AtWBC27)
[ABCC5 MRP5 At1g04120 F20D22.11] ABC transporter C family member 5 (ABC transporter ABCC.5) (AtABCC5) (EC 7.6.2.2) (ATP-energized glutathione S-conjugate pump 5) (Glutathione S-conjugate-transporting ATPase 5) (Multidrug resistance-associated protein 5)
[ABCA3 ABC3] Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form]
[ABCB9 KIAA1520] ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL)
[ABCA4 ABCR] Retinal-specific phospholipid-transporting ATPase ABCA4 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Retinal-specific ATP-binding cassette transporter) (Stargardt disease protein)
[ABCA8 KIAA0822] ABC-type organic anion transporter ABCA8 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 8)
[ABCA2 ABC2 KIAA1062] ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2)
[Txlng Lrg] Gamma-taxilin (Factor inhibiting ATF4-mediated transcription) (FIAT) (Lipopolysaccharide-responsive gene protein)
[RMI1 C9orf76] RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75)
[KCTD10 ULR061 MSTP028] BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)
[Abca8b Abca8 Kiaa0822] ABC-type organic anion transporter ABCA8B (EC 7.6.2.-) (ATP-binding cassette sub-family A member 8B)
[Abca4 Abcr] Retinal-specific phospholipid-transporting ATPase ABCA4 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Retinal-specific ATP-binding cassette transporter)

Bibliography :
[31571167] Transporter-Mediated Drug-Drug Interactions and Their Significance.
[31571164] ABC Family Transporters.
[31571163] Overview: Role of Drug Transporters in Drug Disposition and Its Clinical Significance.
[27977217] Identification and Characterization of Trimethylamine-N-oxide Uptake and Efflux Transporters.
[26910071] Fluorimetric Methods for Analysis of Permeability, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter.
[25751674] The capability of Pseudomonas aeruginosa to recruit zinc under conditions of limited metal availability is affected by inactivation of the ZnuABC transporter.
[23992118] A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.
[23108027] Hijacking membrane transporters for arsenic phytoextraction.
[19470507] Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.
[19416657] Emerging new paradigms for ABCG transporters.