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Complement cascade

pathways : Complement cascade pathways:

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Related Genes to "Complement cascade" content :

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Related products :

Catalog number Product name Quantity
PR-945 Human Factor Xa Serine endoprotease from the coagulation cascade human plasma 10
PR-945 Human Factor Xa Serine endoprotease from the coagulation cascade human plasma 50µg
PR-945 Human Factor Xa Serine endoprotease from the coagulation cascade human plasma 50 µg
25-959 GPR177 has signal transducer activity. It is positive regulation of I-kappaB kinase_NF-kappaB cascade. 0.05 mg
25-185 RCVRN is a member of the recoverin family of neuronal calcium sensors. The protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in th 0.05 mg
29-567 Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl prote 0.1 mg
25-721 Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaini 0.05 mg
26-803 Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for in 0.05 mg
25-720 F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form b 0.05 mg
28-817 RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina 0.05 mg
29-637 F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form b 0.05 mg
orb61099 Sorafenib, p-Toluenesulfonate Salt Sorafenib Tosylate is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF_MEK_ERK cascade inhibitor with an IC50 of 6, 2 300 mg
orb61289 Sorafenib (free base) Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF_MEK_ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for 100 mg
orb61100 Sorafenib, Free Base Sorafenib Tosylate is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF_MEK_ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for R 300 mg
orb60095 Sorafenib Tosylate Sorafenib Tosylate is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF_MEK_ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf 10 mg
25-948 Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growt 0.05 mg
20-783-74967 MOUSE ANTI HUMAN C4c - COMPLEMENT COMPONENT 4c; Basic complement C4 Monoclonal 0.1 mg
orb82272 Complement C1q protein Complement C1q is a purified protein_bioactive peptide. For research use only. 1 mg
IHM-COMPL Animal Biologicals Complement Serum Complement Preserved Syrian Gold Hamster 5ml
IHM-COMPL Animal Biologicals Complement Serum Complement Preserved Syrian Gold Hamster 10ml
IHM-COMPL Animal Biologicals Complement Serum Complement Preserved Syrian Gold Hamster 25ml
CC-001 ProceptorTM C1q-CIC, Complement C1q bound to CIC ELISA kit- measuring immune complexes and complement system activation
CC-005 ProceptorTM C5-CIC, Complement C5 bound to CIC ELISA kit- measuring immune complexes and complement system activation
CC-004 ProceptorTM C4-CIC, Complement C4 bound to CIC ELISA kit- measuring immune complexes and complement system activation
CC-003 ProceptorTM C3-CIC, Complement C3 bound to CIC ELISA kit- measuring immune complexes and complement system activation

Pathways :

WP938: Complement and Coagulation Cascades
WP449: Complement and Coagulation Cascades
WP547: Complement and Coagulation Cascades
WP2328: Allograft rejection
WP820: Complement and Coagulation Cascades
WP1172: Complement and Coagulation Cascades
WP1056: Complement and Coagulation Cascades
WP558: Complement and Coagulation Cascades
WP1798: Complement cascade
WP402: ERK1 - ERK2 MAPK cascade
WP1009: MAPK Cascade
WP1122: Blood Clotting Cascade
WP1343: MAPK Cascade
WP775: Blood Clotting Cascade
WP1826: GPVI-mediated activation cascade
WP892: MAPK Cascade
WP272: Blood Clotting Cascade
WP446: MAPK Cascade
WP1095: Complement Activation, Classical Pathway
WP545: Complement Activation, Classical Pathway
WP751: Complement Activation, Classical Pathway
WP1818: Formation of Fibrin Clot (Clotting Cascade)
WP200: Complement Activation, Classical Pathway
WP81: Complement Activation, Classical Pathway
WP887: Blood Clotting Cascade

Related Genes :
[C3] Complement C3 (HSE-MSF) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
[C3] Complement C3 [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc) (Neutrophil chemotactic factor-2) (ENCF-2); Complement C3 alpha chain; C3a anaphylatoxin (Neutrophil chemotactic factor-1) (ENCF-1); Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
[C3 CPAMD1] Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
[C4A CO4 CPAMD2] Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]
[C4B CO4 CPAMD3; C4B_2] Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain]
[C5 Hc] Complement C5 (Hemolytic complement) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain]
[CFB BF BFD] Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment]
[C5 CPAMD4] Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain]
[C1S] Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain]
[C1R] Complement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain]
[C4b C4] Complement C4-B [Cleaved into: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain]
[C4 C4a] Complement C4 [Cleaved into: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain]
[CLU APOJ CLI KUB1 AAG4] Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)]
[C2] Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]
[CFI IF] Complement factor I (EC 3.4.21.45) (C3B/C4B inactivator) [Cleaved into: Complement factor I heavy chain; Complement factor I light chain]
[C9] Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]
[C8A] Complement component C8 alpha chain (Complement component 8 subunit alpha)
[C8B] Complement component C8 beta chain (Complement component 8 subunit beta)
[Cr1l Crry Cry] Complement component receptor 1-like protein (Complement regulatory protein Crry) (Protein p65)
[CR2 C3DR] Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21)
[Cr1l Crry] Complement component receptor 1-like protein (Antigen 5I2) (Complement regulatory protein Crry)
[Adipoq Acdc Acrp30 Apm1] Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipocyte-specific protein AdipoQ)
[Cfi If] Complement factor I (EC 3.4.21.45) (C3B/C4B inactivator) [Cleaved into: Complement factor I heavy chain; Complement factor I light chain]
[CD55 CR DAF] Complement decay-accelerating factor (CD antigen CD55)
[C3] C3-beta-c (C3a anaphylatoxin) (Complement C3) (Complement C3 beta chain) (Complement C3b alpha' chain) (Complement C3c alpha' chain fragment 1) (Complement C3c alpha' chain fragment 2) (Complement C3d fragment) (Complement C3dg fragment) (Complement C3f fragment) (Complement C3g fragment)
[CFHR5 CFHL5 FHR5] Complement factor H-related protein 5 (FHR-5)
[C8b] Complement component C8 beta chain (Complement component 8 subunit beta)
[C5AR2 C5L2 GPR77] C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
[CFH HF HF1 HF2] Complement factor H (H factor 1)
[CR1 C3BR] Complement receptor type 1 (C3b/C4b receptor) (CD antigen CD35)

Bibliography :
[35088000] [Polymorphism of the mannose-binding lectin gene in the Arctic indigenous populations of the Russian Federation].
[35087765] A Novel Cleavage Pattern of Complement C5 Induced by Infection the Chlamydial Protease CPAF.
[35087521] Shaping the Innate Immune Response Through Post-Transcriptional Regulation of Gene Expression Mediated by RNA-Binding Proteins.
[35087028] The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation.
[35086536] Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways.
[35085285] Involvement of enhanced expression of classical complement C1q in atherosclerosis progression and plaque instability: C1q as an indicator of clinical outcome.
[35083404] Prevalence of the polymorphic H-f icolin (FCN3) genes and mannose-binding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions.
[35082906] Curcumin-Based Inhibitors of Thrombosis and Cancer Metastasis Promoting Factor CLEC 2 from Traditional Medicinal Species .
[35082905] Alpha-Mangostin Activates MOAP-1 Tumor Suppressor and Mitochondrial Signaling in MCF-7 Human Breast Cancer Cells.
[35079732] Effect of resident complement on timeliness of stroke team activation in an academic emergency department.